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  1. Article ; Online: Measuring the monetization strategies of websites with application to pro- and anti-vaccine communities.

    Broniatowski, David A / Greene, Kevin T / Pisharody, Nilima / Rogers, Daniel J / Shapiro, Jacob N

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 15964

    Abstract: Anti-vaccine content and other kinds of misinformation are hypothesized to be more heavily monetized than other kinds of online content. We test this hypothesis by applying several novel and scalable measures of website monetization strategies to more ... ...

    Abstract Anti-vaccine content and other kinds of misinformation are hypothesized to be more heavily monetized than other kinds of online content. We test this hypothesis by applying several novel and scalable measures of website monetization strategies to more than 400,000 links shared by 261 anti-vaccine Facebook pages and 190 pro-vaccine ones. Contrary to expectations, websites promoted in pro-vaccine venues do more to monetize attention than those promoted in anti-vaccine venues. This is a consequence of how intensely monetized news websites are-pro-vaccine venues share more links to news. The specific news sites shared by anti-vaccine venues are rated less credible by fact-checking organizations, but we find little substantive difference in their monetization strategies. These results emphasize the need to interpret measures of monetization within the context of the broader "attention economy".
    MeSH term(s) Humans ; Vaccines ; Internet/economics ; Vaccination Refusal ; Vaccination ; Social Media/economics
    Chemical Substances Vaccines
    Language English
    Publishing date 2023-09-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-43061-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Variations in Treatment and Costs for Distal Radius Fractures in Patients Over 55 Years of Age: A Population-Based Study.

    Shapiro, Lauren M / Xiao, Michelle / Zhuang, Thompson / Ruch, David S / Richard, Marc J / Kamal, Robin N

    Journal of hand and microsurgery

    2022  Volume 15, Issue 5, Page(s) 351–357

    Abstract: ... ...

    Abstract Objective
    Language English
    Publishing date 2022-07-05
    Publishing country United States
    Document type Journal Article
    ISSN 0974-3227
    ISSN 0974-3227
    DOI 10.1055/s-0042-1749460
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Use of a Virtual Multi-Disciplinary Clinic for the Treatment of Post-COVID-19 Patients.

    Rahamim-Cohen, Daniella / Kertes, Jennifer / Feldblum, Ilana / Shamir-Stein, Naama / Shapiro Ben David, Shirley

    Healthcare (Basel, Switzerland)

    2024  Volume 12, Issue 3

    Abstract: Post-COVID-19 has been recognized as possibly affecting millions of people worldwide. In order to optimize care and ensure equality, we established a multidisciplinary virtual Post-COVID-19 clinic (VPCC) within Maccabi Healthcare Services, the second ... ...

    Abstract Post-COVID-19 has been recognized as possibly affecting millions of people worldwide. In order to optimize care and ensure equality, we established a multidisciplinary virtual Post-COVID-19 clinic (VPCC) within Maccabi Healthcare Services, the second largest HMO in Israel. This study aims to describe the structure, process and patient satisfaction with this clinic. The multidisciplinary team consisted of physicians, physiotherapists, social workers, occupational therapists and dieticians. Patient entry was to be at least four weeks after COVID-19 infection. A patient satisfaction survey was carried out 7-8 months after the clinic was closed. Demographic data were collected and compared to the general Maccabi COVID-19 population. The clinic treated 1614 patients, aged 16-91, over a period of 18 months. In total, 679 family physicians referred patients. In comparison to the general COVID-19 population, a higher percentage of the VPCC patients lived in the periphery of Israel, South (14.9% compared to 17.8%) and North (17.1% compared to 18.2%). In total, 249 patients answered the survey, and of them, 75% were highly satisfied with the medical care of the physician in the VPCC. A total of 54% of respondents would have preferred a face-to-face consultation, but 50% felt that communication was good in the virtual mode. In conclusion, the VPCC provided a dedicated service for patients, and the virtual format made it equally accessible to all parts of the country.
    Language English
    Publishing date 2024-02-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare12030376
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Buprenorphine for Long-Term Chronic Pain Management: Still Looking for the Evidence.

    Schatman, Michael E / Shapiro, Hannah / DiBenedetto, David J

    Annals of internal medicine

    2020  Volume 172, Issue 4, Page(s) 293–294

    MeSH term(s) Analgesics, Opioid ; Buprenorphine ; Chronic Pain ; Humans ; Opioid-Related Disorders
    Chemical Substances Analgesics, Opioid ; Buprenorphine (40D3SCR4GZ)
    Language English
    Publishing date 2020-02-18
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/L19-0683
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.178/2: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Models of Renal Cell Carcinoma Used to Investigate Molecular Mechanisms and Develop New Therapeutics.

    Shapiro, Daniel D / Virumbrales-Muñoz, Maria / Beebe, David J / Abel, E Jason

    Frontiers in oncology

    2022  Volume 12, Page(s) 871252

    Abstract: Modeling renal cell carcinoma is critical to investigating tumor biology and therapeutic mechanisms. Multiple systems have been developed to represent critical components of the tumor and its surrounding microenvironment. ... ...

