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  1. Article: Topical Calcineurin Inhibitors in the Management of Chronic Pruritus in Older Adults: A Research Letter.

    Tully, Janell / Butler, Daniel C

    Journal of drugs in dermatology : JDD

    2024  Volume 23, Issue 2, Page(s) e70–e72

    Abstract: ... itch. J Drugs Dermatol. 2024;23(2): doi:10.36849/JDD.7190e. ...

    Abstract In this study, we aimed to analyze the literature to date on the utilization of topical calcineurin inhibitors in the management of pruritus among older adults, ages 65 and older. The 16 studies included in the final analysis demonstrated that topical calcineurin inhibitors are well tolerated across ages and are effective in treating a wide variety of chronic pruritic conditions. Collectively, these findings support that topical calcineurin inhibitors should be considered a safe, plausible option for managing age-associated itch. J Drugs Dermatol. 2024;23(2): doi:10.36849/JDD.7190e.
    MeSH term(s) Humans ; Aged ; Calcineurin Inhibitors/adverse effects ; Pruritus/diagnosis ; Pruritus/drug therapy
    Chemical Substances Calcineurin Inhibitors
    Language English
    Publishing date 2024-02-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2145090-0
    ISSN 1545-9616
    ISSN 1545-9616
    DOI 10.36849/JDD.7190
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    Zs.A 5931: Show issues Location:
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  2. Article ; Online: Potential Distribution of the Biocontrol Agent Toxorhynchites rutilus By 2070.

    Marshall, Daniel S / Butler, Christopher J

    Journal of the American Mosquito Control Association

    2021  Volume 36, Issue 3, Page(s) 131–138

    Abstract: Climate change projections indicate that mosquito distributions will expand to include new areas of North America, increasing human exposure to mosquito-borne disease. Controlling these vectors is imperative, as mosquito-borne disease incidence will rise ...

    Abstract Climate change projections indicate that mosquito distributions will expand to include new areas of North America, increasing human exposure to mosquito-borne disease. Controlling these vectors is imperative, as mosquito-borne disease incidence will rise in response to expansion of mosquito range and increased seasonality. One means of mosquito control used in the USA is the biocontrol agent, Toxorhynchites rutilus. Climate change will open new habitats for its use by vector control organizations, but the extent of this change in habitat is currently unknown. We used a maximum entropy approach to create species distribution models for Tx. rutilus under 4 climate change scenarios by 2070. Mean temperature of warmest quarter (22.6°C to 29.1°C), annual precipitation (1,025.15 mm to 1,529.40 mm), and precipitation seasonality (≤17.86) are the most important bioclimatic variables for suitable habitat. The center of current possible habitat distribution of Tx. rutilus is in central Tennessee. Depending upon the scenario, we expect centroids to shift north-northeast by 97.68 km to 280.16 km by 2070. The extreme change in area of greater than 50% suitable habitat probability is 141.14% with 99.44% area retained. Our models indicate limited change in current habitat as well as creation of new habitat. These results are promising for North American mosquito control programs for the continued and potential combat of vector mosquitoes using Tx. rutilus.
    MeSH term(s) Animal Distribution ; Animals ; Biological Control Agents ; Climate Change ; Culicidae/physiology ; Mosquito Control ; United States
    Chemical Substances Biological Control Agents
    Language English
    Publishing date 2021-02-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632618-3
    ISSN 1943-6270 ; 8756-971X
    ISSN (online) 1943-6270
    ISSN 8756-971X
    DOI 10.2987/8756-971X-36.3.131
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  3. Article ; Online: Integrating lesbian, gay, bisexual, transgender, and queer (LGBTQ) competency into the dental school curriculum.

    Salter, Reginald O / Barham, LaToya / Young, Daniel L / McIntosh, Crystal / Butler, Craig J

    Journal of dental education

    2024  

    Abstract: Background: Decreasing healthcare disparities in marginalized communities requires healthcare providers who understand and appreciate social, economic, and cultural backgrounds. This includes care and education focused on individuals who identify as ... ...

    Abstract Background: Decreasing healthcare disparities in marginalized communities requires healthcare providers who understand and appreciate social, economic, and cultural backgrounds. This includes care and education focused on individuals who identify as lesbian, gay, bisexual, transgender, or queer (LGBTQ).
    Methods: This study examined dental students' and residents' self-reported clinical preparedness, prejudicial attitudes (implicit and explicit), and knowledge of health disparities that exist in the LGBTQ community using the Lesbian, Gay, Bisexual, Transgender Development of Clinical Skills Scale (LGBT-DOCSS) prior to and after the presentation of an LGBTQ competency course.
    Results: A total of 178 dental students at a private US dental school ranging from D1 to first-year postdoctoral residency participated in the course and completed both pre-course survey and post-course survey. Sixty-seven percent of the students reported having formal training in LGBTQ competency prior to completing the pre-training survey. The results of the LGBT-DOCSS in this population following intervention training revealed an increased feeling of clinical preparedness in treating LGBTQ patients, decreased bias toward LGBTQ, and increased knowledge of health disparities in the LGBTQ community. A more significant percentage of male respondents self-reported prejudicial beliefs. Knowledge of LGBTQ health issues increased significantly among pre-clinical students.
    Conclusion: Introducing an early intervention LGBTQ competency course in the dental curriculum is an effective method of improving students' awareness and self-confidence in working with LGBTQ patients while decreasing biases that may have existed prior to a training course.
    Language English
    Publishing date 2024-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 410579-5
    ISSN 1930-7837 ; 0022-0337
    ISSN (online) 1930-7837
    ISSN 0022-0337
    DOI 10.1002/jdd.13476
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  4. Article: Outcomes of Iliac Wing Fractures: A Systematic Review of the Literature.

