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Article: New Insurance Product Needed for Physicians: Coverage for Sham Peer Review and Hospital Immunity.

Gruessner, Rainer W G / Poston, Robert / Gharagozloo, Farid

Journal of insurance medicine (New York, N.Y.)

2024 Volume 50, Issue 2, Page(s) 150–153

Abstract: This commentary article highlights the need for an insurance product for hospital-employed physicians that provides coverage against sham peer review and a complete defense against wrongful hospital allegations of incompetent, whistleblowing, or ... ...

Abstract	This commentary article highlights the need for an insurance product for hospital-employed physicians that provides coverage against sham peer review and a complete defense against wrongful hospital allegations of incompetent, whistleblowing, or disruptive behavior.
MeSH term(s)	Humans ; Insurance ; Hospitals ; Physicians ; Peer Review ; Whistleblowing
Language	English
Publishing date	2024-02-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2276848-8
ISSN	0743-6661
ISSN	0743-6661
DOI	10.17849/insm-50-2-150-153.1
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Article ; Online: Effect of pomegranate seed oil on egg production, egg quality and yolk fatty acid deposition in laying hen.

Gharagozloo, Alireza / Kheiri, Farshid / Nasr, Javad / Faghani, Mostafa

Veterinary medicine and science

2023 Volume 9, Issue 6, Page(s) 2755–2762

Abstract: Background: Pomegranate seed oil (PSO) contains punicic acid as well as conjugated linolenic acid isomers, including α-eleostearic and catalpic acids, along with phytosterols, especially β-sitosterol, campesterol and stigmasterol, with lipotropic impact ...

Abstract	Background: Pomegranate seed oil (PSO) contains punicic acid as well as conjugated linolenic acid isomers, including α-eleostearic and catalpic acids, along with phytosterols, especially β-sitosterol, campesterol and stigmasterol, with lipotropic impact and egg fortifying effect in laying hens. Objectives: The present experiment was designed to examine the effects of PSO on egg production, egg quality, blood lipids and yolk fatty acid deposition in laying hens. Methods: A total of 360 Hy-line laying hens (w-80), at 25 weeks of age, were randomly allotted to five dietary treatments in a completely randomized design during a 10-week period. Experimental treatments consisted of a basal diet or supplementation of 1, 2, 3 and 4 g PSO/kg to basal diet. Performance indicators and fatty acid composition of egg yolk were evaluated during different experimental periods. Blood lipid attributes were evaluated at the end of the experiment. Results: Dietary supplementation of 4 g PSO/kg feed increased daily feed intake and egg production rate of laying hens (p < 0.05). There was not any significant influence of experimental treatments on egg quality, whereas an increasing trend observed in egg yolk colour of hens received dietary graded levels of PSO. Dietary supplemental 4 g/kg PSO increased the proportion of yolk poly-unsaturated fatty acid (PUFA) concentration (p < 0.05). Furthermore, the PUFA to saturated fatty acid ratio increased after dietary supplementation of 1 or 4 g/kg PSO (p < 0.05). Serum concentration of cholesterol, triacylglycerol and low-density lipoprotein decreased in response to the supplementation of more than 3 g PSO/kg in the feed (p < 0.05). Conclusions: In conclusion, dietary supplementation with 4 g/kg PSO improved production rate and decreased blood lipids in laying hens. Moreover, dietary supplemental PSO modified yolk fatty acid deposition without detrimental effects on the egg quality.
MeSH term(s)	Animals ; Female ; Fatty Acids ; Chickens/physiology ; Pomegranate ; Dietary Supplements ; Plant Oils/pharmacology
Chemical Substances	Fatty Acids ; Plant Oils
Language	English
Publishing date	2023-10-17
Publishing country	England
Document type	Journal Article
ZDB-ID	2819409-3
ISSN	2053-1095 ; 2053-1095
ISSN (online)	2053-1095
ISSN	2053-1095
DOI	10.1002/vms3.1296
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Article: Development of the fundamentals of thoracic robotic surgery curriculum.

