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  1. Book: Non-malignant disorders of the blood in infants and children

    Buchanan, George R.

    (Hematology oncology clinics of North America ; 18,6)

    2004  

    Author's details guest ed. George R. Buchanan
    Series title Hematology oncology clinics of North America ; 18,6
    Hematology, oncology clinics of North America
    Collection Hematology, oncology clinics of North America
    Language English
    Size XIV S., S. 1215 - 1491 : graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT014252963
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Se 1077 -18,6- verfügbar in Königswinter Königswinter

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  2. Book: Pediatric hematology

    Buchanan, George R.

    (The pediatric clinics of North America ; 43,3)

    1996  

    Author's details George R. Buchanan, guest ed
    Series title The pediatric clinics of North America ; 43,3
    Collection
    Keywords Hematologic Diseases / in infancy & childhood ; Kind ; Hämatologie
    Subject Kindheit ; Kindesalter ; Kindschaft ; Kinder
    Language English
    Size XII S., S. 599 - 828 : Ill., graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT007219401
    Database Catalogue ZB MED Medicine, Health

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    Um IV Zs 147 -43,3- verfügbar in Königswinter Königswinter

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  3. Article ; Online: Disorders of Iron Metabolism: New Diagnostic and Treatment Approaches to Iron Deficiency.

    Powers, Jacquelyn M / Buchanan, George R

    Hematology/oncology clinics of North America

    2019  Volume 33, Issue 3, Page(s) 393–408

    Abstract: Iron deficiency anemia is the leading cause of anemia worldwide and affects many young children and adolescent girls in the United States. Its signs and symptoms are subtle despite significant clinical effects. Iron deficiency anemia is diagnosed ... ...

    Abstract Iron deficiency anemia is the leading cause of anemia worldwide and affects many young children and adolescent girls in the United States. Its signs and symptoms are subtle despite significant clinical effects. Iron deficiency anemia is diagnosed clinically by the presence of risk factors and microcytic anemia. Improvement following a trial of oral iron therapy is confirmative. An array of iron laboratory tests is available with variable indications. Clinical trial and iron absorption data support a shift to lower-dose oral iron therapy. Intravenous iron should be considered in children who fail oral iron or who have more complex disorders.
    MeSH term(s) Adolescent ; Anemia/diagnosis ; Anemia/metabolism ; Anemia/therapy ; Anemia, Iron-Deficiency/diagnosis ; Anemia, Iron-Deficiency/metabolism ; Anemia, Iron-Deficiency/therapy ; Child, Preschool ; Female ; Hepcidins/metabolism ; Humans ; Infant ; Iron/administration & dosage ; Iron/metabolism ; Iron/therapeutic use ; Male
    Chemical Substances Hepcidins ; Iron (E1UOL152H7)
    Language English
    Publishing date 2019-03-29
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 93115-9
    ISSN 1558-1977 ; 0889-8588
    ISSN (online) 1558-1977
    ISSN 0889-8588
    DOI 10.1016/j.hoc.2019.01.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Immune thrombocytopenia during childhood: new approaches to classification and management.

    Buchanan, George R

    The Journal of pediatrics

    2014  Volume 165, Issue 3, Page(s) 437–439

    MeSH term(s) Benzoates/therapeutic use ; Female ; Humans ; Hydrazines/therapeutic use ; Male ; Purpura, Thrombocytopenic, Idiopathic/drug therapy ; Pyrazoles/therapeutic use ; Receptors, Fc/therapeutic use ; Recombinant Fusion Proteins/therapeutic use ; Thrombopoietin/therapeutic use
    Chemical Substances Benzoates ; Hydrazines ; Pyrazoles ; Receptors, Fc ; Recombinant Fusion Proteins ; Thrombopoietin (9014-42-0) ; romiplostim (GN5XU2DXKV) ; eltrombopag (S56D65XJ9G)
    Language English
    Publishing date 2014-09
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2014.05.030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Paucity of clinical trials in iron deficiency: lessons learned from study of VLBW infants.

