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  1. Article ; Online: Six Decades of Philatelic Vignettes: In Honor of Dr Robert A. Kyle's Contributions to Medicine and Stamps.

    Steensma, David P / Witzig, Thomas E

    Mayo Clinic proceedings

    2023  Volume 98, Issue 11, Page(s) 1737–1739

    MeSH term(s) Humans ; Medicine ; Philately
    Language English
    Publishing date 2023-11-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2023.09.012
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  2. Article ; Online: Misleading Medical Stamps: The 2022 "Monkeypox" Issues.

    Steensma, David P / Witzig, Thomas E

    Mayo Clinic proceedings

    2023  Volume 99, Issue 1, Page(s) 179–180

    MeSH term(s) Humans ; Mpox (monkeypox) ; Philately
    Language English
    Publishing date 2023-11-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2023.11.011
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  3. Article ; Online: Myc matters in HIV-associated lymphoma.

    Witzig, Thomas E

    Blood

    2020  Volume 136, Issue 11, Page(s) 1217–1218

    MeSH term(s) HIV Infections/complications ; Humans ; Lymphoma ; Lymphoma, Non-Hodgkin ; Vorinostat
    Chemical Substances Vorinostat (58IFB293JI)
    Language English
    Publishing date 2020-09-19
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2020006651
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  4. Article ; Online: What Is Responsible for Heterogeneity in Mantle Cell Lymphoma Biology and Outcomes?

    Witzig, Thomas E

    Hematology/oncology clinics of North America

    2020  Volume 34, Issue 5, Page(s) 825–835

    Abstract: Mantle cell lymphoma, despite its common derivation from a t(11;14) error that occurs in a naïve B-cell leading to overexpression of cyclin D1 protein, is characterized by substantial heterogeneity in biology and clinical outcome. Unlike other non- ... ...

    Abstract Mantle cell lymphoma, despite its common derivation from a t(11;14) error that occurs in a naïve B-cell leading to overexpression of cyclin D1 protein, is characterized by substantial heterogeneity in biology and clinical outcome. Unlike other non-Hodgkin lymphoma types, it is more common in men. Clinical presentation patterns vary from nodal to splenomegaly with leukemia to gastrointestinal involvement. Biological variability is linked to tumor cell proliferation. Increased monocyte/macrophages and their associated proinflammatory cytokines are associated with inferior outcomes. These clues mandate that new treatments should target signal pathways that contribute to these adverse outcomes.
    MeSH term(s) B-Lymphocytes/metabolism ; B-Lymphocytes/pathology ; Chromosomes, Human, Pair 11/genetics ; Chromosomes, Human, Pair 11/metabolism ; Chromosomes, Human, Pair 14/genetics ; Chromosomes, Human, Pair 14/metabolism ; Cyclin D1/biosynthesis ; Cyclin D1/genetics ; Cytokines/genetics ; Cytokines/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; Lymphoma, Mantle-Cell/genetics ; Lymphoma, Mantle-Cell/metabolism ; Lymphoma, Mantle-Cell/pathology ; Lymphoma, Mantle-Cell/therapy ; Macrophages/pathology ; Organ Specificity ; Signal Transduction ; Translocation, Genetic
    Chemical Substances CCND1 protein, human ; Cytokines ; Cyclin D1 (136601-57-5)
    Language English
    Publishing date 2020-07-26
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 93115-9
    ISSN 1558-1977 ; 0889-8588
    ISSN (online) 1558-1977
    ISSN 0889-8588
    DOI 10.1016/j.hoc.2020.06.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Hematoxylin: From Logwood Trees to Microscope Slides.

    Steensma, David P / Loghavi, Sanam / Witzig, Thomas E

    Mayo Clinic proceedings

    2023  Volume 98, Issue 9, Page(s) 1429–1430

    MeSH term(s) Humans ; Hematoxylin ; Trees
    Chemical Substances Hematoxylin (YKM8PY2Z55)
    Language English
    Publishing date 2023-09-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2023.07.016
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  6. Article ; Online: Maintenance Lenalidomide for Large-Cell Lymphoma: Who Really Benefits?

    Witzig, Thomas E

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2017  Volume 35, Issue 22, Page(s) 2459–2460

    MeSH term(s) Adult ; Aged ; Child ; Cyclophosphamide ; Doxorubicin ; Humans ; Lenalidomide ; Lymphoma, Large B-Cell, Diffuse ; Neoplasm Recurrence, Local ; Prednisone ; Rituximab ; Vincristine
    Chemical Substances Rituximab (4F4X42SYQ6) ; Vincristine (5J49Q6B70F) ; Doxorubicin (80168379AG) ; Cyclophosphamide (8N3DW7272P) ; Lenalidomide (F0P408N6V4) ; Prednisone (VB0R961HZT)
    Language English
    Publishing date 2017-05-17
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.2017.73.2578
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The asymptomatic follicular lymphoma (AFL) trial: single-agent rituximab immunotherapy versus 90Y-ibritumomab tiuxetan radioimmunotherapy (RIT) for patients with new, untreated follicular lymphoma.