    Cruz, Jacquelyn P / Cantrell, Colin K / Johnson, Daniel J / Gerlach, Erik B / Butler, Bennet A

    Journal of surgical orthopaedic advances

    2024  Volume 32, Issue 3, Page(s) 139–147

    Abstract: To review the literature on iliac wing fractures to assess outcomes of operative and nonoperative treatment. A search of PubMed, MEDLINE, and Cochrane Database of Systematic Reviews was performed. Articles reporting on iliac wing fractures without pelvic ...

    Abstract To review the literature on iliac wing fractures to assess outcomes of operative and nonoperative treatment. A search of PubMed, MEDLINE, and Cochrane Database of Systematic Reviews was performed. Articles reporting on iliac wing fractures without pelvic ring destabilization or intraarticular extension were included. Study information and patient data were collected, and a Methodological Index for Non-randomized Studies (MINORS) score was assigned to each article. In total, 19,363 articles were identified with 32 qualifying for inclusion. The articles included 131 patients with 133 fractures. The mean age was 43.6, and mean follow-up time was 41.9 months. Forty-eight (36%) fractures were treated operatively, and 85 (64%) were treated nonoperatively. Associated injuries included bowel injuries, other pelvic fractures, gunshot wounds, and arterial injuries. There is an absence of comparative studies between operative and nonoperative management of iliac wing fractures. Indications for operative management appear to depend on comminution, open fractures, and associated injuries. (Journal of Surgical Orthopaedic Advances 32(3):139-147, 2023).
    MeSH term(s) Adult ; Humans ; Databases, Factual ; Fractures, Open ; Orthopedics ; Wounds, Gunshot
    Language English
    Publishing date 2024-01-22
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 2189157-6
    ISSN 2158-3811 ; 1548-825X ; 1059-1052
    ISSN (online) 2158-3811
    ISSN 1548-825X ; 1059-1052
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  5. Article ; Online: BASHH feedback from the 2023 IUSTI-Europe conference in Malta.

    Richardson, Daniel / Butler, Michael / Bull Olozabal, Oliver / Gupta, Nadi / Naser, Fahad / Sultan, Binta / Caswell, Rachel J

    Sexually transmitted infections

    2024  Volume 100, Issue 3, Page(s) 197–198

    MeSH term(s) Humans ; Malta/epidemiology ; Feedback ; Europe/epidemiology
    Language English
    Publishing date 2024-04-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 1420303-0
    ISSN 1472-3263 ; 1368-4973
    ISSN (online) 1472-3263
    ISSN 1368-4973
    DOI 10.1136/sextrans-2024-056111
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  6. Article ; Online: Large-scale capture of hidden fluorescent labels for training generalizable markerless motion capture models.

    Butler, Daniel J / Keim, Alexander P / Ray, Shantanu / Azim, Eiman

    Nature communications

    2023  Volume 14, Issue 1, Page(s) 5866

    Abstract: Deep learning-based markerless tracking has revolutionized studies of animal behavior. Yet the generalizability of trained models tends to be limited, as new training data typically needs to be generated manually for each setup or visual environment. ... ...

    Abstract Deep learning-based markerless tracking has revolutionized studies of animal behavior. Yet the generalizability of trained models tends to be limited, as new training data typically needs to be generated manually for each setup or visual environment. With each model trained from scratch, researchers track distinct landmarks and analyze the resulting kinematic data in idiosyncratic ways. Moreover, due to inherent limitations in manual annotation, only a sparse set of landmarks are typically labeled. To address these issues, we developed an approach, which we term GlowTrack, for generating orders of magnitude more training data, enabling models that generalize across experimental contexts. We describe: a) a high-throughput approach for producing hidden labels using fluorescent markers; b) a multi-camera, multi-light setup for simulating diverse visual conditions; and c) a technique for labeling many landmarks in parallel, enabling dense tracking. These advances lay a foundation for standardized behavioral pipelines and more complete scrutiny of movement.
    MeSH term(s) Motion Capture ; Movement ; Biomechanical Phenomena ; Motion
    Language English
    Publishing date 2023-09-26
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-41565-3
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  7. Article ; Online: Cooling Research Fever in Dermatology-The Role of Community Service-Reply.

