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  1. Article ; Online: Mitigating the Impact of Socioeconomic Status on Listing for Lung Transplantation in Cystic Fibrosis.

    Hadjiliadis, Denis

    Annals of the American Thoracic Society

    2020  Volume 17, Issue 11, Page(s) 1374–1375

    MeSH term(s) Cohort Studies ; Cystic Fibrosis/surgery ; Humans ; Lung Transplantation ; Social Class ; Waiting Lists
    Language English
    Publishing date 2020-10-30
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202007-905ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A new era has dawned for persons with cystic fibrosis; however many knowledge gaps exist in our efforts to improve care.

    Hadjiliadis, Denis / Clausen, Emily Siu

    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

    2022  Volume 21, Issue 3, Page(s) 383–384

    MeSH term(s) Aminophenols ; Cystic Fibrosis/epidemiology ; Cystic Fibrosis/therapy ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Humans ; Mutation
    Chemical Substances Aminophenols ; Cystic Fibrosis Transmembrane Conductance Regulator (126880-72-6)
    Language English
    Publishing date 2022-04-16
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2084724-5
    ISSN 1873-5010 ; 1569-1993
    ISSN (online) 1873-5010
    ISSN 1569-1993
    DOI 10.1016/j.jcf.2022.04.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Age at Lung Transplant Impacts Post-Transplant Survival in Cystic Fibrosis; Why?

    Clausen, Emily S / Hadjiliadis, Denis

    Annals of the American Thoracic Society

    2020  Volume 18, Issue 1, Page(s) 28–29

    MeSH term(s) Adult ; Cystic Fibrosis/surgery ; Graft Survival ; Humans ; Lung Transplantation
    Language English
    Publishing date 2020-12-25
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202009-1190ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Early-phase insulin secretion during mixed-meal tolerance testing predicts β-cell function and secretory capacity in cystic fibrosis.

    Sheikh, Saba / Stefanovski, Darko / Kilberg, Marissa J / Hadjiliadis, Denis / Rubenstein, Ronald C / Rickels, Michael R / Kelly, Andrea

    Frontiers in endocrinology

    2024  Volume 15, Page(s) 1340346

    Abstract: Insulin secretion within 30 minutes of nutrient ingestion is reduced in people with cystic fibrosis (PwCF) and pancreatic insufficiency and declines with worsening glucose tolerance. The glucose potentiated arginine (GPA) test is validated for ... ...

    Abstract Insulin secretion within 30 minutes of nutrient ingestion is reduced in people with cystic fibrosis (PwCF) and pancreatic insufficiency and declines with worsening glucose tolerance. The glucose potentiated arginine (GPA) test is validated for quantifying β-cell secretory capacity as an estimate of functional β-cell mass but requires technical expertise and is burdensome. This study sought to compare insulin secretion during mixed-meal tolerance testing (MMTT) to GPA-derived parameters in PwCF.
    Methods: Secondary data analysis of CF-focused prospective studies was performed in PwCF categorized as 1) pancreatic insufficient [PI-CF] or 2) pancreatic sufficient [PS-CF] and in 3) non-CF controls. MMTT: insulin secretory rates (ISR) were derived by parametric deconvolution using 2-compartment model of C-peptide kinetics, and incremental area under the curve (AUC) was calculated for 30, 60 and 180-minutes. GPA: acute insulin (AIR) and C-peptide responses (ACR) were calculated as average post-arginine insulin or C-peptide response minus pre-arginine insulin or C-peptide under fasting (AIR
    Results: 85 PwCF (45 female; 75 PI-CF and 10 PS-CF) median (range) age 23 (6-56) years with BMI 23 (13-34) kg/m
    Conclusion: Early-phase insulin secretion during MMTT can accurately predict GPA-derived measures of β-cell function and secretory capacity when functional β-cell mass is reduced. These data can inform future multicenter studies requiring reliable, standardized, and technically feasible testing mechanisms to quantify β-cell function and secretory capacity.
    MeSH term(s) Female ; Humans ; Young Adult ; Adult ; Insulin Secretion ; Cystic Fibrosis ; C-Peptide ; Prospective Studies ; Insulin ; Arginine ; Glucose
    Chemical Substances C-Peptide ; Insulin ; Arginine (94ZLA3W45F) ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2024-02-20
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2024.1340346
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: ACP Journal Club. Ivacaftor improved lung function in cystic fibrosis with G551D mutation.