    Laoruangroj, Chonlada / Atherton, Pamela J / Wiseman, Gregory A / Ansell, Stephen / Feldman, Andrew L / Schumacher, Peyton / Witzig, Thomas E

    Leukemia & lymphoma

    2024  Volume 65, Issue 3, Page(s) 333–338

    Abstract: Patients with asymptomatic follicular lymphoma (AFL) are candidates for observation or immunotherapy. Given the effectiveness of radiation therapy in FL, another option is 90Yttrium-ibritumomab tiuxetan radioimmunotherapy (RIT). We conducted a trial ... ...

    Abstract Patients with asymptomatic follicular lymphoma (AFL) are candidates for observation or immunotherapy. Given the effectiveness of radiation therapy in FL, another option is 90Yttrium-ibritumomab tiuxetan radioimmunotherapy (RIT). We conducted a trial where untreated AFL patients were randomized to rituximab 375 mg/m2 weekly × 4 or rituximab 250 mg/m
    MeSH term(s) Humans ; Rituximab/therapeutic use ; Lymphoma, Follicular/diagnosis ; Lymphoma, Follicular/therapy ; Radioimmunotherapy ; Yttrium Radioisotopes/therapeutic use ; Lymphoma, Non-Hodgkin/therapy ; Treatment Outcome ; Antibodies, Monoclonal
    Chemical Substances Rituximab (4F4X42SYQ6) ; ibritumomab tiuxetan (4Q52C550XK) ; Yttrium-90 (1K8M7UR6O1) ; Yttrium Radioisotopes ; Antibodies, Monoclonal
    Language English
    Publishing date 2024-01-08
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 1042374-6
    ISSN 1029-2403 ; 1042-8194
    ISSN (online) 1029-2403
    ISSN 1042-8194
    DOI 10.1080/10428194.2023.2295792
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Work-Life Balance Solutions for Physicians-It's All About You, Your Work, and Others.

    Witzig, Thomas E / Smith, Sonali M

    Mayo Clinic proceedings

    2019  Volume 94, Issue 4, Page(s) 573–576

    MeSH term(s) Burnout, Professional/prevention & control ; Humans ; Job Satisfaction ; Physicians/psychology ; Quality of Life/psychology ; Social Support ; Work-Life Balance ; Workplace/psychology
    Language English
    Publishing date 2019-04-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2018.11.021
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  9. Article: A new tool in the cancer immunotherapy toolbox?

    Wu, Xiaosheng / Witzig, Thomas E

    Annals of lymphoma

    2018  Volume 2, Issue 3

    Language English
    Publishing date 2018-03-20
    Publishing country China
    Document type Journal Article ; Comment
    DOI 10.21037/aol.2018.03.01
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Acalabrutinib for mantle cell lymphoma.

    Witzig, Thomas E / Inwards, David

    Blood

    2019  Volume 133, Issue 24, Page(s) 2570–2574

    Abstract: Mantle cell lymphoma (MCL) is a unique type of non-Hodgkin lymphoma characterized by the overexpression of cyclin D1. MCL patients typically live for years but experience multiple relapses. Acalabrutinib is a novel second-generation oral Bruton tyrosine ... ...

    Abstract Mantle cell lymphoma (MCL) is a unique type of non-Hodgkin lymphoma characterized by the overexpression of cyclin D1. MCL patients typically live for years but experience multiple relapses. Acalabrutinib is a novel second-generation oral Bruton tyrosine kinase inhibitor approved by the US Food and Drug Administration for relapsed MCL based on a clinical trial demonstrating an overall response rate of 81%. It provides a valuable new treatment option for MCL patients and is now being tested upfront.
    MeSH term(s) Antineoplastic Agents/therapeutic use ; Benzamides/therapeutic use ; Humans ; Lymphoma, Mantle-Cell/drug therapy ; Protein Kinase Inhibitors/therapeutic use ; Pyrazines/therapeutic use
    Chemical Substances Antineoplastic Agents ; Benzamides ; Protein Kinase Inhibitors ; Pyrazines ; acalabrutinib (I42748ELQW)
    Language English
    Publishing date 2019-04-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2019852368
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