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Book ; Thesis: Tenax- vs. Nir-Stent-Studie (TENISS)

Sattler, Katherine

2003

Author's details	vorgelegt von Katherine Sattler
Language	German
Size	66 S. : Ill., graph. Darst., 21 cm
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Frankfurt (Main), Univ., Diss., 2004
HBZ-ID	HT014487253
Database	Catalogue ZB MED Medicine, Health

In stock of ZB MED Cologne/Königswinter

Shelf mark	Loan status	Location
2004 D 1496	order for loan	Magazin

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Article: Temporal regulation of the Mediator complex during muscle proliferation, differentiation, regeneration, aging, and disease.

Kolonay, Dominic W / Sattler, Kristina M / Strawser, Corinne / Rafael-Fortney, Jill / Mihaylova, Maria M / Miller, Katherine E / Lepper, Christoph / Baskin, Kedryn K

Frontiers in cell and developmental biology

2024 Volume 12, Page(s) 1331563

Abstract: Genesis of skeletal muscle relies on the differentiation and fusion of mono-nucleated muscle progenitor cells into the multi-nucleated muscle fiber syncytium. The temporally-controlled cellular and morphogenetic changes underlying this process are ... ...

Abstract	Genesis of skeletal muscle relies on the differentiation and fusion of mono-nucleated muscle progenitor cells into the multi-nucleated muscle fiber syncytium. The temporally-controlled cellular and morphogenetic changes underlying this process are initiated by a series of highly coordinated transcription programs. At the core, the myogenic differentiation cascade is driven by muscle-specific transcription factors, i.e., the Myogenic Regulatory Factors (MRFs). Despite extensive knowledge on the function of individual MRFs, very little is known about how they are coordinated. Ultimately, highly specific coordination of these transcription programs is critical for their masterfully timed transitions, which in turn facilitates the intricate generation of skeletal muscle fibers from a naïve pool of progenitor cells. The Mediator complex links basal transcriptional machinery and transcription factors to regulate transcription and could be the integral component that coordinates transcription factor function during muscle differentiation, growth, and maturation. In this study, we systematically deciphered the changes in Mediator complex subunit expression in skeletal muscle development, regeneration, aging, and disease. We incorporated our
Language	English
Publishing date	2024-04-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2737824-X
ISSN	2296-634X
ISSN	2296-634X
DOI	10.3389/fcell.2024.1331563
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Protocol for a study on vicarious resilience in service providers for victims and survivors of violence.

Ferns, Alyssa / Roebuck, Benjamin S / McGlinchey, Diana / Sattler, Patricia L / Scott, Hannah / Killian, Kyle D / Bedard, Theresia / Boileau, Amy / Tague, Connor / Thompson, Katherine

PloS one

2023 Volume 18, Issue 3, Page(s) e0283474

Abstract: Few national studies examine victim service providers (VSPs), the important work that they do, and the resources and strategies contributing to their wellness at work. The proposed study aims to investigate the vicarious resilience of those working ... ...

Abstract	Few national studies examine victim service providers (VSPs), the important work that they do, and the resources and strategies contributing to their wellness at work. The proposed study aims to investigate the vicarious resilience of those working within the Canadian victim services sector. Participants will be asked about the ways in which they have changed and experienced resilience through exposure to supporting their clients, in addition to the challenges and barriers that still exist. A mixed-methods study incorporating an online survey, virtual focus groups, and semi-structured in-depth interviews will explore job satisfaction, compassion fatigue, turnover intention, instances of workplace microaggressions, vicarious resilience, coping strategies and self-care of VSP participants. The results will contribute to the literature on themes related to the wellness of VSPs. Dissemination of results will provide a Canadian perspective on organizational wellness, including challenges encountered as a result of COVID-19, working conditions that require further advocacy, and emerging perspectives on protective factors.
MeSH term(s)	Humans ; COVID-19/epidemiology ; Canada ; Violence ; Adaptation, Psychological ; Survivors
Language	English
Publishing date	2023-03-23
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0283474
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Flagellin-Induced Immune Response in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Yuecel, Goekhan / Zhou, Xiaobo / Terkatz, Linda / Wendel, Angela / Reinhardt, Julius / El-Battrawy, Ibrahim / Sattler, Katherine / Cyganek, Lukas / Utikal, Jochen / Langer, Harald / Scharf, Ruediger / Duerschmied, Daniel / Akin, Ibrahim

International journal of molecular sciences

2023 Volume 24, Issue 18

Abstract: Pathogen-associated molecular patterns (PAMPs) are involved in the pathogenesis of septic cardiomyopathy through a toll-like receptor (TLR)-mediated immune response. Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) can reflect the ... ...

