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  1. Article ; Online: Introduction to special focus section on prostate cancer imaging.

    Froemming, Adam T / Silva, Alvin C

    Abdominal radiology (New York)

    2016  Volume 41, Issue 5, Page(s) 797

    Language English
    Publishing date 2016
    Publishing country United States
    Document type Editorial
    ZDB-ID 2839786-1
    ISSN 2366-0058 ; 2366-004X
    ISSN (online) 2366-0058
    ISSN 2366-004X
    DOI 10.1007/s00261-016-0759-y
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1262: Show issues Location:
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  2. Article ; Online: Special section introduction: elastography.

    Silva, Alvin C / Beland, Michael D

    Abdominal imaging

    2015  Volume 40, Issue 4, Page(s) 679

    MeSH term(s) Elasticity Imaging Techniques ; Humans ; Magnetic Resonance Imaging
    Language English
    Publishing date 2015-04
    Publishing country United States
    Document type Letter
    ZDB-ID 1144553-1
    ISSN 1432-0509 ; 0942-8925
    ISSN (online) 1432-0509
    ISSN 0942-8925
    DOI 10.1007/s00261-015-0405-0
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    Zs.A 1262: Show issues Location:
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  3. Article: Performing Automatic Identification and Staging of Urothelial Carcinoma in Bladder Cancer Patients Using a Hybrid Deep-Machine Learning Approach.

    Sarkar, Suryadipto / Min, Kong / Ikram, Waleed / Tatton, Ryan W / Riaz, Irbaz B / Silva, Alvin C / Bryce, Alan H / Moore, Cassandra / Ho, Thai H / Sonpavde, Guru / Abdul-Muhsin, Haidar M / Singh, Parminder / Wu, Teresa

    Cancers

    2023  Volume 15, Issue 6

    Abstract: Accurate clinical staging of bladder cancer aids in optimizing the process of clinical decision-making, thereby tailoring the effective treatment and management of patients. While several radiomics approaches have been developed to facilitate the process ...

    Abstract Accurate clinical staging of bladder cancer aids in optimizing the process of clinical decision-making, thereby tailoring the effective treatment and management of patients. While several radiomics approaches have been developed to facilitate the process of clinical diagnosis and staging of bladder cancer using grayscale computed tomography (CT) scans, the performances of these models have been low, with little validation and no clear consensus on specific imaging signatures. We propose a hybrid framework comprising pre-trained deep neural networks for feature extraction, in combination with statistical machine learning techniques for classification, which is capable of performing the following classification tasks: (1) bladder cancer tissue vs. normal tissue, (2) muscle-invasive bladder cancer (MIBC) vs. non-muscle-invasive bladder cancer (NMIBC), and (3) post-treatment changes (PTC) vs. MIBC.
    Language English
    Publishing date 2023-03-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15061673
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  4. Article: Long-term outcomes of prostate intensity-modulated radiation therapy incorporating a simultaneous intra-prostatic MRI-directed boost.

    Laughlin, Brady S / Silva, Alvin C / Vora, Sujay A / Keole, Sameer R / Wong, William W / Schild, Michael H / Schild, Steven E

    Frontiers in oncology

    2022  Volume 12, Page(s) 921465

    Abstract: Purpose/objectives: This retrospective study demonstrates the long-term outcomes of treating prostate cancer using intensity modulated (IMRT) with incorporation of MRI-directed boost.: Materials/methods: From February 2009 to February 2013, 78 men ... ...

    Abstract Purpose/objectives: This retrospective study demonstrates the long-term outcomes of treating prostate cancer using intensity modulated (IMRT) with incorporation of MRI-directed boost.
    Materials/methods: From February 2009 to February 2013, 78 men received image-guided IMRT delivering 77.4 Gy in 44 fractions with simultaneously integrated boost to 81-83 Gy to an MRI-identified lesion. Patients with intermediate-risk or high-risk prostate cancer were recommended to receive 6 and 24-36 months of adjuvant hormonal therapy, respectively.
    Results: Median follow-up was 113 months (11-147). There were 18 low-risk, 43 intermediate-risk, and 17 high-risk patients per NCCN risk stratification included in this study. Adjuvant hormonal therapy was utilized in 32 patients (41%). The 10-year biochemical control rate for all patients was 77%. The 10-year biochemical control rates for low-risk, intermediate-risk, and high-risk diseases were 94%, 81%, and 88%, respectively (p = 0.35). The 10-year rates of local control, distant control, and survival were 99%, 88%, and 66%, respectively. Of 25 patients who died, only four (5%) died of prostate cancer. On univariate analysis, T-category and pretreatment PSA level were associated with distant failure rate (p = 0.02). There was no grade =3 genitourinary and gastrointestinal toxicities that persisted at the last follow-up.
    Conclusions: This study demonstrated the long-term efficacy of using MRI to define an intra-prostatic lesion for SIB to 81-83Gy while treating the entire prostate gland to 77.4 Gy with IMRT. Our study confirms that modern MRI can be used to locally intensify dose to prostate tumors providing high long-term disease control while maintaining favorable long-term toxicity.
    Language English
    Publishing date 2022-08-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2022.921465
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  5. Article ; Online: Pearls and pitfalls of response evaluation criteria in solid tumors (RECIST) v1.1 non-target lesion assessment.

    Morse, Brian / Jeong, Daniel / Ihnat, Gary / Silva, Alvin C

    Abdominal radiology (New York)

    2018  Volume 44, Issue 2, Page(s) 766–774

    Abstract: Oncologic imaging is an important facet of abdominal imaging that radiologists encounter nearly every day. Many oncology clinical trials utilize response evaluation criteria in solid tumors (RECIST) version 1.1 which divides tumor sites into target and ... ...

