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  1. Article ; Online: Is it time for a precision health approach to the management of newborn hyperbilirubinemia?

    Stevenson, David K / Wells, Grant S / Wong, Ronald J

    Journal of perinatology : official journal of the California Perinatal Association

    2024  

    Abstract: Newborn hyperbilirubinemia during the first two weeks of life is one of most common problems requiring management decisions by a pediatrician. However, high bilirubin levels in the circulation have been associated with neurologic injury under a variety ... ...

    Abstract Newborn hyperbilirubinemia during the first two weeks of life is one of most common problems requiring management decisions by a pediatrician. However, high bilirubin levels in the circulation have been associated with neurologic injury under a variety of conditions encountered in the newborn infant, such as hemolysis. The risk for developing dangerous hyperbilirubinemia is multifactorial and is determined by a complex set of factors related to a newborn infant's genetic capacities as well as intra- and extrauterine exposures. To this end, a precision health approach based on the integration of prenatal genetic and postnatal diagnostic measures might improve the management of neonatal hyperbilirubinemia.
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 645021-0
    ISSN 1476-5543 ; 0743-8346
    ISSN (online) 1476-5543
    ISSN 0743-8346
    DOI 10.1038/s41372-024-01941-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Heme, Heme Oxygenase-1, Statins, and SARS-CoV-2.

    Stevenson, David K / Vreman, Hendrik J / Wong, Ronald J

    Antioxidants (Basel, Switzerland)

    2023  Volume 12, Issue 3

    Abstract: Heme, a metalloporphyrin, or more specifically, a tetrapyrrole containing ferrous iron, is an ancient molecule [ ... ]. ...

    Abstract Heme, a metalloporphyrin, or more specifically, a tetrapyrrole containing ferrous iron, is an ancient molecule [...].
    Language English
    Publishing date 2023-03-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox12030614
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Breath: The Exhaust of Metabolism.

    Stevenson, David K / Marić, Ivana / Wong, Ronald J

    The Journal of pediatrics

    2023  Volume 257, Page(s) 113386

    MeSH term(s) Humans ; Vehicle Emissions ; Respiratory System
    Chemical Substances Vehicle Emissions
    Language English
    Publishing date 2023-03-15
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2023.03.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: 1/f laws found in non-human music.

    Jermyn, Adam S / Stevenson, David J / Levitin, Daniel J

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 1324

    Abstract: A compelling question at the intersection of physics, neuroscience, and evolutionary biology concerns the extent to which the brains of various species evolved to encode regularities of the physical world. It would be parsimonious and adaptive, for ... ...

    Abstract A compelling question at the intersection of physics, neuroscience, and evolutionary biology concerns the extent to which the brains of various species evolved to encode regularities of the physical world. It would be parsimonious and adaptive, for example, for brains to evolve an innate understanding of gravity and the laws of motion, and to be able to detect, auditorily, those patterns of noises that ambulatory creatures make when moving about the world. One such physical regularity of the world is fractal structure, generally characterized by power-law correlations or 1/f
    MeSH term(s) Animals ; Music ; Brain ; Noise ; Fractals ; Physical Examination
    Language English
    Publishing date 2023-01-24
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-28444-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Molecular Mechanisms of Pregnancy-Related Vascular Remodeling and Pregnancy Complications.

    Stevenson, David K / Wong, Ronald J / Nayak, Nihar R

    International journal of molecular sciences

    2023  Volume 24, Issue 4

    Abstract: The purpose of this editorial is to highlight the various observations made in this Special Issue in the International Journal of Molecular Sciences [ ... ]. ...

    Abstract The purpose of this editorial is to highlight the various observations made in this Special Issue in the International Journal of Molecular Sciences [...].
    MeSH term(s) Pregnancy ; Female ; Humans ; Vascular Remodeling ; Pregnancy Complications
    Language English
    Publishing date 2023-02-13
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24043712
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A rapidly time-varying equatorial jet in Jupiter's deep interior.

    Bloxham, Jeremy / Cao, Hao / Stevenson, David J / Connerney, John E P / Bolton, Scott J

    Nature

    2024  Volume 627, Issue 8002, Page(s) 64–66

    Abstract: Planetary magnetic fields provide a window into the otherwise largely inaccessible dynamics of a planet's deep interior. In particular, interaction between fluid flow in electrically conducting interior regions and the magnetic field there gives rise to ... ...

    Abstract Planetary magnetic fields provide a window into the otherwise largely inaccessible dynamics of a planet's deep interior. In particular, interaction between fluid flow in electrically conducting interior regions and the magnetic field there gives rise to observable secular variation (time dependency) of the externally observed magnetic field. Secular variation of Jupiter's field has recently been revealed
    Language English
    Publishing date 2024-03-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/s41586-024-07046-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The placental vasculature is affected by changes in gene expression and glycogen-rich cells in a diet-induced obesity mouse model.

    Zhao, Hui / Wong, Ronald J / Stevenson, David K

    PloS one

    2023  Volume 18, Issue 11, Page(s) e0294185

    Abstract: Maternal obesity is a risk factor for pregnancy complications. Obesity caused by a high-fat diet (HFD) may alter maternal glucose/glycogen metabolism. Here, our objective was to investigate whether the placental vasculature is altered via changes in gene ...