    Buchanan, George R

    Pediatrics

    2013  Volume 131, Issue 2, Page(s) e582–4

    MeSH term(s) Anemia, Iron-Deficiency/drug therapy ; Dietary Supplements ; Female ; Humans ; Infant Formula ; Infant, Premature, Diseases/drug therapy ; Infant, Very Low Birth Weight ; Iron, Dietary/administration & dosage ; Male ; Milk, Human ; Vitamins/administration & dosage
    Chemical Substances Iron, Dietary ; Vitamins
    Language English
    Publishing date 2013-02
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 207677-9
    ISSN 1098-4275 ; 0031-4005
    ISSN (online) 1098-4275
    ISSN 0031-4005
    DOI 10.1542/peds.2012-3365
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 357: Show issues

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  6. Article ; Online: "Packaging" of fetal hemoglobin in sickle cell anemia.

    Buchanan, George R

    Blood

    2013  Volume 123, Issue 4, Page(s) 464–465

    Abstract: In this issue of Blood, Steinberg et al describe the clinical importance of the distribution or "packaging" of fetal hemoglobin (HbF) within erythrocytes of persons with sickle cell anemia. ...

    Abstract In this issue of Blood, Steinberg et al describe the clinical importance of the distribution or "packaging" of fetal hemoglobin (HbF) within erythrocytes of persons with sickle cell anemia.
    MeSH term(s) Anemia, Sickle Cell/immunology ; Anemia, Sickle Cell/therapy ; Fetal Hemoglobin/immunology ; Humans
    Chemical Substances Fetal Hemoglobin (9034-63-3)
    Language English
    Publishing date 2013-12-14
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood-2013-11-539981
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 364: Show issues

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  7. Article ; Online: 50 years ago in the Journal of Pediatrics: familial idiopathic thrombocytopenic purpura.

    Buchanan, George R

    The Journal of pediatrics

    2013  Volume 162, Issue 4, Page(s) 704

    MeSH term(s) Blood Platelets/cytology ; Cell Size ; Family Health ; History, 20th Century ; Humans ; Infant, Newborn ; Male ; Pediatrics/history ; Platelet Count ; Purpura, Thrombocytopenic, Idiopathic/diagnosis ; Purpura, Thrombocytopenic, Idiopathic/surgery ; Siblings ; Splenectomy
    Language English
    Publishing date 2013-04
    Publishing country United States
    Document type Historical Article ; Journal Article
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2012.10.051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Potential for Improved Screening, Diagnosis, and Treatment for Iron Deficiency and Iron Deficiency Anemia in Young Children.

    Powers, Jacquelyn M / Buchanan, George R

    The Journal of pediatrics

    2017  Volume 188, Page(s) 8–10

    MeSH term(s) Anemia, Iron-Deficiency ; Child ; Child, Preschool ; Ferritins ; Humans ; Infant ; Iron ; Mass Screening
    Chemical Substances Ferritins (9007-73-2) ; Iron (E1UOL152H7)
    Language English
    Publishing date 2017-05-23
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2017.04.069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Understanding Older Adults' Experiences With Technologies for Health Self-management: Interview Study.

    Garcia Reyes, Elsy Paola / Kelly, Ryan / Buchanan, George / Waycott, Jenny

    JMIR aging

    2023  Volume 6, Page(s) e43197

    Abstract: Background: Many older adults now use technologies such as wearable devices and telehealth services to support their health and well-being while living independently at home. However, older adults vary in how they use these technologies, and there is a ... ...

