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Article ; Online: Using the Photo-Piezoelectric Effect of AuPt@BaTiO

Liao, Yiquan / He, Yichang / Zhang, Bin / Ma, Ye / Xu, Ruiqi / Zhao, Minggang / Cui, Hongzhi

2024 Volume 24, Issue 7

Abstract: Nanozymes possess major advantages in catalysis and biosensing compared with natural nanozymes. In this study, the AuPt@ ... ...

Abstract	Nanozymes possess major advantages in catalysis and biosensing compared with natural nanozymes. In this study, the AuPt@BaTiO
MeSH term(s)	Colorimetry ; Alloys ; Catalysis ; Electrons ; Surface Plasmon Resonance
Chemical Substances	Alloys
Language	English
Publishing date	2024-03-31
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s24072242
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Heme as a differentiation-regulatory transcriptional cofactor.

Liao, Ruiqi / Bresnick, Emery H

International journal of hematology

2022 Volume 116, Issue 2, Page(s) 174–181

Abstract: The hematopoietic transcription factor GATA1 induces heme accumulation during erythropoiesis by directly activating genes mediating heme biosynthesis. In addition to its canonical functions as a hemoglobin prosthetic group and enzyme cofactor, heme ... ...

Abstract	The hematopoietic transcription factor GATA1 induces heme accumulation during erythropoiesis by directly activating genes mediating heme biosynthesis. In addition to its canonical functions as a hemoglobin prosthetic group and enzyme cofactor, heme regulates gene expression in erythroid cells both transcriptionally and post-transcriptionally. Heme binding to the transcriptional repressor BACH1 triggers its proteolytic degradation. In heme-deficient cells, BACH1 accumulates and represses transcription of target genes, including α- and β-like globin genes, preventing the accumulation of cytotoxic free globin chains. A recently described BACH1-independent mechanism of heme-dependent transcriptional regulation is associated with a DNA motif termed heme-regulated motif (HERM), which resides at the majority of loci harboring heme-regulated chromatin accessibility sites. Progress on these problems has led to a paradigm in which cell type-specific transcriptional mechanisms determine the expression of enzymes mediating the synthesis of small molecules, which generate feedback loops, converging upon the transcription factor itself and the genome. This marriage between transcription factors and the small molecules that they control is predicted to be a canonical attribute of regulatory networks governing cell state transitions such as differentiation in the hematopoietic system and more broadly.
MeSH term(s)	Basic-Leucine Zipper Transcription Factors/genetics ; Erythroid Cells ; Globins/metabolism ; Heme ; Humans ; Transcription Factors/metabolism
Chemical Substances	Basic-Leucine Zipper Transcription Factors ; Transcription Factors ; Heme (42VZT0U6YR) ; Globins (9004-22-2)
Language	English
Publishing date	2022-07-01
Publishing country	Japan
Document type	Journal Article ; Review
ZDB-ID	1076875-0
ISSN	1865-3774 ; 0917-1258 ; 0925-5710
ISSN (online)	1865-3774
ISSN	0917-1258 ; 0925-5710
DOI	10.1007/s12185-022-03404-x
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Zs.A 269: Show issues

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Article ; Online: Using the photo-enhanced barrier effect on electrochemical response for highly sensitive detection of melamine.

He, Yichang / Liao, Yiquan / Zhang, Bin / Xu, Ruiqi / Ma, Ye / Zhao, Minggang / Cui, Hongzhi

Food chemistry

2023 Volume 432, Page(s) 137246

Abstract: Melamine added to milk powder can lead to kidney injury and even death, but rapid detection is still hard due to the strong interference of milk powder solution. Herein, the CC/ ... ...

Abstract	Melamine added to milk powder can lead to kidney injury and even death, but rapid detection is still hard due to the strong interference of milk powder solution. Herein, the CC/CeO
MeSH term(s)	Powders ; Triazines ; Static Electricity
Chemical Substances	melamine (N3GP2YSD88) ; Powders ; Triazines
Language	English
Publishing date	2023-08-22
Publishing country	England
Document type	Journal Article
ZDB-ID	243123-3
ISSN	1873-7072 ; 0308-8146
ISSN (online)	1873-7072
ISSN	0308-8146
DOI	10.1016/j.foodchem.2023.137246
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Article ; Online: Mutations in BrABCG26, encoding an ATP-binding cassette transporter, are responsible for male sterility in Chinese cabbage (Brassica rapa L. ssp. pekinensis).

