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  1. Article: Network pharmacology and experiment validation investigate the potential mechanism of triptolide in oral squamous cell carcinoma.

    Hao, Puyu / Zhang, Pengcheng / Liu, Ying / Cao, Yang / Du, Lianqun / Gao, Li / Dong, Qingyang

    Frontiers in pharmacology

    2024  Volume 14, Page(s) 1302059

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2024-01-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1302059
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Article ; Online: Corporate taxes and labor market informality evidence from China

    Deng, Guoying / Du, Pengcheng / Hernandez, Manuel A. / and Xu, Shu

    2024  

    Abstract: Development Strategies and Governance (DSG) ...

    Abstract Development Strategies and Governance (DSG)
    Keywords taxes
    Language English
    Publishing country us
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Genomic Epidemiology of

    Fan, Shuaihua / Duan, Ning / Chen, Wenjing / Zhao, Xiuying / Wang, Lijun / Du, Pengcheng / Guo, Jun

    Pathogens (Basel, Switzerland)

    2023  Volume 12, Issue 2

    Abstract: Streptococcus ... ...

    Abstract Streptococcus pneumoniae
    Language English
    Publishing date 2023-02-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens12020284
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  4. Article ; Online: Genomic characterisation of bla

    Pan, Fen / Xu, Qi / Jiang, Cong / Du, Qingqing / Yu, Fangyuan / Chen, Pengcheng / Zhang, Hong

    Journal of global antimicrobial resistance

    2024  Volume 37, Page(s) 81–85

    Abstract: Objectives: The dissemination of New Delhi metallo-β-lactamase-5 (NDM-5) among various species of Enterobacterales has attracted serious global attention. Here, we characterise the genomic characterisation of bla: Methods: Antimicrobial ... ...

    Abstract Objectives: The dissemination of New Delhi metallo-β-lactamase-5 (NDM-5) among various species of Enterobacterales has attracted serious global attention. Here, we characterise the genomic characterisation of bla
    Methods: Antimicrobial susceptibility and multilocus sequence typing was performed for the KA3. The plasmid conjugation assay and plasmid stability of the KA3 (pNDM-KA3) were also analysed. The pNDM-KA3 plasmid was further analysed by whole-genome sequencing and comparative analysis to determine the genetic environment of bla
    Results: The KA3 strain belongs to ST4 and shows high resistance to β-lactam antibiotics, including carbapenems, but is susceptible to ciprofloxacin, amikacin, tigecycline, and colistin. The pNDM-KA3 was successfully transferred to the recipient E. coli J53 and showed strong stability in K. aerogenes. Genomic sequencing revealed that the pNDM-KA3 plasmid was assigned to plasmid incompatibility group X3 with 43367 bp, and a conserved structure sequence of △IS3000-△ISAba125-IS5-bla
    Conclusions: Continued monitoring for the dissemination of bla
    Language English
    Publishing date 2024-03-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2710046-7
    ISSN 2213-7173 ; 2213-7173
    ISSN (online) 2213-7173
    ISSN 2213-7173
    DOI 10.1016/j.jgar.2024.02.011
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  5. Article ; Online: FSformer: A combined frequency separation network and transformer for LDCT denoising.

    Kang, Jiaqi / Liu, Yi / Zhang, Pengcheng / Guo, Niu / Wang, Lei / Du, Yinglin / Gui, Zhiguo

    Computers in biology and medicine

    2024  Volume 173, Page(s) 108378

    Abstract: Low-dose computed tomography (LDCT) has been widely concerned in the field of medical imaging because of its low radiation hazard to humans. However, under low-dose radiation scenarios, a large amount of noise/artifacts are present in the reconstructed ... ...

