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  1. Book ; Conference proceedings: Vertical structure in aquatic environments and its impact on trophic linkages and nutrient fluxes /ed. by Colin S. Reynolds and Yasunori Watanabe

    Reynolds, Colin S / Watanabe, Yasunori

    (Archiv für Hydrobiologie : Beiheft, Ergebnisse der Limnologie ; 35)

    1992  

    Event/congress International Congress in Ecology (5, 1990.08.23-30, YokohamaJapan)
    Series title Archiv für Hydrobiologie : Beiheft, Ergebnisse der Limnologie ; 35
    Language Undetermined
    Size VI, 159 S, graph. Darst
    Publisher Schweizerbart
    Publishing place Stuttgart
    Document type Book ; Conference proceedings
    ISBN 3510470362 ; 9783510470365
    Database Former special subject collection: coastal and deep sea fishing

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  2. Book ; Conference proceedings: Vertical structure in aquatic environments and its impact on trophic linkages and nutrient fluxes /ed. by Colin S. Reynolds and Yasunori Watanabe

    Reynolds, Colin S / Watanabe, Yasunori

    (Archiv für Hydrobiologie : Beiheft, Ergebnisse der Limnologie ; 35)

    1992  

    Event/congress International Congress in Ecology (5, 1990.08.23-30, YokohamaJapan)
    Series title Archiv für Hydrobiologie : Beiheft, Ergebnisse der Limnologie ; 35
    Language English
    Size VI, 159 S, graph. Darst
    Publisher Schweizerbart
    Publishing place Stuttgart
    Document type Book ; Conference proceedings
    ISBN 3510470362 ; 9783510470365
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  3. Article ; Online: The activation mechanism of Atg15, a vacuolar phospholipase required for the disintegration of organelle membranes.

    Watanabe, Yasunori / Suzuki, Kuninori

    Autophagy

    2024  , Page(s) 1–2

    Abstract: The disintegration of cytoplasm-to-vacuole targeting (Cvt) bodies and autophagic bodies in vacuoles is essential to the Cvt pathway and macroautophagy in yeast. Atg15 is a vacuolar lipase required for the degradation of both Cvt and autophagic bodies. ... ...

    Abstract The disintegration of cytoplasm-to-vacuole targeting (Cvt) bodies and autophagic bodies in vacuoles is essential to the Cvt pathway and macroautophagy in yeast. Atg15 is a vacuolar lipase required for the degradation of both Cvt and autophagic bodies. However, the molecular mechanism of their degradation by Atg15 remains poorly understood. In a recent study, we showed that recombinant
    Language English
    Publishing date 2024-03-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2454135-7
    ISSN 1554-8635 ; 1554-8627
    ISSN (online) 1554-8635
    ISSN 1554-8627
    DOI 10.1080/15548627.2024.2333165
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6741: Show issues Location:
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  4. Article ; Online: Molecular evolutionary insight of structural zinc atom in yeast xylitol dehydrogenases and its application in bioethanol production by lignocellulosic biomass.

    Yoshiwara, Kentaroh / Watanabe, Seiya / Watanabe, Yasunori

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 1920

    Abstract: Xylitol dehydrogenase (XDH) catalyzes the ... ...

    Abstract Xylitol dehydrogenase (XDH) catalyzes the NAD
    MeSH term(s) Saccharomyces cerevisiae/metabolism ; D-Xylulose Reductase/genetics ; D-Xylulose Reductase/chemistry ; D-Xylulose Reductase/metabolism ; Xylitol/metabolism ; Zinc/metabolism ; Cysteine/metabolism ; Biomass ; Pichia/metabolism ; Xylose/metabolism ; Aldehyde Reductase/genetics ; Fermentation
    Chemical Substances D-Xylulose Reductase (EC 1.1.1.9) ; Xylitol (VCQ006KQ1E) ; Zinc (J41CSQ7QDS) ; Cysteine (K848JZ4886) ; lignocellulose (11132-73-3) ; Xylose (A1TA934AKO) ; Aldehyde Reductase (EC 1.1.1.21)
    Language English
    Publishing date 2023-02-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-29195-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Modified Commando procedure using a double valve composite through an aorto-annulo-septotomy.

    Matsuzaki, Kanji / Mitomi, Kisato / Imai, Akito / Sato, Masataka / Watanabe, Yasunori

    Interdisciplinary cardiovascular and thoracic surgery

    2024  Volume 38, Issue 1

    Abstract: Double valve replacement of aortic and mitral valves with intervalvular fibrous body reconstruction (Commando procedure) is a challenging operation. Particularly in redo surgery for prosthetic valve endocarditis, special techniques are needed for ... ...

