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  1. Article: Coupled binding and folding of disordered SPIN N-terminal region in myeloperoxidase inhibition.

    Zhang, Yumeng / Liu, Xiaorong / Chen, Jianhan

    Frontiers in molecular biosciences

    2023  Volume 10, Page(s) 1130189

    Abstract: Gram-positive pathogenic ... ...

    Abstract Gram-positive pathogenic bacteria
    Language English
    Publishing date 2023-02-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2814330-9
    ISSN 2296-889X
    ISSN 2296-889X
    DOI 10.3389/fmolb.2023.1130189
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Tryptophan residue of plasmid-encoded Pgp3 is important for

    Huang, Yumeng / Wu, Haoqing / Sun, Yina / Liu, Yuanjun

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1216372

    Abstract: The crucial role of plasmid-encoded protein Pgp3 ... ...

    Abstract The crucial role of plasmid-encoded protein Pgp3 in
    Language English
    Publishing date 2023-07-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1216372
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Classification, Diagnosis and Management Status of Carbohydrate Metabolic Rare Disorders

    HUANG Yumeng / LIU Ming

    罕见病研究, Vol 2, Iss 3, Pp 325-

    2023  Volume 330

    Abstract: Approximately 30%-40% of rare diseases are related to the endocrine and metabolic system, and abnormal metabolism of carbohydrate accounts for a significant proportion among others. Carbohydrate metabolic rare disorders often develop insidiously. The ... ...

    Abstract Approximately 30%-40% of rare diseases are related to the endocrine and metabolic system, and abnormal metabolism of carbohydrate accounts for a significant proportion among others. Carbohydrate metabolic rare disorders often develop insidiously. The clinical symptoms of these disorders sometimes overlap with common diseases. Therefore, delayed diagnosis, misdiagnosis, and mismanagement happen often. The diagnosis and treatment of carbohydrate metabolic rare disorders is usually difficult in clinical practice. Efficient and practical screening models, identification of specific clinical features and biochemical changes, and genomic sequencing are critical to improve diagnostic efficiency. Most carbohydrate metabolic rare disorders are still lack in effective and targeted therapies. So, the symptomatic treatment is still main practice. The targeted medications and gene therapies based on precision diagnosis are directions for the diagnosis and management of rare disorders of carbohydrate metabolism in the future. In this paper, we classify the carbohydrate metabolic rare disorders based on their causes. We also discuss the current status and prospective of diagnosis and management of those diseases.
    Keywords carbohydrate metabolic disorders ; classification ; precision medicine ; rare diseases ; Medicine ; R
    Subject code 610
    Language Chinese
    Publishing date 2023-07-01T00:00:00Z
    Publisher Editorial Office of Journal of Rare Diseases
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: RMDGCN

    Lian Liu / Yumeng Zhou / Xiujuan Lei

    PLoS Computational Biology, Vol 19, Iss

    Prediction of RNA methylation and disease associations based on graph convolutional network with attention mechanism

    2023  Volume 12

    Keywords Biology (General) ; QH301-705.5
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Internet use, physical activity and depressive symptoms in older adults: A cross-lagged panel analysis.

    Liu, Ningning / Wang, Yumeng / Li, Zhirong

    Journal of affective disorders

    2024  Volume 350, Page(s) 937–945

    Abstract: Background: Existing cross-sectional studies suggest a strong positive association between Internet use, physical activity, and mental health in older adults; however, longitudinal studies reporting the relationship between Internet use, physical ... ...

    Abstract Background: Existing cross-sectional studies suggest a strong positive association between Internet use, physical activity, and mental health in older adults; however, longitudinal studies reporting the relationship between Internet use, physical activity, and levels of depressive symptoms in older adults are lacking. This study aimed to examine the bidirectional relationship between Internet use and depressive symptoms in older adults and its underlying mechanisms.
    Methods: We used two waves of follow-up data (2016 and 2018) from the China Family Panel Studies, including 5837 participants aged 60 years or above. The bidirectional relationship between Internet usage time and depressive symptoms was examined using a cross-lagged model. The mediating role of physical exercise was examined using a half-longitudinal mediation model.
    Results: The results revealed a bidirectional relationship between Internet use time, frequency of physical activity, and depressive symptoms. Longer Internet use predicted lower levels of depressive symptoms, and the frequency of physical activity mediated the longitudinal relationship between Internet use and depressive symptoms in older adults.
    Limitations: First, our study used self-report-based variables. Second, our study did not obtain the specific timing of the application of various functions of the Internet and the intensity of physical activity among older adults. Finally, based on the availability of data, our study involved only two waves of data. This may not be sufficient for a full longitudinal mediation effect test.
    Conclusions: Internet use and depressive symptoms were interrelated over time among older adults. The frequency of physical activity was a mediator of Internet use and depressive symptoms. This underscores the importance of Internet-based technologies to enable healthy living and prevent depression and loneliness in older adults.
    MeSH term(s) Humans ; Aged ; Internet Use ; Depression/psychology ; Cross-Sectional Studies ; Exercise/psychology ; Longitudinal Studies
    Language English
    Publishing date 2024-01-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 135449-8
    ISSN 1573-2517 ; 0165-0327
    ISSN (online) 1573-2517
    ISSN 0165-0327
    DOI 10.1016/j.jad.2024.01.201
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1485: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Named entity recognition in aerospace based on multi-feature fusion transformer

