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  1. Book: Vitamin-D-Mangel

    Amrein, Karin / Amling, Michael

    aktuelle Diagnostik und Prophylaxe in Fallbeispielen

    (UNI-MED science)

    2019  

    Title variant Vitamin D-Mangel ; Vitamin-D-Mangel - aktuelle Diagnostik und Prophylaxe in Fallbeispielen
    Author's details Priv.-Doz. Dr. Karin Amrein, MSc ; unter Mitarbeit von Prof. Dr. Michael Amling, MBA [und 29 weiteren]
    Series title UNI-MED science
    Keywords Vitamin-D-Mangel
    Subject Vitamin D
    Language German
    Size 144 Seiten, Illustrationen, Diagramme, Karte, 25 cm
    Edition 2. Auflage
    Publisher UNI-MED Verlag AG
    Publishing place Bremen ; London ; Boston
    Publishing country Germany
    Document type Book
    Old title Vorangegangen ist
    HBZ-ID HT020381435
    ISBN 978-3-8374-1574-2 ; 3-8374-1574-0
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2020 A 735 on loan 0 Vormerkungen

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  2. Book: Vitamin-D-Mangel

    Amrein, Karin / Amling, Michael

    aktuelle Diagnostik und Prophylaxe in Fallbeispielen

    (UNI-MED Science)

    2015  

    Title variant Vitamin-D-Mangel - aktuelle Diagnostik und Prophylaxe in Fallbeispielen
    Author's details [Karin Amrein. Unter Mitarb. von Michael Amling ...]
    Series title UNI-MED Science
    Keywords Vitamin-D-Mangel
    Subject Vitamin D
    Language German
    Size 142 S. : Ill., graf. Darst., 61 Ill., 240 mm x 170 mm
    Edition 1. Aufl.
    Publisher UNI-MED
    Publishing place Bremen u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT018819124
    ISBN 978-3-8374-1453-0 ; 3-8374-1453-1
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2015 A 4018 available for loan (reading room) Lesesaal EG

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  3. Article ; Online: Continuation of enteral nutrition until extubation in critically ill patients.

    Lobmeyr, Elisabeth / Amrein, Karin

    The Lancet. Respiratory medicine

    2023  Volume 11, Issue 4, Page(s) 298–299

    MeSH term(s) Humans ; Enteral Nutrition ; Critical Illness/therapy ; Airway Extubation ; Energy Intake ; Time Factors
    Language English
    Publishing date 2023-01-21
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(22)00481-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 7041: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Editorial: micronutrients and functional foods.

    Amrein, Karin / Lukaski, Henry C

    Current opinion in clinical nutrition and metabolic care

    2023  Volume 26, Issue 6, Page(s) 541–542

    MeSH term(s) Humans ; Functional Food ; Micronutrients ; Food, Fortified
    Chemical Substances Micronutrients
    Language English
    Publishing date 2023-10-05
    Publishing country England
    Document type Editorial
    ZDB-ID 1460178-3
    ISSN 1473-6519 ; 1363-1950
    ISSN (online) 1473-6519
    ISSN 1363-1950
    DOI 10.1097/MCO.0000000000000982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5586: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Editorial: A potpourri of nutrition and metabolism in the ICU.

    Amrein, Karin / Martucci, Gennaro

    Current opinion in critical care

    2020  Volume 26, Issue 4, Page(s) 327–328

    MeSH term(s) Critical Illness ; Humans ; Intensive Care Units ; Nutritional Status
    Language English
    Publishing date 2020-05-25
    Publishing country United States
    Document type Editorial
    ZDB-ID 1235629-3
    ISSN 1531-7072 ; 1070-5295
    ISSN (online) 1531-7072
    ISSN 1070-5295
    DOI 10.1097/MCC.0000000000000732
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4999: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: An update of the effects of vitamins D and C in critical illness.

