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Article ; Online: Simulating social distancing measures in household and close contact transmission of SARS-CoV-2.

Garcia Filho, Carlos

2020 Volume 36, Issue 5, Page(s) e00099920

Abstract: We sought to evaluate contact rate reduction goals for household and close contacts and to provide preventive recommendations during the coronavirus pandemic. We applied an agent-based model to simulate the transmission dynamics of SARS-CoV-2 within ... ...

Abstract	We sought to evaluate contact rate reduction goals for household and close contacts and to provide preventive recommendations during the coronavirus pandemic. We applied an agent-based model to simulate the transmission dynamics of SARS-CoV-2 within household or close contacts through a social network of 150 nodes. there is no great difference in total infected people within modifications in number of links per node for networks with average number of links per node greater than three. For six nodes, total infected people are 149.85; for five nodes, 148.97; and for four nodes, 141.57. On the other hand, for three nodes, total infected are 82.39, for two nodes, 13.95; and for one node, 2.96. This model indicates a possible pitfall if social distancing measures are not stepwise suspended and close surveillance of cases are not provided, since the relationship between average links per node and number of infected people seems to be s-shaped, and not linear.
MeSH term(s)	Betacoronavirus ; Brazil/epidemiology ; COVID-19 ; Communicable Disease Control ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Family Characteristics ; Humans ; Models, Biological ; Pandemics/prevention & control ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; SARS-CoV-2 ; Social Isolation
Keywords	covid19
Language	English
Publishing date	2020-06-05
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	1115730-6
ISSN	1678-4464 ; 0102-311X
ISSN (online)	1678-4464
ISSN	0102-311X
DOI	10.1590/0102-311X00099920
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Book ; Online: Simulating social distancing measures in household and close contact transmission of SARS-CoV-2

Garcia Filho, Carlos

Cadernos de Saúde Pública v.36 n.5 2020

2020

Abstract	We sought to evaluate contact rate reduction goals for household and close contacts and to provide preventive recommendations during the coronavirus pandemic. We applied an agent-based model to simulate the transmission dynamics of SARS-CoV-2 within household or close contacts through a social network of 150 nodes. there is no great difference in total infected people within modifications in number of links per node for networks with average number of links per node greater than three. For six nodes, total infected people are 149.85; for five nodes, 148.97; and for four nodes, 141.57. On the other hand, for three nodes, total infected are 82.39, for two nodes, 13.95; and for one node, 2.96. This model indicates a possible pitfall if social distancing measures are not stepwise suspended and close surveillance of cases are not provided, since the relationship between average links per node and number of infected people seems to be s-shaped, and not linear.
Keywords	Infectious Disease Transmission ; Biological Models ; Severe Acute Respiratory Syndrome ; covid19
Subject code	003
Language	English
Publishing date	2020-01-01
Publisher	Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
Publishing country	br
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Post nirmatrelvir/ritonavir erythema multiforme in a patient with coronavirus disease infection.

Tavares-Júnior, José Wagner Leonel / Pompeu Filho, José Carlos Jucá / Galvão, Luiz Eduardo Garcia

Revista da Sociedade Brasileira de Medicina Tropical

2023 Volume 56, Page(s) e0008

Abstract: Erythema multiforme (EM), an immune-mediated skin condition, can occur after infection or following the use of medications. In this study, we describe a patient who developed EM after nirmatrelvir/ritonavir administration. An 81-year-old woman presented ... ...

Abstract	Erythema multiforme (EM), an immune-mediated skin condition, can occur after infection or following the use of medications. In this study, we describe a patient who developed EM after nirmatrelvir/ritonavir administration. An 81-year-old woman presented with fever and dyspnea. Laboratory investigations showed positive coronavirus disease (COVID-19) based on polymerase chain reaction assay, and she received a 5-day regimen of nirmatrelvir/ritonavir. We observed development of EM after this treatment and initiated prednisone (1 mg/kg) therapy, which led to rapid improvement. Our study is the first to report EM in a patient with COVID-19, who received nirmatrelvir/ritonavir and showed a favorable response.
MeSH term(s)	Female ; Humans ; Aged, 80 and over ; Ritonavir/adverse effects ; COVID-19 ; COVID-19 Drug Treatment ; Erythema Multiforme ; Antiviral Agents/therapeutic use
Chemical Substances	nirmatrelvir (7R9A5P7H32) ; Ritonavir (O3J8G9O825) ; Antiviral Agents
Language	English
Publishing date	2023-06-02
Publishing country	Brazil
Document type	Case Reports
ZDB-ID	1038126-0
ISSN	1678-9849 ; 0037-8682
ISSN (online)	1678-9849
ISSN	0037-8682
DOI	10.1590/0037-8682-0008-2023
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Article: Simulating social distancing measures in household and close contact transmission of SARS-CoV-2

