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  1. Article ; Online: The nailfold dermoscopy findings of patients with atypical haemolytic uremic syndrome.

    Onder, Esra Nagehan Akyol / Gokyayla, Ece / Ermertcan, Aylin Turel / Ertan, Pelin

    Microvascular research

    2023  Volume 148, Page(s) 104548

    Abstract: Introduction: Hemolytic uremic syndrome (HUS) is a severe disease characterized by microangiopathic anemia, thrombocytopenia, and acute renal failure.: Objectives: Atypical HUS (aHUS) that results due to genetic disorders of the alternative ... ...

    Abstract Introduction: Hemolytic uremic syndrome (HUS) is a severe disease characterized by microangiopathic anemia, thrombocytopenia, and acute renal failure.
    Objectives: Atypical HUS (aHUS) that results due to genetic disorders of the alternative complement pathway results in inflammation, endothelial damage, and kidney injury. Therefore, simple and non-invasive tests are needed to evaluate the activity of the disease by assessing the microvascular structure in aHUS.
    Methods: A dermoscope (×10) is an inexpensive and easily portable device used to visualize nailfold capillaries and has high clinical performance and interobserver reliability. In this study, the nailfold capillaries of patients with aHUS who were in remission under eculizumab treatment were examined, and the findings were compared to those of a healthy control group to evaluate disease characteristics.
    Results: All children with aHUS had decreased capillary densities even if they were in remission. This may be indicative of ongoing inflammation and microvascular damage in aHUS.
    Conclusion: A dermoscopy can be used as a screening tool for disease activity in patients with aHUS.
    MeSH term(s) Child ; Humans ; Reproducibility of Results ; Dermoscopy ; Atypical Hemolytic Uremic Syndrome/diagnosis ; Atypical Hemolytic Uremic Syndrome/therapy ; Kidney ; Inflammation
    Language English
    Publishing date 2023-05-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80307-8
    ISSN 1095-9319 ; 0026-2862
    ISSN (online) 1095-9319
    ISSN 0026-2862
    DOI 10.1016/j.mvr.2023.104548
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  2. Article ; Online: Tattoos: Demographics, Motivations, and Regret in Dermatology Patients.

    Altunay, İlknur Kıvanç / Güngör, İlayda Esna / Ozkur, Ezgi / Aydın, Cigdem / Manav, Vildan / Ozden, Hatice Kaya / Ertekin, Sumeyre Seda / Calikoglu, Emel Erdal / Erdoğan, Hilal Kaya / Taskin, Banu / Ficicioglu, S / Memet, Bachar / Gürok, Neşe Göçer / Ermertcan, Aylin Turel

    Indian journal of dermatology

    2023  Volume 67, Issue 6, Page(s) 834

    Abstract: Background: Tattoos are very popular in today's world. Objectives: The aim of this study was to determine the demographics, the characteristics of tattoos, motivations for getting tattoos, tattooing practices and tattoo regret.: Materials and method: ...

    Abstract Background: Tattoos are very popular in today's world. Objectives: The aim of this study was to determine the demographics, the characteristics of tattoos, motivations for getting tattoos, tattooing practices and tattoo regret.
    Materials and method: This multi-centre, cross-sectional study was conducted among. 302 patients attending to the dermatology outpatient clinics and having at least one tattoo. A questionnaire form including all needed data about patients, tattoo characteristics and possible reasons for obtaining tattoos was designed and applied to all participants.
    Results: Of 302 patients, 140 (46,4%) were females and 162 (53,6%) were men. The mean age was28,3 ± 8,1 years (min-max, 16-62) for all study group, 53% of participants (
    Conclusion: Given the rates, tattoo regret is a significant issue and as motivations differ between genders, age groups and other demographic characteristics; tattoos are not just an ink or drawing on the body, but a tool for individuals to express themselves and to construct self-identity. Tattoos have deep symbolic meanings for emotions, and they may be a clue for behavioural patterns of individuals.
    Language English
    Publishing date 2023-03-04
    Publishing country India
    Document type Journal Article
    ZDB-ID 416069-1
    ISSN 1998-3611 ; 0019-5154
    ISSN (online) 1998-3611
    ISSN 0019-5154
    DOI 10.4103/ijd.ijd_879_22
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  3. Article ; Online: Dermoscopic clues of palmoplantar hyperkeratotic eczema and palmoplantar psoriasis: A prospective, comparative study of 90 patients.