    Abstract Oncologic imaging is an important facet of abdominal imaging that radiologists encounter nearly every day. Many oncology clinical trials utilize response evaluation criteria in solid tumors (RECIST) version 1.1 which divides tumor sites into target and non-target lesions. Although RECIST v1.1 provides clear instructions regarding the use of imaging in clinical trials, errors in response assessment still occur using these criteria. This is especially true of response assessment with regards to non-target lesions which involve rules which are less well-defined and somewhat subjective. This pictorial essay will review RECIST v1.1 guidelines and common non-target lesion errors which can occur at baseline and follow-up response assessment.
    MeSH term(s) Diagnostic Imaging/methods ; Humans ; Neoplasms/diagnostic imaging ; Response Evaluation Criteria in Solid Tumors ; Treatment Outcome
    Language English
    Publishing date 2018-10-29
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2839786-1
    ISSN 2366-0058 ; 2366-004X
    ISSN (online) 2366-0058
    ISSN 2366-004X
    DOI 10.1007/s00261-018-1752-4
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  6. Article: Bladder Endometriosis: Ultrasound and MRI Findings.

    Beaty, Sean D / Silva, Alvin C / De Petris, Giovanni

    Radiology case reports

    2015  Volume 1, Issue 3, Page(s) 92–95

    Abstract: Bladder endometriosis is a rare cause of a localized bladder mass, potentially mimicking a neoplasm at cross-sectional imaging. We present the case of a patient with cyclic pelvic pain and urinary symptoms secondary to bladder endometriosis, with ... ...

    Abstract Bladder endometriosis is a rare cause of a localized bladder mass, potentially mimicking a neoplasm at cross-sectional imaging. We present the case of a patient with cyclic pelvic pain and urinary symptoms secondary to bladder endometriosis, with characteristic pelvic ultrasound and magnetic resonance imaging findings. Potential pathological mechanisms are discussed.
    Language English
    Publishing date 2015-11-06
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.2484/rcr.v1i3.16
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  7. Article ; Online: AJR teaching file: Necrotic mass invading the heart.

    Silva, Alvin C

    AJR. American journal of roentgenology

    2006  Volume 187, Issue 3 Suppl, Page(s) S473–5

    MeSH term(s) Adult ; Female ; Heart Neoplasms/diagnosis ; Heart Neoplasms/secondary ; Humans ; Leiomyosarcoma/diagnosis ; Leiomyosarcoma/secondary ; Magnetic Resonance Imaging ; Myocardium/pathology ; Necrosis ; Neoplasm Invasiveness ; Tomography, X-Ray Computed ; Uterine Neoplasms/pathology
    Language English
    Publishing date 2006-09
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 82076-3
    ISSN 1546-3141 ; 0361-803X ; 0092-5381
    ISSN (online) 1546-3141
    ISSN 0361-803X ; 0092-5381
    DOI 10.2214/AJR.05.0970
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  8. Article ; Online: AJR Teaching File: enlarging splenic mass after nephrectomy.

    Silva, Alvin C

    AJR. American journal of roentgenology

    2006  Volume 186, Issue 6 Suppl 1, Page(s) S449–51

    MeSH term(s) Aged ; Diagnosis, Differential ; Granuloma, Plasma Cell/diagnosis ; Hamartoma/diagnosis ; Hemangioma/diagnosis ; Humans ; Kidney Neoplasms/pathology ; Magnetic Resonance Imaging ; Male ; Nephrectomy/adverse effects ; Splenic Diseases/diagnosis ; Splenic Neoplasms/diagnosis ; Splenic Neoplasms/secondary
    Language English
    Publishing date 2006-06
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 82076-3
    ISSN 1546-3141 ; 0361-803X ; 0092-5381
    ISSN (online) 1546-3141
    ISSN 0361-803X ; 0092-5381
    DOI 10.2214/AJR.05.0969
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Esophageal rupture: Computed tomography with endoscopic correlation.

    Han, Nancy J / Silva, Alvin C / Decker, G Anton

    Radiology case reports

    2015  Volume 8, Issue 2, Page(s) 433

    Abstract: Boerhaave syndrome, or spontaneous rupture of the esophagus, is a complication of violent vomiting. Although the syndrome is rare, awareness of it is important because delayed or missed diagnosis can be fatal. Radiographic imaging, particularly computed ... ...

    Abstract Boerhaave syndrome, or spontaneous rupture of the esophagus, is a complication of violent vomiting. Although the syndrome is rare, awareness of it is important because delayed or missed diagnosis can be fatal. Radiographic imaging, particularly computed tomography, is the mainstay of diagnosis, and endoscopy generally does not play a role. We present a case of Boerhaave syndrome diagnosed by computed tomography that was complemented by endoscopic direct visualization to optimize surgical management. True Boerhaave syndrome is extremely rare, and rarer still is an endoscopic view of a known full-thickness tear of the esophagus.
    Language English
    Publishing date 2015-12-07
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.2484/rcr.v8i2.433
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  10. Article ; Online: Symptomatic right ventricular catheter embolization after Port-A-Cath manipulation.

    Nguyen, Vien X / Silva, Alvin C

    Journal of hospital medicine

    2010  Volume 5, Issue 2, Page(s) E17

    MeSH term(s) Cardiac Catheterization ; Catheters, Indwelling/adverse effects ; Equipment Failure ; Female ; Heart Ventricles/surgery ; Humans ; Middle Aged ; Pulmonary Embolism/etiology
    Language English
    Publishing date 2010-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2233783-0
    ISSN 1553-5606 ; 1553-5592
    ISSN (online) 1553-5606
    ISSN 1553-5592
    DOI 10.1002/jhm.554
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    Zs.MO 542: Show issues

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