    Jing Chu / Yumeng Liu / Qi Yue / Zixuan Zheng / Xiaokai Han

    Scientific Reports, Vol 14, Iss 1, Pp 1-

    2024  Volume 14

    Abstract: Abstract In recent years, along with the rapid development in the domain of artificial intelligence and aerospace, aerospace combined with artificial intelligence is the future trend. As an important basic tool for Natural Language Processing, Named ... ...

    Abstract Abstract In recent years, along with the rapid development in the domain of artificial intelligence and aerospace, aerospace combined with artificial intelligence is the future trend. As an important basic tool for Natural Language Processing, Named Entity Recognition technology can help obtain key relevant knowledge from a large number of aerospace data. In this paper, we produced an aerospace domain entity recognition dataset containing 30 k sentences in Chinese and developed a named entity recognition model that is Multi-Feature Fusion Transformer (MFT), which combines features such as words and radicals to enhance the semantic information of the sentences. In our model, the double Feed-forward Neural Network is exploited as well to ensure MFT better performance. We use our aerospace dataset to train MFT. The experimental results show that MFT has great entity recognition performance, and the F1 score on aerospace dataset is 86.10%.
    Keywords Medicine ; R ; Science ; Q
    Subject code 006
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Cruise subsidy strategies in the post COVID-19 era: Refund risk, low-price dilemma

    Liu, Jiaguo / Xi, Yumeng

    Ocean and Coastal Management. 2023, p.106783-

    2023  , Page(s) 106783–

    Abstract: The COVID-19 pandemic has completely devastated the cruise industry in the past three years. Although the cruise market has gained hope for recovery with adequate control of the COVID-19 epidemic worldwide, small outbreaks in local areas will still bring ...

    Abstract The COVID-19 pandemic has completely devastated the cruise industry in the past three years. Although the cruise market has gained hope for recovery with adequate control of the COVID-19 epidemic worldwide, small outbreaks in local areas will still bring passengers and cruise lines a greater risk of ticket refunds, affecting the recovery of the cruise market. Therefore, governments and cruise lines should respond to these challenges by making adequate efforts to promote the revival of the cruise market. Using the Chinese cruise market as an example, we propose a cruise supply chain system that considers the risk of refunds and sets an upper limit for the government's subsidy budget to investigate the optimal subsidy strategy in the post-COVID-19 era. Our results show that subsidizing cruise lines is the best way to maximize market demand. However, subsidizing passengers is a better choice to prevent the Chinese cruise market from falling into the low-price dilemma. Fortunately, when the government's subsidy budget is not high, and the epidemic situation is optimistic (i.e., the risk of refund is low), if the brand advantage of the international cruise is high enough, subsidizing the cruise line can ensure the healthy development of the cruise market while expanding market demand more effectively. This conclusion will guide the transformation and upgrading of the Chinese cruise market.
    Keywords COVID-19 infection ; coastal zone management ; industry ; markets ; risk ; supply balance ; supply chain ; Government subsidy ; COVID-19 ; Risk of refund ; Budget constraint ; Brand advantage
    Language English
    Publishing place Elsevier Ltd
    Document type Article ; Online
    Note Pre-press version
    ISSN 0964-5691
    DOI 10.1016/j.ocecoaman.2023.106783
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Dimensions of family stress and repetitive nonsuicidal self-injury in adolescence: Examining the interactive effects of impulsivity and emotion dysregulation.

    Gao, Yemiao / Liu, Jinmeng / Liu, Xia / Wang, Yumeng / Qiu, Shaojie

    Child abuse & neglect

    2024  Volume 152, Page(s) 106804

    Abstract: Background: Repetitive non-suicidal self-injury (R-NSSI) in adolescence represents a significant risk factor for suicide. Although exposure to family stress is robustly associated with the risk of non-suicidal self-injury (NSSI), studies have not ... ...