Garcia Filho, Carlos

Cad Saude Publica

Abstract	We sought to evaluate contact rate reduction goals for household and close contacts and to provide preventive recommendations during the coronavirus pandemic. We applied an agent-based model to simulate the transmission dynamics of SARS-CoV-2 within household or close contacts through a social network of 150 nodes. there is no great difference in total infected people within modifications in number of links per node for networks with average number of links per node greater than three. For six nodes, total infected people are 149.85; for five nodes, 148.97; and for four nodes, 141.57. On the other hand, for three nodes, total infected are 82.39, for two nodes, 13.95; and for one node, 2.96. This model indicates a possible pitfall if social distancing measures are not stepwise suspended and close surveillance of cases are not provided, since the relationship between average links per node and number of infected people seems to be s-shaped, and not linear.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #32520073
Database	COVID19

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Article: In Vitro Activity of Quaternary Ammonium in

Arabe Filho, Marcelo Fagali / Jagielski, Tomasz / Proskurnicka, Angelika / Santos, Marcos Veiga Dos / Fidelis, Carlos Eduardo / Guimarães, Felipe Freitas / Guerra, Simony Trevizan / Joaquim, Sâmea Fernandes / Mioni, Mateus de Souza Ribeiro / Pantoja, José Carlos de Figueiredo / Langoni, Helio / Sanchez, Luísa Fernanda García / Ribeiro, Marcio Garcia

Animals : an open access journal from MDPI

2023 Volume 13, Issue 20

Abstract: The in vitro algaecide activity of quaternary ammonium (QA) ... ...

Abstract	The in vitro algaecide activity of quaternary ammonium (QA) against
Language	English
Publishing date	2023-10-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani13203286
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Article ; Online: 3-min All-out Test to Evaluate Aerobic and Anaerobic Indexes in Court Team Sports.

Kalva-Filho, Carlos Augusto / Andrade, Vitor Luiz / Garcia, Cynthia Giovana / Barbieri, Ricardo Augusto / da Silva, Henrique Santos / Dos-Santos, Julio Wilson / Papoti, Marcelo

International journal of sports medicine

2023 Volume 45, Issue 4, Page(s) 316–322

Abstract: This study aimed to test the reproducibility of the 3-min all-out effort applied using shuttle running and compare its values to aerobic parameters. On the first day, 14 futsal players underwent an exhaustive test to determine the maximal incremental ... ...

Abstract	This study aimed to test the reproducibility of the 3-min all-out effort applied using shuttle running and compare its values to aerobic parameters. On the first day, 14 futsal players underwent an exhaustive test to determine the maximal incremental speed (MIS) and anaerobic threshold (AnT). On the second day, the participants performed the 3-min all-out effort (n=14), which was repeated after 48 h (third day) to test its reproducibility (n=11). Peak oxygen consumption (V̇ O
MeSH term(s)	Humans ; Team Sports ; Exercise Test ; Reproducibility of Results ; Anaerobiosis ; Running ; Anaerobic Threshold ; Lactic Acid ; Oxygen Consumption
Chemical Substances	Lactic Acid (33X04XA5AT)
Language	English
Publishing date	2023-11-07
Publishing country	Germany
Document type	Journal Article
ZDB-ID	603122-5
ISSN	1439-3964 ; 0172-4622 ; 0943-917X
ISSN (online)	1439-3964
ISSN	0172-4622 ; 0943-917X
DOI	10.1055/a-2205-9108
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Article ; Online: Food and Nutrition Surveillance System: temporal trend of coverage and nutritional status of adults registered on the system, Brazil, 2008-2019.

