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  1. Article: Why did humans surpass all other primates? Are our brains so different? Part 2.

    Nitrini, Ricardo

    Dementia & neuropsychologia

    2024  Volume 18, Page(s) e20240087P2

    Abstract: The second part of this review is an attempt to explain why ... ...

    Abstract The second part of this review is an attempt to explain why only
    Language English
    Publishing date 2024-04-15
    Publishing country Brazil
    Document type Journal Article ; Review
    ISSN 1980-5764
    ISSN 1980-5764
    DOI 10.1590/1980-5764-DN-2024-0087P2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Why did humans surpass all other primates? Are our brains so different? Part 1.

    Nitrini, Ricardo

    Dementia & neuropsychologia

    2024  Volume 18, Page(s) e20240087P1

    Abstract: This review is based on a conference presented in June 2023. Its main objective is to explain the cognitive differences between humans and non-human primates (NHPs) focusing on characteristics of their brains. It is based on the opinion of a clinical ... ...

    Abstract This review is based on a conference presented in June 2023. Its main objective is to explain the cognitive differences between humans and non-human primates (NHPs) focusing on characteristics of their brains. It is based on the opinion of a clinical neurologist and does not intend to go beyond an overview of this complex topic. As language is the main characteristic differentiating humans from NHPs, this review is targeted at their brain networks related to language. NHPs have rudimentary forms of language, including primitive lexical/semantic signs. Humans have a much broader lexical/semantic repertory, but syntax is the most important characteristic, which is probably unique to
    Language English
    Publishing date 2024-04-15
    Publishing country Brazil
    Document type Journal Article ; Review
    ISSN 1980-5764
    ISSN 1980-5764
    DOI 10.1590/1980-5764-DN-2024-0087P1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The past, present and future of Alzheimer's disease - part 1: the past.

    Nitrini, Ricardo

    Arquivos de neuro-psiquiatria

    2023  Volume 81, Issue 12, Page(s) 1070–1076

    Abstract: Background:  Alzheimer's disease (AD) was described in 1907, and since then it changed from a relatively rare condition to one of the most prevalent diseases.: Objective:  To describe the evolution of the notions of dementias and AD, and to ... ...

    Title translation O passado, presente e futuro da doença de Alzheimer – parte 1: o passado.
    Abstract Background:  Alzheimer's disease (AD) was described in 1907, and since then it changed from a relatively rare condition to one of the most prevalent diseases.
    Objective:  To describe the evolution of the notions of dementias and AD, and to investigate the reasons for the increase in scientific interest in AD.
    Methods:  A historical analysis was carried out on knowledge about dementia, the site of mental activity, the relationships between brain diseases and mental activity, and on the advances in research about AD, since its discovery until the publication of the amyloid cascade hypothesis in 1992. A search was carried out in the National Library of Medicine (PubMed) for scientific articles that included the terms dementia or AD over 50 years, from 1972 to 2021.
    Results:  The scientific research on AD increased from 615 papers with the term AD in the first decade (1972-1981), to 100,028 papers in the last decade (2012-2021): an increase of 162.6 times whereas publications with the term dementia increased 28.6 times in the same period. In the 1960s and 1970s, a consensus was reached that AD is responsible for the majority of cases of dementia previously known as senile dementia. In the 1980s, beta-amyloid peptide was identified in the core of the senile plaque, hyperphosphorylated tau protein was found in neurofibrillary tangles, and a mutation was discovered in a hereditary form of AD.
    Conclusion:  The expansion of the concept of AD to include senile dementia, and the discoveries that occurred in the 1980s greatly expanded research in AD.
    MeSH term(s) Humans ; Alzheimer Disease/genetics ; tau Proteins/metabolism ; Neurofibrillary Tangles/metabolism ; Amyloid beta-Peptides/metabolism ; Brain/metabolism
    Chemical Substances tau Proteins ; Amyloid beta-Peptides
    Language English
    Publishing date 2023-12-29
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 418916-4
    ISSN 1678-4227 ; 0004-282X
    ISSN (online) 1678-4227
    ISSN 0004-282X
    DOI 10.1055/s-0043-1777722
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui I Zs.239: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Training of neurologists for the 21st century: cultural and professional skills.

