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  1. Article ; Online: Study of toe deformities in diabetic foot through Amit Jains extended SCC classification

    Amit Kumar C Jain / Apoorva HC

    Medicine Science, Vol 9, Iss 4, Pp 982-

    2020  Volume 7

    Abstract: ... with diabetes through the new Amit Jains extended SCC classification. A total of 27 patients were included ...

    Abstract A study was conducted to analyze the visible named toe deformities that occur in foot of patients with diabetes through the new Amit Jains extended SCC classification. A total of 27 patients were included who fulfilled the criteria. Majority of the patients (59.3%) were males. 11.1% of patients had diabetes of more than 24 years duration. Type 1 toe deformities were the most common deformities seen in 85.2% of the cases. Hammer toe was the commonest pathological type followed by claw toes. Around 14.8% had underlying callus/ulcers (complex deformity). This new classification is simple and easy to use in clinical practice. [Med-Science 2020; 9(4.000): 982-7]
    Keywords diabetes ; foot ; toes ; ulcer ; amit jain ; deformity ; Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2020-12-01T00:00:00Z
    Publisher Society of TURAZ AKADEMI
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Pilot testing the new Amit Jains scoring system for diabetic foot ulcer in predicting the risk of amputation

    Amit Kumar C Jain / Apoorva HC / Kishore Kumar G

    Medicine Science, Vol 10, Iss 3, Pp 741-

    2021  Volume 5

    Abstract: The aim of this study was to test the new Amit Jains diabetic foot ulcer scoring and determine ... ulcer. The mean Amit Jains scoring (AJ Scoring) was 5.31±1.37. Majority of the patients were in moderate ... risk category. 33.33% had amputation. Significant association (P=0.02) was noted with Amit Jains ...

    Abstract The aim of this study was to test the new Amit Jains diabetic foot ulcer scoring and determine the predictive validity of this simple scoring for amputation in diabetic foot ulcers. This newly derived score was applied to the above authors study that was previously done on 54 patients with diabetic foot ulcer. The mean Amit Jains scoring (AJ Scoring) was 5.31±1.37. Majority of the patients were in moderate risk category. 33.33% had amputation. Significant association (P=0.02) was noted with Amit Jains increasing score and amputation. Patients who had major amputation were in high-risk category group (P=0.006). The odds ratio for major amputation category was 3.39. This newly derived Amit Jains diabetic foot ulcer score is simple, easy to remember score that is an excellent predictor of amputation. Further studies are needed to know its predictive ability for healing of the ulcer. [Med-Science 2021; 10(3.000): 741-5]
    Keywords diabetic foot ; ulcer ; amit jains ; scoring ; classification ; amputation ; Medicine ; R ; Medicine (General) ; R5-920
    Subject code 616
    Language English
    Publishing date 2021-09-01T00:00:00Z
    Publisher Society of TURAZ AKADEMI
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: To evaluate transmetatarsal amputation in diabetic foot through the Amit Jains system of practice An experience from 2 different centres

    Amit Kumar C Jain / Apoorva HC / Rajagopalan S

    Medicine Science, Vol 9, Iss 4, Pp 888-

    2020  Volume 95

    Abstract: ... through Amit Jains universal classification and scoring system and assess major amputations done ... in them. We conducted a descriptive retrospective analysis from 2 centers namely Amit Jains Institute of Diabetic Foot ...

    Abstract The aim of this study was to evaluate trans metatarsal amputation (TMA) done in diabetic foot through Amit Jains universal classification and scoring system and assess major amputations done in them. We conducted a descriptive retrospective analysis from 2 centers namely Amit Jains Institute of Diabetic Foot &Wound Care at Brindhavvan Areion Hospital and at Department of surgery, Raja Rajeswari medical college, Bengaluru, India. The study period was from January 2017 to June 2018. 15 patients were recruited in the study with 73.3% of them being males. Around 20 % of them were above 70 years of age. Majority of patients who underwent TMA had open stump and it had significant association with duration of diabetes. Specialist diabetic foot surgeon had significant propensity to close the stump after trans metatarsal amputation (P [Med-Science 2020; 9(4.000): 888-95]
    Keywords diabetic foot ; amputation ; abscess ; wet gangrene ; ulcer ; Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2020-12-01T00:00:00Z
    Publisher Society of TURAZ AKADEMI
    Document type Article ; Online
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  4. Article ; Online: Auditing the usage of therapeutic footwear in diabetic foot patients through Amit Jains extended SCC classification for therapeutic footwear