Xu, Junjie / Liao, Ruiqi / Xue, Meihui / Shang, Shayu / Zhou, Mingwei / Liu, Zhiyong / Feng, Hui / Huang, Shengnan

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik

2024 Volume 137, Issue 3, Page(s) 63

Abstract: Key message: The gene BrABCG26 responsible for male sterility of Chinese cabbage was confirmed by two allelic mutants. Male-sterile lines are an important way of heterosis utilization in Chinese cabbage. In this study, two allelic male-sterile mutants ... ...

Abstract	Key message: The gene BrABCG26 responsible for male sterility of Chinese cabbage was confirmed by two allelic mutants. Male-sterile lines are an important way of heterosis utilization in Chinese cabbage. In this study, two allelic male-sterile mutants msm3-1 and msm3-2 were obtained from a Chinese cabbage double haploid (DH) line 'FT' by using EMS-mutagenesis. Compared to the wild-type 'FT,' the stamens of mutants were completely degenerated and had no pollen, and other characters had no obvious differences. Cytological observation revealed that the failure of vacuolation of the mononuclear microspore, accompanied by abnormal tapetal degradation, resulted in anther abortion in mutants. Genetic analysis showed that a recessive gene controlled the mutant trait. MutMap combined with kompetitive allele specific PCR genotyping analyses showed that BraA01g038270.3C, encoding a transporter ABCG26 that played a vital role in pollen wall formation, was the candidate gene for msm3-1, named BrABCG26. Compared with wild-type 'FT,' the mutations existed on the second exon (C to T) and the sixth exon (C to T) of BrABCG26 gene in mutants msm3-1 and msm3-2, leading to the loss-of-function truncated protein, which verified the BrABCG26 function in stamen development. Subcellular localization and expression pattern analysis indicated that BrABCG26 was localized in the nucleus and was expressed in all organs, with the highest expression in flower buds. Compared to the wild-type 'FT,' the expressions of BrABCG26 were significantly reduced in flower buds and anthers of mutants. Promoter activity analysis showed that a strong GUS signal was detected in flower buds. These results indicated that BrABCG26 is responsible for the male sterility of msm3 mutants in Chinese cabbage.
MeSH term(s)	Male ; Humans ; Brassica rapa/genetics ; Gene Expression Profiling/methods ; ATP-Binding Cassette Transporters/genetics ; Plant Proteins/genetics ; Brassica/genetics ; Mutation ; Infertility, Male ; Gene Expression Regulation, Plant ; Plant Infertility/genetics
Chemical Substances	ATP-Binding Cassette Transporters ; Plant Proteins
Language	English
Publishing date	2024-03-01
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2170-2
ISSN	1432-2242 ; 0040-5752
ISSN (online)	1432-2242
ISSN	0040-5752
DOI	10.1007/s00122-024-04573-5
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Zs.A 1692: Show issues

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Article ; Online: Qualitative Analysis of Visible Foreign Solids in Armillarisin A Injection Formulations Using Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry.

Wang, Ruiqi / Zhou, Haichang / Liao, Shiyu / Tian, Qi / Lv, Zhengbing / Bao, Kangde / Liu, Lili

Molecules (Basel, Switzerland)

2023 Volume 28, Issue 4

Abstract: During the trial production of Armillarisin A for injection (AA-I), unidentified needle-like yellow-brown crystals were occasionally observed. Here, we report an ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS) method for ... ...

Abstract	During the trial production of Armillarisin A for injection (AA-I), unidentified needle-like yellow-brown crystals were occasionally observed. Here, we report an ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS) method for determining the source of the visible foreign bodies in the formulations of Armillarisin A active pharmaceutical ingredient (AA-API). AA-API, photolyzed samples, the intermediate polymer, and the excipient analyzed determined after the separation on a Waters Symmetry C18 (3.5 μm, 4.6 × 75 mm) column with a mobile phase consisting of a methanol/acetic acid (0.1 mol/L) aqueous solution (50:50). Furthermore, the crystal type of the visible foreign bodies, the intermediate polymer and AA-API were investigated by X-ray powder diffraction (XRD). The results revealed that the characteristics of the visible foreign solids were the same as those of AA-API as regards UPLC peak position (368 nm) and MS spectrum in negative ion detection mode. The visible foreign solids were thus identified as unpolymerized crystals of AA-API and were attributed to AA-API itself. The results showed that the production process could be improved by changing the stirring method and frequency as well as by optimizing the polymerization temperature to ensure the safety, stability, and control of the product quality in the stage of batch production.
MeSH term(s)	Chromatography, High Pressure Liquid/methods ; Chromatography, Liquid ; Tandem Mass Spectrometry/methods ; Benzopyrans
Chemical Substances	armillarisin A (M5864MH5CT) ; Benzopyrans
Language	English
Publishing date	2023-02-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules28041609
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Article ; Online: Petal-like g-C 3 N 4 Enhances the Photocatalyst Removal of Hexavalent Chromium