Silva, Ruth Pereira Costa / Vergara, Clarice Maria Araújo Chagas / Sampaio, Helena Alves de Carvalho / Vasconcelos Filho, José Eurico / Strozberg, Felipe / Ferreira Neto, José Fernando Rodrigues / Mafra, Matheus Leite Pirani / Garcia Filho, Carlos / Carioca Filho, Antonio Augusto Ferreira

Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil

2022 Volume 31, Issue 1, Page(s) e2021605

Abstract: Objective: To analyze the temporal trend of Food and Nutrition Surveillance System (SISVAN) coverage and nutritional status of adults undergoing follow-up in the Brazilian Primary Health Care, 2008-2019.: Methods: This was an ecological time series ... ...

Title translation	Sistema de Vigilância Alimentar e Nutricional: tendência temporal da cobertura e estado nutricional de adultos registrados, 2008-2019.
Abstract	Objective: To analyze the temporal trend of Food and Nutrition Surveillance System (SISVAN) coverage and nutritional status of adults undergoing follow-up in the Brazilian Primary Health Care, 2008-2019. Methods: This was an ecological time series study using data on Brazilian macro-regions. The annual percent change in the classification of nutritional status and total coverage was estimated using the Prais-Winsten regression model. Results: A total of 115,034,534 records were identified in the period. Coverage increased from 5.0% in 2008 to 10.6% in 2019, with an annual change of 8.4%, 95% confidence interval (95%CI 6.7;10.0). Obesity and overweight showed a rising trend between 2008 and 2019, with an annual change of 6.4% (95%CI 5.3;7.3) and (1.8%; 95%CI 1.2;2.5) respectively, while underweight (-7.0%; 95%CI -8.0;-6.1) and eutrophy (-3.8%; 95%CI -4.1;-3.4) decreased in the period. Conclusion: There was an improvement in SISVAN coverage, with an increase in overweight and obesity among the population studied.
MeSH term(s)	Adult ; Brazil/epidemiology ; Food ; Humans ; Nutritional Status ; Obesity/epidemiology ; Overweight/epidemiology
Language	Portuguese
Publishing date	2022-04-15
Publishing country	Brazil
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2880588-4
ISSN	2237-9622 ; 1679-4974
ISSN (online)	2237-9622
ISSN	1679-4974
DOI	10.1590/S1679-49742022000100019
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Article ; Online: Post nirmatrelvir/ritonavir erythema multiforme in a patient with coronavirus disease infection

José Wagner Leonel Tavares-Júnior / José Carlos Jucá Pompeu Filho / Luiz Eduardo Garcia Galvão

Revista da Sociedade Brasileira de Medicina Tropical, Vol

2023 Volume 56

Abstract: ABSTRACT Erythema multiforme (EM), an immune-mediated skin condition, can occur after infection or following the use of medications. In this study, we describe a patient who developed EM after nirmatrelvir/ritonavir administration. An 81-year-old woman ... ...

Abstract	ABSTRACT Erythema multiforme (EM), an immune-mediated skin condition, can occur after infection or following the use of medications. In this study, we describe a patient who developed EM after nirmatrelvir/ritonavir administration. An 81-year-old woman presented with fever and dyspnea. Laboratory investigations showed positive coronavirus disease (COVID-19) based on polymerase chain reaction assay, and she received a 5-day regimen of nirmatrelvir/ritonavir. We observed development of EM after this treatment and initiated prednisone (1 mg/kg) therapy, which led to rapid improvement. Our study is the first to report EM in a patient with COVID-19, who received nirmatrelvir/ritonavir and showed a favorable response.
Keywords	COVID-19 ; Nirmatrelvir/ritonavir ; Erythema multiforme ; Arctic medicine. Tropical medicine ; RC955-962
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	Sociedade Brasileira de Medicina Tropical (SBMT)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Primary intestinal type mucinous adenocarcinoma of the ovary diagnosed during pregnancy - Maternal and neonatal treatment and outcomes: A case report.

