LIVIVO - Search results -

Search results

Result 1 - 10 of total 9881

Search options

Article: Phase specific analysis of herpes zoster associated pain data: a new statistical approach by R. B. Arani, S.-J. Soong, H. L. Weiss, M. J. Wood, P. A. Fiddian, J. W. Gnann and R. Whitley, Statistics in Medicine 2001; 20:2429-2439.

Kay, Richard

2006 Volume 25, Issue 2, Page(s) 359–360

MeSH term(s)	Data Interpretation, Statistical ; Herpes Zoster/complications ; Humans ; Pain/etiology ; Pain Measurement
Language	English
Publishing date	2006-01-30
Publishing country	England
Document type	Comment ; Letter
ZDB-ID	843037-8
ISSN	1097-0258 ; 0277-6715
ISSN (online)	1097-0258
ISSN	0277-6715
DOI	10.1002/sim.2280
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1756: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾

Article: Measurement of signs of chemical shift differences between ground and excited protein states: a comparison between H(S/M)QC and R ₁ρ methods

Auer, Renate / Hansen, D. Flemming / Neudecker, Philipp / Korzhnev, Dmitry M. / Muhandiram, D. Ranjith / Konrat, Robert / Kay, Lewis E.

Journal of biomolecular NMR. 2010 Mar., v. 46, no. 3

2010

Abstract: ... Analysis of CPMG data-sets also provides the magnitudes of the chemical shift difference(s) between ... exchanging states (|Δϖ|), that inform on the structural properties of the excited state(s). The sign of Δϖ is ... of ¹HN and ¹³Cα Δϖ values using weak off-resonance R ₁ρ relaxation measurements, extending the spin-lock ...

Abstract	Carr-Purcell-Meiboom-Gill (CPMG) relaxation dispersion NMR spectroscopy has emerged as a powerful tool for quantifying the kinetics and thermodynamics of millisecond exchange processes between a major, populated ground state and one or more minor, low populated and often invisible ‘excited' conformers. Analysis of CPMG data-sets also provides the magnitudes of the chemical shift difference(s) between exchanging states (\|Δϖ\|), that inform on the structural properties of the excited state(s). The sign of Δϖ is, however, not available from CPMG data. Here we present one-dimensional NMR experiments for measuring the signs of ¹HN and ¹³Cα Δϖ values using weak off-resonance R ₁ρ relaxation measurements, extending the spin-lock approach beyond previous applications focusing on the signs of ¹⁵N and ¹Hα shift differences. The accuracy of the method is established by using an exchanging system where the invisible, excited state can be converted to the visible, ground state by altering conditions so that the signs of Δϖ values obtained from the spin-lock approach can be validated with those measured directly. Further, the spin-lock experiments are compared with the established H(S/M)QC approach for measuring the signs of chemical shift differences. For the Abp1p and Fyn SH3 domains considered here it is found that while H(S/M)QC measurements provide signs for more residues than the spin-lock data, the two different methodologies are complementary, so that combining both approaches frequently produces signs for more residues than when the H(S/M)QC method is used alone.
Keywords	data collection ; nuclear magnetic resonance spectroscopy ; thermodynamics
Language	English
Dates of publication	2010-03
Size	p. 205-216.
Publisher	Springer Netherlands
Publishing place	Dordrecht
Document type	Article
ZDB-ID	1081696-3
ISSN	0925-2738
ISSN	0925-2738
DOI	10.1007/s10858-009-9394-z
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Cologne/Königswinter

Zs.A 4132: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Book ; Online: Benthic foraminifera in sapropels of the eastern Mediterranean Sea, supplementary data to: Schmiedl, Gerhard; Mitschele, A; Beck, S; Weldeab, Syee; Schulz, Hartmut; Hemleben, Christoph; Sperling, Michael R; Emeis, Kay-Christian (2003): Benthic foraminiferal record of ecosystem variability in the eastern Mediterranean Sea during times of sapropel S5 and S6 formation. Palaeogeography, Palaeoclimatology, Palaeoecology, 190, 139-164

Schmiedl, Gerhard / Beck, S / Emeis, Kay-Christian / Hemleben, Christoph / Mitschele, A / Schulz, Hartmut / Sperling, Michael R / Weldeab, Syee

2003

Abstract: High-resolution benthic foraminiferal and geochemical investigations were carried out across sapropels S5 and S6 from two sediment cores in the Levantine Sea to evaluate the impact of climatic and environmental changes on benthic ecosystems during times ... ...