Huijuan Yu / Qiang Ma / Cuiping Gao / Shaohua Liao / Yingjie Zhang / Hong Quan / Ruiqi Zhai

Catalysts, Vol 13, Iss 641, p

2023 Volume 641

Abstract: The rapid progress of modern industry not only brings convenience to people’s lives, but also brings negative effects. Industrial development produces a large amount of waste metal, which brings harm to the environment and human health. Carbon nitride (g- ...

Abstract	The rapid progress of modern industry not only brings convenience to people’s lives, but also brings negative effects. Industrial development produces a large amount of waste metal, which brings harm to the environment and human health. Carbon nitride (g-C 3 N 4 ) was successfully prepared using the thermal-polymerization method and petal-like g-C 3 N 4 (CA-g-C 3 N 4 ) was impregnated with citric acid (CA). Compared with g-C 3 N 4 , CA-g-C 3 N 4 showed extremely high photocatalytic activity because the petal-like g-C 3 N 4 (CA-g-C 3 N 4 ) had a larger specific surface area, which increased the active sites on the surface of the photocatalyst and improved the photocatalytic activity. After citric acid treatment, the removal of hexavalent chromium (Cr(VI)) by g-C 3 N 4 increased from 48% to 93%. The photocatalytic materials were characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), Brunauer–Emmett–Teller (BET) and UV-vis diffuse reflectance spectra (UV-vis). In summary, this study confirmed that citric acid can improve the photocatalytic activity of g-C 3 N 4 by increasing its specific surface area and the active site of the photocatalytic material so as to achieve the purpose of removing hexavalent chromium from water.
Keywords	g-C 3 N 4 ; citric acid ; petal-like g-C 3 N 4 (CA-g-C 3 N 4 ) ; hexavalent chromium ; photocatalysis ; Chemical technology ; TP1-1185 ; Chemistry ; QD1-999
Subject code	290
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Uniform P2-K

Zhang, Zhuangzhuang / Hu, Qiao / Liao, Jiaying / Xu, Yifan / Duan, Liping / Tian, Ruiqi / Du, Yichen / Shen, Jian / Zhou, Xiaosi

Nano letters

2023 Volume 23, Issue 2, Page(s) 694–700

Abstract: Layered transition-metal (TM) oxides have drawn ever-growing interest as positive electrode materials in potassium-ion batteries (PIBs). Nevertheless, the practical implementation of these positive electrode materials is seriously hampered by their ... ...

Abstract	Layered transition-metal (TM) oxides have drawn ever-growing interest as positive electrode materials in potassium-ion batteries (PIBs). Nevertheless, the practical implementation of these positive electrode materials is seriously hampered by their inferior cyclic property and rate performance. Reported here is a self-templating strategy to prepare homogeneous P2-K
Language	English
Publishing date	2023-01-11
Publishing country	United States
Document type	Journal Article
ISSN	1530-6992
ISSN (online)	1530-6992
DOI	10.1021/acs.nanolett.2c04649
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Article ; Online: Thermo-responsive behavior and gelation of curdlan alkyl-ethers prepared by homogeneous reaction.

Wu, Min / Li, Ruiqi / Liao, Qingyu / Wang, Pengguang / Zhang, Hongbin

Carbohydrate polymers

2022 Volume 300, Page(s) 120248

Abstract: To resolve the major obstacles of poor water solubility and few functional derivatives in the practical utilization of curdlan, we prepared highly soluble and thermal-responsively alkylated curdlan with different degrees of substitution (DS) via ... ...