Levy, Jeffrey S / Gharagozloo, Farid

Journal of thoracic disease

2021 Volume 13, Issue 10, Page(s) 6116–6122

Abstract: A great technological revolution in surgery occurred with the introduction of laparoscopic and other minimally invasive procedures, with enormous patient benefits. Robotic-assisted surgery (RAS) is a form of minimally invasive surgery that overcomes some ...

Abstract	A great technological revolution in surgery occurred with the introduction of laparoscopic and other minimally invasive procedures, with enormous patient benefits. Robotic-assisted surgery (RAS) is a form of minimally invasive surgery that overcomes some of the limitations of laparoscopic techniques. Until recently, there were few standardized curricula for RAS. The Fundamentals of Robotic (FRS) developed a process through expert consensus conferences to develop an effective and validated curriculum for basic robotic surgery. A specialty specific curriculum for thoracic robotic surgery is also needed. The Fundamentals of Thoracic Robotic Surgery (FTRS) Consensus Conference brought together expert thoracic surgeons to build upon the accomplishments of FRS and incorporate the experiences of thoracic societies and academic institutions to establish a standardized FTRS curriculum for the development and maintenance of specialty-specific robotic surgical skills. A task deconstruction was completed for the thoracic 'signature' procedure, the lobectomy and training items and potential errors were identified for each step of the procedure. A final outline of the FTRS curriculum was developed during the conference and physical and virtual reality thoracic surgery training models were discussed. Following the conference, the steering committee completed the FTRS curriculum with editorial review from all stakeholders. The FTRS consensus conference followed the validated FRS model but in an accelerated process due to important groundwork set by experts in the FRS consensus conferences. A full online curriculum and supporting psychomotor skills training and team communication has been developed for the lobectomy procedure.
Language	English
Publishing date	2021-11-03
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	2573571-8
ISSN	2077-6624 ; 2072-1439
ISSN (online)	2077-6624
ISSN	2072-1439
DOI	10.21037/jtd-2019-rts-02
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Article ; Online: Effect of Advanced Glycation end Products (AGEs) on Sperm Parameters and Function in C57Bl/6 Mice.

Darmishonnejad, Zahra / Zadeh, Vahideh Hassan / Tavalaee, Marziyeh / Kobarfard, Farzad / Hassani, Mahsa / Gharagozloo, Parviz / Drevet, Joël R / Nasr-Esfahani, Mohammad Hossein

Reproductive sciences (Thousand Oaks, Calif.)

2024

Abstract: This study investigated the deleterious impact of advanced glycation end products (AGEs), commonly present in metabolic disorders like diabetes, obesity, and infertility-related conditions, on sperm structure and function using a mouse model where AGE ... ...

Abstract	This study investigated the deleterious impact of advanced glycation end products (AGEs), commonly present in metabolic disorders like diabetes, obesity, and infertility-related conditions, on sperm structure and function using a mouse model where AGE generation was heightened through dietary intervention. Five-week-old C57BL/6 mice were divided into two groups, one on a regular diet (control) and the other on an AGE-rich diet. After 13 weeks, various parameters were examined, including fasting blood glucose, body weight, food consumption, sperm parameters and function, testicular superoxide dismutase levels, malondialdehyde content, total antioxidant capacity, Johnson score, AGE receptor (RAGE) content, and carboxymethyl lysine (CML) content. The results showed that mice in the AGE group exhibited increased body weight and elevated fasting blood glucose levels. Furthermore, the AGE group displayed adverse effects on sperm, including reduced sperm counts, motility, increased morphological abnormalities, residual histone, protamine deficiency, sperm DNA fragmentation, reduced testicular antioxidant capacity, and higher levels of RAGE and CML proteins. These findings underscore the negative impact of AGEs on male reproductive health, particularly within the context of metabolic disorders, emphasizing the crucial role of the AGE/RAGE axis in male infertility, especially in the context of Western dietary patterns.
Language	English
Publishing date	2024-03-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	2276411-2
ISSN	1933-7205 ; 1933-7191
ISSN (online)	1933-7205
ISSN	1933-7191
DOI	10.1007/s43032-024-01507-w
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Article: Robotic Staged Bilateral Selective Postganglionic Sympathectomy for Upper-Extremity Hyperhidrosis.

