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  1. Book: Tasman’s Psychiatry

    Tasman, Allan / Riba, Michelle B. / Alarcón, Renato D. / Alfonso, César A. / Kanba, Shigenobu / Lecic-Tosevski, Dusica / Ndetei, David M. / Ng, Chee H. / Schulze, Thomas G.

    2023  

    Abstract: This book is the first comprehensive reference work to cover the entire field of psychiatry in an updateable format and is designed specifically to keep up with emerging trends and models of care in rapidly evolving fields. Written by veterans in ... ...

    Author's details Allan Tasman, MD, DFAPA, FRCP§Professor and Emeritus Chairman§Department of Psychiatry and Behavioral Sciences§Schwab Endowed Chair in Social, Community, and Family Psychiatry§University of Louisville School of Medicine§401 East Chestnut Street Suite 600§Louisville, Kentucky 40202§Past President American Psychiatric Association§Past Secretary for Education, World Psychiatric Association§Chair, Section on Education, World Psychiatric Association§Editor Emeritus, Psychiatric Times§Editor in Chief, Asia Pacific Psychiatry§Editor in Chief (Americas), Mental Health in Family Medicine§§Jerald Kay, MD§Chairman and Professor Emeritus§Wright State University§§Michael B. First, MD§Professor of Clinical Psychiatry§Columbia University§§Michelle B. Riba, MD§§Thomas G. Schulze, MD§Professor Institute of Psychiatric Phenomics and Genomics§University of Munich§§Chee Ng, MBBS, MD§Healthscope Chair of Psychiatry§Professor, Department of Psychiatry§University of Melbourne§§César A. Alfonso, MD§Associa
    Abstract This book is the first comprehensive reference work to cover the entire field of psychiatry in an updateable format and is designed specifically to keep up with emerging trends and models of care in rapidly evolving fields. Written by veterans in psychiatry and medical education, this edition builds on 20 years of editions at the forefront of the field, covering topics not only clinical chapters on disease entities and their various treatments, but also sections on normal human development, t...
    Keywords MHMO045 ; SPSP ; NBIA065 ; Psychiatric education ; Fundamentals of psychiatry ; Psychiatric disorders ; Consultation and Liaison Psychiatry ; Collaborative Care ; Mental health treatment
    Language English
    Size 3000 p.
    Edition 5
    Publisher Springer International Publishing
    Document type Book
    Note PDA Manuell_18
    Format 178 x 254
    ISBN 9783030513658 ; 3030513653
    Database PDA

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  2. Book: Men¿s Health and Wellbeing

    Goonewardene, Sanchia S. / Ahmed, Kamran / Albala, David / Brunckhorst, Oliver

    2022  

    Author's details Sanchia Goonewardene qualified from Birmingham Medical School with Honours in Clinical Science and a BMedSc Degree in Medical Genetics and Molecular Medicine. She has served on the EAU Guidelines Panel on Chronic Pelvic Pain. She has been an MSc Thesis examiner for the University of Edinburgh/ Royal College of Surgeons of Edinburgh ESSQ course. She is an Associate Editor for the Journal of Robotic Surgery and is on the review board of BMJ case reports. Additionally, she is on the working group of The International Continence Society Terminology Panel on Pelvic Floor Dysfunction and Male LUTS and the Good Urodynamic Practice Panel. She has published 6 books and is Series Editor for Management of Urology, Springer Nature. Her first book published, an Edited volume has since ranked Number 3 in Book Authority's 100 Best Urology Books of all Time. Dr. David M. Albala graduated with a geology degree from Lafayette College in Easton, Pennsylvania. He completed his medical school training
    Keywords infertility ; survivorship ; Metabolic Syndrome ; hormones ; Benign prostate ; Infertility ; Survivorship ; Hormones
    Language English
    Size 496 p.
    Edition 1
    Publisher Springer International Publishing
    Document type Book
    Note PDA Manuell_13
    Format 160 x 241 x 31
    ISBN 9783030847517 ; 3030847519
    Database PDA