    Abstract Modeling renal cell carcinoma is critical to investigating tumor biology and therapeutic mechanisms. Multiple systems have been developed to represent critical components of the tumor and its surrounding microenvironment. Prominent
    Language English
    Publishing date 2022-04-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2022.871252
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Activators of the Anticipatory Unfolded Protein Response with Enhanced Selectivity for Estrogen Receptor Positive Breast Cancer.

    Boudreau, Matthew W / Mulligan, Michael P / Shapiro, David J / Fan, Timothy M / Hergenrother, Paul J

    Journal of medicinal chemistry

    2022  Volume 65, Issue 5, Page(s) 3894–3912

    Abstract: Approximately 75% of breast cancers are estrogen receptor alpha-positive (ERα+), and targeting ERα directly with ERα antagonists/degraders or indirectly with aromatase inhibitors is a successful therapeutic strategy. However, such treatments are rarely ... ...

    Abstract Approximately 75% of breast cancers are estrogen receptor alpha-positive (ERα+), and targeting ERα directly with ERα antagonists/degraders or indirectly with aromatase inhibitors is a successful therapeutic strategy. However, such treatments are rarely curative and development of resistance is universal. We recently reported
    MeSH term(s) Female ; Humans ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Estrogen Receptor alpha/metabolism ; Receptors, Estrogen/metabolism ; Unfolded Protein Response
    Chemical Substances Estrogen Receptor alpha ; Receptors, Estrogen
    Language English
    Publishing date 2022-01-26
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 218133-2
    ISSN 1520-4804 ; 0022-2623
    ISSN (online) 1520-4804
    ISSN 0022-2623
    DOI 10.1021/acs.jmedchem.1c01730
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 151: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MB 1: Show issues

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  7. Article ; Online: Potential for Allergic Contact Dermatitis in Popular Hair Care Practices and Ingredients.

    Karim, Maria / Klein, Elizabeth J / Nohria, Ambika / Taiwo, Dolly / Adotama, Prince / Cohen, David / Shapiro, Jerry / Milam, Emily / Lo Sicco, Kristen

    Dermatitis : contact, atopic, occupational, drug

    2023  Volume 34, Issue 6, Page(s) 484–491

    Abstract: The incidence of allergic contact dermatitis (ACD) due to personal care products is rising in parallel with increasing product availability and consumer interest. Hair products specifically represent a significant source of potential allergens, including ...

    Abstract The incidence of allergic contact dermatitis (ACD) due to personal care products is rising in parallel with increasing product availability and consumer interest. Hair products specifically represent a significant source of potential allergens, including preservatives, surfactants, emulsifiers, fragrances, adhesives, and dyes. ACD due to hair care products can present as dermatitis in the distinctive "rinse-off" distribution, involving the neck, eyelids, and lateral face in addition to the scalp. Herein, the authors review ingredients in hair care products that can cause ACD and practical tips for allergen identification.
    MeSH term(s) Humans ; Dermatitis, Allergic Contact/diagnosis ; Dermatitis, Allergic Contact/etiology ; Dermatitis, Allergic Contact/epidemiology ; Allergens/adverse effects ; Cosmetics ; Hair ; Hair Preparations/adverse effects
    Chemical Substances Allergens ; Cosmetics ; Hair Preparations
    Language English
    Publishing date 2023-06-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2144723-8
    ISSN 2162-5220 ; 1532-8163 ; 1710-3568
    ISSN (online) 2162-5220 ; 1532-8163
    ISSN 1710-3568
    DOI 10.1089/derm.2023.0045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3680: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Cyclosporine A Does Not Mitigate Liver Ischemia/Reperfusion Injury in an Ex Vivo Porcine Model of Donation After Circulatory Death.

    Hefler, Joshua / Hatami, Sanaz / Thiesen, Aducio / Wagner, Mitchell J / Mainardi, Guilherme / Himmat, Sayed / Karvellas, Constantine J / Bigam, David L / Freed, Darren H / Shapiro, A M James

    Annals of transplantation

    2024  Volume 29, Page(s) e941054

    Abstract: BACKGROUND Ischemia/reperfusion injury (IRI) is an inherent problem in organ transplantation, owing to the obligate period of ischemia that organs must endure. Cyclosporine A (CsA), though better know as an immunosuppressant, has been shown to mitigate ... ...