Abstract	Pathogen-associated molecular patterns (PAMPs) are involved in the pathogenesis of septic cardiomyopathy through a toll-like receptor (TLR)-mediated immune response. Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) can reflect the innate immune abilities of cardiomyocytes. Therefore, hiPSC-CMs may provide an attractive tool with which to study PAMP-induced alterations in cardiomyocytes. HiPSC-CMs from two different healthy donors were exposed to the PAMP flagellin (FLA) at different doses and exposure times. Alterations in the expression levels of distinct inflammation-associated cytokines, intracellular inflammation pathways including TLR5 downstream signaling, reactive oxygen species levels and surface antigen composition were assessed using PCR, ELISA and FACS techniques. Higher doses of flagellin increased the expression levels of inflammation-associated cytokines like TNFα (
MeSH term(s)	Humans ; Flagellin/pharmacology ; Induced Pluripotent Stem Cells ; Myocytes, Cardiac ; Toll-Like Receptor 5/genetics ; Immunity, Innate ; Cytokines ; Inflammation
Chemical Substances	Flagellin (12777-81-0) ; Toll-Like Receptor 5 ; Cytokines
Language	English
Publishing date	2023-09-11
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms241813933
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Protocol for a study on vicarious resilience in service providers for victims and survivors of violence.

Alyssa Ferns / Benjamin S Roebuck / Diana McGlinchey / Patricia L Sattler / Hannah Scott / Kyle D Killian / Theresia Bedard / Amy Boileau / Connor Tague / Katherine Thompson

PLoS ONE, Vol 18, Iss 3, p e

2023 Volume 0283474

Abstract	Few national studies examine victim service providers (VSPs), the important work that they do, and the resources and strategies contributing to their wellness at work. The proposed study aims to investigate the vicarious resilience of those working within the Canadian victim services sector. Participants will be asked about the ways in which they have changed and experienced resilience through exposure to supporting their clients, in addition to the challenges and barriers that still exist. A mixed-methods study incorporating an online survey, virtual focus groups, and semi-structured in-depth interviews will explore job satisfaction, compassion fatigue, turnover intention, instances of workplace microaggressions, vicarious resilience, coping strategies and self-care of VSP participants. The results will contribute to the literature on themes related to the wellness of VSPs. Dissemination of results will provide a Canadian perspective on organizational wellness, including challenges encountered as a result of COVID-19, working conditions that require further advocacy, and emerging perspectives on protective factors.
Keywords	Medicine ; R ; Science ; Q
Subject code	360
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Protocol for a study on vicarious resilience in service providers for victims and survivors of violence

Alyssa Ferns / Benjamin S. Roebuck / Diana McGlinchey / Patricia L. Sattler / Hannah Scott / Kyle D. Killian / Theresia Bedard / Amy Boileau / Connor Tague / Katherine Thompson

PLoS ONE, Vol 18, Iss

2023 Volume 3

Abstract	Few national studies examine victim service providers (VSPs), the important work that they do, and the resources and strategies contributing to their wellness at work. The proposed study aims to investigate the vicarious resilience of those working within the Canadian victim services sector. Participants will be asked about the ways in which they have changed and experienced resilience through exposure to supporting their clients, in addition to the challenges and barriers that still exist. A mixed-methods study incorporating an online survey, virtual focus groups, and semi-structured in-depth interviews will explore job satisfaction, compassion fatigue, turnover intention, instances of workplace microaggressions, vicarious resilience, coping strategies and self-care of VSP participants. The results will contribute to the literature on themes related to the wellness of VSPs. Dissemination of results will provide a Canadian perspective on organizational wellness, including challenges encountered as a result of COVID-19, working conditions that require further advocacy, and emerging perspectives on protective factors.
Keywords	Medicine ; R ; Science ; Q
Subject code	360
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Orbital Angular Momentum from Self-Assembled Concentric Nanoparticle Rings.

Vargo, Emma / Evans, Katherine M / Wang, Qingjun / Sattler, Andrew / Qian, Yiwen / Yao, Jie / Xu, Ting

Advanced materials (Deerfield Beach, Fla.)

2021 Volume 33, Issue 40, Page(s) e2103563

Abstract: Ring-shaped nanostructures can focus, filter, and manipulate electromagnetic waves, but are challenging to incorporate into devices using standard nanofabrication techniques. Directed self-assembly (DSA) of block copolymers (BCPs) on lithographically ... ...

