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  1. Book ; Online: International strategy for tobacco control / by Allyn L. Taylor and Ruth Roemer

    Taylor, Allyn L / Roemer, Ruth / World Health Organization. Programme on Substance Abuse

    1996  

    Abstract: ONLINE ... WHO/PSA/96.6. Unpublished ... 45 p. ...

    Abstract ONLINE

    WHO/PSA/96.6. Unpublished

    45 p.
    Keywords Smoking ; Tobacco ; Public policy ; Smoking and Health ; prevention and control ; legislation
    Language English
    Publisher Geneva : World Health Organization
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Book ; Online: International strategy for tobacco control / by Allyn L. Taylor and Ruth Roemer

    Taylor, Allyn L / Roemer, Ruth / World Health Organization. Programme on Substance Abuse

    1996  

    Abstract: ONLINE ... WHO/PSA/96.6. Unpublished ... 45 p. ...

    Abstract ONLINE

    WHO/PSA/96.6. Unpublished

    45 p.
    Keywords Smoking ; Tobacco ; Public Policy ; Smoking and Health ; prevention and control ; legislation
    Language English
    Publisher World Health Organization
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  3. Article ; Online: Global Health Law: International Law and Public Health Policy

    Taylor, Allyn L.

    International Encyclopedia of Public Health

    Abstract: Abstract The field of global health law and the contribution of international organizations to its development are described. The growth and elaboration of the field of global health law in the last two decades is one of the most notable developments in ... ...

    Abstract Abstract The field of global health law and the contribution of international organizations to its development are described. The growth and elaboration of the field of global health law in the last two decades is one of the most notable developments in global health policy. In this new era of global health governance, international law has an important, albeit limited, role to play in promoting and coordinating international cooperation and national action to protect and promote global health. Particular attention is paid to the global impact of binding international agreements and other international legal instruments developed under the auspices of the World Health Organization and the World Trade Organization.
    Keywords covid19
    Publisher Elsevier; PMC
    Document type Article ; Online
    DOI 10.1016/b978-0-12-803678-5.00238-1
    Database COVID19

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  4. Article ; Online: Global Health Law: International Law and Public Health Policy

    Taylor, Allyn L.

    International Encyclopedia of Public Health

    Abstract: The field of global health law and the contribution of international organizations to its development are described. The growth and elaboration of the field of global health law in the last two decades is one of the most notable developments in global ... ...

    Abstract The field of global health law and the contribution of international organizations to its development are described. The growth and elaboration of the field of global health law in the last two decades is one of the most notable developments in global health policy. In this new era of global health governance, international law has an important, albeit limited, role to play in promoting and coordinating international cooperation and national action to protect and promote global health. Particular attention is paid to the global impact of binding international agreements and other international legal instruments developed under the auspices of the World Health Organization and the World Trade Organization.
    Keywords covid19
    Publisher Elsevier; PMC
    Document type Article ; Online
    DOI 10.1016/b978-0-12-803678-5.00238-1
    Database COVID19

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  5. Article ; Online: A matter of scholarly clarification (Comment on H. Wipfli, G. Huang, 2011. Power of the process: evaluating the impact of the framework convention on tobacco control negotiations, Health Policy, 100:107-115).

    Taylor, Allyn L

    Health policy (Amsterdam, Netherlands)

    2011  Volume 103, Issue 1, Page(s) 99; author reply 100

    MeSH term(s) Female ; Health Policy ; Humans ; Male ; Negotiating ; Smoking Prevention
    Language English
    Publishing date 2011-11
    Publishing country Ireland
    Document type Letter ; Comment
    ZDB-ID 605805-x
    ISSN 1872-6054 ; 0168-8510
    ISSN (online) 1872-6054
    ISSN 0168-8510
    DOI 10.1016/j.healthpol.2011.08.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2250: Show issues Location:
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  6. Article ; Online: Twenty-first century international lawmaking for alcohol control.