    Abstract Double valve replacement of aortic and mitral valves with intervalvular fibrous body reconstruction (Commando procedure) is a challenging operation. Particularly in redo surgery for prosthetic valve endocarditis, special techniques are needed for approaching and reconstructing the valve complex. We performed a modified Commando procedure using a double valve composite through an aorto-annulo-septotomy. This approach provided a good field of vision at the combined aortic and mitral annuli without incising the left atrial roof. The double valve composite with four-layer patch wings was useful for performing double valve replacement en bloc and aorto-annulo-septotomy closure serially. Using these techniques, we successfully performed the Commando procedure for complicated prosthetic valve endocarditis.
    Language English
    Publishing date 2024-01-03
    Publishing country England
    Document type Journal Article
    ISSN 2753-670X
    ISSN (online) 2753-670X
    DOI 10.1093/icvts/ivad213
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Molecular evolutionary insight of structural zinc atom in yeast xylitol dehydrogenases and its application in bioethanol production by lignocellulosic biomass

    Kentaroh Yoshiwara / Seiya Watanabe / Yasunori Watanabe

    Scientific Reports, Vol 13, Iss 1, Pp 1-

    2023  Volume 14

    Abstract: Abstract Xylitol dehydrogenase (XDH) catalyzes the NAD+-dependent oxidization of xylitol into d-xylulose, and belongs to a zinc-dependent medium-chain dehydrogenase/reductase family. This protein family consists of enzymes with one or two zinc atoms per ... ...

    Abstract Abstract Xylitol dehydrogenase (XDH) catalyzes the NAD+-dependent oxidization of xylitol into d-xylulose, and belongs to a zinc-dependent medium-chain dehydrogenase/reductase family. This protein family consists of enzymes with one or two zinc atoms per subunit, among which catalytic zinc is necessary for the activity. Among many XDHs from yeast and fungi, XDH from Pichia stipitis is one of the key enzymes for bioethanol production by lignocellulosic biomass, and possesses only a catalytic zinc atom. Despite its importance in bioindustry, a structural data of XDH has not yet been available, and little insight into the role of a second zinc atom in this protein family is known. We herein report the crystal structure of XDH from P. stipitis using a thermostabilized mutant. In the refined structure, a second zinc atom clearly coordinated with four artificially introduced cysteine ligands. Homologous mutations in XDH from Saccharomyces cerevisiae also stabilized and enhanced activity. The substitution of each of the four cysteine ligands with an aspartate in XDH from Schizosaccharomyces pombe contributed to the significantly better maintenance of activity and thermostability than their substitution with a serine, providing a novel hypothesis for how this zinc atom was eliminated.
    Keywords Medicine ; R ; Science ; Q
    Subject code 540
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  7. Article ; Online: Crystal structure of L-arabinose 1-dehydrogenase as a short-chain reductase/dehydrogenase protein.

    Watanabe, Seiya / Yoshiwara, Kentaroh / Matsubara, Ryo / Watanabe, Yasunori

    Biochemical and biophysical research communications

    2022  Volume 604, Page(s) 14–21

    Abstract: l-Arabinose 1-dehydrogenase (AraDH) catalyzes the NAD(P) ...

    Abstract l-Arabinose 1-dehydrogenase (AraDH) catalyzes the NAD(P)
    MeSH term(s) Arabinose/chemistry ; NAD/metabolism ; Oxidoreductases/metabolism ; Short Chain Dehydrogenase-Reductases/metabolism ; Substrate Specificity
    Chemical Substances NAD (0U46U6E8UK) ; Arabinose (B40ROO395Z) ; Oxidoreductases (EC 1.-) ; Short Chain Dehydrogenase-Reductases (EC 1.1.1.-)
    Language English
    Publishing date 2022-03-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 205723-2
    ISSN 1090-2104 ; 0006-291X ; 0006-291X
    ISSN (online) 1090-2104 ; 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2022.03.028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 116: Show issues Location:
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  8. Article ; Online: Crystal Structure of l-2,4-Diketo-3-deoxyrhamnonate Hydrolase Involved in the Nonphosphorylated l-Rhamnose Pathway from Bacteria.

    Fukuhara, Shota / Watanabe, Seiya / Watanabe, Yasunori / Nishiwaki, Hisashi

    Biochemistry

    2022  Volume 62, Issue 2, Page(s) 524–534

    Abstract: 2,4-Diketo-3-deoxy-l-rhamnonate (L-DKDR) hydrolase (LRA6) catalyzes the hydrolysis reaction of L-DKDR to pyruvate and l-lactate in the nonphosphorylated l-rhamnose pathway from bacteria and belongs to the fumarylacetoacetate hydrolase (FAH) superfamily. ... ...