    Çetinarslan, Tubanur / Türel Ermertcan, Aylin / Temiz, Peyker

    The Journal of dermatology

    2020  Volume 47, Issue 10, Page(s) 1157–1165

    Abstract: Diagnosis can be difficult in isolated palmar and plantar lesions in patients with psoriasis and eczema. The purpose of our study is to compare the dermoscopic findings in patients with palmoplantar psoriasis and palmoplantar hyperkeratotic eczema. This ... ...

    Abstract Diagnosis can be difficult in isolated palmar and plantar lesions in patients with psoriasis and eczema. The purpose of our study is to compare the dermoscopic findings in patients with palmoplantar psoriasis and palmoplantar hyperkeratotic eczema. This prospective, comparative study included 90 patients histopathologically diagnosed with eczema or psoriasis (35 psoriasis and 55 eczema). The age range was 18-75 years. The most common vessel type was dot vessel in psoriasis. Red globular ring vessels were seen in five patients with psoriasis, but not in any with eczema (P = 0.007). The most common vascular distribution pattern was regular in psoriasis (40%). Patchy vascular pattern was significant in eczema. The most common background color was light red in psoriasis (48.6%) (P < 0.001). Brownish-orange globules were observed in 25.7% of patients with eczema and 5.7% in patients with psoriasis (P = 0.02). There is only one study in the published work about dermoscopy of palmoplantar psoriasis and eczema. In our study, yellow crusts, patchy scale distribution, patchy vascular pattern, yellow scale color, dull red background color and brownish-orange globules were significant in patients with palmoplantar eczema. On the other hand, patients with psoriasis had light red background color, regular vascular distribution pattern and white scale color. We observed globule structures with a pale center and dark peripheral rim only in patients with eczema, which was not identified in previous studies. This globule structure may be a new finding in eczema.
    MeSH term(s) Adolescent ; Adult ; Aged ; Dermoscopy ; Eczema/diagnostic imaging ; Humans ; Keratosis ; Middle Aged ; Prospective Studies ; Psoriasis/diagnostic imaging ; Young Adult
    Language English
    Publishing date 2020-07-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 800103-0
    ISSN 1346-8138 ; 0385-2407
    ISSN (online) 1346-8138
    ISSN 0385-2407
    DOI 10.1111/1346-8138.15487
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  4. Article ; Online: Functional medicine with dermatology insite: A systematic approach for diagnosis and treatment of chronic diseases.

    Gökyayla, Ece / Türel Ermertcan, Aylin / Bilaç, Cemal

    Dermatologic therapy

    2020  Volume 33, Issue 4, Page(s) e13729

    MeSH term(s) Chronic Disease ; Dermatology ; Humans ; Skin Diseases/diagnosis ; Skin Diseases/therapy
    Language English
    Publishing date 2020-06-23
    Publishing country United States
    Document type Letter
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.13729
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  5. Article ; Online: Evaluation of the laboratory parameters in hidradenitis suppurativa: Can we use new inflammatory biomarkers?

    Çetinarslan, Tubanur / Türel Ermertcan, Aylin / Özyurt, Beyhan / Gündüz, Kamer

    Dermatologic therapy

    2021  Volume 34, Issue 2, Page(s) e14835

    Abstract: Hidradenitis suppurativa (HS) is a chronic, recurrent, and debilitating skin disease. Recent studies showed that inflammatory biomarkers, such as neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), Lymphocyte/HDL ratio (LHR), Neutrophil/ ... ...

