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  1. Article ; Online: Trials and Tribulations in Rare Cancer Clinical Research.

    Maki, Robert G

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2024  Volume 42, Issue 8, Page(s) 865–867

    MeSH term(s) Humans ; Neoplasms/therapy
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Editorial
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.23.02137
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1847: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 650: Show issues

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  2. Article ; Online: Flashback Foreword: Single-Agent Anti-Programmed Cell Death Protein 1 Therapy for Refractory Solid Tumors.

    Maki, Robert G

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2023  Volume 41, Issue 4, Page(s) 713–714

    MeSH term(s) Humans ; Neoplasms/drug therapy ; Neoplasms/pathology ; Cell Death ; B7-H1 Antigen/therapeutic use
    Chemical Substances B7-H1 Antigen
    Language English
    Publishing date 2023-01-27
    Publishing country United States
    Document type Editorial
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.22.02437
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1847: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 650: Show issues

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  3. Article ; Online: Flashback Foreword: Kinase Mutations and Imatinib Response in Patients With Metastatic GI Stromal Tumor.

    Maki, Robert G

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2023  Volume 41, Issue 31, Page(s) 4827–4828

    MeSH term(s) Humans ; Imatinib Mesylate/therapeutic use ; Gastrointestinal Stromal Tumors/drug therapy ; Gastrointestinal Stromal Tumors/genetics ; Gastrointestinal Stromal Tumors/surgery ; Antineoplastic Agents/therapeutic use ; Mutation ; Protein Kinase Inhibitors/therapeutic use ; Proto-Oncogene Proteins c-kit/genetics
    Chemical Substances Imatinib Mesylate (8A1O1M485B) ; Antineoplastic Agents ; Protein Kinase Inhibitors ; Proto-Oncogene Proteins c-kit (EC 2.7.10.1)
    Language English
    Publishing date 2023-10-25
    Publishing country United States
    Document type Editorial
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.23.00213
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1847: Show issues Location:
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  4. Article ; Online: Flashback Foreword: Carboplatin Dosage Based on Renal Function.

    Maki, Robert G / Cannistra, Stephen A

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2023  Volume 41, Issue 28, Page(s) 4451–4452

    MeSH term(s) Humans ; Carboplatin/adverse effects ; Antineoplastic Agents/adverse effects ; Kidney/physiology
    Chemical Substances Carboplatin (BG3F62OND5) ; Antineoplastic Agents
    Language English
    Publishing date 2023-09-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.22.02865
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)
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  5. Article ; Online: Flashback Foreword: Prognostic Factors in Osteosarcoma.

    Maki, Robert G / Schwartz, Gary K

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2023  Volume 41, Issue 27, Page(s) 4321–4322

    MeSH term(s) Humans ; Prognosis ; Osteosarcoma/therapy ; Bone Neoplasms/therapy
    Language English
    Publishing date 2023-09-13
    Publishing country United States
    Document type Editorial
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.22.02860
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1847: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  6. Article ; Online: The Weighted Toxicity Score: Confirmation of a Simple Metric to Communicate Toxicity in Randomized Trials of Systemic Cancer Therapy.

    Jordan, Jacob / Maki, Robert G

    The oncologist

    2023  Volume 29, Issue 1, Page(s) 67–74

    Abstract: Introduction: FDA's Project Optimus was developed in part to better identify appropriate dose and schedule of cancer therapeutics. The tabular method to summarize patients' maximum toxicity in a clinical trial does not allow for ready comparison to the ... ...