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  3. Article ; Online: S

    Bahig, Houda / Tonneau, Marion / Blais, Normand / Wong, Philip / Filion, Edith / Campeau, Marie-Pierre / Vu, Toni / Al-Saleh, Afnan / Tehfé, Mustapha / Florescu, Marie / Roberge, David / Masucci, Laura / Richard, Corentin / Menard, Cynthia / Routy, Bertrand

    Clinical and translational radiation oncology

    2022  Volume 33, Page(s) 115–119

    Abstract: Background: Management of Non-Small Cell Lung Cancer (NSCLC) patients with oligoprogression remains controversial. There is limited data to support the strategy of Stereotactic Ablative Radiotherapy (SABR) targeting the oligoprogressive disease in ... ...

    Abstract Background: Management of Non-Small Cell Lung Cancer (NSCLC) patients with oligoprogression remains controversial. There is limited data to support the strategy of Stereotactic Ablative Radiotherapy (SABR) targeting the oligoprogressive disease in combination with ongoing systemic treatment. We aim to assess the benefit of this approach compared to standard of care in the treatment of oligoprogressive NSCLC.
    Methods: This phase II study will enroll 68 patients with oligoprogressive NSCLC, defined as 1-5 progressive extracranial lesions ≤5 cm involving ≤3 organs. Patients on active systemic therapy (chemotherapy, immunotherapy, targeted therapy or a combination) will be randomized 1:1 to either continue their current systemic therapy in combination with SABR to all lesions or the standard of care (switch to the next line of treatment, continue same treatment or observation). The co-primary endpoints are progression-free survival (PFS) and overall survival (OS). Secondary endpoints include time to next systemic treatment, patient-reported quality of life, cost effectiveness as well as translational analysis to characterize both adaptive immunity and immunogenic cell death markers in the peripheral blood.
    Discussion: There is an unmet need to carefully examine the efficacy, safety and quality of life impact of SABR in the context of oligoprogressive disease. The present study will provide higher level randomized evidence on the role of SABR in oligoprogressive NSCLC.
    Language English
    Publishing date 2022-01-05
    Publishing country Ireland
    Document type Journal Article
    ISSN 2405-6308
    ISSN (online) 2405-6308
    DOI 10.1016/j.ctro.2021.12.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Online ; E-Book: David A. Robinson’s modeling the oculomotor control system

    Robinson, David Adair / Anastasio, Thomas

    (Progress in brain research ; volume 267)

    2022  

    Title variant Modeling the oculomotor control system
    Author's details edited by Thomas Anastasio [and 7 others]
    Series title Progress in brain research ; volume 267
    Collection
    Keywords Eye / Movements / Mathematical models ; Motor neurons / Physiology ; Eye ; Movements ; Mathematical models
    Language English
    Size 1 Online-Ressource (xxiv, 435 Seiten)
    Edition First edition
    Publisher Elsevier
    Publishing place Amsterdam
    Publishing country Netherlands
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021866592
    ISBN 978-0-323-99218-3 ; 0-323-99218-8 ; 9780323992176 ; 032399217X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  5. Article: S-Nitrosation of

    Nicolas-Francès, Valérie / Rossi, Jordan / Rosnoblet, Claire / Pichereaux, Carole / Hichami, Siham / Astier, Jeremy / Klinguer, Agnès / Wendehenne, David / Besson-Bard, Angélique

    Frontiers in plant science

    2022  Volume 13, Page(s) 807249

    Abstract: Tyrosine-specific protein tyrosine phosphatases (Tyr-specific PTPases) are key signaling enzymes catalyzing the removal of the phosphate group from phosphorylated tyrosine residues on target proteins. This post-translational modification notably allows ... ...

