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  1. Book ; Online: New Indicators for the Assessment and Prevention of Noise Nuisance

    Fredianelli, Luca / Lercher, Peter / Licitra, Gaetano

    2022  

    Keywords Technology: general issues ; History of engineering & technology ; sound emergence ; legislation ; annoyance ; measurement ; prediction ; uncertainty ; audibility ; signal-to-noise ratio ; sound pressure level ; field measurements ; spectrum analysis ; interior noise and vibration of vehicle ; COVID-19 ; noise ; soundscape ; metrics ; indicators ; descriptors ; sound ; lockdown ; Twitter ; geolocation ; noise classification ; seafarers ; acoustic pollution ; noise onboard ship ; health impact ; environmental pollution ; noise survey ; hypertension ; environmental noise ; railway noise ; recreational noise ; airport noise ; road traffic noise ; blood pressure ; noise annoyance ; diastolic blood pressure ; helicopter cabin ; noise levels ; noise reduction ; acoustic evaluation ; IAR Puma 330 ; ultrasound ; active noise control ; adjustable PAL ; quiet areas ; macro-temporal pattern ; noise indicator ; cognitive performance ; Stroop task ; listening experiment ; port noise ; noise sources ; noise mapping ; noise mitigations ; noise modeling ; ship noise ; sustainable management ; noise exposure prevention ; noise measurements ; research projects ; noise indicators ; noise metrics ; psychoacoustic ; nuisance ; sleep disturbance ; peak noise ; impulsive events ; health related quality of life ; health effects
    Language English
    Size 1 electronic resource (170 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English
    HBZ-ID HT030378782
    ISBN 9783036557403 ; 3036557407
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Next generation platinum salt in nasopharygeal carcinoma.

    Cavalieri, Stefano / Licitra, Lisa

    The Lancet. Oncology

    2021  Volume 22, Issue 5, Page(s) 577–578

    MeSH term(s) Carcinoma ; Chemoradiotherapy ; Cisplatin ; Cyclobutanes ; Fluorouracil ; Humans ; Induction Chemotherapy ; Nasopharyngeal Carcinoma/diagnosis ; Nasopharyngeal Carcinoma/drug therapy ; Nasopharyngeal Neoplasms ; Organoplatinum Compounds ; Platinum
    Chemical Substances Cyclobutanes ; Organoplatinum Compounds ; Platinum (49DFR088MY) ; lobaplatin (OX5XK1JD8C) ; Cisplatin (Q20Q21Q62J) ; Fluorouracil (U3P01618RT)
    Language English
    Publishing date 2021-04-12
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(21)00182-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5696: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 460: Show issues

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  3. Article: L-arginine reduces right heart hypertrophy in hypoxia-induced pulmonary hypertension.

    Fagan, J M / Rex, S E / Hayes-Licitra, S A / Waxman, L

    Biochemical and biophysical research communications

    1999  Volume 254, Issue 1, Page(s) 100–103

    Abstract: ... in rats exposed to 10 days of hypoxia (10% O2). Administration of l-arginine, the precursor for NO ...

    Abstract Endothelin (Et) and nitric oxide (NO) may serve as chemical mediators of hypoxia-induced pulmonary hypertension. Plasma levels of Et1 were elevated 2-fold while levels of nitrate, a NO metabolite, decreased in rats exposed to 10 days of hypoxia (10% O2). Administration of l-arginine, the precursor for NO, decreased Et, increased nitrate, and decreased right ventricular hypertrophy in hypoxic animals. By increasing plasma NO levels, the right ventricular hypertrophy and right heart failure seen in hypoxia-induced pulmonary hypertension in human patients may be prevented.
    MeSH term(s) Animals ; Arginine/administration & dosage ; Cardiomegaly/blood ; Cardiomegaly/drug therapy ; Cardiomegaly/physiopathology ; Endothelins/blood ; Heart Ventricles/drug effects ; Heart Ventricles/physiopathology ; Humans ; Hypertension, Pulmonary/blood ; Hypertension, Pulmonary/physiopathology ; Hypoxia ; Male ; Nitric Oxide/metabolism ; Rats ; Rats, Sprague-Dawley
    Chemical Substances Endothelins ; Nitric Oxide (31C4KY9ESH) ; Arginine (94ZLA3W45F)
    Language English
    Publishing date 1999-01-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 205723-2
    ISSN 0006-291X ; 0006-291X
    ISSN (online) 0006-291X
    ISSN 0006-291X
    DOI 10.1006/bbrc.1998.9887
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 116: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  4. Article ; Online: An Old but Still Unanswered Question in Recurrent or Metastatic Salivary Duct Carcinoma.