    Abstract 2,4-Diketo-3-deoxy-l-rhamnonate (L-DKDR) hydrolase (LRA6) catalyzes the hydrolysis reaction of L-DKDR to pyruvate and l-lactate in the nonphosphorylated l-rhamnose pathway from bacteria and belongs to the fumarylacetoacetate hydrolase (FAH) superfamily. Most of the members of the FAH superfamily are involved in the microbial degradation of aromatic substances and share low sequence similarities with LRA6, by which the underlying catalytic mechanism remains unknown at the atomic level. We herein elucidated for the first time the crystal structures of LRA6 from
    MeSH term(s) Animals ; Rhamnose/metabolism ; Phylogeny ; Ligands ; Hydrolases/chemistry ; Bacteria/metabolism ; Pyruvates ; Crystallography, X-Ray ; Mammals/metabolism
    Chemical Substances Rhamnose (QN34XC755A) ; Ligands ; Hydrolases (EC 3.-) ; Pyruvates
    Language English
    Publishing date 2022-12-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1108-3
    ISSN 1520-4995 ; 0006-2960
    ISSN (online) 1520-4995
    ISSN 0006-2960
    DOI 10.1021/acs.biochem.2c00596
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 217: Show issues Location:
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  9. Article ; Online: HIV-associated CD8+ T-cell Skin Infiltrative Disease and EBV-associated Polymorphic B-cell Lymphoproliferative Disorder in an AIDS Patient Who Improved Dramatically with Antiretroviral Therapy Alone.

    Okada, Naoki / Saito, Kenki / Watanabe, Momoko / Ohtani, Toshio / Notohara, Kenji / Wada, Hideho / Ueda, Yasunori

    Internal medicine (Tokyo, Japan)

    2024  

    Abstract: Human immunodeficiency virus (HIV)-associated CD8+ T-cell skin infiltrative disease with severe erythroderma has rarely been reported. While HIV-positive patients are prone to develop lymphoma, which is often associated with Epstein-Barr virus, ... ...

    Abstract Human immunodeficiency virus (HIV)-associated CD8+ T-cell skin infiltrative disease with severe erythroderma has rarely been reported. While HIV-positive patients are prone to develop lymphoma, which is often associated with Epstein-Barr virus, polymorphic lymphoproliferative disorder is rare, accounting for <5% of cases. We herein report a 41-year-old HIV-positive man who presented with a fever, erythroderma, and lymphadenopathy and was diagnosed with the coexistence of both diseases. His condition improved significantly with continued antiretroviral therapy. This case suggests that HIV-induced immunodeficiency is central to the pathogenesis of both entities and that improvement of the immunodeficient state is an effective treatment.
    Language English
    Publishing date 2024-01-02
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 32371-8
    ISSN 1349-7235 ; 0021-5120 ; 0918-2918
    ISSN (online) 1349-7235
    ISSN 0021-5120 ; 0918-2918
    DOI 10.2169/internalmedicine.2687-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 240: Show issues Location:
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  10. Article: A Case of Endovascular Aortic Repair for Abdominal Aortic Aneurysm with a Saccular Aneurysm in the Severely Angulated Proximal Landing Zone.

    Imai, Akito / Mitomi, Kisato / Sato, Masataka / Matsuzaki, Kanji / Watanabe, Yasunori

    Annals of vascular diseases

    2023  Volume 16, Issue 4, Page(s) 261–264

    Abstract: We report a case of endovascular aortic repair (EVAR) for the abdominal aortic aneurysm complicated by a saccular aneurysm due to a penetrating atherosclerotic ulcer in the severely angulated proximal landing zone. To secure the zone, coil embolization ... ...

    Abstract We report a case of endovascular aortic repair (EVAR) for the abdominal aortic aneurysm complicated by a saccular aneurysm due to a penetrating atherosclerotic ulcer in the severely angulated proximal landing zone. To secure the zone, coil embolization of the saccular aneurysm was performed before stent grafting to treat the abdominal aortic aneurysm. To precisely follow the severely angled proximal neck, we used the Excluder stent-graft system inserted by the body floss technique method instead of the stiff wire method to avoid accordion folding the proximal landing zone. These techniques may expand the indications of EVAR.
    Language English
    Publishing date 2023-09-30
    Publishing country Japan
    Document type Case Reports
    ZDB-ID 2394256-3
    ISSN 1881-6428 ; 1881-641X
    ISSN (online) 1881-6428
    ISSN 1881-641X
    DOI 10.3400/avd.cr.23-00038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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