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  1. Article ; Online: Moving forward for incidental pulmonary embolism in cancer patients.

    Dos Santos Fernandes, Caio Julio Cesar / Couturaud, Francis

    The European respiratory journal

    2021  Volume 58, Issue 1

    MeSH term(s) Humans ; Neoplasms/complications ; Pulmonary Embolism/diagnosis
    Language English
    Publishing date 2021-07-01
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.04630-2020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Should all COVID-19 patients be approached in the same way?

    Fernandes, Caio Julio Cesar Dos Santos

    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

    2020  Volume 46, Issue 4, Page(s) e20200218

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/therapy ; Humans ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/therapy ; SARS-CoV-2
    Keywords covid19
    Language Portuguese
    Publishing date 2020-07-20
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2223157-2
    ISSN 1806-3756 ; 1806-3713
    ISSN (online) 1806-3756
    ISSN 1806-3713
    DOI 10.36416/1806-3756/e20200218
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: Should all COVID-19 patients be approached in the same way?

    Fernandes, Caio Julio Cesar dos Santos

    Jornal Brasileiro de Pneumologia v.46 n.4 2020

    2020  

    Keywords covid19
    Language English
    Publishing date 2020-01-01
    Publisher Sociedade Brasileira de Pneumologia e Tisiologia
    Publishing country br
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Should all COVID-19 patients be approached in the same way?

    Fernandes, Caio Julio Cesar Dos Santos

    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #663569
    Database COVID19

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  5. Article ; Online: Evolution in the management of non-small cell lung cancer in Brazil.

    Fernandes, Caio Júlio Cesar Dos Santos

    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

    2017  Volume 43, Issue 6, Page(s) 403–404

    MeSH term(s) Adenocarcinoma ; Brazil ; Carcinoma, Non-Small-Cell Lung ; Humans ; Lung Neoplasms ; Retrospective Studies
    Language Portuguese
    Publishing date 2017-01-13
    Publishing country Brazil
    Document type Editorial ; Comment
    ZDB-ID 2223157-2
    ISSN 1806-3756 ; 1806-3713
    ISSN (online) 1806-3756
    ISSN 1806-3713
    DOI 10.1590/S1806-37562017000060002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Loss of response to calcium channel blockers after long-term follow-up treatment in patients with idiopathic pulmonary arterial hypertension.

    Piloto, Bruna / Fernandes, Caio Julio Cesar Dos Santos / Jardim, Carlos / Castro, Marcela / Alves-Jr, Jose Leonidas / Souza, Rogerio

    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

    2023  Volume 49, Issue 3, Page(s) e20220337

    Abstract: Idiopathic pulmonary arterial hypertension (PAH) patients with a positive response to acute vasodilator challenge and a clinical response to calcium channel blockers (CCBs) for at least one year are traditionally designated true responders. Nevertheless, ...

    Abstract Idiopathic pulmonary arterial hypertension (PAH) patients with a positive response to acute vasodilator challenge and a clinical response to calcium channel blockers (CCBs) for at least one year are traditionally designated true responders. Nevertheless, little is known about a sustained response to CCBs over longer periods of time. We evaluated the loss of response to CCBs after long-term treatment in a cohort of idiopathic PAH patients previously classified as being true responders. Our data suggest that idiopathic PAH patients can lose clinical response to CCBs even after one year of clinical stability, reinforcing the need for constant multidimensional reevaluation to assess the need for targeted PAH therapies and to classify these patients correctly.
    MeSH term(s) Humans ; Calcium Channel Blockers/therapeutic use ; Familial Primary Pulmonary Hypertension/drug therapy ; Familial Primary Pulmonary Hypertension/chemically induced ; Follow-Up Studies ; Hypertension, Pulmonary/drug therapy ; Vasodilator Agents/therapeutic use
    Chemical Substances Calcium Channel Blockers ; Vasodilator Agents
    Language Portuguese
    Publishing date 2023-05-01
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2223157-2
    ISSN 1806-3756 ; 1806-3713
    ISSN (online) 1806-3756
    ISSN 1806-3713
    DOI 10.36416/1806-3756/e20220337
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Pulmonary Hypertension in General Cardiology Practice.

    Calderaro, Daniela / Alves Junior, José Leonidas / Fernandes, Caio Júlio César Dos Santos / Souza, Rogério

    Arquivos brasileiros de cardiologia

    2019  Volume 113, Issue 3, Page(s) 419–428

    Abstract: The finding of pulmonary hypertension (PH) by echocardiography is common and of concern. However, echocardiography is just a suggestive and non-diagnostic assessment of PH. When direct involvement of pulmonary circulation is suspected, invasive ... ...