    Abstract Background: Repetitive non-suicidal self-injury (R-NSSI) in adolescence represents a significant risk factor for suicide. Although exposure to family stress is robustly associated with the risk of non-suicidal self-injury (NSSI), studies have not examined the potential mechanisms linking different forms of family stress and R-NSSI.
    Objective: This study examined how unique dimensions of family stress (threat and deprivation) relate to R-NSSI via interactions between impulsivity and emotion dysregulation.
    Participants and setting: The current sample included 3801 middle-school adolescents (42.2 % girls, M
    Methods: We conducted a two-wave study with 6-month intervals. Participants completed self-report measures assessing family stress, impulsivity, emotion dysregulation, and NSSI.
    Results: Moderate mediation analyses showed that threat was indirectly associated with NSSI frequency through the interaction of impulsivity and emotion dysregulation in the R-NSSI group and indirectly through impulsivity in the occasional NSSI (O-NSSI) group. Deprivation did not predict subsequent NSSI frequency in either group.
    Conclusions: These findings lend empirical support to dimensional models of adversity and suggest that adolescents who experience threat-related family stress may have greater impulsivity and are more likely to report R-NSSI in the context of emotion dysregulation.
    Language English
    Publishing date 2024-04-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 799143-5
    ISSN 1873-7757 ; 0145-2134
    ISSN (online) 1873-7757
    ISSN 0145-2134
    DOI 10.1016/j.chiabu.2024.106804
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1437: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Named entity recognition in aerospace based on multi-feature fusion transformer.

    Chu, Jing / Liu, Yumeng / Yue, Qi / Zheng, Zixuan / Han, Xiaokai

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 827

    Abstract: In recent years, along with the rapid development in the domain of artificial intelligence and aerospace, aerospace combined with artificial intelligence is the future trend. As an important basic tool for Natural Language Processing, Named Entity ... ...

    Abstract In recent years, along with the rapid development in the domain of artificial intelligence and aerospace, aerospace combined with artificial intelligence is the future trend. As an important basic tool for Natural Language Processing, Named Entity Recognition technology can help obtain key relevant knowledge from a large number of aerospace data. In this paper, we produced an aerospace domain entity recognition dataset containing 30 k sentences in Chinese and developed a named entity recognition model that is Multi-Feature Fusion Transformer (MFT), which combines features such as words and radicals to enhance the semantic information of the sentences. In our model, the double Feed-forward Neural Network is exploited as well to ensure MFT better performance. We use our aerospace dataset to train MFT. The experimental results show that MFT has great entity recognition performance, and the F
    Language English
    Publishing date 2024-01-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-50705-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The biotic effects of lignite on humic acid components conversion during chicken manure composting.

    Wang, Yumeng / Han, Ziyi / Liu, Junping / Song, Caihong / Wei, Zimin

    Bioresource technology

    2024  Volume 398, Page(s) 130503

    Abstract: Targeted regulation of composting to convert organic matter into humic acid (HA) holds significant importance in compost quality. Owing to its low carbon content, chicken manure compost often requires carbon supplements to promote the humification ... ...

    Abstract Targeted regulation of composting to convert organic matter into humic acid (HA) holds significant importance in compost quality. Owing to its low carbon content, chicken manure compost often requires carbon supplements to promote the humification progress. The addition of lignite can increase HA content through biotic pathways, however, its structure was not explored. The Parallel factor analysis revealed that lignite can significantly increase the complexity of highly humified components. The lignite addition improved phenol oxidase activity, particularly laccase, during the thermophilic and cooling phases. The abundance and transformation functions of core bacteria also indicated that lignite addition can influence the activity of microbial transformation of HA components. The structural equation model further confirmed that lignite addition had a direct and indirect impact on enhancing the complexity of HA components through core bacteria and phenol oxidase. Therefore, lignite addition can improve HA structure complexity during composting through biotic pathways.
    MeSH term(s) Animals ; Humic Substances/analysis ; Soil ; Manure ; Composting ; Chickens ; Coal ; Monophenol Monooxygenase ; Carbon
    Chemical Substances Humic Substances ; Soil ; Manure ; Coal ; Monophenol Monooxygenase (EC 1.14.18.1) ; Carbon (7440-44-0)
    Language English
    Publishing date 2024-03-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 1065195-0
    ISSN 1873-2976 ; 0960-8524
    ISSN (online) 1873-2976
    ISSN 0960-8524
    DOI 10.1016/j.biortech.2024.130503
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 3258: Show issues

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