    Gandelman, Jocelyn / Mathes, Erin / Butler, Daniel

    JAMA dermatology

    2024  Volume 160, Issue 4, Page(s) 478

    MeSH term(s) Humans ; Dermatology ; Fever
    Language English
    Publishing date 2024-02-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701761-8
    ISSN 2168-6084 ; 2168-6068
    ISSN (online) 2168-6084
    ISSN 2168-6068
    DOI 10.1001/jamadermatol.2023.6092
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  8. Article: Single-port transoral robotic surgery for a rare tonsil mass.

    Allen, David Z / Gorelik, Daniel / Butler, Edward B / Zhang, Jun / Kain, Joshua J

    Journal of surgical case reports

    2023  Volume 2023, Issue 4, Page(s) rjad197

    Abstract: Squamous cell carcinoma predominates as the most common malignant lesion of the oropharynx with human papilloma virus-associated disease now predominant over tobacco-related oropharynx cancer. Other rare malignant pathologies can manifest as visible ... ...

    Abstract Squamous cell carcinoma predominates as the most common malignant lesion of the oropharynx with human papilloma virus-associated disease now predominant over tobacco-related oropharynx cancer. Other rare malignant pathologies can manifest as visible neoplasms in these anatomic sites with varying degrees of symptoms such as dysphagia, odynophagia, otalgia, aspiration, hemorrhage, weight loss and dyspnea. We present a case of a rarely encountered primary oropharyngeal sarcoma managed by single-port transoral robotic resection and a selective cervical lymph node dissection followed by adjuvant radiotherapy.
    Language English
    Publishing date 2023-04-19
    Publishing country England
    Document type Case Reports
    ZDB-ID 2580919-2
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjad197
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  9. Article ; Online: Large-scale capture of hidden fluorescent labels for training generalizable markerless motion capture models

    Daniel J. Butler / Alexander P. Keim / Shantanu Ray / Eiman Azim

    Nature Communications, Vol 14, Iss 1, Pp 1-

    2023  Volume 16

    Abstract: Abstract Deep learning-based markerless tracking has revolutionized studies of animal behavior. Yet the generalizability of trained models tends to be limited, as new training data typically needs to be generated manually for each setup or visual ... ...

    Abstract Abstract Deep learning-based markerless tracking has revolutionized studies of animal behavior. Yet the generalizability of trained models tends to be limited, as new training data typically needs to be generated manually for each setup or visual environment. With each model trained from scratch, researchers track distinct landmarks and analyze the resulting kinematic data in idiosyncratic ways. Moreover, due to inherent limitations in manual annotation, only a sparse set of landmarks are typically labeled. To address these issues, we developed an approach, which we term GlowTrack, for generating orders of magnitude more training data, enabling models that generalize across experimental contexts. We describe: a) a high-throughput approach for producing hidden labels using fluorescent markers; b) a multi-camera, multi-light setup for simulating diverse visual conditions; and c) a technique for labeling many landmarks in parallel, enabling dense tracking. These advances lay a foundation for standardized behavioral pipelines and more complete scrutiny of movement.
    Keywords Science ; Q
    Subject code 006
    Language English
    Publishing date 2023-09-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: The spectrum of post-myocardial infarction care: From acute ischemia to heart failure.

    Akhtar, Khawaja Hassan / Khan, Muhammad Shahzeb / Baron, Suzanne J / Zieroth, Shelley / Estep, Jerry / Burkhoff, Daniel / Butler, Javed / Fudim, Marat

    Progress in cardiovascular diseases

    2024  Volume 82, Page(s) 15–25

    Abstract: Heart failure (HF) is the leading cause of mortality in patients with acute myocardial infarction (AMI), with incidence ranging from 14% to 36% in patients admitted due to AMI. HF post-MI develops due to complex inter-play between macrovascular ... ...

    Abstract Heart failure (HF) is the leading cause of mortality in patients with acute myocardial infarction (AMI), with incidence ranging from 14% to 36% in patients admitted due to AMI. HF post-MI develops due to complex inter-play between macrovascular obstruction, microvascular dysfunction, myocardial stunning and remodeling, inflammation, and neuro-hormonal activation. Cardiogenic shock is an extreme presentation of HF post-MI and is associated with a high mortality. Early revascularization is the only therapy shown to improve survival in patients with cardiogenic shock. Treatment of HF post-MI requires prompt recognition and timely introduction of guideline-directed therapies to improve mortality and morbidity. This article aims to provide an up-to-date review on the incidence and pathogenesis of HF post-MI, current strategies to prevent and treat onset of HF post-MI, promising therapeutic strategies, and knowledge gaps in the field.
    MeSH term(s) Humans ; Shock, Cardiogenic/diagnosis ; Shock, Cardiogenic/etiology ; Shock, Cardiogenic/therapy ; Myocardial Infarction/diagnosis ; Myocardial Infarction/therapy ; Myocardial Infarction/complications ; Heart Failure/diagnosis ; Heart Failure/epidemiology ; Heart Failure/therapy
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 209312-1
    ISSN 1873-1740 ; 1532-8643 ; 0033-0620
    ISSN (online) 1873-1740 ; 1532-8643
    ISSN 0033-0620
    DOI 10.1016/j.pcad.2024.01.017
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