Abstract	Ring-shaped nanostructures can focus, filter, and manipulate electromagnetic waves, but are challenging to incorporate into devices using standard nanofabrication techniques. Directed self-assembly (DSA) of block copolymers (BCPs) on lithographically patterned templates has successfully been used to fabricate concentric rings and spirals as etching masks. However, this method is limited by BCP phase behavior and material selection. Here, a straightforward approach to generate ring-shaped nanoparticle assemblies in thin films of supramolecular nanocomposites is demonstrated. DSA is used to guide the formation of concentric rings with radii spanning 150-1150 nm and ring widths spanning 30-60 nm. When plasmonic nanoparticles are used, ring nanodevice arrays can be fabricated in one step, and the completed devices produce high-quality orbital angular momentum (OAM). Nanocomposite DSA simplifies and streamlines nanofabrication by producing metal structures without etching or deposition steps; it also introduces interparticle coupling as a new design axis. Detailed analysis of the nanoparticle ring assemblies confirms that the supramolecular system self-regulates the spatial distribution of its components, and thus exhibits a degree of flexibility absent in DSA of BCPs alone, where structures are determined by polymer-pattern incommensurability. The present studies also provide guidelines for developing self-regulating DSA as an alternative to incommensurability-driven methods.
Language	English
Publishing date	2021-08-21
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1474949-X
ISSN	1521-4095 ; 0935-9648
ISSN (online)	1521-4095
ISSN	0935-9648
DOI	10.1002/adma.202103563
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Comparison of the prognosis and outcome of heart failure with reduced ejection fraction patients treated with sacubitril/valsartan according to age.

Abumayyaleh, Mohammad / El-Battrawy, Ibrahim / Kummer, Marvin / Pilsinger, Christina / Sattler, Katherine / Kuschyk, Jürgen / Aweimer, Assem / Mügge, Andreas / Borggrefe, Martin / Akin, Ibrahim

Future cardiology

2021 Volume 17, Issue 6, Page(s) 1131–1142

Abstract: The treatment with sacubitril/valsartan in patients suffering from chronic heart failure with reduced ejection fraction increases left ventricular ejection fraction and decreases the risk of sudden cardiac death. We conducted a retrospective analysis ... ...

Abstract	The treatment with sacubitril/valsartan in patients suffering from chronic heart failure with reduced ejection fraction increases left ventricular ejection fraction and decreases the risk of sudden cardiac death. We conducted a retrospective analysis regarding the impact of age differences on the treatment outcome of sacubitril/valsartan in patients with chronic heart failure with reduced ejection fraction. Patients were defined as adults if ≤65 years (n = 51) and older if >65 years of age (n = 76). The incidence of ventricular arrhythmias at 1-year follow-up was comparable in both groups (30.8 vs 26.5%; p = 0.71). The mortality rate in adult patients is significantly lower as compared with older patients (2 vs 14.5%; log-rank = 0.04). Older patients may suffer remarkably more side effects than adult patients (21.1 vs 11.8%; p = 0.03).
MeSH term(s)	Adult ; Aminobutyrates/therapeutic use ; Angiotensin Receptor Antagonists/therapeutic use ; Biphenyl Compounds ; Drug Combinations ; Heart Failure/drug therapy ; Heart Failure/epidemiology ; Humans ; Prognosis ; Retrospective Studies ; Stroke Volume ; Tetrazoles/therapeutic use ; Treatment Outcome ; Valsartan ; Ventricular Function, Left
Chemical Substances	Aminobutyrates ; Angiotensin Receptor Antagonists ; Biphenyl Compounds ; Drug Combinations ; Tetrazoles ; sacubitril (17ERJ0MKGI) ; Valsartan (80M03YXJ7I)
Language	English
Publishing date	2021-03-18
Publishing country	England
Document type	Journal Article
ZDB-ID	2274267-0
ISSN	1744-8298 ; 1479-6678
ISSN (online)	1744-8298
ISSN	1479-6678
DOI	10.2217/fca-2020-0213
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: TRPV1 activation and internalization is part of the LPS-induced inflammation in human iPSC-derived cardiomyocytes.

Sattler, Katherine / El-Battrawy, Ibrahim / Cyganek, Lukas / Lang, Siegfried / Lan, Huan / Li, Xin / Zhao, Zhihan / Utikal, Jochen / Wieland, Thomas / Borggrefe, Martin / Zhou, Xiaobo / Akin, Ibrahim

Scientific reports

2021 Volume 11, Issue 1, Page(s) 14689

Abstract: The non-selective cation channel transient receptor potential vanilloid 1 (TRPV1) is expressed throughout the cardiovascular system. Recent evidence shows a role for TRPV1 in inflammatory processes. The role of TRPV1 for myocardial inflammation has not ... ...