Gharagozloo, Farid / Meyer, Mark / Tempesta, Barbara

Surgical technology international

2020 Volume 36, Page(s) 265–269

Abstract: Purpose: The prevalence of compensatory hyperhidrosis (CH) has been reported to be as high as 80% in patients following thoracic sympathectomy for upper-extremity hyperhidrosis. The CH rate is 7.2% with simultaneous bilateral robotic selective dorsal ... ...

Abstract	Purpose: The prevalence of compensatory hyperhidrosis (CH) has been reported to be as high as 80% in patients following thoracic sympathectomy for upper-extremity hyperhidrosis. The CH rate is 7.2% with simultaneous bilateral robotic selective dorsal sympathectomy. We reviewed the results in patients who underwent staged bilateral robotic selective dorsal sympathectomy (SBRSS). Methods: A case series analysis of patients who underwent SBRSS was performed. A surgical robot was used to divide the postganglionic sympathetic fibers and communicating rami to intercostal nerves 2, 3, and 4. The sympathetic chain was left intact. The operation was performed on the dominant side, and the same procedure was then performed on the contralateral side after 4 weeks. The success of the sympathectomy was determined by intraoperative temperature measurement, patient interviews, and the Hyperhidrosis Disease Severity Scale. Results: There were 47 patients (22 men, 25 women), with a mean age of 22 ± 3 years. Minor complications were seen in 4% of patients. One patient had transient heart block. One patient had transient partial Horner's syndrome. Forty percent of patients had transient CH after the first surgery, and 45% had transient CH after sympathectomy on the contralateral side. There were no deaths. The median hospitalization was 3 days. At a mean follow-up of 28 ± 6 months, 46/47 patients (98%) had sustained relief of hyperhidrosis. In one patient (1/47, 2%), hyperhidrosis recurred on the first operated side. One patient (2%) exhibited sustained CH. Conclusion: SBRSS is associated with a lower rate of CH than when the procedure is performed bilaterally in a simultaneous fashion. This procedure is associated with the lowest reported rate of CH.
MeSH term(s)	Adult ; Female ; Humans ; Hyperhidrosis ; Male ; Retrospective Studies ; Robotic Surgical Procedures ; Sympathectomy ; Treatment Outcome ; Young Adult
Language	English
Publishing date	2020-04-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	1225512-9
ISSN	1090-3941
ISSN	1090-3941
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Article: Robotic Lobectomy: Experience with 638 Consecutive Cases.

Gharagozloo, Farid / Meyer, Mark / Tempesta, Barbara

Surgical technology international

2020 Volume 36, Page(s) 251–256

Abstract: Background: Robotic lobectomy has been evolving over the past decade and has been shown to be an oncologically acceptable procedure. We evaluated our experience with robotic lobectomy for the treatment of early-stage lung cancer.: Methods: We ... ...