    Abstract BACKGROUND Ischemia/reperfusion injury (IRI) is an inherent problem in organ transplantation, owing to the obligate period of ischemia that organs must endure. Cyclosporine A (CsA), though better know as an immunosuppressant, has been shown to mitigate warm IRI in a variety of organ types, including the liver. However, there is little evidence for CsA in preventing hepatic IRI in the transplant setting. MATERIAL AND METHODS In the present study, we tested the effect of CsA on hepatic IRI in a large-animal ex vivo model of donation after circulatory death (DCD). Porcine donors were pre-treated with either normal saline control or 20 mg/kg of CsA. Animals were subject to either 45 or 60 minutes of warm ischemia before hepatectomy, followed by 2 or 4 hours of cold storage prior to reperfusion on an ex vivo circuit. Over the course of a 12-hour perfusion, perfusion parameters were recorded and perfusate samples and biopsies were taken at regular intervals. RESULTS Peak perfusate lactate dehydrogenase was significantly decreased in the lower-ischemia group treated with CsA compared to the untreated group (4220 U/L [3515-5815] vs 11 305 [10 100-11 674]; P=0.023). However, no difference was seen between controls and CsA-treated groups on other parameters in perfusate alanine or asparagine aminotransferase (P=0.912, 0.455, respectively). Correspondingly, we found no difference on midpoint histological injury score (P=0.271). CONCLUSIONS We found minimal evidence that CsA is protective against hepatic IRI in our DCD model.
    MeSH term(s) Swine ; Animals ; Cyclosporine/pharmacology ; Cyclosporine/therapeutic use ; Liver/pathology ; Reperfusion Injury/pathology ; Perfusion ; Reperfusion ; Organ Preservation/methods
    Chemical Substances Cyclosporine (83HN0GTJ6D)
    Language English
    Publishing date 2024-01-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1484710-3
    ISSN 2329-0358 ; 1425-9524
    ISSN (online) 2329-0358
    ISSN 1425-9524
    DOI 10.12659/AOT.941054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5093: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Societal Reentry of Prison Inmates With Mental Illness: Obstacles, Programs, and Best Practices.

    Galletta, Esther / Fagan, Thomas J / Shapiro, David / Walker, Lenore E

    Journal of correctional health care : the official journal of the National Commission on Correctional Health Care

    2021  Volume 27, Issue 1, Page(s) 58–65

    Abstract: Societal reentry from prison presents a wide array of extreme challenges to inmates attempting to reintegrate with society. This process is significantly more daunting for inmates suffering from mental illness for several reasons. This paper examines the ...

    Abstract Societal reentry from prison presents a wide array of extreme challenges to inmates attempting to reintegrate with society. This process is significantly more daunting for inmates suffering from mental illness for several reasons. This paper examines the reentry process for inmates with mental illness. Three sample reentry programs (Forensic Assertive Community Treatment, Critical Time Intervention, and Thresholds' Prison Aftercare Program) that were developed for inmates with mental illness are discussed along with research testifying to the effectiveness of these programs. Finally, components that would comprise an ideal prison reentry program for mentally ill inmates are outlined, which include a three-phase structure and a focus on preparing both inmates and communities for the reentry process.
    MeSH term(s) Humans ; Mental Disorders/therapy ; Mentally Ill Persons ; Prisoners ; Prisons
    Language English
    Publishing date 2021-02-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2233559-6
    ISSN 1940-5200 ; 1078-3458
    ISSN (online) 1940-5200
    ISSN 1078-3458
    DOI 10.1089/jchc.19.04.0032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Transcriptional Profile of Exercise-Induced Protection Against Relapse to Cocaine Seeking in a Rat Model.

    Towers, Eleanor Blair / Shapiro, Daniel A / Abel, Jean M / Bakhti-Suroosh, Anousheh / Kupkova, Kristyna / Auble, David T / Grant, Patrick A / Lynch, Wendy J

    Biological psychiatry global open science

    2023  Volume 3, Issue 4, Page(s) 734–745

    Abstract: Background: Exercise has shown promise as a treatment for cocaine use disorder; however, the mechanism underlying its efficacy has remained elusive.: Methods: We used a rat model of relapse (cue-induced reinstatement) and exercise (wheel running, 2 ... ...

    Abstract Background: Exercise has shown promise as a treatment for cocaine use disorder; however, the mechanism underlying its efficacy has remained elusive.
    Methods: We used a rat model of relapse (cue-induced reinstatement) and exercise (wheel running, 2 hours/day) coupled with RNA sequencing to establish transcriptional profiles associated with the protective effects of exercise (during early withdrawal [days 1-7] or throughout withdrawal [days 1-14]) versus noneffective exercise (during late withdrawal [days 8-14]) against cocaine-seeking and sedentary conditions.
    Results: As expected, cue-induced cocaine seeking was highest in the sedentary and late-withdrawal exercise groups; both groups also showed upregulation of a
    Conclusions: These findings provide a rich resource for future studies aimed at manipulating these molecular networks to better understand how exercise decreases cocaine seeking.
    Language English
    Publishing date 2023-02-03
    Publishing country United States
    Document type Journal Article
    ISSN 2667-1743
    ISSN (online) 2667-1743
    DOI 10.1016/j.bpsgos.2023.01.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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