    Taylor, Allyn L / Dhillon, Ibadat S

    Addiction (Abingdon, England)

    2013  Volume 108, Issue 3, Page(s) 462

    MeSH term(s) Alcohol Drinking/prevention & control ; Humans ; International Cooperation/legislation & jurisprudence
    Language English
    Publishing date 2013-03
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 1141051-6
    ISSN 1360-0443 ; 0965-2140
    ISSN (online) 1360-0443
    ISSN 0965-2140
    DOI 10.1111/add.12063
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 551: Show issues Location:
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  7. Article ; Online: In vivo

    Williams, Dustin L / Kawaguchi, Brooke / Taylor, Nicholas B / Allyn, Gina / Badham, Marissa A / Rogers, Jeffery C / Peterson, Brittany R / Sebahar, Paul R / Haussener, Travis J / Reddy, Hariprasada Reddy Kanna / Isaacson, Brad M / Pasquina, Paul F / Looper, Ryan E

    Biofilm

    2020  Volume 2, Page(s) 100032

    Abstract: Wounds complicated by biofilms challenge even the best clinical care and can delay a return to duty for service members. A major component of treatment in wounded warriors includes infected wound management. Yet, all antibiotic therapy options have been ... ...

    Abstract Wounds complicated by biofilms challenge even the best clinical care and can delay a return to duty for service members. A major component of treatment in wounded warriors includes infected wound management. Yet, all antibiotic therapy options have been optimized against planktonic bacteria, leaving an important gap in biofilm-related wound care. We tested the efficacy of a unique compound (CZ-01179) specifically synthesized to eradicate biofilms. CZ-01179 was formulated as the active agent in a hydrogel, and tested
    Language English
    Publishing date 2020-07-17
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2590-2075
    ISSN (online) 2590-2075
    DOI 10.1016/j.bioflm.2020.100032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Addressing the global tragedy of needless pain: rethinking the United Nations single convention on narcotic drugs.

    Taylor, Allyn L

    The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics

    2007  Volume 35, Issue 4, Page(s) 556–70, 511

    Abstract: The lack of medical availability of effective pain medication is an enduring and expanding global health calamity. Despite important medical advances, pain remains severely under-treated worldwide, particularly in developing countries. This article ... ...

    Abstract The lack of medical availability of effective pain medication is an enduring and expanding global health calamity. Despite important medical advances, pain remains severely under-treated worldwide, particularly in developing countries. This article contributes to the discussion of this global health crisis by considering international legal and institutional mechanisms to promote wider accessibility to critical narcotic drugs for pain relief.
    MeSH term(s) Chronic Disease ; Drug and Narcotic Control/legislation & jurisprudence ; Global Health ; Humans ; International Cooperation/legislation & jurisprudence ; Narcotics/economics ; Narcotics/supply & distribution ; Narcotics/therapeutic use ; Pain/drug therapy ; Pain/epidemiology ; United Nations/legislation & jurisprudence
    Chemical Substances Narcotics
    Language English
    Publishing date 2007
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1168812-9
    ISSN 1748-720X ; 1073-1105 ; 0277-8459
    ISSN (online) 1748-720X
    ISSN 1073-1105 ; 0277-8459
    DOI 10.1111/j.1748-720X.2007.00180.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2075: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: An international legal strategy for alcohol control: not a framework convention--at least not yet.

    Taylor, Allyn L / Dhillon, Ibadat S

    Addiction (Abingdon, England)

    2013  Volume 108, Issue 3, Page(s) 450–455

    Abstract: Aims: The perceived success of the Framework Convention on Tobacco Control (FCTC) in influencing national and global public health policies has led to growing interest in promulgating new international legal instruments to address global health issues- ... ...