    Hadjiliadis, Denis

    Annals of internal medicine

    2012  Volume 156, Issue 8, Page(s) JC4–10

    Language English
    Publishing date 2012-04-17
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/0003-4819-156-8-201204170-02010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Electronic health nudges to improve reproductive health care for women with cystic fibrosis.

    Roe, Andrea H / Yapalater, Sophia / Hadjiliadis, Denis

    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

    2020  Volume 20, Issue 3, Page(s) 397–398

    MeSH term(s) Adult ; Cystic Fibrosis/complications ; Electronic Health Records ; Female ; Health Services Needs and Demand ; Humans ; Quality Improvement ; Reproductive Health
    Language English
    Publishing date 2020-11-12
    Publishing country Netherlands
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2084724-5
    ISSN 1873-5010 ; 1569-1993
    ISSN (online) 1873-5010
    ISSN 1569-1993
    DOI 10.1016/j.jcf.2020.11.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The 49th parallel: Does geographic position affect longevity of patients with cystic fibrosis?

    Hadjiliadis, Denis / Valapour, Maryam / Chaparro, Cecilia / Cypel, Marcelo / Cooper, Joel D

    The Journal of thoracic and cardiovascular surgery

    2022  Volume 165, Issue 4, Page(s) 1604–1607

    MeSH term(s) Humans ; United States ; Cystic Fibrosis ; Lung Transplantation ; Tissue and Organ Procurement ; Waiting Lists ; Tissue Donors
    Language English
    Publishing date 2022-03-01
    Publishing country United States
    Document type Editorial
    ZDB-ID 3104-5
    ISSN 1097-685X ; 0022-5223
    ISSN (online) 1097-685X
    ISSN 0022-5223
    DOI 10.1016/j.jtcvs.2022.01.048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Cervical mucus quality in females with and without cystic fibrosis.

    Roe, Andrea H / Koelper, Nathanael / McAllister, Arden / Barnhart, Kurt T / Schreiber, Courtney A / Hadjiliadis, Denis

    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

    2023  Volume 22, Issue 5, Page(s) 804–805

    MeSH term(s) Female ; Humans ; Cystic Fibrosis/complications ; Cervix Mucus ; Mucociliary Clearance ; Mucus
    Language English
    Publishing date 2023-03-23
    Publishing country Netherlands
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2084724-5
    ISSN 1873-5010 ; 1569-1993
    ISSN (online) 1873-5010
    ISSN 1569-1993
    DOI 10.1016/j.jcf.2023.03.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Should weight be a criterion for lung transplant selection?

    Hadjiliadis, Denis

    Expert review of respiratory medicine

    2010  Volume 4, Issue 1, Page(s) 1–3

    MeSH term(s) Body Weight ; Humans ; Lung Transplantation/mortality ; Obesity/complications ; Patient Selection ; Practice Guidelines as Topic ; Risk Factors
    Language English
    Publishing date 2010-04-08
    Publishing country England
    Document type Editorial
    ZDB-ID 2479146-5
    ISSN 1747-6356 ; 1747-6348
    ISSN (online) 1747-6356
    ISSN 1747-6348
    DOI 10.1586/ers.09.62
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Cystic fibrosis: not just an exocrinopathy anymore?

    Hadjiliadis, Denis

    Southern medical journal

    2008  Volume 101, Issue 6, Page(s) 585

    MeSH term(s) Colonic Neoplasms/complications ; Comorbidity ; Complement Pathway, Alternative/immunology ; Cystic Fibrosis/complications ; Cystic Fibrosis/immunology ; Cystic Fibrosis/surgery ; Glomerulonephritis, Membranoproliferative/etiology ; Glomerulonephritis, Membranoproliferative/immunology ; Humans ; Immunity, Innate/immunology ; Lung Transplantation/immunology ; Risk Factors
    Language English
    Publishing date 2008-06
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 185329-6
    ISSN 1541-8243 ; 0038-4348
    ISSN (online) 1541-8243
    ISSN 0038-4348
    DOI 10.1097/SMJ.0b013e318172f6b2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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