    Abstract Maternal obesity is a risk factor for pregnancy complications. Obesity caused by a high-fat diet (HFD) may alter maternal glucose/glycogen metabolism. Here, our objective was to investigate whether the placental vasculature is altered via changes in gene expression and glycogen-rich cells using a preclinical mouse model of diet-induced obesity. We subjected female FVB/N mice to one of three feeding regimens: regular chow (RC) given at preconception and during pregnancy (Control); RC given at preconception and then a HFD during pregnancy (HFD-P); or HFD initiated 4 weeks preconception and during pregnancy (HFD-PreCP). Daily food consumption and weekly maternal weights were recorded. Maternal blood glucose levels were measured at preconception and 4 gestational epochs (E6.5-E9.5, E10.5-E12.5, E13.5-E15.5, E16.5-E19.5). At E8.5-E16.5, total RNA in placentas were isolated for gene expression analyses. Placentas were also collected for HE and periodic acid Schiff's (PAS) staining and glycogen content assays. Dams in the HFD-P and HFD-PreCP groups gained significantly more weight than controls. Pre- and antenatal glucose levels were also significantly higher (15%-30%) in HFD-PreCP dams. Expression of several placental genes were also altered in HFD dams compared with controls. Consumption of the HFD also led to phenotypic and morphologic changes in glycogen trophoblasts (GlyTs) and uterine natural killer (uNK) cells. Alterations in vascularity were also observed in the labyrinth of HFD-PreCP placentas, which correlated with decreased placental efficiency. Overall, we observed that a HFD induces gestational obesity in mice, alters expression of placental genes, affects glucose homeostasis, and alters glycogen-positive GlyTs and uNK cells. All these changes may lead to impaired placental vascular development, and thus heighten the risk for pregnancy complications.
    MeSH term(s) Humans ; Female ; Pregnancy ; Mice ; Animals ; Placenta/metabolism ; Obesity/genetics ; Obesity/metabolism ; Placentation ; Diet, High-Fat/adverse effects ; Pregnancy Complications/genetics ; Glucose/metabolism ; Glycogen/metabolism ; Gene Expression
    Chemical Substances Glucose (IY9XDZ35W2) ; Glycogen (9005-79-2)
    Language English
    Publishing date 2023-11-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0294185
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Care of the jaundiced neonate

    Stevenson, David K. / Maisels, M. J. / Watchko, Jon F.

    2012  

    Title variant Jaundiced neonate
    Author's details David K. Stevenson ; M. Jeffrey Maisels ; Jon F. Watchko
    Keywords Jaundice, Neonatal
    Language English
    Size XIII, 285 S. : Ill., graph. Darst.
    Publisher McGraw-Hill Med
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index ; Genetics of neonatal jaundice / Jon F. Watchko and Zhili Lin -- Bilirubin production and its measurement / David K. Stevenson, Hendrik J. Vreman, and Ronald J. Wong -- Bilirubin and its various fractions / Jane E. Brumbaugh and Glenn R. Gourley -- Bilirubin metabolism and transport / Cristina Bellarosa ... [et al.] -- Physiology of neonatal unconjugated hyperbilirubinemia / Thor Willy Ruud Hansen and Dag Bratlid -- The epidemiology of neonatal hyperbilirubinemia / M. Jeffrey Maisels and Thomas B. Newman -- Bilirubin toxicity / Dora Brites and Maria Alexandra Brito -- Hemolytic disorders and their management / Michael Kaplan and Cathy Hammerman -- Prevention, screening, and postnatal management of neonatal hyperbilirubinemia / M. Jeffrey Maisels and Thomas B. Newman -- Phototherapy and other treatments / M. Jeffrey Maisels ... [et al] -- Kernicterus / Steven Shapiro -- Public policy to prevent severe neonatal hyperbilirubinemia / Vinod K. Bhutani -- Neonatal jaundice in low-middle-income countries / Tina M. Slusher and Bolajoko O. Olusanya
    HBZ-ID HT017340506
    ISBN 978-0-07-176289-2 ; 0-07-176289-2
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2012 A 3258 order for loan Magazin

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  9. Article ; Online: 50 Years Ago in TheJournalofPediatrics: Advances in the Understanding of Prader-Willi syndrome.

    Stafford, Diane E J / Stevenson, David A

    The Journal of pediatrics

    2022  Volume 247, Page(s) 154

    MeSH term(s) Humans ; Prader-Willi Syndrome/diagnosis
    Language English
    Publishing date 2022-06-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3102-1
    ISSN 1097-6833 ; 0022-3476
    ISSN (online) 1097-6833
    ISSN 0022-3476
    DOI 10.1016/j.jpeds.2022.05.054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Challenges to the study of gender dysphoria.

    Stevenson, David K / Murray, Jeffrey C / Muglia, Louis J / Wong, Ronald J / Katz, Michael

    Acta paediatrica (Oslo, Norway : 1992)

    2023  Volume 112, Issue 11, Page(s) 2273–2275

    Language English
    Publishing date 2023-09-19
    Publishing country Norway
    Document type Journal Article
    ZDB-ID 203487-6
    ISSN 1651-2227 ; 0365-1436 ; 0803-5253
    ISSN (online) 1651-2227
    ISSN 0365-1436 ; 0803-5253
    DOI 10.1111/apa.16975
    Database MEDical Literature Analysis and Retrieval System OnLINE

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