    Cavalieri, Stefano / Locati, Laura Deborah / Licitra, Lisa

    JCO precision oncology

    2022  Volume 5, Page(s) 1526–1527

    MeSH term(s) Carcinoma, Ductal/pathology ; Humans ; Salivary Ducts/pathology ; Salivary Gland Neoplasms/therapy
    Language English
    Publishing date 2022-01-07
    Publishing country United States
    Document type Letter ; Comment
    ISSN 2473-4284
    ISSN (online) 2473-4284
    DOI 10.1200/PO.21.00262
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: New Indicators for the Assessment and Prevention of Noise Nuisance.

    Fredianelli, Luca / Lercher, Peter / Licitra, Gaetano

    International journal of environmental research and public health

    2022  Volume 19, Issue 19

    Abstract: At present, health effects induced by prolonged noise exposure are widely studied to determine the most spread noise sources and their effects [ ... ]. ...

    Abstract At present, health effects induced by prolonged noise exposure are widely studied to determine the most spread noise sources and their effects [...].
    MeSH term(s) Environmental Exposure/prevention & control ; Noise
    Language English
    Publishing date 2022-10-05
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph191912724
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Statistical Pass-By for Unattended Road Traffic Noise Measurement in an Urban Environment.

    Ascari, Elena / Cerchiai, Mauro / Fredianelli, Luca / Licitra, Gaetano

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 22

    Abstract: Low-noise surfaces have become a common mitigation action in the last decade, so much so that different methods for feature extraction have been established to evaluate their efficacy. Among these, the Close Proximity Index (CPX) evaluates the noise ... ...

    Abstract Low-noise surfaces have become a common mitigation action in the last decade, so much so that different methods for feature extraction have been established to evaluate their efficacy. Among these, the Close Proximity Index (CPX) evaluates the noise emissions by means of multiple runs at different speeds performed with a vehicle equipped with a reference tire and with acoustic sensors close to the wheel. However, signals acquired with CPX make it source oriented, and the analysis does not consider the real traffic flow of the studied site for a receiver-oriented approach. These aspects are remedied by Statistical Pass-By (SPB), a method based on sensor feature extraction with live detection of events; noise and speed acquisitions are performed at the roadside in real case scenarios. Unfortunately, the specific SPB requirements for its measurement setup do not allow an evaluation in urban context unless a special setup is used, but this may alter the acoustical context in which the measurement was performed. The present paper illustrates the testing and validation of a method named Urban Pass-By (U-SPB), developed during the LIFE NEREiDE project. U-SPB originates from standard SPB, exploits unattended measurements and develops an in-lab feature detection and extraction procedure. The U-SPB extends the evaluation in terms of before/after data comparison of the efficiency of low-noise laying in an urban context while combining the estimation of long-term noise levels and traffic parameters for other environmental noise purposes, such as noise mapping and action planning.
    MeSH term(s) Noise, Transportation ; Acoustics
    Language English
    Publishing date 2022-11-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22228767
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Oligometastatic disease from differentiated thyroid cancer: best treatment schemes.

    Colombo, Elena / Ottini, Arianna / Licitra, Lisa

    Current opinion in oncology

    2022  Volume 35, Issue 1, Page(s) 15–21

    Abstract: Purpose of review: Patients with slowly progressive and/or symptomatic oligometastatic radioactive iodine refractory (RAIR) differentiated thyroid carcinomas (DTCs) are candidates to receive locoregional treatment to delay the start of systemic therapy ... ...

    Abstract Purpose of review: Patients with slowly progressive and/or symptomatic oligometastatic radioactive iodine refractory (RAIR) differentiated thyroid carcinomas (DTCs) are candidates to receive locoregional treatment to delay the start of systemic therapy with multikinase inhibitors. Information provided by the recent literature has not been extensively reviewed in previous published works, thus we aim to bridge this gap.
    Recent findings: We present for each metastatic site the different locoregional treatment options, contraindications and potential adverse events. Some techniques can be combined together, whereas others are discouraged in certain situations, requiring a high level of expertise and multidisciplinarity in the treatment algorithm.
    Summary: Different techniques of radiation therapy and interventional radiology allow to control the metastatic spread. However, as no clinical trials are available to compare the treatment schemes in terms of safety and potential impact on the prognosis, the most appropriate option for each patient should be selected within a multidisciplinary decision making, taking into account the clinical conditions and the pattern/rapidity of metastatic disease.
    MeSH term(s) Humans ; Thyroid Neoplasms/therapy ; Iodine Radioisotopes/therapeutic use
    Chemical Substances Iodine Radioisotopes
    Language English
    Publishing date 2022-11-21
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1049384-0
    ISSN 1531-703X ; 1040-8746
    ISSN (online) 1531-703X
    ISSN 1040-8746
    DOI 10.1097/CCO.0000000000000921
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3046: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  8. Article ; Online: Which future for de-intensified treatments in HPV-related oropharyngeal carcinoma?