    Abstract Low-dose computed tomography (LDCT) has been widely concerned in the field of medical imaging because of its low radiation hazard to humans. However, under low-dose radiation scenarios, a large amount of noise/artifacts are present in the reconstructed image, which reduces the clarity of the image and is not conducive to diagnosis. To improve the LDCT image quality, we proposed a combined frequency separation network and Transformer (FSformer) for LDCT denoising. Firstly, FSformer decomposes the LDCT images into low-frequency images and multi-layer high-frequency images by frequency separation blocks. Then, the low-frequency components are fused with the high-frequency components of different layers to remove the noise in the high-frequency components with the help of the potential texture of low-frequency parts. Next, the estimated noise images can be obtained by using Transformer stage in the frequency aggregation denoising block. Finally, they are fed into the reconstruction prediction block to obtain improved quality images. In addition, a compound loss function with frequency loss and Charbonnier loss is used to guide the training of the network. The performance of FSformer has been validated and evaluated on AAPM Mayo dataset, real Piglet dataset and clinical dataset. Compared with previous representative models in different architectures, FSformer achieves the optimal metrics with PSNR of 33.7714 dB and SSIM of 0.9254 on Mayo dataset, the testing time is 1.825 s. The experimental results show that FSformer is a state-of-the-art (SOTA) model with noise/artifact suppression and texture/organization preservation. Moreover, the model has certain robustness and can effectively improve LDCT image quality.
    MeSH term(s) Animals ; Humans ; Swine ; Signal-To-Noise Ratio ; Tomography, X-Ray Computed/methods ; Image Processing, Computer-Assisted/methods ; Algorithms
    Language English
    Publishing date 2024-03-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 127557-4
    ISSN 1879-0534 ; 0010-4825
    ISSN (online) 1879-0534
    ISSN 0010-4825
    DOI 10.1016/j.compbiomed.2024.108378
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 653: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: The impact of poaching and regime switching on the dynamics of single-species model.

    Du, Pengcheng / Liao, Yunhua

    Journal of biological dynamics

    2021  Volume 15, Issue 1, Page(s) 250–268

    Abstract: It is widely recognized that the criminal act of poaching has brought tremendous damage to biodiversity. This paper employs a stochastic single-species model with regime switching to investigate the impact of poaching. We first carry out the survival ... ...

    Abstract It is widely recognized that the criminal act of poaching has brought tremendous damage to biodiversity. This paper employs a stochastic single-species model with regime switching to investigate the impact of poaching. We first carry out the survival analysis and obtain sufficient conditions for the extinction and persistence in mean of the single-species population. Then, we show that the model is positive recurrent by constructing suitable Lyapunov function. Finally, numerical simulations are carried out to support our theoretical results. It is found that: (i) As the intensity of poaching increases, the odds of being at risk of extinction increases for the single-species population. (ii) The regime switching can suppress the extinction of the single-species population. (iii) The white noise is detrimental to the survival of the single-species population. (iv) Increasing the criminal cost of poaching and establishing animal sanctuaries are important ways to protect biodiversity.
    MeSH term(s) Animals ; Models, Biological ; Stochastic Processes
    Language English
    Publishing date 2021-04-15
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2274786-2
    ISSN 1751-3766 ; 1751-3758
    ISSN (online) 1751-3766
    ISSN 1751-3758
    DOI 10.1080/17513758.2021.1914757
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  7. Article ; Online: Dissemination of the mobilised RND efflux pump gene cluster tmexCD-toprJ among Klebsiella pneumoniae.

    Liu, Chao / Guo, Jun / Lu, Ming / Shen, Ning / Du, Pengcheng

    The Lancet. Microbe

    2022  Volume 4, Issue 3, Page(s) e135

    MeSH term(s) Klebsiella pneumoniae/genetics ; Anti-Bacterial Agents ; Bacterial Proteins/genetics ; Multigene Family
    Chemical Substances Anti-Bacterial Agents ; Bacterial Proteins
    Language English
    Publishing date 2022-11-24
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ISSN 2666-5247
    ISSN (online) 2666-5247
    DOI 10.1016/S2666-5247(22)00325-1
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  8. Article: Role of exhaled hydrogen sulfide in the diagnosis of colorectal cancer.

    Du, Peizhun / Tseng, Yujen / Liu, Pengcheng / Zhang, Huilu / Huang, Guangjian / Hu, Cheng'en / Chen, Jian

    BMJ open gastroenterology

    2024  Volume 11, Issue 1

    Abstract: Background: Colorectal cancer (CRC) is often accompanied by increased excretion of hydrogen sulfide (H: Methods: A total of 80 people with normal colonoscopy results and 57 patients with CRC were enrolled into the present observational cohort study. ... ...