Abstract	High-resolution benthic foraminiferal and geochemical investigations were carried out across sapropels S5 and S6 from two sediment cores in the Levantine Sea to evaluate the impact of climatic and environmental changes on benthic ecosystems during times of sapropel formation. The faunal successions indicate that eutrophication and/or oxygen reduction started several thousand years prior to the onset of sapropel formation, suggesting an early response of the bathyal ecosystems to climatic changes. Severest oxygen depletions appear in the early phases of sapropel formation. The initial reduction of deep-water ventilation is caused by a warming and fresh water-induced stratification of Eastern Mediterranean surface waters. During the late phase of S5 formation improved oxygenation is restricted to middle bathyal ecosystems, indicating that at least some formation of subsurface water took place. During S6 formation oxygen depletions and eutrophication were less severe and more variable than during S5 formation. Estimated oxygen contents were low dysoxic at middle bathyal to anoxic at lower bathyal depths during the early phase of S6 formation but never dropped to anoxic values in its late phase. The high benthic ecosystem variability during S6 formation suggests that water column stratification at deep-water formation sites was in a very unstable mode and susceptible to minor temperature fluctuations at a millennial time-scale.
Language	English
Dates of publication	2003-9999
Size	Online-Ressource
Publisher	PANGAEA - Data Publisher for Earth & Environmental Science
Publishing place	Bremen/Bremerhaven
Document type	Book ; Online
Note	This dataset is supplement to doi:10.1016/S0031-0182(02)00603-X
DOI	10.1594/PANGAEA.736661
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: The physical basis of osmosis.

Manning, Gerald S / Kay, Alan R

The Journal of general physiology

2023 Volume 155, Issue 10

Abstract: Osmosis is an important force in all living organisms, yet the molecular basis of osmosis is widely misunderstood as arising from diffusion of water across a membrane separating solutions of differing osmolarities, and hence different water ... ...

Abstract	Osmosis is an important force in all living organisms, yet the molecular basis of osmosis is widely misunderstood as arising from diffusion of water across a membrane separating solutions of differing osmolarities, and hence different water concentrations. In 1923, Peter Debye proposed a physical model for a semipermeable membrane emphasizing the repulsive forces between solute molecules and membrane that prevent the solute from entering the membrane. His work was hardly noticed at the time and slipped out of view. We show that Debye's analysis of van 't Hoff's law for osmotic equilibrium also provides a consistent and plausible mechanism for osmotic flow. A difference in osmolyte concentrations in solutions separated by a semipermeable membrane leads to different pressures at the two water-membrane interfaces because the total repulsive force between solute molecules and the membrane is different at the two interfaces. Water is therefore driven through the membrane for exactly the same reason that pure water flows in response to an imposed hydrostatic pressure difference. In this paper, we present the Debye model in both equilibrium and flow conditions. We point out its applicability regardless of the nature of the membrane with examples ranging from the predominantly convective flow of water through synthetic membranes and capillary walls to the purely diffusive flow of independent water molecules through a lipid bilayer and the flow of a single-file column of water molecules in narrow protein channels.
MeSH term(s)	Diffusion ; Lipid Bilayers ; Osmosis ; Pressure ; Water
Chemical Substances	Lipid Bilayers ; Water (059QF0KO0R)
Language	English
Publishing date	2023-08-25
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	3118-5
ISSN	1540-7748 ; 0022-1295
ISSN (online)	1540-7748
ISSN	0022-1295
DOI	10.1085/jgp.202313332
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uc I Zs.150: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Inference of dominant modes for linear stochastic processes.

