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  1. Article: [:Q].

    Wei, Su-Jung / Chang, Hsiao-Yun / Chen, Shu-Ming / Yeh, Shu-Hui / Yang, Li-Hui

    Hu li za zhi The journal of nursing

    2019  Volume 66, Issue 6, Page(s) 33–42

    Abstract: ... used Q-sort to collect data. A 56-item "Nurse Practitioner Role Capacity Questionnaire" was used ...

    Abstract Background: The gap between the expectation and the development of role competency is a dilemma that nurse practitioners (NPs) face in clinical settings.
    Purpose: This study was designed to explore the perceived importance and actual practice of the role competencies of NPs and to compare the differences between the ideal and practical domains as well as related factors.
    Methods: This cross-sectional design study used Q-sort to collect data. A 56-item "Nurse Practitioner Role Capacity Questionnaire" was used as the research tool. Two questionnaires: Perceptions of Important Role Competencies and Actual Execution of Role Competencies were distributed to NPs twice, at times that were 2 weeks apart. A total of 40 participants were recruited, including 21(52.5%) internal medicine NPs and 19 (47.5%) surgical medicine NPs.
    Results: The significant differences that were identified in this study between the perceived importance and actual practice of role competencies were, by domain: medical assistance (t = -5.62, p < .001), clinical research (t = 4.14, p < .001), professional consultation (t = 2.29, p = .027), and direct care (t = 2.21, p = .033). The correlative factors for these differences were: education level (t = -2.17, p = .036) and membership in the Nurse Practitioner Association (t = -2.36, p = .017). NPs with higher levels of education and with membership in the Nurse Practitioner Association earned higher scores for self-expectation in important clinical competency.
    Conclusions: NPs face discrepancies in their role expectations, in important part due to their role as providers of medical assistance in clinical practical settings. NPs need to learn and demonstrate the roles and functions of advanced nursing practice to enhance nursing professionalism profoundly.
    MeSH term(s) Clinical Competence ; Cross-Sectional Studies ; Humans ; Nurse Practitioners/psychology ; Nurse's Role/psychology ; Q-Sort ; Surveys and Questionnaires
    Language Chinese
    Publishing date 2019-12-04
    Publishing country China (Republic : 1949- )
    Document type Journal Article
    ISSN 0047-262X
    ISSN 0047-262X
    DOI 10.6224/JN.201912_66(6).06
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Coenzyme Q

    Yang, Hsin-Ling / Lin, Ping-Yu / Vadivalagan, Chithravel / Lin, Yi-An / Lin, Kai-Yuan / Hseu, You-Cheng

    Archives of toxicology

    2023  Volume 97, Issue 4, Page(s) 1047–1068

    Abstract: Coenzyme Q ...

    Abstract Coenzyme Q
    MeSH term(s) Humans ; Adenosine Triphosphate ; Cadherins/genetics ; Cell Line, Tumor ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Inflammasomes ; Inflammation ; Interleukin-18 ; Lactate Dehydrogenase 5 ; Lactates ; Lipopolysaccharides ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; Triple Negative Breast Neoplasms/genetics ; Triple Negative Breast Neoplasms/metabolism ; Triple Negative Breast Neoplasms/pathology ; Ubiquinone/pharmacology
    Chemical Substances Adenosine Triphosphate (8L70Q75FXE) ; Cadherins ; cobaltous chloride (EVS87XF13W) ; Hypoxia-Inducible Factor 1, alpha Subunit ; Inflammasomes ; Interleukin-18 ; Lactate Dehydrogenase 5 (EC 1.1.1.27.-) ; Lactates ; Lipopolysaccharides ; NLR Family, Pyrin Domain-Containing 3 Protein ; Ubiquinone (1339-63-5) ; NLRP3 protein, human ; HIF1A protein, human
    Language English
    Publishing date 2023-02-27
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 124992-7
    ISSN 1432-0738 ; 0340-5761
    ISSN (online) 1432-0738
    ISSN 0340-5761
    DOI 10.1007/s00204-023-03456-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Coenzyme Q

    Hseu, You-Cheng / Tseng, Yu-Fang / Pandey, Sudhir / Shrestha, Sirjana / Lin, Kai-Yuan / Lin, Cheng-Wen / Lee, Chuan-Chen / Huang, Sheng-Teng / Yang, Hsin-Ling

    Oxidative medicine and cellular longevity

    2022  Volume 2022, Page(s) 4266214

    Abstract: Coenzyme Q (CoQ) analogs with a variable number of isoprenoid units have exhibited ...

