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  1. Article ; Online: NLRP12

    Ghosh, Kanjaksha

    Annals of the rheumatic diseases

    2019  Volume 80, Issue 9, Page(s) e152

    MeSH term(s) Exome ; Humans ; India ; Intracellular Signaling Peptides and Proteins ; Mutation ; Whole Exome Sequencing
    Chemical Substances Intracellular Signaling Peptides and Proteins ; NLRP12 protein, human
    Language English
    Publishing date 2019-09-20
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 7090-7
    ISSN 1468-2060 ; 0003-4967
    ISSN (online) 1468-2060
    ISSN 0003-4967
    DOI 10.1136/annrheumdis-2019-216270
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    Uh III Zs.114: Show issues Location:
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  2. Article ; Online: Confirmatory Assay for Laboratory Diagnosis of Malaria Using Molecular Approach.

    Patel, Parizad / Mishra, Kanchan Kumar / Ghosh, Kanjaksha

    Acta parasitologica

    2024  Volume 69, Issue 1, Page(s) 1000–1004

    Abstract: Background: Prompt malarial treatment and surveillance is crucial for accurate diagnosis of Plasmodium Sp. Gold standard microscopic examination has been widely applied for diagnosis of malaria in most part of the endemic areas. But in case of ... ...

    Abstract Background: Prompt malarial treatment and surveillance is crucial for accurate diagnosis of Plasmodium Sp. Gold standard microscopic examination has been widely applied for diagnosis of malaria in most part of the endemic areas. But in case of submicroscopic and asymptomatic microscopic diagnosis is questioned. The study aims to develop a simple, cost effective & robust nucleic acid amplification technique for the detection of malaria parasite.
    Methods: Study population included 50 clinically diagnosed positive malaria patient samples from various pathological laboratories. Microscopy by preparing thick film was carried out of every sample for primary screening in the available facility of Surat Raktadan Kendra & Research Centre- Blood Bank. The conventional PCR (Polymerase Chain Reaction) was applied for genus-specific amplification targeting the 18 S rRNA gene of Plasmodium. Agarose gel electrophoresis was used to separate and analyze the amplified PCR product using 2% Agarose gel.
    Results and conclusion: The study shows that nested PCR not only detected all microscopic positive samples, but also detected submicroscopic infections that were missed or misread by microscopy. Hence, the sensitivity of molecular based detection technique is proved to be more compared to microscopic examination.
    MeSH term(s) Humans ; Malaria/diagnosis ; Malaria/parasitology ; Polymerase Chain Reaction/methods ; Sensitivity and Specificity ; RNA, Ribosomal, 18S/genetics ; Plasmodium/genetics ; Plasmodium/isolation & purification ; Plasmodium/classification ; Molecular Diagnostic Techniques/methods ; Nucleic Acid Amplification Techniques/methods ; Microscopy/methods ; DNA, Protozoan/genetics
    Chemical Substances RNA, Ribosomal, 18S ; DNA, Protozoan
    Language English
    Publishing date 2024-03-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1132735-2
    ISSN 1896-1851 ; 0065-1478 ; 1230-2821
    ISSN (online) 1896-1851
    ISSN 0065-1478 ; 1230-2821
    DOI 10.1007/s11686-024-00831-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Increased Mortality in Male Recipients of Red Cells from ever Pregnant Female Donors: mHAGs on Red Cells to Blame?

    Ghosh, Kanjaksha

    Mediterranean journal of hematology and infectious diseases

    2018  Volume 10, Issue 1, Page(s) e2018009

    Language English
    Publishing date 2018-01-01
    Publishing country Italy
    Document type Journal Article ; Comment
    ZDB-ID 2674750-9
    ISSN 2035-3006
    ISSN 2035-3006
    DOI 10.4084/MJHID.2018.009
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  4. Article: Violence against doctors: A wake-up call.

    Ghosh, Kanjaksha

    The Indian journal of medical research

    2018  Volume 148, Issue 2, Page(s) 130–133

    MeSH term(s) Health Personnel/psychology ; Humans ; Physician-Patient Relations ; Physicians/psychology ; Violence/psychology
    Language English
    Publishing date 2018-10-31
    Publishing country India
    Document type Journal Article
    ZDB-ID 390883-5
    ISSN 0971-5916 ; 0019-5340
    ISSN 0971-5916 ; 0019-5340
    DOI 10.4103/ijmr.IJMR_1299_17
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  5. Article: Why we don't get doctors for rural medical service in India?

    Ghosh, Kanjaksha

    The National medical journal of India

    2018  Volume 31, Issue 1, Page(s) 44–46

    MeSH term(s) Career Choice ; Humans ; India ; Physicians ; Rural Health Services ; Schools, Medical
    Language English
    Publishing date 2018-10-19
    Publishing country India
    Document type Journal Article
    ZDB-ID 645116-0
    ISSN 0970-258X
    ISSN 0970-258X
    DOI 10.4103/0970-258X.243416
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  6. Article ; Online: Violence against doctors: A pandemic in the making.

