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  1. Article: Anti-Ma2 Encephalitis: An Atypical Case Associated With Klüver-Bucy Syndrome and Hypothalamic Dysfunction.

    Wernz, Cort / Pupa, Lauren / Ossimetha, Ashley / Ansari, Sahifah / Moron, Fanny

    Cureus

    2023  Volume 15, Issue 6, Page(s) e40816

    Abstract: Anti-Ma2 encephalitis is a rare form of autoimmune encephalitis that has classically been described as a paraneoplastic neurobehavioral disorder due to its association with underlying malignancies. We discuss the case of a 30-year-old female with an ... ...

    Abstract Anti-Ma2 encephalitis is a rare form of autoimmune encephalitis that has classically been described as a paraneoplastic neurobehavioral disorder due to its association with underlying malignancies. We discuss the case of a 30-year-old female with an exceptionally aggressive presentation of anti-Ma2 encephalitis accompanied by Klüver-Bucy syndrome and hypothalamic dysfunction. Her course was complicated by repeated aspiration events secondary to severe hyperphagia and delays in immunosuppressive treatment due to concerns of infection. The patient's encephalitis was refractory to multiple immunosuppressive therapies and she ultimately expired before a primary malignancy could be detected and treated.
    Language English
    Publishing date 2023-06-22
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.40816
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Socioeconomic Disparities in Community Mobility Reduction and COVID-19 Growth.

    Ossimetha, Ashley / Ossimetha, Angelina / Kosar, Cyrus M / Rahman, Momotazur

    Mayo Clinic proceedings

    2020  Volume 96, Issue 1, Page(s) 78–85

    Abstract: Objective: To examine differences in community mobility reduction and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outcomes across counties with differing levels of socioeconomic disadvantage.: Methods: The sample included counties in ...

    Abstract Objective: To examine differences in community mobility reduction and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outcomes across counties with differing levels of socioeconomic disadvantage.
    Methods: The sample included counties in the United States with at least one SARS-CoV-2 case between April 1 and May 15, 2020. Outcomes were growth in SARS-CoV-2 cases, SARS-CoV-2-related deaths, and mobility reduction across three settings: retail/recreation, grocery/pharmacy, and workplace. The main explanatory variable was the social deprivation index (SDI), a composite socioeconomic disadvantage measure.
    Results: Adjusted differences in outcomes between low-, medium-, and high-SDI counties (defined by tertile) were calculated using linear regression with state-fixed effects. Workplace mobility reduction was 1.75 (95% CI, -2.36 to -1.14; P<.001) and 3.48 percentage points (95% CI, -4.21 to -2.75; P<.001) lower for medium- and high-SDI counties relative to low-SDI counties, respectively. Mobility reductions in the other settings were also significantly lower for higher-SDI counties. In analyses adjusted for SARS-CoV-2 prevalence on April 1, medium- and high-SDI counties had 1.39 (95% CI, 0.85 to 1.93; P<.001) and 2.56 (95% CI, 1.77 to 3.34; P<.001) more SARS-CoV-2 cases/1000 population on May 15 compared with low-SDI counties, respectively. Deaths per capita were also significantly higher for higher-SDI counties.
    Conclusion: Counties with higher social deprivation scores experienced greater growth in SARS-CoV-2 cases and deaths, but reduced mobility at lower rates. These findings are consistent with evidence demonstrating that economically disadvantaged communities have been disproportionately impacted by the coronavirus disease 2019 pandemic. Efforts to socially distance may be more burdensome for these communities, potentially exacerbating disparities in SARS-CoV-2-related outcomes.
    MeSH term(s) COVID-19/epidemiology ; COVID-19/mortality ; Female ; Humans ; Male ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/mortality ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Social Conditions ; Social Control, Formal ; Socioeconomic Factors ; United States/epidemiology
    Language English
    Publishing date 2020-10-22
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2020.10.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Socioeconomic Disparities in Community Mobility Reduction and COVID-19 Growth

    Ossimetha, Ashley / Ossimetha, Angelina / Kosar, Cyrus M. / Rahman, Momotazur

    Mayo Clinic Proceedings ; ISSN 0025-6196

    2020  

    Keywords General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.mayocp.2020.10.019
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Socioeconomic Disparities in Community Mobility Reduction and COVID-19 Growth

    Ossimetha, Ashley Ossimetha Angelina Kosar Cyrus M. / Rahman, Momotazur

    Mayo Clinic Proceedings

    Abstract: Objective To examine differences in community mobility reduction and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outcomes across counties with differing levels of socioeconomic disadvantage Methods The sample included US counties with at ...

    Abstract Objective To examine differences in community mobility reduction and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outcomes across counties with differing levels of socioeconomic disadvantage Methods The sample included US counties with at least one SARS-CoV-2 case during April 1 to May 15, 2020 Outcomes were growth in SARS-CoV-2 cases, SARS-CoV-2-related deaths, and mobility reduction across three settings: retail/recreation, grocery/pharmacy, and workplace The main explanatory variable was the Social Deprivation Index (SDI), a composite socioeconomic disadvantage measure Results Adjusted differences in outcomes between low-, medium-, and high-SDI counties (defined by tertile) were calculated using linear regression with state fixed effects Workplace mobility reduction was 1 75 (95% CI, -2 36 to -1 14;P< 001) and 3 48 percentage points (CI, -4 21 to -2 75;P< 001) lower for medium- and high-SDI counties relative to low-SDI counties, respectively Mobility reductions in the other settings were also significantly lower for higher-SDI counties In analyses adjusted for SARS-CoV-2 prevalence on April 1, medium- and high-SDI counties had 1 39 (CI, 0 85 to 1 93;P< 001) and 2 56 (CI, 1 77 to 3 34;P< 001) more SARS-CoV-2 cases/1,000 on May 15 compared with low-SDI counties, respectively Deaths per capita were also significantly higher for higher-SDI counties Conclusion Counties with higher social deprivation scores experienced greater growth in SARS-CoV-2 cases and deaths, but reduced mobility at lower rates These findings are consistent with evidence demonstrating that economically disadvantaged communities have been disproportionately impacted by the coronavirus 2019 pandemic Efforts to socially distance may be more burdensome for these communities, potentially exacerbating disparities in SARS-CoV-2-related outcomes
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #885380
    Database COVID19

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