    Abstract Coenzyme Q (CoQ) analogs with a variable number of isoprenoid units have exhibited as anti-inflammatory as well as antioxidant molecules. Using novel quinone derivative CoQ
    MeSH term(s) Adenosine Triphosphate/metabolism ; Animals ; Humans ; Inflammasomes/drug effects ; Lipopolysaccharides/metabolism ; Macrophages/metabolism ; Mice ; Mitophagy/immunology ; Transfection ; Ubiquinone/pharmacology ; Ubiquinone/therapeutic use
    Chemical Substances Inflammasomes ; Lipopolysaccharides ; Ubiquinone (1339-63-5) ; Adenosine Triphosphate (8L70Q75FXE)
    Language English
    Publishing date 2022-01-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2455981-7
    ISSN 1942-0994 ; 1942-0994
    ISSN (online) 1942-0994
    ISSN 1942-0994
    DOI 10.1155/2022/4266214
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Engineering high coenzyme Q

    Fan, Hang / Liu, Yan / Li, Chen-Yi / Jiang, Yan / Song, Jiao-Jiao / Yang, Lei / Zhao, Qing / Hu, Yong-Hong / Chen, Xiao-Ya / Xu, Jing-Jing

    Metabolic engineering

    2021  Volume 68, Page(s) 86–93

    Abstract: Coenzyme Q (CoQ) is vital for energy metabolism in living organisms. In humans, CoQ ...

    Abstract Coenzyme Q (CoQ) is vital for energy metabolism in living organisms. In humans, CoQ
    MeSH term(s) Carotenoids/metabolism ; Fruit/metabolism ; Humans ; Lycopersicon esculentum/genetics ; Mitochondria ; Ubiquinone/genetics
    Chemical Substances Ubiquinone (1339-63-5) ; Carotenoids (36-88-4)
    Language English
    Publishing date 2021-09-21
    Publishing country Belgium
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1470383-x
    ISSN 1096-7184 ; 1096-7176
    ISSN (online) 1096-7184
    ISSN 1096-7176
    DOI 10.1016/j.ymben.2021.09.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Online: Q-Diffusion

    Li, Xiuyu / Liu, Yijiang / Lian, Long / Yang, Huanrui / Dong, Zhen / Kang, Daniel / Zhang, Shanghang / Keutzer, Kurt

    Quantizing Diffusion Models

    2023  

    Abstract: ... The code is available at https://github.com/Xiuyu-Li/q-diffusion ...

    Abstract Diffusion models have achieved great success in image synthesis through iterative noise estimation using deep neural networks. However, the slow inference, high memory consumption, and computation intensity of the noise estimation model hinder the efficient adoption of diffusion models. Although post-training quantization (PTQ) is considered a go-to compression method for other tasks, it does not work out-of-the-box on diffusion models. We propose a novel PTQ method specifically tailored towards the unique multi-timestep pipeline and model architecture of the diffusion models, which compresses the noise estimation network to accelerate the generation process. We identify the key difficulty of diffusion model quantization as the changing output distributions of noise estimation networks over multiple time steps and the bimodal activation distribution of the shortcut layers within the noise estimation network. We tackle these challenges with timestep-aware calibration and split shortcut quantization in this work. Experimental results show that our proposed method is able to quantize full-precision unconditional diffusion models into 4-bit while maintaining comparable performance (small FID change of at most 2.34 compared to >100 for traditional PTQ) in a training-free manner. Our approach can also be applied to text-guided image generation, where we can run stable diffusion in 4-bit weights with high generation quality for the first time.

    Comment: The code is available at https://github.com/Xiuyu-Li/q-diffusion
    Keywords Computer Science - Computer Vision and Pattern Recognition ; Computer Science - Machine Learning
    Publishing date 2023-02-08
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Coenzyme Q

    Yang, Hsin-Ling / Tsai, Chia-Hsuan / Shrestha, Sirjana / Lee, Chuan-Chen / Liao, Jiunn-Wang / Hseu, You-Cheng

    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

    2021  Volume 155, Page(s) 112384

    Abstract: Coenzyme Q ...