    Hill, Aileen / Starchl, Christina / Dresen, Ellen / Stoppe, Christian / Amrein, Karin

    Frontiers in medicine

    2023  Volume 9, Page(s) 1083760

    Abstract: Many critically ill patients are vitamin D and vitamin C deficient and the current international guidelines state that hypovitaminoses should be compensated. However, uncertainty about optimal dosage, timing and indication exists in clinical routine, ... ...

    Abstract Many critically ill patients are vitamin D and vitamin C deficient and the current international guidelines state that hypovitaminoses should be compensated. However, uncertainty about optimal dosage, timing and indication exists in clinical routine, mainly due to the conflicting evidence. This narrative review discusses both micronutrients with regards to pathophysiology, clinical evidence of benefits, potential risks, and guideline recommendations. Evidence generated from the most recent clinical trials are summarized and discussed. In addition, pragmatic tips for the application of these vitamins in the clinical routine are given. The supplementations of vitamin D and C represent cost-effective and simple interventions with excellent safety profiles. Regarding vitamin D, critically ill individuals require a loading dose to improve 25(OH)D levels within a few days, followed by a daily or weekly maintenance dose, usually higher doses than healthy individuals are needed. For vitamin C, dosages of 100-200 mg/d are recommended for patients receiving parenteral nutrition, but needs may be as high as 2-3 g/d in acutely ill patients.
    Language English
    Publishing date 2023-01-11
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2022.1083760
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Supplementierung von Vitamin C und D bei kritisch Kranken.

    Hill, Aileen / Starchl, Christina / Dresen, Ellen / Stoppe, Christian / Amrein, Karin

    Medizinische Klinik, Intensivmedizin und Notfallmedizin

    2023  Volume 118, Issue 2, Page(s) 114–121

    Abstract: Micronutrient supplementation as part of the medical nutrition therapy for critically ill patients has received much attention in the past few years. Nevertheless, in clinical practice uncertainty remains about the optimal supplementation strategy, ... ...

    Title translation Vitamin C and D supplementation in critically ill patients.
    Abstract Micronutrient supplementation as part of the medical nutrition therapy for critically ill patients has received much attention in the past few years. Nevertheless, in clinical practice uncertainty remains about the optimal supplementation strategy, including which substance at which dosage should be administered at what time to specific groups of patients. Thus, the aim of this narrative review is to summarize the current evidence and recommendations for the micronutrients vitamin C and vitamin D. The physiological and pathophysiological roles of both vitamins are presented, recently published clinical trials are discussed, and the recommendations of the current guidelines are summarized. In addition, pragmatic tips for use in everyday clinical practice in the intensive care unit are given.
    MeSH term(s) Humans ; Ascorbic Acid/therapeutic use ; Critical Illness/therapy ; Vitamins/therapeutic use ; Vitamin A ; Dietary Supplements
    Chemical Substances Ascorbic Acid (PQ6CK8PD0R) ; Vitamins ; Vitamin A (11103-57-4)
    Language German
    Publishing date 2023-01-11
    Publishing country Germany
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 2636018-4
    ISSN 2193-6226 ; 1435-1420 ; 0723-5003 ; 2193-6218 ; 0175-3851
    ISSN (online) 2193-6226 ; 1435-1420
    ISSN 0723-5003 ; 2193-6218 ; 0175-3851
    DOI 10.1007/s00063-022-00986-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.120: Show issues Location:
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  8. Article: Vitamin D status in critical care: Contributor or marker of poor health?

    Amrein, Karin

    Lung India : official organ of Indian Chest Society

    2014  Volume 31, Issue 3, Page(s) 299–300

    Language English
    Publishing date 2014-07-13
    Publishing country India
    Document type Journal Article
    ZDB-ID 2410801-7
    ISSN 0974-598X ; 0970-2113
    ISSN (online) 0974-598X
    ISSN 0970-2113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Baclofen-Induced Coma Reversible by Dialysis in a Patient Affected by Acute Kidney Injury

    Oliver Malle / Tadeja Urbanic Purkart / Karin Amrein

    Clinical Management Issues, Vol 16, Iss

    2022  Volume 1

    Abstract: Baclofen is commonly used to treat muscular spasticity and other conditions such as pain, alcohol withdrawal, and myoclonus. It is contraindicated in chronic kidney disease. As it is eliminated predominantly by the kidneys, acute kidney injury can lead ... ...