    Abstract Introduction: FDA's Project Optimus was developed in part to better identify appropriate dose and schedule of cancer therapeutics. The tabular method to summarize patients' maximum toxicity in a clinical trial does not allow for ready comparison to the treatment's benefit. In this manuscript, we apply a simple tool, the weighted toxicity score (WTS), to trials involving lung cancer immunotherapy and chemotherapy, as well as those cited in a recent publication as examples of trials that represent successful reduction of the appropriate dose of anti-cancer agents.
    Methods: PubMed was queried for randomized controlled trials of therapy involving immune checkpoint inhibitors in lung cancer. Trial data from studies highlighting initial success with dose adjustments after FDA approval also were assembled and analyzed according to the WTS procedure described previously, compared to clinical outcomes data.
    Results: The WTS provided, with the clinical outcome(s), a data pair that leads to easy interpretation of the expected benefit versus relative toxicity of studies involving immunotherapy or chemoimmunotherapy in lung cancers. The WTS was consistent with the conclusions of the primary studies, helping to quantitate the toxicity difference between treatments in a previously unavailable way.
    Conclusion: The WTS provides a tool to show the cost in toxicity of therapy in a randomized clinical trial, with applicability to studies involving chemotherapy, immunotherapy, or kinase-directed therapy. Inclusion of a running tally of WTS during conduct of a trial could serve as one means to adjust dosing or to provide feedback during data safety monitoring of a clinical trial.
    MeSH term(s) Humans ; Randomized Controlled Trials as Topic ; Antineoplastic Agents/adverse effects ; Immunotherapy/adverse effects ; Immunotherapy/methods ; Lung Neoplasms/drug therapy
    Chemical Substances Antineoplastic Agents
    Language English
    Publishing date 2023-07-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 1409038-7
    ISSN 1549-490X ; 1083-7159
    ISSN (online) 1549-490X
    ISSN 1083-7159
    DOI 10.1093/oncolo/oyad192
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4845: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 494: Show issues

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  7. Book ; Conference proceedings: Sarcomas and gastrointestinal stromal tumors

    Maki, Robert G.

    presentations from the 2008 European Society for Medical Oncology international symposium ; [Milan, Italy on May 13 and 14, 2008]

    (Seminars in oncology ; 36,4)

    2009  

    Institution European Society for Medical Oncology
    Author's details Robert G. Maki ... guest ed
    Series title Seminars in oncology ; 36,4
    Collection
    Language English
    Size S. 289 - 371 : Ill., graph. Darst.
    Publisher Saunders/Elsevier
    Publishing place New York, NY
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT016040882
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    Zs A 1348 -36- not available for loan Zeitschriften-Lesesaal

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  8. Article ; Online: Disparities in Receipt of Smoking Cessation Assistance Within the US.

    Maki, Kristin G / Volk, Robert J

    JAMA network open

    2022  Volume 5, Issue 6, Page(s) e2215681

    MeSH term(s) Behavior Therapy ; Humans ; Smoking Cessation ; Surveys and Questionnaires
    Language English
    Publishing date 2022-06-01
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2022.15681
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Lenalidomide and the Expanding Toolkit to Manage Kaposi Sarcoma.

    Henry, David H / Maki, Robert G

    Clinical cancer research : an official journal of the American Association for Cancer Research

    2022  Volume 28, Issue 12, Page(s) 2485–2487

    Abstract: Lenalidomide recently was shown to have clinical activity in patients with human immunodeficiency virus-associated Kaposi sarcoma. Immunomodulatory imine drugs thus provide another tool in the treatment of this challenging neoplasm. See related article ... ...

    Abstract Lenalidomide recently was shown to have clinical activity in patients with human immunodeficiency virus-associated Kaposi sarcoma. Immunomodulatory imine drugs thus provide another tool in the treatment of this challenging neoplasm. See related article by Reid et al., p. 2646.
    MeSH term(s) HIV Infections/complications ; HIV Infections/drug therapy ; Humans ; Lenalidomide/therapeutic use ; Sarcoma, Kaposi/diagnosis ; Sarcoma, Kaposi/drug therapy
    Chemical Substances Lenalidomide (F0P408N6V4)
    Language English
    Publishing date 2022-05-04
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1225457-5
    ISSN 1557-3265 ; 1078-0432
    ISSN (online) 1557-3265
    ISSN 1078-0432
    DOI 10.1158/1078-0432.CCR-22-0884
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4223: Show issues Location:
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  10. Book: Sarcomas

    Maki, Robert G.

    (Hematology oncology clincis of North America ; 19,3)

    2005  

    Author's details guest ed. Robert G. Maki
    Series title Hematology oncology clincis of North America ; 19,3
    Hematology, oncology clinics of North America
    Collection Hematology, oncology clinics of North America
    Keywords Sarkom
    Language English
    Size XII S., S. 427 - 596 : Ill., graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT014446413
    ISBN 1-4160-2774-2 ; 978-1-4160-2774-4
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Se 1077 -19,3- verfügbar in Königswinter Königswinter

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