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  1. Article: Im Interview: R. Dörr, T. Meinertz, E. B. Ringelstein, P.-M. Schumm-Draeger. Corona: Mit weiteren Virus-Varianten muss gerechnet werden

    Dörr, R. / Meinertz, T. / Ringelstein, E. B. / Schumm-Draeger, P.-M.

    Diabetes, Stoffwechsel und Herz

    2022  Volume 31, Issue 1, Page(s) 50

    Language German ; English
    Document type Article
    ZDB-ID 2221060-X
    ISSN 1861-7603
    Database Current Contents Medicine

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  2. Book: Der ischämische Schlaganfall

    Ringelstein, Erich B. / Nabavi, Darius Günther

    eine praxisorientierte Darstellung von Pathophysiologie, Diagnostik und Therapie

    (Klinische Neurologie)

    2007  

    Author's details E. Bernd Ringelstein ; Darius G. Nabavi
    Series title Klinische Neurologie
    Keywords Schlaganfall
    Subject Apoplektischer Insult ; Apoplexia cerebri ; Apoplexie ; Gehirnschlag ; Hirnschlag ; Zerebrovaskulärer Insult ; ZVI ; Ischämischer Insult ; Stroke
    Language German
    Size 341 S. : Ill., graph. Darst.
    Edition 1. Aufl.
    Publisher Kohlhammer
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    HBZ-ID HT015105854
    ISBN 978-3-17-018853-2 ; 3-17-018853-4
    Database Catalogue ZB MED Medicine, Health

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  3. Book: Spezielle zerebrovaskuläre Krankheiten

    Nabavi, Darius Günther / Ringelstein, Erich B.

    intrakranielle Blutungen, Thrombosen und Ischämien

    (Klinische Neurologie)

    2007  

    Author's details Darius G. Nabavi ; E. Bernd Ringelstein
    Series title Klinische Neurologie
    Keywords Schlaganfall ; Hirnblutung
    Subject Intrazerebrales Hämatom ; Intrazerebralhämatom ; Intrazerebrale Blutung ; Intrakranielle Blutung ; Apoplektischer Insult ; Apoplexia cerebri ; Apoplexie ; Gehirnschlag ; Hirnschlag ; Zerebrovaskulärer Insult ; ZVI ; Ischämischer Insult ; Stroke
    Language German
    Size 227 S. : Ill.
    Edition 1. Aufl.
    Publisher Kohlhammer
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    HBZ-ID HT015105849
    ISBN 978-3-17-019355-0 ; 3-17-019355-4
    Database Catalogue ZB MED Medicine, Health

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  4. Article: Kognitive Störung und Demenz als Folge von Diabetes: Gespenst oder Realität?

    Ringelstein, E. B.

    Diabetes, metabolism, and the heart

    2018  Volume 27, Issue 1, Page(s) 50

    Language German ; English
    Document type Article
    ZDB-ID 2221060-X
    ISSN 1861-7603
    Database Current Contents Medicine

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  5. Book: Prävention und Behandlung arterieller Thromboembolien

    Ringelstein, E. B. / Riem, Ludger

    neue Aspekte zu Ticlopidin

    (The lancet : Dt. Ausg. ; [4],Jan., Beil.)

    1990  

    Author's details mit Beitr. von E. B. Ringelstein ... Zusammengefaßt von L. Riem
    Series title The lancet : Dt. Ausg. ; [4],Jan., Beil.
    The Lancet
    The lancet ; Dt. Ausg.
    Collection The Lancet
    The lancet ; Dt. Ausg.
    Keywords Cerebral Ischemia / drug therapy ; Thromboembolism / drug therapy ; Ticlopidine / therapeutic use
    Size 16 S. : Ill., graph. Darst.
    Publisher Schwer
    Publishing place Stuttgart
    Document type Book
    HBZ-ID HT003502352
    Database Catalogue ZB MED Medicine, Health

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  6. Article: Early Brain Volume Changes After Stroke: Subgroup Analysis From the AXIS-2 Trial.

    Bu, Ning / Churilov, Leonid / Khlif, Mohamed Salah / Lemmens, Robin / Wouters, Anke / Fiebach, Jochen B / Chamorro, Angel / Ringelstein, E Bernd / Norrving, Bo / Laage, Rico / Grond, Martin / Wilms, Guido / Brodtmann, Amy / Thijs, Vincent

    Frontiers in neurology

    2022  Volume 12, Page(s) 747343

    Abstract: Background and purpose: The evolution of total brain volume early after stroke is not well understood. We investigated the associations between age and imaging features and brain volume change in the first month after stroke.: Methods: We ... ...

    Abstract Background and purpose: The evolution of total brain volume early after stroke is not well understood. We investigated the associations between age and imaging features and brain volume change in the first month after stroke.
    Methods: We retrospectively studied patients with acute ischemic stroke enrolled in the AXIS-2 trial. Total brain volume change from hyperacute MRI data to the first month after stroke was assessed using unified segmentation in SPM12. We hypothesized that age, ischemic brain lesion size, and white matter (WM) changes were associated with larger brain volume change. Enlarged perivascular spaces (EPVSs) and white matter hyperintensities (WMHs) were rated visually and the presence of lacunes was assessed.
    Results: We enrolled 173 patients with a mean age of 67 ± 11 years, 44% were women. There was a median 6 ml decrease in volume (25th percentile -1 ml to 75th percentile 21 ml) over time, equivalent to a median 0.5% (interquartile range [IQR], -0.07%-1.4%), decrease in brain volume. Age was associated with larger brain volume loss (per 10 years of age, 5 ml 95%
    Conclusions: Total brain volume changes in a heterogenous fashion after stroke. Volume loss occurs over 1 month after stroke and is associated with age and deep WM disease. We did not find evidence that more severe strokes lead to increased early tissue loss.
    Language English
    Publishing date 2022-01-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2021.747343
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Ultrafast magnetic resonance imaging protocols in stroke.