Abstract	The non-selective cation channel transient receptor potential vanilloid 1 (TRPV1) is expressed throughout the cardiovascular system. Recent evidence shows a role for TRPV1 in inflammatory processes. The role of TRPV1 for myocardial inflammation has not been established yet. Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes (hiPSC-CM) from 4 healthy donors were incubated with lipopolysaccharides (LPS, 6 h), TRPV1 agonist capsaicin (CAP, 20 min) or the antagonist capsazepine (CPZ, 20 min). TRPV1 expression was studied by PCR and western blotting. TRPV1 internalization was analyzed by immunofluorescence. Interleukin-6 (IL-6) secretion and phosphorylation of JNK, p38 and ERK were determined by ELISA. TRPV1-associated ion channel current was measured by patch clamp. TRPV1-mRNA and -protein were expressed in hiPSC-CM. TRPV1 was localized in the plasma membrane. LPS significantly increased secretion of IL-6 by 2.3-fold, which was prevented by pre-incubation with CPZ. LPS induced TRPV1 internalization. Phosphorylation levels of ERK, p38 or JNK were not altered by TRPV1 stimulation or inhibition. LPS and IL-6 significantly lowered TRPV1-mediated ion channel current. TRPV1 mediates the LPS-induced inflammation in cardiomyocytes, associated with changes of cellular electrophysiology. LPS-induced inflammation results in TRPV1 internalization. Further studies have to examine the underlying pathways and the clinical relevance of these findings.
MeSH term(s)	Cells, Cultured ; Humans ; Induced Pluripotent Stem Cells/drug effects ; Induced Pluripotent Stem Cells/metabolism ; Induced Pluripotent Stem Cells/physiology ; Inflammation/chemically induced ; Inflammation/genetics ; Inflammation/metabolism ; Inflammation/pathology ; Interleukin-6/metabolism ; Lipopolysaccharides ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/pathology ; Myocytes, Cardiac/physiology ; Signal Transduction/drug effects ; TRPV Cation Channels/agonists ; TRPV Cation Channels/genetics ; TRPV Cation Channels/metabolism
Chemical Substances	Interleukin-6 ; Lipopolysaccharides ; TRPV Cation Channels ; TRPV1 protein, human
Language	English
Publishing date	2021-07-19
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-021-93958-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Treating the Lips and Its Anatomical Correlate in Respect to Vascular Compromise.

Ghannam, Sahar / Sattler, Sonja / Frank, Konstantin / Freytag, David L / Webb, Katherine L / Devineni, Aditya / Cotofana, Sebastian

Facial plastic surgery : FPS

2019 Volume 35, Issue 2, Page(s) 193–203

Abstract: Treating the lips to increase facial attractiveness and youthfulness is challenging when trying to consider ethnic differences in an increasingly more diverse society. Multiple injection techniques are currently available for treating lip contour and ... ...

Abstract	Treating the lips to increase facial attractiveness and youthfulness is challenging when trying to consider ethnic differences in an increasingly more diverse society. Multiple injection techniques are currently available for treating lip contour and volume, but a validation in the cadaveric model under the aspects of safety has not been performed yet. The injection techniques presented in this study are based on the experience and personal selection of the authors. The authors have assessed, treated, and evaluated for more than 20 years patients from the Middle East and Central Europe. Cadaveric verification was performed for each of the presented techniques to identify the positioning of the injected product inside the lips and its relation to the superior/inferior labial arteries. The results of the anatomic analyses revealed that in 58.3% of the performed injections, the product was placed close to the superior/inferior labial arteries. In 60.0% of the cases, applications using a needle placed the injected product in endangered locations, whereas 57.1% of the cases using cannulas placed the product in endangered locations (i.e., in the vicinity of the superior/inferior labial arteries). This anatomic study revealed that injected material into the lips is frequently placed in close proximity to labial arteries representing a high risk for intra-arterial applications, leading to tissue loss (necrosis) and potential end-arterial embolism (potential blindness). Nevertheless, treatment of the lips should be a multistep approach focusing first on the far (upper and middle face) and close (labiomandibular and labiomental) perioral regions.
MeSH term(s)	Cosmetic Techniques ; Europe ; Face ; Humans ; Lip ; Middle East
Language	English
Publishing date	2019-04-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	630090-x
ISSN	1098-8793 ; 0736-6825
ISSN (online)	1098-8793
ISSN	0736-6825
DOI	10.1055/s-0039-1683856
Database	MEDical Literature Analysis and Retrieval System OnLINE

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