    Amit Kumar C Jain / Apoorva HC

    Medicine Science, Vol 9, Iss 2, Pp 437-

    2020  Volume 42

    Abstract: ... in diabetic foot patients through the new Amit Jains classification for therapeutic footwear. Twenty seven new ... years without changing them. Amit Jains classification for therapeutic footwear is a new, simple ...

    Abstract An audit was conducted from 2 centres to analyze and study the therapeutic footwear used in diabetic foot patients through the new Amit Jains classification for therapeutic footwear. Twenty seven new patients who were on therapeutic foot wear were studied. The majority were males. Most of the patients had diabetes duration of more than 20 years (48.7%). Most of the patients were on diabetic sandals (81.5%) followed by modified molded (Custom) footwear (7.4%). Majority of the Footwear used were type 1 diabetic footwear (81.5%). There was a significance difference seen with type of footwear and duration of footwear usage with age wherein type 1 therapeutic footwear were used commonly in patients with age less than and also in patients with more than 60 years whereas type 3 foot wear was used only by patients of less than 60 years. Further, patients above 60 years duration were using therapeutic footwear for more than 2 years without changing them. Amit Jains classification for therapeutic footwear is a new, simple, practical, easy to remember classification for diabetic foot wear wherein all footwears can easily be categorized in any one of the 3 categorizes and it helps in our understanding of diabetic footwear usage. [Med-Science 2020; 9(2.000): 437-42]
    Keywords diabetes ; foot ; amit jain ; classification ; footwear ; sandals ; Medicine ; R ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher Society of TURAZ AKADEMI
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Locally Advanced Breast Cancer: Response Evaluation to Neoadjuvant Chemotherapy by Clinico-Histopathological Parameters and Molecular Imaging.

    Jain, Amit Kumar

    Indian journal of surgical oncology

    2023  Volume 14, Issue 2, Page(s) 279–287

    Abstract: In India, breast cancer (BC) is not only the commonest cancer but also the commonest cause of cancer mortality among females. Advanced BC constitutes >70% of BC cases at initial presentation in India, among which locally advanced breast cancer (LABC) ... ...

    Abstract In India, breast cancer (BC) is not only the commonest cancer but also the commonest cause of cancer mortality among females. Advanced BC constitutes >70% of BC cases at initial presentation in India, among which locally advanced breast cancer (LABC) requires a multi-disciplinary approach with a combination of systemic and locoregional therapies. This descriptive hospital-based study was conducted over 1½ years after seeking approval from the institutional ethics committee. Fifty-five patients satisfying all the criteria of the study were enrolled. The data, thus, collected was pooled into Excel spreadsheet and analyzed using appropriate statistical tools. Most of the patients were postmenopausal, multiparous with breast lump being the commonest symptom. Mean baseline characteristics were age - 48 years, SUV max - 9.2, and Ki-67 - 17.8%. cT4 and cN2 were the commonest pre-NACT tumor and lymph node stage. Invasive ductal carcinoma was the commonest tumor type with the most common tumor grade being grade 3. Hormone receptor positivity and HER2 overexpression were seen in 33 and 17 patients respectively. Post-NACT 32 patients underwent breast-conserving surgery. Pathological complete response (pCR), i.e., ypT0N0, was seen in 13 patients (23.6%). There was slight alteration in hormone receptor status, HER2 expression and Ki-67 in the post-NACT resected tumor. pCR, which is a surrogate marker for improved clinical outcome (DFS and OS) in LABC patients, occurred more commonly in patients with pre-NACT grade 3 tumors, high Ki-67, hormone receptor-negative, and HER2 overexpressing BC (overall, in triple negative BC) but was statistically significant only with Ki-67. Post-NACT, SUV max with a cut off ≤1.5, and ΔSUV max of >80% correlated closely with pCR.
    Language English
    Publishing date 2023-02-06
    Publishing country India
    Document type Journal Article
    ZDB-ID 2568289-1
    ISSN 0976-6952 ; 0975-7651
    ISSN (online) 0976-6952
    ISSN 0975-7651
    DOI 10.1007/s13193-023-01711-1
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  6. Article ; Online: Gaining New Heights in Adult Deformity Surgery: Commentary on an article by Bassel G. Diebo, MD, et al.: "Height Gain Following Correction of Adult Spinal Deformity".