    Abstract The finding of pulmonary hypertension (PH) by echocardiography is common and of concern. However, echocardiography is just a suggestive and non-diagnostic assessment of PH. When direct involvement of pulmonary circulation is suspected, invasive hemodynamic monitoring is recommended to establish the diagnosis. This assessent provides, in addition to the diagnostic confirmation, the correct identification of the vascular territory predominantly involved (arterial pulmonary or postcapillary). Treatment with specific medication for PH (phosphodiesterase type 5 inhibitors, endothelin receptor antagonists and prostacyclin analogues) has been proven effective in patients with pulmonary arterial hypertension, but its use in patients with PH due to left heart disease can even be damaging. In this review, we discuss the diagnosis criteria, how etiological investigation should be carried out, the clinical classification and, finally, the therapeutic recommendations for PH.
    MeSH term(s) Echocardiography ; Heart Diseases/complications ; Humans ; Hypertension, Pulmonary/diagnostic imaging ; Hypertension, Pulmonary/etiology ; Hypertension, Pulmonary/physiopathology ; Hypertension, Pulmonary/therapy ; Pulmonary Circulation ; Pulmonary Disease, Chronic Obstructive/complications ; Risk Assessment
    Language Portuguese
    Publishing date 2019-10-10
    Publishing country Brazil
    Document type Journal Article ; Review
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.5935/abc.20190188
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Survival of connective tissue disease associated pulmonary arterial hypertension.

    Luppino Assad, Ana Paula / Gavilanes Oleas, Francisca / Alves, Jose Leonidas / Dos Santos Fernandes, Caio Julio Cesar / Sampaio-Barros, Percival Degrava / Souza, Rogerio

    Clinical and experimental rheumatology

    2018  Volume 36 Suppl 113, Issue 4, Page(s) 186

    MeSH term(s) Adult ; Age Factors ; Aged ; Arterial Pressure ; Brazil/epidemiology ; Connective Tissue Diseases/diagnosis ; Connective Tissue Diseases/mortality ; Connective Tissue Diseases/physiopathology ; Female ; Humans ; Hypertension, Pulmonary/diagnosis ; Hypertension, Pulmonary/mortality ; Hypertension, Pulmonary/physiopathology ; Male ; Middle Aged ; Pulmonary Artery/physiopathology ; Registries ; Risk Assessment ; Risk Factors ; Survival Rate ; Time Factors
    Language English
    Publishing date 2018-04-19
    Publishing country Italy
    Document type Letter
    ZDB-ID 605886-3
    ISSN 1593-098X ; 0392-856X
    ISSN (online) 1593-098X
    ISSN 0392-856X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Association between pulmonary artery to aorta diameter ratio with pulmonary hypertension and outcomes in diffuse cystic lung diseases.

    Baldi, Bruno Guedes / Fernandes, Caio Júlio César Dos Santos / Heiden, Gláucia Itamaro / Freitas, Carolina Salim Gonçalves / Sobral, Juliana Barbosa / Kairalla, Ronaldo Adib / Carvalho, Carlos Roberto Ribeiro / Souza, Rogério

    Medicine

    2021  Volume 100, Issue 25, Page(s) e26483

    Abstract: Abstract: To investigate the importance of pulmonary vascular measurements on computed tomography (CT) in predicting pulmonary hypertension (PH) and worse outcomes in diffuse cystic lung diseases (DCLDs).We conducted a cross-sectional study of patients ... ...