    Ringelstein, E B

    Journal of neurology, neurosurgery, and psychiatry

    2005  Volume 76, Issue 7, Page(s) 905

    MeSH term(s) Cerebral Hemorrhage/diagnosis ; Cerebral Hemorrhage/drug therapy ; Cerebral Infarction/diagnosis ; Cerebral Infarction/drug therapy ; Diffusion Magnetic Resonance Imaging/methods ; Humans ; Image Enhancement/methods ; Image Processing, Computer-Assisted/methods ; Magnetic Resonance Imaging/methods ; Patient Selection ; Recurrence ; Thrombolytic Therapy ; Time Factors
    Language English
    Publishing date 2005-07
    Publishing country England
    Document type Comment ; Editorial
    ZDB-ID 3087-9
    ISSN 1468-330X ; 0022-3050
    ISSN (online) 1468-330X
    ISSN 0022-3050
    DOI 10.1136/jnnp.2004.060871
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Improving the sensitivity of myelin oligodendrocyte glycoprotein-antibody testing: exclusive or predominant MOG-IgG3 seropositivity-a potential diagnostic pitfall in patients with MOG-EM/MOGAD.

    Jarius, S / Ringelstein, M / Schanda, K / Ruprecht, K / Korporal-Kuhnke, M / Viehöver, A / Hümmert, M W / Schindler, P / Endmayr, V / Gastaldi, M / Trebst, C / Franciotta, D / Aktas, O / Höftberger, R / Haas, J / Komorowski, L / Paul, F / Reindl, M / Wildemann, B

    Journal of neurology

    2024  

    Abstract: ... assays later in the disease course (i.e. patients with spontaneous or treatment-driven seroreversion ...

    Abstract Background: Myelin oligodendrocyte glycoprotein antibody-associated encephalomyelitis (MOG-EM; also termed MOG antibody-associated disease, MOGAD) is the most important differential diagnosis of both multiple sclerosis and neuromyelitis optica spectrum disorders. A recent proposal for new diagnostic criteria for MOG-EM/MOGAD explicitly recommends the use of immunoglobulin G subclass 1 (IgG1)- or IgG crystallizable fragment (Fc) region-specific assays and allows the use of heavy-and-light-chain-(H+L) specific assays for detecting MOG-IgG. By contrast, the utility of MOG-IgG3-specific testing has not been systematically evaluated.
    Objective: To assess whether the use of MOG-IgG3-specific testing can improve the sensitivity of MOG-IgG testing.
    Methods: Re-testing of 22 patients with a definite diagnosis of MOG-EM/MOGAD and clearly positive MOG-IgG status initially but negative or equivocal results in H+L- or Fc-specific routine assays later in the disease course (i.e. patients with spontaneous or treatment-driven seroreversion).
    Results: In accordance with previous studies that had used MOG-IgG1-specific assays, IgG subclass-specific testing yielded a higher sensitivity than testing by non-subclass-specific assays. Using subclass-specific secondary antibodies, 26/27 supposedly seroreverted samples were still clearly positive for MOG-IgG, with MOG-IgG1 being the most frequently detected subclass (25/27 [93%] samples). However, also MOG-IgG3 was detected in 14/27 (52%) samples (from 12/22 [55%] patients). Most strikingly, MOG-IgG3 was the predominant subclass in 8/27 (30%) samples (from 7/22 [32%] patients), with no unequivocal MOG-IgG1 signal in 2 and only a very weak concomitant MOG-IgG1 signal in the other six samples. By contrast, no significant MOG-IgG3 reactivity was seen in 60 control samples (from 42 healthy individuals and 18 patients with MS). Of note, MOG-IgG3 was also detected in the only patient in our cohort previously diagnosed with MOG-IgA
    Conclusions: In some patients with MOG-EM/MOGAD, MOG-IgG is either exclusively or predominantly MOG-IgG3. Thus, the use of IgG1-specific assays might only partly overcome the current limitations of MOG-IgG testing and-just like H+L- and Fcγ-specific testing-might overlook some genuinely seropositive patients. This would have potentially significant consequences for the management of patients with MOG-EM/MOGAD. Given that IgG3 chiefly detects proteins and is a strong activator of complement and other effector mechanisms, MOG-IgG3 may be involved in the immunopathogenesis of MOG-EM/MOGAD. Studies on the frequency and dynamics as well as the clinical and therapeutic significance of MOG-IgG3 seropositivity are warranted.
    Language English
    Publishing date 2024-04-13
    Publishing country Germany
    Document type Letter
    ZDB-ID 187050-6
    ISSN 1432-1459 ; 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
    ISSN (online) 1432-1459
    ISSN 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
    DOI 10.1007/s00415-024-12285-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Bildgebung des akuten Schlaganfalls

    Ringelstein, E. B.

    Klinische Neurophysiologie

    2008  Volume 39, Issue 2, Page(s) 109

    Language German
    Document type Article
    ZDB-ID 1421558-5
    ISSN 1434-0275
    Database Current Contents Medicine

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  10. Article: Bildgebung des akuten Schlaganfalls

    Ringelstein, E. B.

    Klinische Neurophysiologie

    2008  Volume 39, Issue 02, Page(s) 109–110

    Language German
    Publishing date 2008-01-01
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80107-0
    ISSN 1439-4081 ; 1434-0275 ; 0012-7590
    ISSN (online) 1439-4081
    ISSN 1434-0275 ; 0012-7590
    DOI 10.1055/s-2008-1078715
    Database Thieme publisher's database

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