    Nitrini, Ricardo

    Arquivos de neuro-psiquiatria

    2022  Volume 80, Issue 5 Suppl 1, Page(s) 1–6

    Abstract: Training of neurologists for the near future is a challenge due to the likely advances in neuroscientific methods, which will change much of our knowledge on diagnosis and treatment of neurological diseases.: Objective: to comment on what may be more ... ...

    Abstract Training of neurologists for the near future is a challenge due to the likely advances in neuroscientific methods, which will change much of our knowledge on diagnosis and treatment of neurological diseases.
    Objective: to comment on what may be more likely to be a constant in the very near future and to recommend how to prepare the neurologist for the 21st century.
    Methods: through a critical review of recent articles on the teaching of Neurology, to present a personal view on the subject.
    Results: Diagnostic methods and therapeutic resources in Neurology will be greatly improved, but the central core of teaching young neurologists will continue to be the clinical/anatomical correlation. The neurologist must be prepared to be the primary physician in the care of patients with neurological disorders, although the roles of consultant and clinical neuroscientist must also be considered. In addition to technical knowledge, the neurologist must be prepared to discuss not only distressing issues related to the specialty, such as the risks of genetic diseases for family members of their patients, the inexorable progression of some diseases and the need for palliative care, but also problems not directly related to Neurology that cause anxiety and depression in the patient or that are the main reason for the initial consultation.
    Conclusion: neurology will be an even more important area of medicine and the neurologist must be well prepared to be the primary doctor to diagnose, treat and follow the patient with neurological disorders. In addition to technical knowledge, training in doctor-patient relations should be highlighted.
    MeSH term(s) Anxiety ; Humans ; Nervous System Diseases/diagnosis ; Nervous System Diseases/therapy ; Neurologists ; Neurology/history
    Language English
    Publishing date 2022-08-17
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 418916-4
    ISSN 1678-4227 ; 0004-282X
    ISSN (online) 1678-4227
    ISSN 0004-282X
    DOI 10.1590/0004-282X-ANP-2022-S104
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui I Zs.239: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: The past, present and future of Alzheimer's disease – part 1: the past

    Nitrini, Ricardo

    Arquivos de Neuro-Psiquiatria

    2023  Volume 81, Issue 12, Page(s) 1070–1076

    Abstract: Background: Alzheimer's disease (AD) was described in 1907, and since then it changed from a relatively rare condition to one of the most prevalent diseases.: Objective: To describe the evolution of the notions of dementias and AD, and to investigate ...

    Abstract Background: Alzheimer's disease (AD) was described in 1907, and since then it changed from a relatively rare condition to one of the most prevalent diseases.
    Objective: To describe the evolution of the notions of dementias and AD, and to investigate the reasons for the increase in scientific interest in AD.
    Methods: A historical analysis was carried out on knowledge about dementia, the site of mental activity, the relationships between brain diseases and mental activity, and on the advances in research about AD, since its discovery until the publication of the amyloid cascade hypothesis in 1992. A search was carried out in the National Library of Medicine (PubMed) for scientific articles that included the terms dementia or AD over 50 years, from 1972 to 2021.
    Results: The scientific research on AD increased from 615 papers with the term AD in the first decade (1972-1981), to 100,028 papers in the last decade (2012-2021): an increase of 162.6 times whereas publications with the term dementia increased 28.6 times in the same period. In the 1960s and 1970s, a consensus was reached that AD is responsible for the majority of cases of dementia previously known as senile dementia. In the 1980s, beta-amyloid peptide was identified in the core of the senile plaque, hyperphosphorylated tau protein was found in neurofibrillary tangles, and a mutation was discovered in a hereditary form of AD.
    Conclusion: The expansion of the concept of AD to include senile dementia, and the discoveries that occurred in the 1980s greatly expanded research in AD.
    Keywords History ; Alzheimer Disease ; Plaque Amyloid ; Neurofibrillary Tangles ; Amyloid beta-Peptides ; Alois Alzheimer ; Oskar Fischer ; Emil Kraepelin ; História ; Doença de Alzheimer ; Placa Amiloide ; Emaranhados Neurofibrilares ; Peptídeos beta-Amiloides ; Alois Alzheimer ; Oskar Fischer ; Emil Kraepelin
    Language English
    Publishing date 2023-12-01
    Publisher Thieme Revinter Publicações Ltda.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 418916-4
    ISSN 1678-4227 ; 0004-282X
    ISSN (online) 1678-4227
    ISSN 0004-282X
    DOI 10.1055/s-0043-1777722
    Database Thieme publisher's database