    Abstract Coenzyme Q
    MeSH term(s) Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Apoptosis/drug effects ; Autophagy/drug effects ; Benzoquinones/pharmacology ; Benzoquinones/therapeutic use ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Female ; Glioblastoma/drug therapy ; Glioblastoma/metabolism ; Humans ; Mice, Inbred BALB C ; Mice, Nude ; Necrosis/chemically induced ; Polyporales/chemistry ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects ; Xenograft Model Antitumor Assays ; Mice
    Chemical Substances Antineoplastic Agents ; Benzoquinones ; Reactive Oxygen Species ; ubiquinone-O (605-94-7)
    Language English
    Publishing date 2021-07-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 782617-5
    ISSN 1873-6351 ; 0278-6915
    ISSN (online) 1873-6351
    ISSN 0278-6915
    DOI 10.1016/j.fct.2021.112384
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The in vitro and in vivo depigmentation activity of coenzyme Q

    Hseu, You-Cheng / Yeh, Jou-Tsen / Vadivalagan, Chithravel / Chen, Siang-Jyun / Gowrisankar, Yugandhar Vudhya / Pandey, Sudhir / Hsu, Yuan-Tai / Yen, Hung-Rong / Huang, Hui-Chi / Hseu, Jhih-Hsuan / Yang, Hsin-Ling

    Cell communication and signaling : CCS

    2024  Volume 22, Issue 1, Page(s) 151

    Abstract: Background: Coenzyme Q: Methods: We resolved the depigmenting efficiency of CoQ: Results ...

    Abstract Background: Coenzyme Q
    Methods: We resolved the depigmenting efficiency of CoQ
    Results: CoQ
    Conclusions: Our results showed that CoQ
    MeSH term(s) Animals ; Humans ; Ubiquinone/pharmacology ; Ubiquinone/metabolism ; Melanins/metabolism ; Zebrafish/metabolism ; Monophenol Monooxygenase/metabolism ; alpha-MSH/metabolism ; Beclin-1/metabolism ; Melanocytes/metabolism ; Keratinocytes/metabolism ; Autophagy ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Cell Line, Tumor ; Benzoquinones ; Polyporales
    Chemical Substances Ubiquinone (1339-63-5) ; Melanins ; Monophenol Monooxygenase (EC 1.14.18.1) ; alpha-MSH (581-05-5) ; Beclin-1 ; quinone (3T006GV98U) ; Proto-Oncogene Proteins c-bcl-2 ; Benzoquinones
    Language English
    Publishing date 2024-02-26
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2126315-2
    ISSN 1478-811X ; 1478-811X
    ISSN (online) 1478-811X
    ISSN 1478-811X
    DOI 10.1186/s12964-024-01537-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Self-Q-switched Er:Lu

    Zhang, Meng / Yin, Yanru / Zhang, Lu / Zhang, Baitao / Yang, Kejian / He, Jingliang / Li, Tao

    Applied optics

    2023  Volume 62, Issue 6, Page(s) 1462–1466

    Abstract: A diode-pumped self-Q-switched 2.74 µm Er:Lu ...

    Abstract A diode-pumped self-Q-switched 2.74 µm Er:Lu
    Language English
    Publishing date 2023-02-13
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.481607
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: UPLC-Q-TOF-MS/MS Analysis of

    Wang, Yan-Duo / Yang, Jian / Li, Qi / Li, Yuan-Yuan / Tan, Xiang-Mei / Yao, Si-Yang / Niu, Shu-Bin / Deng, Hui / Guo, Lan-Ping / Ding, Gang

    Frontiers in microbiology

    2022  Volume 13, Page(s) 807014

    Abstract: ... ...

    Abstract Seco
    Language English
    Publishing date 2022-03-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2022.807014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Antrodia camphorata and coenzyme Q

    Yang, Hsin-Ling / Chang, Yao-Hsien / Pandey, Sudhir / Bhat, Asif Ali / Vadivalagan, Chithravel / Lin, Kai-Yuan / Hseu, You-Cheng

    Environmental toxicology

    2023  Volume 38, Issue 7, Page(s) 1548–1564

    Abstract: Antrodia camphorata (AC) and Coenzyme Q ...

    Abstract Antrodia camphorata (AC) and Coenzyme Q
    MeSH term(s) Humans ; Animals ; Mice ; beta Catenin/metabolism ; Ubiquinone/pharmacology ; Vimentin/metabolism ; Epithelial-Mesenchymal Transition ; Glioblastoma/drug therapy ; Neoplasm Invasiveness/pathology ; Cadherins/genetics ; Cell Line, Tumor ; Hypoxia-Inducible Factor 1, alpha Subunit ; Cell Movement
    Chemical Substances beta Catenin ; Ubiquinone (1339-63-5) ; Vimentin ; Cadherins ; quinone (3T006GV98U) ; Hypoxia-Inducible Factor 1, alpha Subunit
    Language English
    Publishing date 2023-03-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1463449-1
    ISSN 1522-7278 ; 1520-4081
    ISSN (online) 1522-7278
    ISSN 1520-4081
    DOI 10.1002/tox.23785
    Database MEDical Literature Analysis and Retrieval System OnLINE

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