Abstract	Background: Robotic lobectomy has been evolving over the past decade and has been shown to be an oncologically acceptable procedure. We evaluated our experience with robotic lobectomy for the treatment of early-stage lung cancer. Methods: We performed a retrospective review of prospectively accrued patients at our institution who underwent robotic lobectomy for early-stage lung cancer from February 2004 to July 2019, RESULTS: Of 3304 consecutive patients who underwent a robotic operation by a single surgeon, 638 underwent robotic lobectomy for early-stage primary non-small cell lung cancer (NSCLC; stages I and II). The 427 (67%) men and 211 (33%) women had a median age of 69 y (range 41-86), and 567 (89 %) were former or current smokers. The median operative time was 176 minutes (range 160-456), the median chest tube time was 3 days (2-8), the median air leak time was 0 days (0-3), and the median length of stay was 3 days (1-26). The median tumor size was 2.6 cm (range 06-3.4). The mean number of nodes recovered was 14 ± 3. Pathologic upstaging was noted in 121 patients (19%). Minor complications were observed in 133 patients (21%). Conversion to thoracotomy occurred in 11 (1.7%) patients. Mortality was 0.5%. Conclusion: Robotic lobectomy is a safe, minimally invasive procedure that replicates the oncologic and technical principles of thoracotomy for the treatment of lung cancer.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Carcinoma, Non-Small-Cell Lung/surgery ; Female ; Humans ; Lung Neoplasms/surgery ; Male ; Middle Aged ; Pneumonectomy ; Retrospective Studies ; Robotic Surgical Procedures ; Thoracic Surgery, Video-Assisted ; Treatment Outcome
Language	English
Publishing date	2020-01-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	1225512-9
ISSN	1090-3941
ISSN	1090-3941
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Article: Robotic First Rib Resection for Thoracic Outlet Syndrome.

Gharagozloo, Farid / Meyer, Mark / Tempesta, Barbara / Werden, Scott

Surgical technology international

2020 Volume 36, Page(s) 239–244

Abstract: Purpose: First rib resection is a key component of the treatment of Thoracic Outlet Syndrome (TOS). We report our experience with, and technique for, robotic first rib resection.: Methods: Patients diagnosed with TOS underwent robotic first rib ... ...

Abstract	Purpose: First rib resection is a key component of the treatment of Thoracic Outlet Syndrome (TOS). We report our experience with, and technique for, robotic first rib resection. Methods: Patients diagnosed with TOS underwent robotic first rib resection of the offending portion of the first rib with disarticulation of the costo-sternal joint. Definitive diagnosis of TOS was made by Magnetic Resonance Angiography (MRA) with maneuvers. Results: A total of 67 patients underwent robotic first rib resection. Neurogenic TOS: 39 patients underwent robotic resection for Neurologic Symptoms of the upper extremity (Neurogenic TOS). There were 14 men and 25 women, with a mean age of 34 ± 9.5 years. Paget-Schroetter Syndrome (PSS) or Venous TOS: 28 patients underwent transthoracic robotic first rib resection for PSS. There were 16 men and 12 women, with a mean age of 24 ± 8.5 years. Operative time was 87.6 ± 10.8 minutes. There were no intraoperative complications. Hospital stay ranged from 2 to 4 days with a median hospitalization of 3 days. There were no neurovascular complications. There was no mortality. In patients with Neurogenic TOS, QuickDASH Scores (mean ± SEM) decreased from 60.3 ± 2.1 preoperatively to 5 ± 2.3 in the immediate postoperative period and to 3.5 ± 1.1 at 6 months (p<0001). Immediate relief of symptoms was seen in 35/39 patients (91%). Persistent paresthesia was seen in 4/39 (9%) immediately postop, and in 2/39 (2.5%) at 6 months. Thirty-seven of 39 (97.5%) patients reported complete relief of symptoms. Among patients with PSS or Venous TOS, 9/28 (32%) required endovascular venoplasty to completely open the subclavian vein after the relief of extrinsic compression. At a median follow-up of 24 months, all patients with PSS had an open subclavian vein, for a patency rate of 100%. Conclusions: Robotic transthoracic first rib resection allows for minimally invasive resection of the first rib in patients with TOS, with excellent relief of symptoms and no neurovascular complications.
MeSH term(s)	Adolescent ; Adult ; Female ; Humans ; Male ; Ribs ; Robotic Surgical Procedures ; Thoracic Outlet Syndrome/surgery ; Thoracic Surgical Procedures ; Treatment Outcome ; Young Adult
Keywords	covid19
Language	English
Publishing date	2020-01-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	1225512-9
ISSN	1090-3941
ISSN	1090-3941
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Article: Robotic first rib resection for thoracic outlet syndrome.

