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Article: Unveiling the Unlikely: Extraskeletal Ewing Sarcoma Masquerading as Gastrointestinal Bleeding.

Greenfield, Bryan M / Wilson, Madeleine A / Schulte, Kyle J / Silverstein, Stephen

2024 Volume 16, Issue 3, Page(s) e57109

Abstract: While Ewing sarcoma is traditionally a malignant tumor of bone, it may uncommonly present extra-skeletally, leading to an array of puzzling presentations depending on the tissue involved. Here, we describe the case of a 66-year-old man who presented to ... ...

Abstract	While Ewing sarcoma is traditionally a malignant tumor of bone, it may uncommonly present extra-skeletally, leading to an array of puzzling presentations depending on the tissue involved. Here, we describe the case of a 66-year-old man who presented to the primary care office for evaluation of intermittent melena. He ultimately underwent capsule endoscopy and developed a secondary small bowel obstruction, unveiling his neoplasm. The tumor was then resected and managed with surveillance only, and the patient remains without evidence of disease after four years of follow-up.
Language	English
Publishing date	2024-03-28
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.57109
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Article ; Online: Attitudes and experiences with fentanyl contamination of methamphetamine: exploring self-reports and urine toxicology among persons who use methamphetamine and other drugs.

Daniulaityte, Raminta / Ruhter, Lance / Juhascik, Matthew / Silverstein, Sydney

Harm reduction journal

2023 Volume 20, Issue 1, Page(s) 54

Abstract: Background: There are growing concerns about illicitly manufactured fentanyl (IMF) contamination of methamphetamine. This study aims to characterize the lay views and experiences with IMF-contaminated methamphetamine (IMF/meth) and identify participants ...

Abstract	Background: There are growing concerns about illicitly manufactured fentanyl (IMF) contamination of methamphetamine. This study aims to characterize the lay views and experiences with IMF-contaminated methamphetamine (IMF/meth) and identify participants with unknown IMF exposures through urine toxicology analysis. Methods: Between December-2019 and November-2021, structured interviews were conducted with 91 individuals who reported past 30-day use of methamphetamine and resided in Dayton, Ohio, USA. Lab-based urine toxicology analyses were conducted to identify fentanyl/analogs, methamphetamine, and other drugs. Bivariate analyses were conducted to identify characteristics associated with attitudes and experiences with IMF/meth, and unknown IMF exposures. Results: The majority (95.6%) of the study participants were non-Hispanic white, and 52.7% were female. Past 30-day use of methamphetamine was reported on a mean of 18.7 (SD 9.1) days, and 62.6% also reported past 30-day use of heroin/IMF. Most (76.9%) had a history of an unintentional drug-related overdose, but 38.5% rated their current risk for an opioid overdose as none. Besides fentanyl (71.9%), toxicology analysis identified nine fentanyl analogs/metabolites (e.g., 42.7% acetyl fentanyl, 19.0% fluorofentanyl, 5.6% carfentanil), and 12.4% tested positive for Xylazine. The majority (71.4%) believed that IMF/meth was common, and 59.3% reported prior exposures to IMF/meth. 11.2% tested positive for IMF but reported no past 30-day heroin/IMF use (unknown exposure to IMF). Views that IMF/meth was common showed association with homelessness (p = 0.04), prior overdose (p = 0.028), and greater perceived risk of opioid overdose (p = 0.019). Self-reported exposure to IMF/meth was associated with homelessness (p = 0.007) and obtaining take-home naloxone (p = 0.025). Individuals with unknown IMF exposure (test positive for IMF, no reported past 30-day heroin/IMF use) were older (49.9 vs. 41.1 years, p < 0.01), and reported more frequent past 30-day use of methamphetamine (24.4 vs. 18.0 days, p < 0.05). They indicated lower perceived risk of opioid overdose (0.1 vs. 1.9, scale from 0 = "none" to 4 = "high," p < 0.001). Discussion: This study suggests a need for targeted interventions for people who use methamphetamine and expansion of drug checking and other harm reduction services.
MeSH term(s)	Humans ; Male ; Female ; Analgesics, Opioid ; Self Report ; Heroin ; Methamphetamine ; Opiate Overdose ; Fentanyl ; Drug Overdose/epidemiology
Chemical Substances	Analgesics, Opioid ; Heroin (70D95007SX) ; Methamphetamine (44RAL3456C) ; Fentanyl (UF599785JZ)
Language	English
Publishing date	2023-04-20
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2146691-9
ISSN	1477-7517 ; 1477-7517
ISSN (online)	1477-7517
ISSN	1477-7517
DOI	10.1186/s12954-023-00782-1
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Article ; Online: How well does the Index of Race-Related Stress-brief function in a trauma-exposed Black community sample? An item response theory examination of discrimination and difficulty parameters.