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ui I Zs.239: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Training of neurologists for the 21st century: cultural and professional skills

    Nitrini, Ricardo

    Arquivos de Neuro-Psiquiatria

    2022  Volume 80, Issue S 05, Page(s) 1–6

    Abstract: Background: Training of neurologists for the near future is a challenge due to the likely advances in neuroscientific methods, which will change much of our knowledge on diagnosis and treatment of neurological diseases. Objective: To comment on what may ... ...

    Abstract Background: Training of neurologists for the near future is a challenge due to the likely advances in neuroscientific methods, which will change much of our knowledge on diagnosis and treatment of neurological diseases. Objective: To comment on what may be more likely to be a constant in the very near future and to recommend how to prepare the neurologist for the 21st century. Methods: Through a critical review of recent articles on the teaching of Neurology, to present a personal view on the subject. Results: Diagnostic methods and therapeutic resources in Neurology will be greatly improved, but the central core of teaching young neurologists will continue to be the clinical/anatomical correlation. The neurologist must be prepared to be the primary physician in the care of patients with neurological disorders, although the roles of consultant and clinical neuroscientist must also be considered. In addition to technical knowledge, the neurologist must be prepared to discuss not only distressing issues related to the specialty, such as the risks of genetic diseases for family members of their patients, the inexorable progression of some diseases and the need for palliative care, but also problems not directly related to Neurology that cause anxiety and depression in the patient or that are the main reason for the initial consultation. Conclusion: neurology will be an even more important area of medicine and the neurologist must be well prepared to be the primary doctor to diagnose, treat and follow the patient with neurological disorders. In addition to technical knowledge, training in doctor-patient relations should be highlighted.
    Keywords Forecasting ; Neurologists ; Teaching ; Mentoring ; History, 21st Century ; Humanism ; Clinical-Anatomic Correlation ; Previsões ; Neurologistas ; Ensino ; Tutoria ; História, Século XXI ; Humanismo ; Correlação Anátomo-Clínica
    Language English
    Publishing date 2022-05-01
    Publisher Thieme Revinter Publicações Ltda.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 418916-4
    ISSN 1678-4227 ; 0004-282X
    ISSN (online) 1678-4227
    ISSN 0004-282X
    DOI 10.1590/0004-282X-ANP-2022-S104
    Database Thieme publisher's database

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ui I Zs.239: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Dementia in the developing world.

    Nitrini, Ricardo

    Dementia & neuropsychologia

    2017  Volume 3, Issue 1, Page(s) 1

    Language English
    Publishing date 2017-08-22
    Publishing country Brazil
    Document type Editorial
    ISSN 1980-5764
    ISSN 1980-5764
    DOI 10.1590/S1980-57642009DN30100001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Editorial: In the June 2017 issue.

    Nitrini, Ricardo

    Dementia & neuropsychologia

    2017  Volume 11, Issue 2, Page(s) 103–104

    Language English
    Publishing date 2017-08-22
    Publishing country Brazil
    Document type Editorial
    ISSN 1980-5764
    ISSN 1980-5764
    DOI 10.1590/1980-57642016dn11-020001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: In the June 2010 issue.

    Nitrini, Ricardo

    Dementia & neuropsychologia

    2017  Volume 4, Issue 2, Page(s) 85

    Language English
    Publishing date 2017-08-22
    Publishing country Brazil
    Document type Editorial
    ISSN 1980-5764
    ISSN 1980-5764
    DOI 10.1590/S1980-57642010DN40200001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: In the September 2015 issue.

    Nitrini, Ricardo

    Dementia & neuropsychologia

    2017  Volume 9, Issue 3, Page(s) 201–202

    Language English
    Publishing date 2017-08-22
    Publishing country Brazil
    Document type Editorial
    ISSN 1980-5764
    ISSN 1980-5764
    DOI 10.1590/1980-57642015DN93000001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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