Gharagozloo, Farid / Atiquzzaman, Nabhan / Meyer, Mark / Tempesta, Barbara / Werden, Scott

Journal of thoracic disease

2021 Volume 13, Issue 10, Page(s) 6141–6154

Abstract: Robotic resection of the "offending portion" of the first rib in patients with thoracic outlet syndrome (TOS) has been associated with excellent results. The results have been due to (I) a better understanding of the pathogenesis of TOS, and (II) the ... ...

Abstract	Robotic resection of the "offending portion" of the first rib in patients with thoracic outlet syndrome (TOS) has been associated with excellent results. The results have been due to (I) a better understanding of the pathogenesis of TOS, and (II) the technical advantages of the robotic platform. This article outlines the recent understanding of the pathogenesis of TOS, and reports the experience with robotic resection of the "offending portion" of the first rib in patients with neurogenic and venous TOS. Patients diagnosed with TOS underwent robotic first rib resection. Diagnosis of TOS was made by magnetic resonance angiography (MRA). On a thoracoscopic platform, the robot was used to dissect the "offending portion" of the first rib. A total of 162 patients underwent robotic first rib resection. Eighty-three patients underwent robotic first rib resection for Paget-Schroetter syndrome (PSS) (venous TOS). There were 49 men and 34 women. Mean age was 24±8.5 years. Operative time was 127.6±20.8 minutes. Median hospitalization was 4 days. There were no surgical complications, neurovascular injuries, or mortality. At a median follow-up of 24 months, all patients had an open subclavian vein (SV) for a patency rate of 100%. Seventy-nine patients underwent robotic first rib resection for neurologic symptoms of the upper extremity (neurogenic TOS). There were 29 men and 50 women. Mean age was 34±9.5 years. Operative time was 87.6±10.8 minutes. There were no intraoperative complications. Hospital stay ranged from 2-4 days with a median hospitalization of 3 days. There were no neurovascular complications. There was no mortality. In patients with neurogenic symptoms, Quick DASH Scores (mean ± SEM) decreased from 60.3±2.1 preoperatively to 5±2.3 in the immediate postoperative period, and 3.5±1.1 at 6 months (P<0.0001). Immediate relief of symptoms was seen in 71/79 (91%) patients. Persistent paresthesia was seen in 9/79 (9%) immediately postop and 3/79 (3.8%) patients at 6 months. Following the appropriate identification of the "offending portion" of the first rib which results in compression of the SV at its junction with the innominate vein by MRA, robotic resection of the "offending portion" of the first rib allows is associated with excellent results.
Language	English
Publishing date	2021-11-18
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	2573571-8
ISSN	2077-6624 ; 2072-1439
ISSN (online)	2077-6624
ISSN	2072-1439
DOI	10.21037/jtd-2019-rts-04
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Article ; Online: The study of a hermaphroditic sheep caused by a mutation in the promoter of

Heidari, Farid / Rahbaran, Mohaddeseh / Mirzaei, Asieh / Mozafari Tabatabaei, Mehran / Shokrpoor, Sara / Mahjoubi, Frouzandeh / Ara, Mehdi Shams / Akbarinejad, Vahid / Gharagozloo, Faramarz

Veterinary and animal science

2023 Volume 21, Page(s) 100308

Abstract: In mammals, sex-determining region Y ( ...

Abstract	In mammals, sex-determining region Y (
Language	English
Publishing date	2023-07-24
Publishing country	Netherlands
Document type	Case Reports
ISSN	2451-943X
ISSN (online)	2451-943X
DOI	10.1016/j.vas.2023.100308
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Article ; Online: Author Correction: Evaluation of the relationship between vitamin D levels with oocyte quality in breast cancer women: a cross-sectional study.

Gharagozloo, Mahshid / Jahanian Sadatmahalleh, Shahideh / Kalhor, Mehri / Ghaffari, Firouzeh / Hasani, Fatemeh / Jahangiri, Nadia / Nasiri, Malihe / Khosravi, Ahmad

Scientific reports

2023 Volume 13, Issue 1, Page(s) 15042

Language	English
Publishing date	2023-09-12
Publishing country	England
Document type	Published Erratum
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-42122-0
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