    Cavalieri, Stefano / Nuzzolese, Imperia / Licitra, Lisa

    Seminars in oncology

    2022  Volume 49, Issue 5, Page(s) 405–408

    Abstract: The development of deintensified therapies aiming at reducing the treatment-related toxicity while not impairing the outcome is an unmet need in HPV+ oropharyngeal carcinoma patients. Several deintensification approaches have been explored in this ... ...

    Abstract The development of deintensified therapies aiming at reducing the treatment-related toxicity while not impairing the outcome is an unmet need in HPV+ oropharyngeal carcinoma patients. Several deintensification approaches have been explored in this setting, including induction chemotherapy with reduced chemoradiation dose in responding pts. The findings of the studies conducted so far show that the available deescalated therapy should be based on the disease risk profile. At present, we still lack robust high level data to infer that the cited interventions are equivalent or superior to standard of care treatments. However, literature data suggest that approximately 70% of low-risk patients might receive a deintensified approach by including either surgery or induction chemotherapy. In the context of high-risk disease, more than 80% of patients may undergo a deintensified loco-regional treatment by neoadjuvant systemic therapy. Epidemiological data suggest that in the next decades, most of the HPV-related OPSCC patients will be made of old and possibly frail individuals. However, this patient population was excluded from most of the studies conducted so far. Therefore, there is a strong need for clinical trials to define risk-based deescalation strategies in this population and in younger patients as well.
    MeSH term(s) Humans ; Papillomavirus Infections/complications ; Papillomavirus Infections/therapy ; Oropharyngeal Neoplasms/pathology ; Oropharyngeal Neoplasms/surgery ; Chemoradiotherapy ; Combined Modality Therapy ; Carcinoma
    Language English
    Publishing date 2022-09-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 189220-4
    ISSN 1532-8708 ; 0093-7754
    ISSN (online) 1532-8708
    ISSN 0093-7754
    DOI 10.1053/j.seminoncol.2022.09.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1348: Show issues Location:
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  9. Article ; Online: 'Rare cancers': not all together in clinical studies!

    Casali, P G / Licitra, L / Frezza, A M / Trama, A

    Annals of oncology : official journal of the European Society for Medical Oncology

    2022  Volume 33, Issue 5, Page(s) 463–465

    MeSH term(s) Humans ; Neoplasms/therapy ; Rare Diseases
    Language English
    Publishing date 2022-02-04
    Publishing country England
    Document type Editorial
    ZDB-ID 1025984-3
    ISSN 1569-8041 ; 0923-7534
    ISSN (online) 1569-8041
    ISSN 0923-7534
    DOI 10.1016/j.annonc.2022.01.077
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2862: Show issues Location:
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  10. Article ; Online: Induction chemotherapy is the best timekeeper in nasopharyngeal carcinoma.

    Cavalieri, Stefano / Licitra, Lisa

    Cancer

    2020  Volume 126, Issue 16, Page(s) 3624–3626

    MeSH term(s) Epstein-Barr Virus Infections/drug therapy ; Epstein-Barr Virus Infections/epidemiology ; Epstein-Barr Virus Infections/virology ; Herpesvirus 4, Human/pathogenicity ; Humans ; Induction Chemotherapy ; Nasopharyngeal Carcinoma/drug therapy ; Nasopharyngeal Carcinoma/epidemiology ; Nasopharyngeal Carcinoma/virology ; Nasopharyngeal Neoplasms/drug therapy ; Nasopharyngeal Neoplasms/epidemiology ; Nasopharyngeal Neoplasms/virology
    Language English
    Publishing date 2020-06-04
    Publishing country United States
    Document type Editorial
    ZDB-ID 1429-1
    ISSN 1097-0142 ; 0008-543X ; 1934-662X
    ISSN (online) 1097-0142
    ISSN 0008-543X ; 1934-662X
    DOI 10.1002/cncr.32971
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh III Zs.146: Show issues Location:
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