    Abstract Tyrosine-specific protein tyrosine phosphatases (Tyr-specific PTPases) are key signaling enzymes catalyzing the removal of the phosphate group from phosphorylated tyrosine residues on target proteins. This post-translational modification notably allows the regulation of mitogen-activated protein kinase (MAPK) cascades during defense reactions.
    Language English
    Publishing date 2022-02-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2022.807249
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Feasibility, safety, and impact of the RTS,S/AS01

    Asante, Kwaku Poku / Mathanga, Don P / Milligan, Paul / Akech, Samuel / Oduro, Abraham / Mwapasa, Victor / Moore, Kerryn A / Kwambai, Titus K / Hamel, Mary J / Gyan, Thomas / Westercamp, Nelli / Kapito-Tembo, Atupele / Njuguna, Patricia / Ansong, Daniel / Kariuki, Simon / Mvalo, Tisungane / Snell, Paul / Schellenberg, David / Welega, Paul /
    Otieno, Lucas / Chimala, Alfred / Afari, Edwin A / Bejon, Philip / Maleta, Kenneth / Agbenyega, Tsiri / Snow, Robert W / Zulu, Madaliso / Chinkhumba, Jobiba / Samuels, Aaron M

    Lancet (London, England)

    2024  

    Abstract: Background: The RTS,S/AS01: Methods: In this prospective evaluation, 158 geographical clusters ... in Malawi) were randomly assigned to early or delayed introduction of RTS,S, with three doses to be ... for widespread use of RTS,S in areas of moderate-to-high malaria transmission.: Findings: By April 30, 2021 ...

    Abstract Background: The RTS,S/AS01
    Methods: In this prospective evaluation, 158 geographical clusters (66 districts in Ghana; 46 sub-counties in Kenya; and 46 groups of immunisation clinic catchment areas in Malawi) were randomly assigned to early or delayed introduction of RTS,S, with three doses to be administered between the ages of 5 months and 9 months and a fourth dose at the age of approximately 2 years. Primary outcomes of the evaluation, planned over 4 years, were mortality from all causes except injury (impact), hospital admission with severe malaria (impact), hospital admission with meningitis or cerebral malaria (safety), deaths in girls compared with boys (safety), and vaccination coverage (feasibility). Mortality was monitored in children aged 1-59 months throughout the pilot areas. Surveillance for meningitis and severe malaria was established in eight sentinel hospitals in Ghana, six in Kenya, and four in Malawi. Vaccine uptake was measured in surveys of children aged 12-23 months about 18 months after vaccine introduction. We estimated that sufficient data would have accrued after 24 months to evaluate each of the safety signals and the impact on severe malaria in a pooled analysis of the data from the three countries. We estimated incidence rate ratios (IRRs) by comparing the ratio of the number of events in children age-eligible to have received at least one dose of the vaccine (for safety outcomes), or age-eligible to have received three doses (for impact outcomes), to that in non-eligible age groups in implementation areas with the equivalent ratio in comparison areas. To establish whether there was evidence of a difference between girls and boys in the vaccine's impact on mortality, the female-to-male mortality ratio in age groups eligible to receive the vaccine (relative to the ratio in non-eligible children) was compared between implementation and comparison areas. Preliminary findings contributed to WHO's recommendation in 2021 for widespread use of RTS,S in areas of moderate-to-high malaria transmission.
    Findings: By April 30, 2021, 652 673 children had received at least one dose of RTS,S and 494 745 children had received three doses. Coverage of the first dose was 76% in Ghana, 79% in Kenya, and 73% in Malawi, and coverage of the third dose was 66% in Ghana, 62% in Kenya, and 62% in Malawi. 26 285 children aged 1-59 months were admitted to sentinel hospitals and 13 198 deaths were reported through mortality surveillance. Among children eligible to have received at least one dose of RTS,S, there was no evidence of an excess of meningitis or cerebral malaria cases in implementation areas compared with comparison areas (hospital admission with meningitis: IRR 0·63 [95% CI 0·22-1·79]; hospital admission with cerebral malaria: IRR 1·03 [95% CI 0·61-1·74]). The impact of RTS,S introduction on mortality was similar for girls and boys (relative mortality ratio 1·03 [95% CI 0·88-1·21]). Among children eligible for three vaccine doses, RTS,S introduction was associated with a 32% reduction (95% CI 5-51%) in hospital admission with severe malaria, and a 9% reduction (95% CI 0-18%) in all-cause mortality (excluding injury).
    Interpretation: In the first 2 years of implementation of RTS,S, the three primary doses were effectively deployed through national immunisation programmes. There was no evidence of the safety signals that had been observed in the phase 3 trial, and introduction of the vaccine was associated with substantial reductions in hospital admission with severe malaria. Evaluation continues to assess the impact of four doses of RTS,S.
    Funding: Gavi, the Vaccine Alliance; the Global Fund to Fight AIDS, Tuberculosis and Malaria; and Unitaid.
    Language English
    Publishing date 2024-04-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(24)00004-7
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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.5: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 94: Show issues