    Abstract Abstract: To investigate the importance of pulmonary vascular measurements on computed tomography (CT) in predicting pulmonary hypertension (PH) and worse outcomes in diffuse cystic lung diseases (DCLDs).We conducted a cross-sectional study of patients with DCLDs. Patients underwent pulmonary function tests, a six-minute walk test (6MWT), chest CT, transthoracic echocardiography, and right heart catheterization. Pulmonary artery (PA) diameter and PA-ascending aorta ratio (PA-Ao ratio) were obtained from CT. Mean pulmonary artery pressure (mPAP) from right heart catheterization was correlated with tomographic, functional, and echocardiographic variables. The association between the PA-Ao ratio with outcomes was determined by Kaplan-Meier curves.Thirty-four patients were included (18 with pulmonary Langerhans cell histiocytosis and 16 with lymphangioleiomyomatosis, mean age 46 ± 9 years). Forced expiratory volume in the first second and lung diffusing capacity for carbon monoxide were 47 ± 20% and 38 ± 21% predicted, respectively. PA diameter and PA-Ao ratio were 29 ± 6 mm and 0.95 ± 0.24, respectively. PA-Ao ratio > 1 occurred in 38.2% of patients. PA-Ao ratio was a good predictor of PH. mPAP correlated best with PA-Ao ratio, PA diameter, oxygen desaturation during six-minute walk test, and echocardiographic variables. Patients with PA-Ao ratio > 1 had greater mPAP, and a higher risk of death or lung transplantation (log-rank, P < .001) than those with PA-Ao ratio ≤ 1.The PA-Ao ratio measured on CT scan has a potential role as a non-invasive tool to predict the presence of PH and as a prognostic parameter in patients with DCLDs.
    MeSH term(s) Adult ; Aorta/diagnostic imaging ; Aorta/pathology ; Cross-Sectional Studies ; Echocardiography ; Female ; Humans ; Hypertension, Pulmonary/diagnosis ; Hypertension, Pulmonary/etiology ; Lung/blood supply ; Lung/diagnostic imaging ; Lung/pathology ; Lung Diseases/complications ; Lung Diseases/mortality ; Lung Diseases/pathology ; Lung Diseases/surgery ; Lung Transplantation/statistics & numerical data ; Male ; Middle Aged ; Predictive Value of Tests ; Prognosis ; Pulmonary Artery/diagnostic imaging ; Pulmonary Artery/pathology ; ROC Curve ; Risk Assessment/statistics & numerical data ; Tomography, X-Ray Computed ; Walk Test
    Language English
    Publishing date 2021-07-07
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000026483
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Brazilian Thoracic Society recommendations for the diagnosis and treatment of chronic thromboembolic pulmonary hypertension.

    Fernandes, Caio Julio Cesar Dos Santos / Ota-Arakaki, Jaquelina Sonoe / Campos, Frederico Thadeu Assis Figueiredo / Correa, Ricardo de Amorim / Gazzana, Marcelo Basso / Jardim, Carlos Vianna Poyares / Jatene, Fábio Biscegli / Alves Junior, Jose Leonidas / Ramos, Roberta Pulcheri / Tannus, Daniela / Teles, Carlos / Terra Filho, Mario / Waetge, Daniel / Souza, Rogerio

    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

    2022  Volume 46, Issue 4, Page(s) e20200204

    Abstract: Chronic thromboembolic pulmonary hypertension (CTEPH) is a serious and debilitating disease caused by occlusion of the pulmonary arterial bed by hematic emboli and by the resulting fibrous material. Such occlusion increases vascular resistance and, ... ...

    Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a serious and debilitating disease caused by occlusion of the pulmonary arterial bed by hematic emboli and by the resulting fibrous material. Such occlusion increases vascular resistance and, consequently, the pressure in the region of the pulmonary artery, which is the definition of pulmonary hypertension. The increased load imposed on the right ventricle leads to its progressive dysfunction and, finally, to death. However, CTEPH has a highly significant feature that distinguishes it from other forms of pulmonary hypertension: the fact that it can be cured through treatment with pulmonary thromboendarterectomy. Therefore, the primary objective of the management of CTEPH should be the assessment of patient fitness for surgery at a referral center, given that not all patients are good candidates. For the patients who are not good candidates for pulmonary thromboendarterectomy, the viable therapeutic alternatives include pulmonary artery angioplasty and pharmacological treatment. In these recommendations, the pathophysiological bases for the onset of CTEPH, such as acute pulmonary embolism and the clinical condition of the patient, will be discussed, as will the diagnostic algorithm to be followed and the therapeutic alternatives currently available.
    MeSH term(s) Brazil ; Chronic Disease ; Endarterectomy/adverse effects ; Endarterectomy/methods ; Humans ; Hypertension, Pulmonary/diagnosis ; Hypertension, Pulmonary/etiology ; Hypertension, Pulmonary/therapy ; Pulmonary Artery/surgery ; Pulmonary Embolism/complications ; Pulmonary Embolism/diagnosis ; Pulmonary Embolism/therapy
    Language Portuguese
    Publishing date 2022-06-24
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2223157-2
    ISSN 1806-3756 ; 1806-3713
    ISSN (online) 1806-3756
    ISSN 1806-3713
    DOI 10.36416/1806-3756/e20200204
    Database MEDical Literature Analysis and Retrieval System OnLINE

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