Mekawi, Yara / Silverstein, Madison W / Belizaire, Shequanna / Ware, Maryam / Powers, Abigail / Carter, Sierra

Psychological trauma : theory, research, practice and policy

2024

Abstract: Background: Race-related stress negatively impacts the mental health of Black Americans to a greater degree than other racialized groups. Additionally, trauma exposure is associated with more severe levels of posttraumatic stress disorder for ... ...

Abstract	Background: Race-related stress negatively impacts the mental health of Black Americans to a greater degree than other racialized groups. Additionally, trauma exposure is associated with more severe levels of posttraumatic stress disorder for individuals who also experience race-related stress. Therefore, an accurate assessment of race-related stress in a trauma-exposed sample of Black Americans is necessary to ensure the validity and reliability of empirical findings regarding race-related stress and intervention efficacy. The Index of Race-Related Stress (IRRS) is one of the most commonly used measures to assess race-related stress among Black Americans. Due to a lack of psychometric support for the abbreviated version of IRRS-brief (IRRS-B) on a trauma-exposed sample of Black Americans, our study aims to address this gap in literature. Method: We used item response theory (IRT) to assess item difficulty, discrimination, and factor structure in a sample of trauma-exposed Black Americans ( Results: The most discriminating items asked about observing harsh treatment of Black individuals, experiencing less courtesy in establishments, and being stared at as though you do not belong. The item with the lowest difficulty described negative media representation of Black individuals while the item with the highest difficulty described lack of positive media portrayals of Black Americans. Discussion: These results indicate that items varied considerably in the degree to which they adequately captured race-related stress. Future research should use IRT with newly worded questions to further improve the assessment of race-related stress in Black Americans. (PsycInfo Database Record (c) 2024 APA, all rights reserved).
Language	English
Publishing date	2024-01-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	2497028-1
ISSN	1942-969X ; 1942-9681
ISSN (online)	1942-969X
ISSN	1942-9681
DOI	10.1037/tra0001645
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Article ; Online: Guidelines for research with transgender, gender diverse, and intersex individuals with eating disorders: recommendations from trans and intersex researchers.

Urban, Bek / Smith, Emil K / Adams, Marissa / Sharpe, Sam L / Silverstein, Scout

Eating disorders

2024 , Page(s) 1–12

Abstract: Further research is urgently needed to address the disproportionately high rates of eating disorders (EDs) among transgender, gender diverse, and intersex (TGDI) individuals in comparison to cisgender, endosex (non-intersex) populations. As TGDI ... ...

Abstract	Further research is urgently needed to address the disproportionately high rates of eating disorders (EDs) among transgender, gender diverse, and intersex (TGDI) individuals in comparison to cisgender, endosex (non-intersex) populations. As TGDI advocates, academics, and clinicians with lived/living experience with EDs, we propose a set of recommendations to guide ethical research specifically about EDs and disordered eating behaviors in TGDI populations. The guidelines included here aim to educate non-TGDI researchers and support TGDI researchers seeking to carry out such research. Considerations for study design, planning, data collection, and dissemination are included.
Language	English
Publishing date	2024-02-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	1209799-8
ISSN	1532-530X ; 1064-0266 ; 1067-1633
ISSN (online)	1532-530X
ISSN	1064-0266 ; 1067-1633
DOI	10.1080/10640266.2024.2306436
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Article ; Online: The Undervalued Potential of Medical-Psychiatry Units to Improve Care for People With Severe Mental Illnesses.

Wittink, Marsha / Chan, Aubrey C / Padrino, Susan / Silverstein, Steven M

Psychiatric services (Washington, D.C.)