Hase, Eliane Azeka / Shinohara, Henrique Norio / Alves Filho, João Alberto Garcia / Sadalla, José Carlos / Ab Saber, Alexandre Muxfeldt / Francisco, Rossana Pulcineli Vieira

Frontiers in medicine

2023 Volume 10, Page(s) 1138447

Abstract: The incidence of ovarian cancer during pregnancy is low. Most adnexal tumors removed during pregnancy are benign, with ovarian carcinomas found in approximately 1: 10,000-1: 50,000 pregnancies. Literature on this disease is scarce and consists mostly of ... ...

Abstract	The incidence of ovarian cancer during pregnancy is low. Most adnexal tumors removed during pregnancy are benign, with ovarian carcinomas found in approximately 1: 10,000-1: 50,000 pregnancies. Literature on this disease is scarce and consists mostly of retrospective studies and case reports. We report the case of a pregnant patient who presented with a primary intestinal-type mucinous adenocarcinoma of the ovary and underwent unilateral salpingo-oophorectomy, with no additional surgical or chemotherapy treatment after the histological diagnosis, despite an infiltrative stromal invasion pattern. To the best of our knowledge, no such case has been previously reported. Conservative treatment in this case of early ovarian carcinoma is possible during pregnancy and should be performed in the Department of Gynecological Oncology and Obstetrics of a tertiary referral hospital. Given the possibility of disease recurrence, such patients require strict clinical oncological surveillance, specialized prenatal care, and assistance from a multidisciplinary team to improve the maternal and perinatal outcomes.
Language	English
Publishing date	2023-03-29
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2775999-4
ISSN	2296-858X
ISSN	2296-858X
DOI	10.3389/fmed.2023.1138447
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Article ; Online: LIVER TRANSPLANT FOR METASTATIC NEUROENDOCRINE TUMORS: A SINGLE-CENTER REPORT.

Sampaio, Raquel Lima / Coelho, Gustavo Rego / Quidute, Ana Rosa Pinto / Rocha Filho, Duilio Reis da / Soares, Carlos Eduardo Lopes / Garcia, José Huygens Parente

Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery

2023 Volume 36, Page(s) e1750

Abstract: Background: Neuroendocrine tumors are rare neoplasms of uncertain biological behavior. The liver is one of the most common sites of metastases, occurring in 50% of patients with metastatic disease.: Aims: To analyze a clinical series in liver ... ...

Abstract	Background: Neuroendocrine tumors are rare neoplasms of uncertain biological behavior. The liver is one of the most common sites of metastases, occurring in 50% of patients with metastatic disease. Aims: To analyze a clinical series in liver transplant of patients with neuroendocrine tumors metastases. Methods: A retrospective descriptive study, based on the review of medical records of patients undergoing liver transplants due to neuroendocrine tumor metastases in a single center in northeast Brazil, over a period of 20 years (January 2001 to December 2021). Results: During the analyzed period, 2,000 liver transplants were performed, of which 11 were indicated for liver metastases caused by neuroendocrine tumors. The mean age at diagnosis was 45.09±14.36 years (26-66 years) and 72.7% of cases were females. The most common primary tumor site was in the gastrointestinal tract in 64% of cases. Even after detailed investigation, three patients had no primary tumor site identified (27%). Overall survival after transplantation at one month was 90%, at one year was 70%, and five year, 45.4%. Disease-free survival rate was 72.7% at one year and 36.3% at five years. Conclusions: Liver transplantation is a treatment modality with good overall survival and disease-free survival results in selected patients with unresectable liver metastases from neuroendocrine tumors. However, a rigorous selection of patients is necessary to obtain better results and the ideal time for transplant indication is still a controversial topic in the literature.
MeSH term(s)	Female ; Humans ; Male ; Neuroendocrine Tumors/surgery ; Neuroendocrine Tumors/pathology ; Liver Transplantation/methods ; Retrospective Studies ; Liver Neoplasms ; Disease-Free Survival
Language	English
Publishing date	2023-07-17
Publishing country	Brazil
Document type	Journal Article
ISSN	2317-6326
ISSN (online)	2317-6326
DOI	10.1590/0102-672020230032e1750
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