    Abstract Background: Colorectal cancer (CRC) is often accompanied by increased excretion of hydrogen sulfide (H
    Methods: A total of 80 people with normal colonoscopy results and 57 patients with CRC were enrolled into the present observational cohort study. Exhaled oral and nasal H
    Results: The amount of exhaled H
    Conclusion: Exhaled H
    MeSH term(s) Humans ; Hydrogen Sulfide/analysis ; Neoplasm Staging ; ROC Curve ; Colorectal Neoplasms/diagnosis ; Colorectal Neoplasms/pathology
    Chemical Substances Hydrogen Sulfide (YY9FVM7NSN)
    Language English
    Publishing date 2024-02-20
    Publishing country England
    Document type Observational Study ; Journal Article
    ISSN 2054-4774
    ISSN 2054-4774
    DOI 10.1136/bmjgast-2023-001229
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  9. Article ; Online: Emergence and Inter- and Intrahost Evolution of Pandrug-Resistant Klebsiella pneumoniae Coharboring

    Liu, Chao / Du, Pengcheng / Yang, Ping / Zheng, Jiajia / Yi, Juan / Lu, Ming / Shen, Ning

    Microbiology spectrum

    2023  , Page(s) e0278622

    Abstract: Klebsiella pneumoniae is capable of acquiring various exogenous genetic elements and subsequently conferring high antimicrobial resistance. Recently, a plasmid-mediated RND family multidrug efflux pump gene cluster, ...

    Abstract Klebsiella pneumoniae is capable of acquiring various exogenous genetic elements and subsequently conferring high antimicrobial resistance. Recently, a plasmid-mediated RND family multidrug efflux pump gene cluster,
    Language English
    Publishing date 2023-01-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.02786-22
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  10. Article ; Online: Prevalence of elder abuse and victim-related risk factors during the COVID-19 pandemic in China

    Pengcheng Du / Yu Chen

    BMC Public Health, Vol 21, Iss 1, Pp 1-

    2021  Volume 10

    Abstract: Abstract Background With the accelerated aging of the Chinese population, elder abuse has become a serious social problem. As COVID-19 has had a very large impact on economic development and lifestyle in China, it has also affected elder abuse. The ... ...

    Abstract Abstract Background With the accelerated aging of the Chinese population, elder abuse has become a serious social problem. As COVID-19 has had a very large impact on economic development and lifestyle in China, it has also affected elder abuse. The purpose of this study is to estimate the prevalence of elder abuse in China during the COVID-19 pandemic, and to identify changes in risk factors for elder abuse in the context of COVID-19. Methods We designed a cross-sectional study. In Hunan Province, a face-to-face questionnaire survey was conducted among elderly people over 65 years of age. To ensure the consistency of the measurement standards, we used the elder abuse questionnaire from the “Third Survey on Chinese Women’s Social Status.” According to related research, we selected 10 victim-related risk factors as independent variables. A logistic regression model was established to analyze the relationship between the independent variables and the four kinds of abuse. Results We collected 10,362 samples from Hunan Province. During the COVID-19 pandemic, the prevalence of financial abuse and neglect was significantly higher than that in 2010. Income had a significant impact on the four types of abuse. The lower the income was, the greater the risk of abuse. Moreover, factors such as an older age, being a woman, a lower cognitive ability, and not having a cohabiting spouse increased the possibility of abuse. The greater the number of children was, the greater the risks of physical abuse, financial abuse, and elder neglect. Seniors with higher education levels, those who frequently participated in social activities, and those with religious beliefs were less likely to suffer abuse. Conclusions During the COVID-19 epidemic, the prevalence of elder abuse in China has increased, which may be related to economic instability and social distancing measures. Increasing the income of the elderly and giving them more social support are important measures to reduce the prevalence of elder abuse.
    Keywords COVID-19 ; Elder abuse ; Risk factor ; China ; Public aspects of medicine ; RA1-1270
    Subject code 360
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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