    Ghosh, Kanjaksha

    European journal of internal medicine

    2018  Volume 50, Page(s) e9–e10

    MeSH term(s) Humans ; Physicians/statistics & numerical data ; Workplace Violence/statistics & numerical data ; Workplace Violence/trends
    Language English
    Publishing date 2018-02-13
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2017.08.017
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  7. Article ; Online: Violence against doctors

    Kanjaksha Ghosh

    Indian Journal of Medical Research, Vol 148, Iss 2, Pp 130-

    A wake-up call

    2018  Volume 133

    Keywords Medicine ; R
    Language English
    Publishing date 2018-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: D-Dimer: an analyte with increasing application in Covid-19 infection.

    Ghosh, Kanjaksha / Ghosh, Kinjalka

    Expert review of hematology

    2022  Volume 15, Issue 3, Page(s) 243–251

    Abstract: Introduction: D- Dimer levels from peripheral blood are increasingly used to assess various pathological conditions. Initially, an area for hematologists, now this analyte is evaluated more extensively from many specialties of medicine. Covid-19 ... ...

    Abstract Introduction: D- Dimer levels from peripheral blood are increasingly used to assess various pathological conditions. Initially, an area for hematologists, now this analyte is evaluated more extensively from many specialties of medicine. Covid-19 infection has not only added a new dimension to D-Dimer level assessment in this disease but has also shed newer lights to the underlying pathophysiological mechanisms for its elevation in this disease.
    Areas covered: Innate variability in measuring D- Dimer levels, Impact of various techniques in measuring D- Dimer, nonavailability of uniform controls and standards, molecular heterogeneity of the product, how it is produced. Reasons for raised D- Dimer in covid-19 infection. D- Dimer in other pathological states. Articles with relevant key words from 1990 searched in PubMed were utilized for review.
    Expert opinion: : D-Dimer has important application in diagnosis, prognosis, management, and understanding various conditions. Its level can rise with increased coagulability of blood, sepsis, cytokine storm, snake bite, etc. Renal function, age influences its reference ranges. Units of measurement, its expression varies in different reports needing international standardization. In Covid-19 infection its levels correlate with stage of the disease, pathology, and complications.
    MeSH term(s) COVID-19/diagnosis ; Cytokine Release Syndrome/diagnosis ; Fibrin Fibrinogen Degradation Products/metabolism ; Humans ; Prognosis
    Chemical Substances Fibrin Fibrinogen Degradation Products ; fibrin fragment D
    Language English
    Publishing date 2022-03-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2516804-6
    ISSN 1747-4094 ; 1747-4086
    ISSN (online) 1747-4094
    ISSN 1747-4086
    DOI 10.1080/17474086.2022.2052040
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    Zs.A 6943: Show issues Location:
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  9. Article ; Online: Monoclonal antibodies used for the management of hemataological disorders.

    Ghosh, Kanjaksha / Ghosh, Kinjalka

    Expert review of hematology

    2022  Volume 15, Issue 5, Page(s) 443–455

    Abstract: Introduction: Monoclonal antibodies Ab (MoAb) are increasingly becoming part of therapeutic armamentarium for haematologists and haemato-oncologists. This review brings together commonly used antibodies in one place for brevity and novel understanding.!# ...

    Abstract Introduction: Monoclonal antibodies Ab (MoAb) are increasingly becoming part of therapeutic armamentarium for haematologists and haemato-oncologists. This review brings together commonly used antibodies in one place for brevity and novel understanding.
    Areas covered: Pubmed and Scopus databases were explored focusing on MoAb in clinical haematological practice. Emphasis was given to current review articles. The data base was searched from 1997 till present. 24 different antibodies, most of which are in use were discussed. Antibodies are used for diverse conditions i.e. malignant and benign haematological conditions, treatment at various phases of stem cell transplantation. These antibodies were used both alone or in combination with various chemotherapy, targeted small molecules or as immunoconjugates. Some of the side effect profiles of these antibodies were common and some were unique. Unusual infections or organ dysfunctions were noted. Improved function of antibodies by protein engineering is also advancing rapidly. Dosage, frequency and route of administration depended on the convenience and condition for which the antibody is used.
    Expert opinion: MoAbs are increasingly used in haematology practice either alone or in combination with other types of therapy for improved out come in various haematological conditions.
    MeSH term(s) Antibodies, Monoclonal ; Antineoplastic Agents, Immunological ; Humans ; Immunoconjugates ; Immunotherapy
    Chemical Substances Antibodies, Monoclonal ; Antineoplastic Agents, Immunological ; Immunoconjugates
    Language English
    Publishing date 2022-05-30
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2516804-6
    ISSN 1747-4094 ; 1747-4086
    ISSN (online) 1747-4094
    ISSN 1747-4086
    DOI 10.1080/17474086.2022.2073213
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  10. Article ; Online: Quest for Doctors in a Dodoland.

    Ghosh, Kanjaksha

    Indian pediatrics

    2017  Volume 54, Issue 11, Page(s) 975

    MeSH term(s) Humans ; India ; Occupational Health ; Physicians ; Violence
    Language English
    Publishing date 2017--15
    Publishing country India
    Document type Letter
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
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