Abstract	To resolve the major obstacles of poor water solubility and few functional derivatives in the practical utilization of curdlan, we prepared highly soluble and thermal-responsively alkylated curdlan with different degrees of substitution (DS) via homogeneous reaction. The properties of these derivatives were investigated by rheology, inline attenuated total reflective-Fourier transform infrared spectroscopy, Raman and fluorescence spectroscopy, micro-differential scanning calorimetry, dynamic light scattering, and in vitro cytotoxicity assay. The newly developed methylated and ethylated curdlan can form thermal reversible heat-set hydrogels accompanied by volume shrinkage due to syneresis. Their gelation temperatures depend strongly on the DS, size of hydrophobic groups, and the order of the Hofmeister series salts added. Experimental results indicated that the gel network was induced by the enhanced hydrophobic interaction among macromolecular chains and weakened hydrogen bonding between the polymer and water on heating, leading to phase separation and gelation.
MeSH term(s)	Ethers ; beta-Glucans/chemistry ; Rheology ; Spectroscopy, Fourier Transform Infrared ; Hydrogels ; Water/chemistry
Chemical Substances	curdlan (6930DL209R) ; Ethers ; beta-Glucans ; Hydrogels ; Water (059QF0KO0R)
Language	English
Publishing date	2022-10-22
Publishing country	England
Document type	Journal Article
ZDB-ID	1501516-6
ISSN	1879-1344 ; 0144-8617
ISSN (online)	1879-1344
ISSN	0144-8617
DOI	10.1016/j.carbpol.2022.120248
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Article ; Online: Nanotrench Superfilling Facilitates Embedded Lithium Anode for High-Areal-Capacity Solid-State Batteries.

Shen, Chunli / Yan, Mengyu / Liao, Xiaobin / Xu, Ruiqi / Wang, Hong / Feng, Wencong / Yang, Wei / Li, Yan / Zhou, Cheng / Wang, Hanxiao / Xu, Xu / Mai, Liqiang

ACS nano

2024 Volume 18, Issue 6, Page(s) 5068–5078

Abstract: Solid-state batteries based on lithium metal anodes are expected to meet safety challenges while maintaining a high energy density. One major challenge lies in the fast interface degradation between the electrolyte and the lithium metal. Herein, we ... ...

Abstract	Solid-state batteries based on lithium metal anodes are expected to meet safety challenges while maintaining a high energy density. One major challenge lies in the fast interface degradation between the electrolyte and the lithium metal. Herein, we propose a quasi-3D interphase on a garnet solid-state electrolyte (SSE) by introducing lithiophilic nanotrenches. The nanotrenches created by the lithiophilic nanowire array can induce the superfilling of lithium metal into the nanotrenches, resulting in a low interfacial resistance (4 Ω cm
Language	English
Publishing date	2024-01-30
Publishing country	United States
Document type	Journal Article
ISSN	1936-086X
ISSN (online)	1936-086X
DOI	10.1021/acsnano.3c11724
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Book ; Online: Game Rewards Vulnerabilities

Wen, Xin-Cheng / Gao, Cuiyun / Wang, Xinchen / Wang, Ruiqi / Zhang, Tao / Liao, Qing

Software Vulnerability Detection with Zero-Sum Game and Prototype Learning

2024

Abstract: Recent years have witnessed a growing focus on automated software vulnerability detection. Notably, deep learning (DL)-based methods, which employ source code for the implicit acquisition of vulnerability patterns, have demonstrated superior performance ... ...

Abstract	Recent years have witnessed a growing focus on automated software vulnerability detection. Notably, deep learning (DL)-based methods, which employ source code for the implicit acquisition of vulnerability patterns, have demonstrated superior performance compared to other approaches. However, the DL-based approaches are still hard to capture the vulnerability-related information from the whole code snippet, since the vulnerable parts usually account for only a small proportion. As evidenced by our experiments, the approaches tend to excessively emphasize semantic information, potentially leading to limited vulnerability detection performance in practical scenarios. First, they cannot well distinguish between the code snippets before (i.e., vulnerable code) and after (i.e., non-vulnerable code) developers' fixes due to the minimal code changes. Besides, substituting user-defined identifiers with placeholders (e.g., "VAR1" and "FUN1") in obvious performance degradation at up to 14.53% with respect to the F1 score. To mitigate these issues, we propose to leverage the vulnerable and corresponding fixed code snippets, in which the minimal changes can provide hints about semantic-agnostic features for vulnerability detection. In this paper, we propose a software vulneRability dEteCtion framework with zerO-sum game and prototype learNing, named RECON. In RECON, we propose a zero-sum game construction module. Distinguishing the vulnerable code from the corresponding fixed code is regarded as one player (i.e. Calibrator), while the conventional vulnerability detection is another player (i.e. Detector) in the zero-sum game. The goal is to capture the semantic-agnostic features of the first player for enhancing the second player's performance for vulnerability detection. Experiments on the public benchmark dataset show that RECON outperforms the state-of-the-art baseline by 6.29% in F1 score. Comment: 17 pages, 8 figures
Keywords	Computer Science - Software Engineering ; Computer Science - Cryptography and Security
Subject code	303
Publishing date	2024-01-16
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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