    Abstract Hidradenitis suppurativa (HS) is a chronic, recurrent, and debilitating skin disease. Recent studies showed that inflammatory biomarkers, such as neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), Lymphocyte/HDL ratio (LHR), Neutrophil/HDL ratio (NHR), and Monocyte/HDL ratio (MHR) are an indicator of inflammatory diseases and may be associated with disease severity and disease activity. To investigate NLR, PLR, LHR, NHR, and MHR in HS patients. In addition, to compare erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), complete blood count, leukocyte profile, and biochemical parameters between the control and the patient group. Clinical and biochemical data of patients and healthy subjects were collected from medical records, retrospectively. In total, 166 patients with HS and 124 control subjects were included. We found no significant difference in NLR (P = .207) and PLR (P = .257). LHR (P < .001), NHR (P < .001), and MHR (P < .001) were significantly higher in the patient group. No positive correlation was found between any of these markers and disease severity according to Hurley staging system. However, MCV (Mean corpuscular volume), RDW (Red cell distribution width), and CRP showed a significant positive correlation with disease severity. Among these markers, only MHR was positively correlated with disease duration. Our study shows that CRP still maintains its value for HS patients compared to new inflammation markers. Unlike the studies in other inflammatory diseases, no significant relationship was found with most of these inflammatory parameters. MHR may be more useful in patients with HS as an indicator of inflammation compared to other parameters.
    MeSH term(s) Biomarkers ; Blood Sedimentation ; Hidradenitis Suppurativa/diagnosis ; Humans ; Laboratories ; Neutrophils ; Retrospective Studies
    Chemical Substances Biomarkers
    Language English
    Publishing date 2021-02-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.14835
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  6. Article ; Online: Amlodipine-induced generalized fixed drug eruption clinically mimicking mycosis fungoides.

    Çetinarslan, Tubanur / Ermertcan, Aylin Türel / Temiz, Peyker

    Dermatologic therapy

    2021  Volume 34, Issue 2, Page(s) e14775

    MeSH term(s) Amlodipine/adverse effects ; Diagnosis, Differential ; Drug Eruptions/diagnosis ; Drug Eruptions/etiology ; Humans ; Mycosis Fungoides/diagnosis ; Mycosis Fungoides/drug therapy ; Skin Neoplasms/diagnosis ; Skin Neoplasms/drug therapy
    Chemical Substances Amlodipine (1J444QC288)
    Language English
    Publishing date 2021-01-17
    Publishing country United States
    Document type Letter
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.14775
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  7. Article ; Online: A rare vasculitis type in a patient with acute myeloblastic leukemia: Annular leukocytoclastic vasculitis as a paraneoplastic syndrome?

    Çetinarslan, Tubanur / Türel Ermertcan, Aylin / Aydoğdu, İsmet / Temiz, Peyker

    Dermatologic therapy

    2020  Volume 33, Issue 6, Page(s) e14080

    MeSH term(s) Humans ; Leukemia, Myeloid, Acute/complications ; Leukemia, Myeloid, Acute/diagnosis ; Leukemia, Myeloid, Acute/drug therapy ; Paraneoplastic Syndromes/diagnosis ; Paraneoplastic Syndromes/etiology ; Vasculitis ; Vasculitis, Leukocytoclastic, Cutaneous/diagnosis ; Vasculitis, Leukocytoclastic, Cutaneous/drug therapy
    Language English
    Publishing date 2020-08-14
    Publishing country United States
    Document type Letter
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.14080
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  8. Article ; Online: The reliability of tuberculin skin test in the diagnosis of latent tuberculosis infection in psoriasis patients: A case-control study.

    Sürücüoğlu, Süheyla / Türel Ermertcan, Aylin / Çetinarslan, Tubanur / Özkütük, Nuri

    Dermatologic therapy

    2020  Volume 33, Issue 4, Page(s) e13496

    Abstract: Tuberculin skin test (TST), which is used in the diagnosis of latent tuberculosis infection, may cause Koebner's phenomenon and false-positive results in psoriasis patients. The purpose of this study is to compare TST with QuantiFERON-TB Gold Plus (QFT- ... ...