    Abstract Aims: The perceived success of the Framework Convention on Tobacco Control (FCTC) in influencing national and global public health policies has led to growing interest in promulgating new international legal instruments to address global health issues-including calls for a Framework Convention on Alcohol Control (FCAC).
    Methods: Despite broad support in the public health community, the authors caution that an analysis of the value of lawmaking for alcohol control cannot rest solely on the character of the underlying public health challenge and the similarities between alcohol control and tobacco control. Other factors must be considered, including the relative political feasibility for global health lawmaking. The potential contribution of non-binding international legal instruments to advancing global alcohol control, in particular, deserves strong consideration.
    Results: The authors propose a gradual international legal strategy for alcohol control, starting with a non-binding code of practice focusing on areas of critical concern with wide political consensus, leading over time to a comprehensive binding treaty. Although often dismissed as ineffective relative to treaties, non-binding international legal instruments have particular strengths and can create both norms and processes that impact the behavior of states and other actors, overcoming a number of limitations of more rigid legally binding strategies.
    Conclusions: Ultimately, the authors contend that the negotiation and adoption of a non-binding international legal instrument as a first step in a long-run legal strategy offers a more politically realistic, and potentially superior, alternative to immediate efforts to achieve a Framework Convention on Alcohol Control.
    MeSH term(s) Alcohol Drinking/legislation & jurisprudence ; Alcohol Drinking/prevention & control ; Codes of Ethics ; Global Health ; Humans ; International Cooperation/legislation & jurisprudence ; World Health Organization
    Language English
    Publishing date 2013-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 1141051-6
    ISSN 1360-0443 ; 0965-2140
    ISSN (online) 1360-0443
    ISSN 0965-2140
    DOI 10.1111/j.1360-0443.2012.03919.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 551: Show issues Location:
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  10. Article ; Online: G protein-coupled receptor kinase 3 modulates mesenchymal stem cell proliferation and differentiation through sphingosine-1-phosphate receptor regulation.

    Brozowski, Jaime M / Timoshchenko, Roman G / Serafin, D Stephen / Allyn, Brittney / Koontz, Jessica / Rabjohns, Emily M / Rampersad, Rishi R / Ren, Yinshi / Eudy, Amanda M / Harris, Taylor F / Abraham, David / Mattox, Daniel / Rubin, Clinton T / Hilton, Matthew J / Rubin, Janet / Allbritton, Nancy L / Billard, Matthew J / Tarrant, Teresa K

    Stem cell research & therapy

    2022  Volume 13, Issue 1, Page(s) 37

    Abstract: Background: The bone marrow niche supports hematopoietic cell development through intimate contact with multipotent stromal mesenchymal stem cells; however, the intracellular signaling, function, and regulation of such supportive niche cells are still ... ...

    Abstract Background: The bone marrow niche supports hematopoietic cell development through intimate contact with multipotent stromal mesenchymal stem cells; however, the intracellular signaling, function, and regulation of such supportive niche cells are still being defined. Our study was designed to understand how G protein receptor kinase 3 (GRK3) affects bone marrow mesenchymal stem cell function by examining primary cells from GRK3-deficient mice, which we have previously published to have a hypercellular bone marrow and leukocytosis through negative regulation of CXCL12/CXCR4 signaling.
    Methods: Murine GRK3-deficient bone marrow mesenchymal stromal cells were harvested and cultured to differentiate into three lineages (adipocyte, chondrocyte, and osteoblast) to confirm multipotency and compared to wild type cells. Immunoblotting, modified-TANGO experiments, and flow cytometry were used to further examine the effects of GRK3 deficiency on bone marrow mesenchymal stromal cell receptor signaling. Microcomputed tomography was used to determine trabecular and cortical bone composition of GRK3-deficient mice and standard ELISA to quantitate CXCL12 production from cellular cultures.
    Results: GRK3-deficient, bone marrow-derived mesenchymal stem cells exhibit enhanced and earlier osteogenic differentiation in vitro. The addition of a sphingosine kinase inhibitor abrogated the osteogenic proliferation and differentiation, suggesting that sphingosine-1-phosphate receptor signaling was a putative G protein-coupled receptor regulated by GRK3. Immunoblotting showed prolonged ERK1/2 signaling after stimulation with sphingosine-1-phosphate in GRK3-deficient cells, and modified-TANGO assays suggested the involvement of β-arrestin-2 in sphingosine-1-phosphate receptor internalization.
    Conclusions: Our work suggests that GRK3 regulates sphingosine-1-phosphate receptor signaling on bone marrow mesenchymal stem cells by recruiting β-arrestin to the occupied GPCR to promote internalization, and lack of such regulation affects mesenchymal stem cell functionality.
    MeSH term(s) Animals ; Cell Differentiation ; Cell Proliferation ; Mesenchymal Stem Cells/metabolism ; Mice ; Osteogenesis ; Sphingosine-1-Phosphate Receptors ; X-Ray Microtomography
    Chemical Substances Sphingosine-1-Phosphate Receptors
    Language English
    Publishing date 2022-01-29
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2548671-8
    ISSN 1757-6512 ; 1757-6512
    ISSN (online) 1757-6512
    ISSN 1757-6512
    DOI 10.1186/s13287-022-02715-4
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