Article ; Online: Anal Cancer and Anal Cancer Screening.
Clinical obstetrics and gynecology
2023 Volume 66, Issue 3, Page(s) 516–533
Abstract: This chapter provides an overview of anal cancer and contemporary approaches for anal precancer detection, beginning with a discussion of the biology and natural history of anal squamous cell carcinoma, the predominant human papillomavirus -associated ... ...
Abstract | This chapter provides an overview of anal cancer and contemporary approaches for anal precancer detection, beginning with a discussion of the biology and natural history of anal squamous cell carcinoma, the predominant human papillomavirus -associated histologic subtype of anal cancer. This section is followed by a description of the epidemiology of anal cancer, including trends in incidence and mortality, a discussion of populations with elevated risk for anal cancer and an overview of associated risk factors. The remainder of the chapter provides the most up-to-date evidence on tools and approaches for anal cancer prevention, screening, and early detection; including, the role of human papillomavirus vaccination for primary prevention; anal cytology, high resolution anoscopy and novel biomarkers for secondary prevention; and digital anal-rectal examination for early detection. |
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MeSH term(s) | Humans ; Papillomavirus Infections/complications ; Papillomavirus Infections/diagnosis ; Papillomavirus Infections/prevention & control ; Early Detection of Cancer ; Papillomavirus Vaccines/therapeutic use ; Anal Canal/pathology ; Anus Neoplasms/diagnosis ; Anus Neoplasms/epidemiology ; Anus Neoplasms/prevention & control ; Papillomaviridae |
Chemical Substances | Papillomavirus Vaccines |
Language | English |
Publishing date | 2023-07-13 |
Publishing country | United States |
Document type | Journal Article |
ZDB-ID | 391207-3 |
ISSN | 1532-5520 ; 0009-9201 |
ISSN (online) | 1532-5520 |
ISSN | 0009-9201 |
DOI | 10.1097/GRF.0000000000000789 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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