    Abstract Background: Many older adults now use technologies such as wearable devices and telehealth services to support their health and well-being while living independently at home. However, older adults vary in how they use these technologies, and there is a lack of knowledge regarding the motivations that influence their acceptance and use of health-related technologies in home environments.
    Objective: This study aimed to understand the types of technologies that older adults use to support their health and the factors that motivate them to use their chosen technologies to support their health. In addition, we aimed to understand the factors that enable the effective use of technologies for health self-management and to identify the barriers that can negatively affect the adoption of technologies.
    Methods: A total of 22 older adults participated in semistructured interviews regarding their experiences of using technologies for health self-management. Interview transcripts were analyzed through an in-depth thematic analysis.
    Results: The interviews revealed that a range of technologies, such as videoconferencing software, fitness trackers, and other devices, were being used by older adults to support their health. Interviews showed that participants were motivated to use technologies to monitor health issues, to stay active and connected, and to record and change their behavior in the light of foreseen risks related to their future health status. Enablers that facilitated the effective use of technologies include social and organizational influence, convenient access to health care and safety provided by the technology, and easy setup and low cost of the technology. Barriers include information overload and a sense of futility about future health decline; telehealth being an inadequate substitute for in-person consultation; concerns about trust related to privacy and accuracy; and technologies being stigmatizing, uncomfortable to use, expensive, and unfamiliar.
    Conclusions: This study suggested that older adults were using a variety of technologies to prevent or prepare for future health decline, evidencing a resilient attitude toward health and aging. In addition, older adults were willing to continue using the technology when there was a perceived need. The enabler mentioned by most participants was the social and organizational influence that included health care staff, family, friends, and organizations. This analysis provides a better understanding of how older adults use technologies to support their health and can guide the provision of appropriate health technologies for them.
    Language English
    Publishing date 2023-03-21
    Publishing country Canada
    Document type Journal Article
    ISSN 2561-7605
    ISSN (online) 2561-7605
    DOI 10.2196/43197
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Safety, Efficacy, and Durability of Outcomes: Results from SECURE: A Single Arm, Multicenter, Prospective, Clinical Study on a Minimally Invasive Posterior Sacroiliac Fusion Allograft Implant.

    Calodney, Aaron / Azeem, Nomen / Buchanan, Patrick / Skaribas, Ioannis / Antony, Ajay / Kim, Christopher / Girardi, George / Vu, Chau / Bovinet, Christopher / Vogel, Rainer / Li, Sean / Jassal, Navdeep / Josephson, Youssef / Lubenow, Timothy / Lam, Christopher M / Deer, Timothy R

    Journal of pain research

    2024  Volume 17, Page(s) 1209–1222

    Abstract: Introduction: Research suggests that sacroiliac joint (SIJ) dysfunction is responsible for 15% to 30% of reported low back pain cases. Recently, there has been an increasing interest in SIJ fusion using minimally invasive surgery (MIS) due to safety. ... ...

    Abstract Introduction: Research suggests that sacroiliac joint (SIJ) dysfunction is responsible for 15% to 30% of reported low back pain cases. Recently, there has been an increasing interest in SIJ fusion using minimally invasive surgery (MIS) due to safety. Initially, devices designed for MIS were intended for lateral approaches. A minimally invasive sacroiliac fusion implant for use with a posterior approach has been developed and is regulated for clinical use under the regulatory framework required for human cells, tissues, or cellular or tissue-based products (HCT/Ps).
    Methods: A multi-center, prospective, single-arm study was launched after initial studies provided preliminary data to support safety, efficacy, and durability of this minimally invasive sacroiliac posterior fusion LinQ allograft implant (NCT04423120). Preliminary results were reported previously. Final results for the full participant cohort are presented here.
    Results: One-hundred and fifty-nine (159) participants were enrolled across 16 investigational sites in the US between January 2020 and March 2022. One-hundred and twenty-two (122) participants were implanted. At the 1-month follow-up, 82 participants satisfied all criteria for the composite responder endpoint, representing 73.2% of the study cohort. These results stayed consistent across the remaining study timepoints with 66.0%, 74.4%, and 73.5% of participants classified as responders at the 3-, 6- and 12-month follow-up visits, respectively. VAS scores were significantly reduced (p < 0.0001) and ODI scores were significantly improved (p < 0.0001). All domains of the PROMIS-29 were also significantly improved (all p's <0.0001). Only one procedure-related serious AE was reported in the study.
    Conclusion: These results suggest that the posterior approach LinQ Implant System is a safe and effective treatment for sacroiliac joint dysfunction at 12 months, with results that are favorable compared to outcomes reported for an FDA-cleared lateral approach.
    Language English
    Publishing date 2024-03-20
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2495284-9
    ISSN 1178-7090
    ISSN 1178-7090
    DOI 10.2147/JPR.S458334
    Database MEDical Literature Analysis and Retrieval System OnLINE

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