    Jain, Deeptee / Jain, Amit

    The Journal of bone and joint surgery. American volume

    2023  Volume 105, Issue 18, Page(s) e45

    MeSH term(s) Adult ; Humans ; Body Height ; Spine/surgery
    Language English
    Publishing date 2023-09-20
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 220625-0
    ISSN 1535-1386 ; 0021-9355
    ISSN (online) 1535-1386
    ISSN 0021-9355
    DOI 10.2106/JBJS.23.00710
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  7. Article ; Online: Olfactory Nasal Nitric Oxide Link in COVID-19: A Marker of Neurogenesis or Risk Factor for Chronic Rhinosinusitis?

    Jain, Amit

    American journal of respiratory and critical care medicine

    2021  Volume 204, Issue 11, Page(s) 1345–1347

    MeSH term(s) COVID-19 ; Humans ; Neurogenesis ; Nitric Oxide ; Rhinitis ; Risk Factors ; SARS-CoV-2
    Chemical Substances Nitric Oxide (31C4KY9ESH)
    Language English
    Publishing date 2021-09-07
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202107-1697LE
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  8. Article ; Online: Deregulated kynurenine metabolism - An alternate hypothesis for COVID-19 associated anosmia.

    Jain, Amit

    Medical hypotheses

    2021  Volume 157, Page(s) 110721

    MeSH term(s) Anosmia ; COVID-19 ; Humans ; Indoleamine-Pyrrole 2,3,-Dioxygenase ; Kynurenine ; SARS-CoV-2 ; Tryptophan
    Chemical Substances Indoleamine-Pyrrole 2,3,-Dioxygenase ; Kynurenine (343-65-7) ; Tryptophan (8DUH1N11BX)
    Language English
    Publishing date 2021-10-29
    Publishing country United States
    Document type Letter
    ZDB-ID 193145-3
    ISSN 1532-2777 ; 0306-9877
    ISSN (online) 1532-2777
    ISSN 0306-9877
    DOI 10.1016/j.mehy.2021.110721
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  9. Article ; Online: High Circulating Plasma Soluble Receptor for Advanced Glycation End-Products in Early COVID-19-associated Acute Respiratory Distress Syndrome: Pathophysiological Significance?

    Jain, Amit

    American journal of respiratory and critical care medicine

    2021  Volume 205, Issue 2, Page(s) 254–256

    MeSH term(s) COVID-19 ; Glycation End Products, Advanced ; Humans ; Receptor for Advanced Glycation End Products ; Respiratory Distress Syndrome ; SARS-CoV-2
    Chemical Substances Glycation End Products, Advanced ; Receptor for Advanced Glycation End Products
    Language English
    Publishing date 2021-11-02
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202108-1896LE
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  10. Article ; Online: Computational identification of candidate inhibitors for Dihydrofolate reductase in

    Bhati, Saurabh Kumar / Jain, Monika / Muthukumaran, Jayaraman / Singh, Amit Kumar

    Current research in structural biology

    2024  Volume 7, Page(s) 100127

    Abstract: Acinetobacter ... ...

    Abstract Acinetobacter baumannii
    Language English
    Publishing date 2024-01-17
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2665-928X
    ISSN (online) 2665-928X
    DOI 10.1016/j.crstbi.2024.100127
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