    Abstract Tuberculin skin test (TST), which is used in the diagnosis of latent tuberculosis infection, may cause Koebner's phenomenon and false-positive results in psoriasis patients. The purpose of this study is to compare TST with QuantiFERON-TB Gold Plus (QFT-plus) test in psoriasis patients and to determine the effects of psoriasis on TST results. Ninety-two psoriasis patients and 30 control subjects were included in the study. QFT-plus test, TST, and prick test to distinguish the increase of induration because of the skin trauma were performed on both groups. The demographics, risk factors for latent tuberculosis infection, BCG vaccination history, Koebner's history, psoriasis severity, and treatment history of the patients were recorded. The effects of these variables on test results were investigated by comparing those with control group. The criteria of National Tuberculosis Diagnosis and Treatment Guidelines were used in the evaluation of test results, and threshold value of positivity for TST was taken as 10 mm in BCG-vaccinated patients who are planned to start biological treatment. Prick test results were negative in the control group. There was no significant relation between the results of prick test and TST induration diameters in the patient group. Although TST positivity was significantly higher in patients (62%) compared with control group (33%), QFT-plus test results were not statistically different between two groups. Agreement between two tests was determined to be low in patient group with 48% (K = 0.1), and it was determined to be moderate with 77% in control group (K = 0.4). QFT-plus test was found to be negative in 46 of 57 TST-positive patients (80.7%) in patient group. It was determined in both groups that vaccination did not have any effect on test results. When threshold value was lowered to 5 mm in patient group without considering BCG reaction, the number of TST-positive patients increased from 57 to 65. Mean TST induration diameter was 10 mm and 14 mm in cases with mild and moderate to severe clinical manifestation, respectively (P = .04). However, no effect of disease period and treatment was determined on both test results. TST positivity was higher in psoriasis patients compared with control group. It was considered due to the increased reaction of the skin to mycobacterial antigens rather than the Koebner's response. Although TST results were not affected by BCG, it was concluded that a 10-mm threshold value of positivity was a suitable approach in order to reduce the number of patients receiving unnecessary preventive treatment in patients who are considered to initiate biologic agents. Furthermore, it was also concluded that QFT-plus test may be preferred in psoriasis patients since it is applied in vitro and its specificity is higher and not affected by disease severity.
    MeSH term(s) Case-Control Studies ; Humans ; Latent Tuberculosis/diagnosis ; Psoriasis/diagnosis ; Reproducibility of Results ; Tuberculin Test
    Language English
    Publishing date 2020-05-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.13496
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  9. Article ; Online: Mycosis fungoides mimicking pigmented purpuric dermatosis.

    Gökyayla, Ece / Çetinarslan, Tubanur / Temiz, Peyker / Türel Ermertcan, Aylin

    Dermatologic therapy

    2020  Volume 33, Issue 6, Page(s) e14062

    MeSH term(s) Humans ; Mycosis Fungoides/diagnosis ; Pigmentation Disorders ; Purpura/diagnosis ; Skin Neoplasms/diagnosis
    Language English
    Publishing date 2020-08-13
    Publishing country United States
    Document type Letter
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.14062
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  10. Article ; Online: Urticarial Vasculitis Successfully Treated With Omalizumab.

    Ermertcan, Aylin Türel / Aktaş, Ayşe / Öztürk, Ferdi / Temiz, Peyker

    Cutis

    2021  Volume 107, Issue 5, Page(s) E19–E21

    MeSH term(s) Humans ; Omalizumab/therapeutic use ; Peripheral Vascular Diseases ; Urticaria/diagnosis ; Urticaria/drug therapy ; Vasculitis/diagnosis ; Vasculitis/drug therapy ; Vasculitis, Leukocytoclastic, Cutaneous/diagnosis ; Vasculitis, Leukocytoclastic, Cutaneous/drug therapy
    Chemical Substances Omalizumab (2P471X1Z11)
    Language English
    Publishing date 2021-07-08
    Publishing country United States
    Document type Letter
    ZDB-ID 391840-3
    ISSN 2326-6929 ; 0011-4162 ; 0151-9522
    ISSN (online) 2326-6929
    ISSN 0011-4162 ; 0151-9522
    DOI 10.12788/cutis.0272
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