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  7. Article ; Online: S

    van Gerven, David / Wickleder, Mathias S

    Angewandte Chemie (International ed. in English)

    2020  Volume 59, Issue 39, Page(s) 17169–17171

    Abstract: The reaction of hexachlorophosphazene, ... ...

    Abstract The reaction of hexachlorophosphazene, P
    Language English
    Publishing date 2020-08-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202005056
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  8. Article ; Online: S

    Lee, Heui Beom / Marchiori, David A / Chatterjee, Ruchira / Oyala, Paul H / Yano, Junko / Britt, R David / Agapie, Theodor

    Journal of the American Chemical Society

    2020  Volume 142, Issue 8, Page(s) 3753–3761

    Abstract: The S ...

    Abstract The S
    MeSH term(s) Coordination Complexes/chemistry ; Manganese Compounds/chemistry ; Oxidation-Reduction ; Oxides/chemistry ; Oxygen/chemistry ; Spectrum Analysis/methods
    Chemical Substances Coordination Complexes ; Manganese Compounds ; Oxides ; manganese oxide (64J2OA7MH3) ; Oxygen (S88TT14065)
    Language English
    Publishing date 2020-02-18
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.9b10371
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    In stock of ZB MED Bonn / Germany

    Z 4' 55/32: Show issues
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  9. Article ; Online: Remembering Fred S. Wright, M.D. (1937-2023).

    Aronson, Peter S / Ellison, David H / Okusa, Mark D / Perazella, Mark A

    Kidney360

    2024  

    Language English
    Publishing date 2024-04-03
    Publishing country United States
    Document type Journal Article
    ISSN 2641-7650
    ISSN (online) 2641-7650
    DOI 10.34067/KID.0000000000000438
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  10. Article ; Online: Improved automated one-pot two-step radiosynthesis of (S)-[

    Maisonial-Besset, Aurélie / Kryza, David / Kopka, Klaus / Levesque, Sophie / Moreau, Emmanuel / Wenzel, Barbara / Chezal, Jean-Michel

    EJNMMI radiopharmacy and chemistry

    2024  Volume 9, Issue 1, Page(s) 28

    Abstract: Background: (S)-[: Results: Enantiomerically pure (S)- and (R)-FETrp references as well ... as tosylate precursors (S)- and (R)-3 were obtained from corresponding N: Conclusions: To avoid ... racemisation and complicated purification processes, currently encountered for the radiosynthesis of (S)-[ ...

    Abstract Background: (S)-[
    Results: Enantiomerically pure (S)- and (R)-FETrp references as well as tosylate precursors (S)- and (R)-3 were obtained from corresponding N
    Conclusions: To avoid racemisation and complicated purification processes, currently encountered for the radiosynthesis of (S)-[
    Language English
    Publishing date 2024-04-02
    Publishing country England
    Document type Journal Article
    ISSN 2365-421X
    ISSN (online) 2365-421X
    DOI 10.1186/s41181-024-00256-0
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