2023 Volume 74, Issue 9, Page(s) 991–993

MeSH term(s)	Humans ; Mental Disorders/therapy ; Psychiatry
Language	English
Publishing date	2023-02-23
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1220173-x
ISSN	1557-9700 ; 1075-2730
ISSN (online)	1557-9700
ISSN	1075-2730
DOI	10.1176/appi.ps.202200039
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Article ; Online: OCT and OCT Angiography Offer New Insights and Opportunities in Schizophrenia Research and Treatment.

Green, Kyle M / Choi, Joy J / Ramchandran, Rajeev S / Silverstein, Steven M

Frontiers in digital health

2022 Volume 4, Page(s) 836851

Abstract: The human retina and retinal imaging technologies continue to increasingly gain the attention of schizophrenia researchers. With the same embryologic origin as the brain, the retina offers a window into neurovascular changes that may underlie disease. ... ...

Abstract	The human retina and retinal imaging technologies continue to increasingly gain the attention of schizophrenia researchers. With the same embryologic origin as the brain, the retina offers a window into neurovascular changes that may underlie disease. Recently, two technologies that have already revolutionized the field of ophthalmology, optical coherence tomography (OCT), and a functional extension of this, optical coherence tomography angiography (OCTA), have gained traction. Together, these non-invasive technologies allow for microscopic imaging of both structural and vascular features of the retina. With ease of use and no side effects, these devices are likely to prove powerful digital health tools in the study and treatment of schizophrenia. They may also prove key to discovering disease relevant biomarkers that underly neurodevelopmental and neurodegenerative aspects of conditions such as schizophrenia.
Language	English
Publishing date	2022-02-18
Publishing country	Switzerland
Document type	Journal Article
ISSN	2673-253X
ISSN (online)	2673-253X
DOI	10.3389/fdgth.2022.836851
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Article ; Online: Are We Walking to the Future or to the Past? A Retrospective Analysis of Professional Nursing during the Pandemic of 2020, Dating back to the Crimean War, 1853-1856

Silverstein, Christine M.

Communication, Society and Media; Vol 3, No; p102 ; 2576-5396 ; 2576-5388

2020 Volume 3

Abstract: ... s reaction to it. Although counterintuitive, queries arise as to whether the Commander-in-Chief ...

Abstract	This retrospective analysis, based on facts derived from contemporary news media, videos, and journal articles, scrutinizes a White House televised ceremony that celebrated National Nurses Day on May 6, 2020 during the COVID-19 pandemic and the #MeToo movement. On the surface, it appears that nurses were honored by the President, but a deeper look beneath reveals otherwise. This historian explores two pivotal moments during the ceremony that changed the focus from a celebration to a campaign event, which occurred when a female nurse practitioner stepped out of line to posit that personal protective equipment was “sporadic” and President Trump’s reaction to it. Although counterintuitive, queries arise as to whether the Commander-in-Chief celebrated professional nursing or denigrated it, as nurses kowtowed to authoritarian rule and unwittingly abandoned the time-honored principles of facts, science, and caring in professional nursing extant since its inception. Retrospectively, documents from archives are examined and the biographies of two transformational leaders, Hildegard Peplau and Florence Nightingale. These questions are asked: In 2020 how would they uphold their high standards and teachings today that set the stage for the evolution of professional nursing? What role would therapeutic interpersonal interactions of caring in nursing play in the 21st century?
Keywords	covid19
Language	English
Publishing date	2020-08-17
Publisher	SCHOLINK CO.,LTD
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Retrospective evaluation of carboxyhemoglobin and methemoglobin levels in dogs and cats with respiratory disease.

Wolf, Jacob M / Hess, Rebecka S / Hering, Caitlin T / Silverstein, Deborah C

Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)

2022 Volume 32, Issue 5, Page(s) 637–644

Abstract: Objective: To evaluate carboxyhemoglobin (COHb) and methemoglobin (MetHb) levels in dogs and cats with respiratory disease in the ICU.: Design: Retrospective study.: Setting: University veterinary teaching hospital.: Animals: The ICU census was ...