MacKay, R S

Royal Society open science

2021 Volume 8, Issue 4, Page(s) 201442

Abstract: For dynamical systems that can be modelled as asymptotically stable linear systems forced by Gaussian noise, this paper develops methods to infer (estimate) their dominant modes from observations in real time. The modes can be real or complex. For a real ...

Abstract	For dynamical systems that can be modelled as asymptotically stable linear systems forced by Gaussian noise, this paper develops methods to infer (estimate) their dominant modes from observations in real time. The modes can be real or complex. For a real mode (monotone decay), the goal is to infer its damping rate and mode shape. For a complex mode (oscillatory decay), the goal is to infer its frequency, damping rate and (complex) mode shape. Their amplitudes and correlations are encoded in a mode covariance matrix that is also to be inferred. The work is motivated and illustrated by the problem of detection of oscillations in power flow in AC electrical networks. Suggestions of some other applications are given.
Language	English
Publishing date	2021-04-21
Publishing country	England
Document type	Journal Article
ZDB-ID	2787755-3
ISSN	2054-5703
ISSN	2054-5703
DOI	10.1098/rsos.201442
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Use of Stokes' theorem for plasma confinement.

MacKay, R S

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences

2020 Volume 378, Issue 2174, Page(s) 20190519

Abstract: Stokes' theorem, in its original form and Cartan's generalization, is crucial for designing magnetic fields to confine plasma (ionized gas). The paper illustrates its use, in particular to address the question whether quasi-symmetric fields, those for ... ...

Abstract	Stokes' theorem, in its original form and Cartan's generalization, is crucial for designing magnetic fields to confine plasma (ionized gas). The paper illustrates its use, in particular to address the question whether quasi-symmetric fields, those for which guiding-centre motion is integrable, can be made with little or no toroidal current. This article is part of the theme issue 'Stokes at 200 (Part 1)'.
Language	English
Publishing date	2020-06-08
Publishing country	England
Document type	Journal Article
ZDB-ID	208381-4
ISSN	1471-2962 ; 0080-4614 ; 0264-3820 ; 0264-3952 ; 1364-503X
ISSN (online)	1471-2962
ISSN	0080-4614 ; 0264-3820 ; 0264-3952 ; 1364-503X
DOI	10.1098/rsta.2019.0519
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 4' 46/25: Show issues
Z PHI 2: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Fecundity decline is male derived following transfluthrin exposures in a field strain of Aedes albopictus (Diptera: Culicidae).

McKay, Sean A / McKay, Conner J / Bibbs, Christopher S / Bloomquist, Jeffrey R / Kaufman, Phillip E

Journal of medical entomology

2024

Abstract: Volatile pyrethroids are effective in reducing mosquito populations and repelling vectors away from hosts. However, many gaps in knowledge exist for the sublethal impacts of volatile pyrethroids on mosquitoes. To that end, transfluthrin exposures were ... ...

Abstract	Volatile pyrethroids are effective in reducing mosquito populations and repelling vectors away from hosts. However, many gaps in knowledge exist for the sublethal impacts of volatile pyrethroids on mosquitoes. To that end, transfluthrin exposures were conducted on a field strain of Aedes albopictus (Skuse) held as a laboratory colony. Dose-response analysis was conducted on both sexes at either 1-4 days old or 5-10 days old. Resultant concentration data were used to evaluate the LC20 and LC50 values in various mate pairings of treatments and controls in which either the male or female was from a selectively treated group and mated with a counterpart that was treated independently. Blood feeding proportion, delayed mortality after a 24-h recovery period, egg collection totals, and F1 larval survival were determined following transfluthrin treatment in the F0, but outcomes were not significant. In contrast, sterility was predicated on male treatment, with treated females resulting in higher overall egg viability. Treated males in the mating pair resulted in significantly lower egg viability and accelerated larval hatch in the F1. Additionally, the presence of sperm in female spermathecae was significantly diminished in test groups containing treated male mosquitoes. Male sublethal effects may be a critical determinant of a mixed population's reproductive success.
Language	English
Publishing date	2024-02-16
Publishing country	England
Document type	Journal Article
ZDB-ID	410635-0
ISSN	1938-2928 ; 0022-2585
ISSN (online)	1938-2928
ISSN	0022-2585
DOI	10.1093/jme/tjae022
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 303: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Editorial: Ecology and molecular biology of bloom-forming cyanobacteria.