    Abstract Baclofen is commonly used to treat muscular spasticity and other conditions such as pain, alcohol withdrawal, and myoclonus. It is contraindicated in chronic kidney disease. As it is eliminated predominantly by the kidneys, acute kidney injury can lead to acute baclofen overdose with central nervous system affection due to drug accumulation. Currently, there is no consensus about the treatment of baclofen intoxication. A 67-year-old woman was admitted with altered mental status and vomiting. Initially, she was unresponsive/lethargic and kept the intermittent ability of nonverbal communication gradually sliding into a comatose state with apneas. Initial neurologic and radiologic examinations ruled out a structural lesion of the central nervous system. Laboratory data showed acute kidney injury and suspected urinary tract infection with extremely high inflammation parameters. The patient had a history of multiple sclerosis and received daily oral baclofen. Baclofen-induced coma secondary to baclofen overdose caused by renal insufficiency was suspected and renal dialysis started within 24 hours. Cystoscopy and implantation of a ureteric stent were necessary because of obstructive nephropathy. During hemodialysis, the patient’s mental status steadily improved. The patient woke up and was oriented and cooperative. Both clinical and laboratory data were widely normalized within days. Diagnosis of baclofen overdose can be challenging, but adequate supportive therapy, including hemodialysis, should be considered to reduce the length of comatose state and the risk of aspiration pneumonia.
    Keywords coma ; baclofen ; acute kidney injury ; dialysis ; Medicine (General) ; R5-920
    Subject code 616
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher SEEd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  10. Article ; Online: Micronutrients in Sepsis and COVID-19: A Narrative Review on What We Have Learned and What We Want to Know in Future Trials.

    Rossetti, Matteo / Martucci, Gennaro / Starchl, Christina / Amrein, Karin

    Medicina (Kaunas, Lithuania)

    2021  Volume 57, Issue 5

    Abstract: Sepsis remains the leading cause of mortality in hospitalized patients, contributing to 1 in every 2-3 deaths. From a pathophysiological view, in the recent definition, sepsis has been defined as the result of a complex interaction between host response ... ...

    Abstract Sepsis remains the leading cause of mortality in hospitalized patients, contributing to 1 in every 2-3 deaths. From a pathophysiological view, in the recent definition, sepsis has been defined as the result of a complex interaction between host response and the infecting organism, resulting in life-threatening organ dysfunction, depending on microcirculatory derangement, cellular hypoxia/dysoxia driven by hypotension and, potentially, death. The high energy expenditure driven by a high metabolic state induced by the host response may rapidly lead to micronutrient depletion. This deficiency can result in alterations in normal energy homeostasis, free radical damage, and immune system derangement. In critically ill patients, micronutrients are still relegated to an ancillary role in the whole treatment, and always put in a second-line place or, frequently, neglected. Only some micronutrients have attracted the attention of a wider audience, and some trials, even large ones, have tested their use, with controversial results. The present review will address this topic, including the recent advancement in the study of vitamin D and protocols based on vitamin C and other micronutrients, to explore an update in the setting of sepsis, gain some new insights applicable to COVID-19 patients, and to contribute to a pathophysiological definition of the potential role of micronutrients that will be helpful in future dedicated trials.
    MeSH term(s) COVID-19 ; Humans ; Microcirculation ; Micronutrients ; SARS-CoV-2 ; Sepsis
    Chemical Substances Micronutrients
    Language English
    Publishing date 2021-04-26
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina57050419
    Database MEDical Literature Analysis and Retrieval System OnLINE

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