Abstract	Objective: To evaluate carboxyhemoglobin (COHb) and methemoglobin (MetHb) levels in dogs and cats with respiratory disease in the ICU. Design: Retrospective study. Setting: University veterinary teaching hospital. Animals: The ICU census was searched for dogs (n = 466) and cats (n = 97) hospitalized within the ICU between January 2016 and January 2019 in whom blood gas with co-oximetry was performed. Dogs and cats were stratified into those with primary respiratory and nonrespiratory categories; the underlying cause of the disease was also noted. Venous blood gas, co-oximeter, PaO Measurements and main results: The median COHb and MetHb in dogs hospitalized in the ICU were 2.6% (0.1%-5.6%) and 1.1% (0.1%-2.9%), respectively. The median COHb and MetHb in cats hospitalized in the ICU were 2.2% (0.1%-5.4%) and 1.0% (0%-2.1%), respectively. Dogs with respiratory disease had a higher COHb than dogs without respiratory disease (median, 2.7% [range, 0.3%-5.0%] vs. 2.5% [0.1%-5.6%]; P = 0.0148). COHb was positively associated with survival in cats (median, 2.2% [range, 0.1%-5.4%] vs. 1.9% [0.1%-3.9%]; P = 0.0433). Both COHb and MetHb were higher in septic dogs than in nonseptic dogs (median COHb, 2.8% [range 0.3%-4.5%] vs. 2.6% [0.1%-5.6%]; P = 0.02 and median MetHb, 1.1% [0.1%-2.9%] vs. 1.1% [0.1%-2.4%]; P = 0.01, respectively). Conclusions: There may be a positive association between COHb and respiratory disease in dogs; prospective studies are needed to evaluate this further. No association between COHb and respiratory disease in cats or MetHb and respiratory disease in either species was detected. Additional prospective studies are needed to determine whether COHb and MetHb are biomarkers for sepsis in dogs and whether COHb is an indicator of mortality in cats.
MeSH term(s)	Animals ; Biomarkers ; Carboxyhemoglobin/analysis ; Cat Diseases ; Cats ; Dog Diseases ; Dogs ; Hospitals, Animal ; Hospitals, Teaching ; Humans ; Methemoglobin/analysis ; Oximetry/veterinary ; Retrospective Studies
Chemical Substances	Biomarkers ; Methemoglobin (9008-37-1) ; Carboxyhemoglobin (9061-29-4)
Language	English
Publishing date	2022-04-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	2077212-9
ISSN	1476-4431 ; 1479-3261
ISSN (online)	1476-4431
ISSN	1479-3261
DOI	10.1111/vec.13202
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Article ; Online: Pandemic response across Ohio's public universities: Novel approaches, emergent challenges and future opportunities.

Silverstein, Sydney M / Jenkins, Whitney / Orlowski, Marietta / Paton, Sara

Journal of American college health : J of ACH

2022 , Page(s) 1–10

Abstract: Objective: ...

Abstract	Objective:
Language	English
Publishing date	2022-09-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	604907-2
ISSN	1940-3208 ; 0744-8481
ISSN (online)	1940-3208
ISSN	0744-8481
DOI	10.1080/07448481.2022.2121923
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Zs.A 427: Show issues

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Article ; Online: Beyond Wokeness: Why We Should All Be Using a More "Sensitive" Measure of Self-Reported Gender Identity.

Marcotte, Melissa / Cichoń, Marta / DeSalvo, Nathan / Medeiros, Kayla / Gadbois, Stephen / Alberti-Silverstein, Jennifer

Psychological reports

2023 , Page(s) 332941221149178

Abstract: ... researchers in other areas. We analyzed responses from over 700 gender-diverse participants in the U.S ...

Abstract	Gender plays a significant role in an individual's experiences and behaviors, as well as their expectations of others. Researchers have long operationalized gender using limited, mutually exclusive categories that fail to capture the rich variability within a gender-diverse population. While open-ended responses or multi-item scales may be a socially progressive approach and necessary for some gender-based research (e.g., Bauer et al., 2017), it may be unsuitable and statistically unfeasible for quantitative researchers in other areas. We analyzed responses from over 700 gender-diverse participants in the U.S. on a series of unipolar scales (i.e., gender identity, expression, and perception by others) that granted participants the flexibility of selecting a comprehensive self-definition while still enabling quantitative analysis of group differences as well as capturing maximum within-group variability. Using a cluster analysis, we found that participants' responses were best represented by five categories:
Language	English
Publishing date	2023-01-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	205658-6
ISSN	1558-691X ; 0033-2941
ISSN (online)	1558-691X
ISSN	0033-2941
DOI	10.1177/00332941221149178
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