Bullerjahn, George S / McKay, R Michael L / Visser, Petra M

Frontiers in microbiology

2023 Volume 14, Page(s) 1346581

Language	English
Publishing date	2023-12-12
Publishing country	Switzerland
Document type	Editorial
ZDB-ID	2587354-4
ISSN	1664-302X
ISSN	1664-302X
DOI	10.3389/fmicb.2023.1346581
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Mapping of Family Reported Outcome Measure (FROM-16) scores to EQ-5D: algorithm to calculate utility values.

Shah, R / Salek, M S / Finlay, A Y / Kay, R / Nixon, S J / Otwombe, K / Ali, F M / Ingram, J R

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

2024 Volume 33, Issue 4, Page(s) 1107–1119

Abstract: Objective: Although decision scientists and health economists encourage inclusion of family member/informal carer utility in health economic evaluation, there is a lack of suitable utility measures comparable to patient utility measures such those based ...

Abstract	Objective: Although decision scientists and health economists encourage inclusion of family member/informal carer utility in health economic evaluation, there is a lack of suitable utility measures comparable to patient utility measures such those based on the EQ-5D. This study aims to predict EQ-5D-3L utility values from Family Reported Outcome Measure (FROM-16) scores, to allow the use of FROM-16 data in health economic evaluation when EQ-5D data is not available. Methods: Data from 4228 family members/partners of patients recruited to an online cross-sectional study through 58 UK-based patient support groups, three research support platforms and Welsh social services departments were randomly divided five times into two groups, to derive and test a mapping model. Split-half cross-validation was employed, resulting in a total of ten multinomial logistic regression models. The Monte Carlo simulation procedure was used to generate predicted EQ-5D-3L responses, and utility scores were calculated and compared against observed values. Mean error and mean absolute error were calculated for all ten validation models. The final model algorithm was derived using the entire sample. Results: The model was highly predictive, and its repeated fitting using multinomial logistic regression demonstrated a stable model. The mean differences between predicted and observed health utility estimates ranged from 0.005 to 0.029 across the ten modelling exercises, with an average overall difference of 0.015 (a 2.2% overestimate, not of clinical importance). Conclusions: The algorithm developed will enable researchers and decision scientists to calculate EQ-5D health utility estimates from FROM-16 scores, thus allowing the inclusion of the family impact of disease in health economic evaluation of medical interventions when EQ-5D data is not available.
MeSH term(s)	Humans ; Quality of Life/psychology ; Cross-Sectional Studies ; Surveys and Questionnaires ; Algorithms ; Patient Reported Outcome Measures
Language	English
Publishing date	2024-02-25
Publishing country	Netherlands
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	1161148-0
ISSN	1573-2649 ; 0962-9343
ISSN (online)	1573-2649
ISSN	0962-9343
DOI	10.1007/s11136-023-03590-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 3796: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: The origins of the D.S.I.R., reflections on ideas and men, 1915-1916

MacLeod, Roy M / Andrews, E. Kay

Public administration : an international quarterly Vol. 48 , p. 23-48

1970 Volume 48, Page(s) 23–48

Institution	D.S.I.R
Author's details	Roy M. MacLeod and E. Kay Andrews
Keywords	Industrieforschung ; Wissenschaftspflege ; Großbritannien
Publisher	Blackwell
Publishing place	Oxford [u.a.]
Document type	Article
ZDB-ID	210485-4
Database	ECONomics Information System

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED