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Article: Staging of lung cancer.

Milroy, Robert

2008 Volume 133, Issue 3, Page(s) 593–595

MeSH term(s)	Biopsy, Needle ; Bronchoscopy/methods ; Carcinoma, Non-Small-Cell Lung/epidemiology ; Carcinoma, Non-Small-Cell Lung/pathology ; Global Health ; Humans ; Lung Neoplasms/epidemiology ; Lung Neoplasms/pathology ; Morbidity/trends ; Neoplasm Staging/methods ; Retrospective Studies ; Severity of Illness Index ; Tomography, Emission-Computed, Single-Photon/methods ; Tomography, X-Ray Computed/methods
Language	English
Publishing date	2008-03
Publishing country	United States
Document type	Comment ; Editorial
ZDB-ID	1032552-9
ISSN	1931-3543 ; 0012-3692
ISSN (online)	1931-3543
ISSN	0012-3692
DOI	10.1378/chest.07-2638
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Article: New American College of Chest Physicians lung cancer guidelines: an important addition to the lung cancer guidelines armamentarium.

Milroy, Robert

Chest

2007 Volume 132, Issue 3, Page(s) 744–746

MeSH term(s)	Humans ; Lung Neoplasms/diagnosis ; Lung Neoplasms/epidemiology ; Lung Neoplasms/therapy ; Practice Guidelines as Topic
Language	English
Publishing date	2007-09
Publishing country	United States
Document type	Editorial
ZDB-ID	1032552-9
ISSN	1931-3543 ; 0012-3692
ISSN (online)	1931-3543
ISSN	0012-3692
DOI	10.1378/chest.07-1493
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Article ; Online: Lung cancer stigma: A concept with consequences for patients.

Maguire, Roma / Lewis, Liane / Kotronoulas, Grigorios / McPhelim, John / Milroy, Robert / Cataldo, Janine

Cancer reports (Hoboken, N.J.)

2019 Volume 2, Issue 5, Page(s) e1201

Abstract: Background: Patients with lung cancer (LC) report lower quality of life (QoL) and higher levels of psychological distress compared with other cancer populations. Lung cancer stigma (LCS) may in part explain these findings.: Aim: We investigated the ... ...

Abstract	Background: Patients with lung cancer (LC) report lower quality of life (QoL) and higher levels of psychological distress compared with other cancer populations. Lung cancer stigma (LCS) may in part explain these findings. Aim: We investigated the prevalence of patient-perceived lung cancer stigma (LCS) and its relationships to symptom burden/severity, depression, and deficits in health-related quality of life (HR-QoL). Methods: In this descriptive, observational, and cross-sectional study, 201 participants were sent questionnaires. These included the Cataldo Lung Cancer Stigma Scale (CLCSS), the Lung Cancer Symptom Scale, the Centre for Epidemiologic Studies-Depression Scale, and the Quality of Life Inventory. Results: Participants were on average 69 years old, 52% women, 95% ever smokers, and 18.5% current smokers. The mean total CLCSS score was 53.1 (SD = 14.1; range = 31-94). LCS was significantly correlated with younger age (P < .001), greater social deprivation (P < .05), being unemployed (P < .001), depression (P < .001), symptom burden (P < .001), and HR-QoL deficits (P < .001). Symptom burden explained 18% of variance in LCS (P < .001). LCS explained 8.5% and 14.3% of the variance in depression (P < .001) and HR-QoL (P < .001), respectively. Conclusion: Patients with lung cancer are vulnerable to LCS. Symptom burden can directly contribute to greater perceived LCS. Greater perceived LCS can be directly related to greater levels of depression and lower HR-QoL. A tailored approach is required to screen for LCS and implement interventions to enhance the psychosocial well-being of patients with perceived LCS.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Cancer Survivors/psychology ; Cross-Sectional Studies ; Depression/diagnosis ; Depression/epidemiology ; Depression/etiology ; Depression/psychology ; Female ; Humans ; Lung Neoplasms/diagnosis ; Lung Neoplasms/psychology ; Male ; Middle Aged ; Psychiatric Status Rating Scales/statistics & numerical data ; Psychological Distress ; Quality of Life ; Scotland ; Severity of Illness Index ; Social Stigma ; Survivorship
Language	English
Publishing date	2019-06-24
Publishing country	United States
Document type	Journal Article ; Multicenter Study ; Observational Study ; Research Support, Non-U.S. Gov't
ISSN	2573-8348
ISSN (online)	2573-8348
DOI	10.1002/cnr2.1201
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Article: Chronic obstructive pulmonary disease: a complex comorbidity of lung cancer.

Grose, Derek / Milroy, Robert

Journal of comorbidity

2011 Volume 1, Page(s) 45–50

Abstract: Chronic obstructive pulmonary disease (COPD) is a major burden throughout the world. It is associated with a significantly increased incidence of lung cancer and may influence treatment options and outcome. Impaired lung function confirming COPD is an ... ...

Abstract	Chronic obstructive pulmonary disease (COPD) is a major burden throughout the world. It is associated with a significantly increased incidence of lung cancer and may influence treatment options and outcome. Impaired lung function confirming COPD is an independent risk factor for lung cancer. Oxidative stress and inflammation may be a key link between COPD and lung cancer, with numerous molecular markers being analysed to attempt to understand the pathway of lung cancer development. COPD negatively influences the ability to deliver radical treatment options, so attempts must be made to look for alternative methods of treating lung cancer, while aiming to manage the underlying COPD. Detailed assessment and management plans utilising the multidisciplinary team must be made for all lung cancer patients with COPD to provide the best care possible. Journal of Comorbidity 2011;1:45-50.
Language	English
Publishing date	2011-12-27
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2831678-2
ISSN	2235-042X ; 2235-042X
ISSN (online)	2235-042X
ISSN	2235-042X
DOI	10.15256/joc.2011.1.5
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Article ; Online: Obtaining tissue diagnosis in lung cancer patients with poor performance status and its influence on treatment and survival.

Maclay, John D / Farley, John M B / McCowan, Colin / Tweed, Conor / Milroy, Robert

Respiratory medicine

2017 Volume 124, Page(s) 30–35

Abstract: Introduction: 25% of patients with lung cancer have performance status 3 or 4. A pragmatic approach to investigative procedures is often adopted based on the risks and benefits in these patients and whether tissue diagnosis is necessary for anticipated ... ...

Abstract	Introduction: 25% of patients with lung cancer have performance status 3 or 4. A pragmatic approach to investigative procedures is often adopted based on the risks and benefits in these patients and whether tissue diagnosis is necessary for anticipated future treatment. This cohort study investigated factors influencing a clinician's decision to pursue a tissue diagnosis in patients with lung cancer and performance status 3 and 4 and to examine the association of tissue diagnosis with subsequent management and survival. Methods: All patients with lung cancer diagnosed in North Glasgow from 2009 to 2012 were prospectively recorded in a registry. We investigated the relationships between achieving a tissue diagnosis, treatment and survival. Results: Of 2493 patients diagnosed with lung cancer, 490 patients (20%) were PS 3 and 122 patients (5%) were PS 4. Tissue diagnosis was attempted in 60% and 35% patients with PS 3 and PS 4 respectively. Younger age, better performance status and having stage 4 disease were independently associated with a diagnostic procedure being performed. Only 5% of patients with poor performance status received treatment conventionally requiring a tissue diagnosis. Age, stage and performance status were independent predictors of mortality. Achieving a tissue diagnosis was not associated with mortality. Receiving treatment requiring tissue diagnosis is associated with survival benefit. Conclusions: The majority of patients with poor fitness undergo a diagnostic procedure which does not influence further treatment or affect survival. However, the cohort of patients who do undergo therapy determined by tissue diagnosis have improved survival.
Language	English
Publishing date	2017-03
Publishing country	England
Document type	Journal Article
ZDB-ID	1003348-8
ISSN	1532-3064 ; 0954-6111
ISSN (online)	1532-3064
ISSN	0954-6111
DOI	10.1016/j.rmed.2017.01.002
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Article ; Online: ADVANCE-1: An adapted collaborative benchmarking approach in centre-based lung cancer care.

McCann, Brendan / Muhr, Riccardo / O'Rourke, Noelle / Milroy, Robert / Kollmeier, Jens / Misch, Daniel / van der Horst, Joris / Morrison, David / Bauer, Torsten / Massalski, Oliver / Blum, Torsten Gerriet

Lung cancer (Amsterdam, Netherlands)

2020 Volume 151, Page(s) 44–52

Abstract: The majority of research within lung cancer is focused on prevention, diagnosis and treatment rather than examining infrastructure or processes of lung cancer centres. Benchmarking is a systematic method for documenting and comparing processes, functions ...

Abstract	The majority of research within lung cancer is focused on prevention, diagnosis and treatment rather than examining infrastructure or processes of lung cancer centres. Benchmarking is a systematic method for documenting and comparing processes, functions or performance of organisations against the best in the world. ADVANCE-1 is a European Respiratory Society funded pilot study with the main aim of creating a benchmarking tool that can easily document and reflect the structure and process within a lung cancer centre and its associated registry. By doing this we can then compare centres and generate best practice learning points from each centre in order to learn from each other. The ADVANCE-1 study group was constituted by two ERS fellowship-holders and senior lung cancer specialists from the two participating lung cancer services in Glasgow, Scotland, and Berlin, Germany. The study design and benchmarking tools were reviewed externally. Once the benchmarking tools were created, prospective testing was undertaken in the two participating centres in order to allow comparison to ascertain best practice in a so called 'collaborative benchmarking approach'. We were then able to create personalised learning points for each centre. The next phase of the project will be to expand the benchmarking across several European centres in the ADANCE-2 project.
MeSH term(s)	Benchmarking ; Germany ; Humans ; Lung Neoplasms/diagnosis ; Lung Neoplasms/epidemiology ; Lung Neoplasms/therapy ; Pilot Projects ; Prospective Studies ; Scotland
Language	English
Publishing date	2020-11-26
Publishing country	Ireland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	632771-0
ISSN	1872-8332 ; 0169-5002
ISSN (online)	1872-8332
ISSN	0169-5002
DOI	10.1016/j.lungcan.2020.11.019
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Article ; Online: European Respiratory Society guideline on various aspects of quality in lung cancer care.

Blum, Torsten Gerriet / Morgan, Rebecca L / Durieux, Valérie / Chorostowska-Wynimko, Joanna / Baldwin, David R / Boyd, Jeanette / Faivre-Finn, Corinne / Galateau-Salle, Françoise / Gamarra, Fernando / Grigoriu, Bogdan / Hardavella, Georgia / Hauptmann, Michael / Jakobsen, Erik / Jovanovic, Dragana / Knaut, Paul / Massard, Gilbert / McPhelim, John / Meert, Anne-Pascale / Milroy, Robert /

Muhr, Riccardo / Mutti, Luciano / Paesmans, Marianne / Powell, Pippa / Putora, Paul Martin / Rawlinson, Janette / Rich, Anna L / Rigau, David / de Ruysscher, Dirk / Sculier, Jean-Paul / Schepereel, Arnaud / Subotic, Dragan / Van Schil, Paul / Tonia, Thomy / Williams, Clare / Berghmans, Thierry

The European respiratory journal

2023 Volume 61, Issue 2

Abstract: This European Respiratory Society guideline is dedicated to the provision of good quality recommendations in lung cancer care. All the clinical recommendations contained were based on a comprehensive systematic review and evidence syntheses based on ... ...

Abstract	This European Respiratory Society guideline is dedicated to the provision of good quality recommendations in lung cancer care. All the clinical recommendations contained were based on a comprehensive systematic review and evidence syntheses based on eight PICO (Patients, Intervention, Comparison, Outcomes) questions. The evidence was appraised in compliance with the GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach. Evidence profiles and the GRADE Evidence to Decision frameworks were used to summarise results and to make the decision-making process transparent. A multidisciplinary Task Force panel of lung cancer experts formulated and consented the clinical recommendations following thorough discussions of the systematic review results. In particular, we have made recommendations relating to the following quality improvement measures deemed applicable to routine lung cancer care: 1) avoidance of delay in the diagnostic and therapeutic period, 2) integration of multidisciplinary teams and multidisciplinary consultations, 3) implementation of and adherence to lung cancer guidelines, 4) benefit of higher institutional/individual volume and advanced specialisation in lung cancer surgery and other procedures, 5) need for pathological confirmation of lesions in patients with pulmonary lesions and suspected lung cancer, and histological subtyping and molecular characterisation for actionable targets or response to treatment of confirmed lung cancers, 6) added value of early integration of palliative care teams or specialists, 7) advantage of integrating specific quality improvement measures, and 8) benefit of using patient decision tools. These recommendations should be reconsidered and updated, as appropriate, as new evidence becomes available.
MeSH term(s)	Humans ; Lung/pathology ; Lung Neoplasms/diagnosis ; Lung Neoplasms/therapy ; Lung Neoplasms/pathology ; Thorax ; Societies, Medical
Language	English
Publishing date	2023-02-16
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	639359-7
ISSN	1399-3003 ; 0903-1936
ISSN (online)	1399-3003
ISSN	0903-1936
DOI	10.1183/13993003.03201-2021
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Article: Fighting lung cancer in the developed world--a model of care in a UK hospital.

Baig, Inam Mohammad / Downer, Penny / Milroy, Robert

JPMA. The Journal of the Pakistan Medical Association

2010 Volume 60, Issue 2, Page(s) 93–97

Abstract: Objectives: To highlight the initial management approach for Lung Cancer in a UK Hospital with the aim of translating the principles of such methodology to a developing country, such as Pakistan.: Methods: A descriptive observational study was ... ...

Abstract	Objectives: To highlight the initial management approach for Lung Cancer in a UK Hospital with the aim of translating the principles of such methodology to a developing country, such as Pakistan. Methods: A descriptive observational study was carried out at Stobhill Hospital, Glasgow, UK. The investigator (IMB) observed the Lung Cancer Service, attending the weekly 'New patients Clinic', 'Results Clinic', and 'Multidisciplinary team (MDT) meetings'. The process observations and the factual data describing the details of the service were recorded on a pre-designed pro-forma. Observations relating to two aspects of this service (Results Clinic and MDT) are included in this report. Results: The methodology of communicating results of lung cancer investigations to patients in a pre-planned and staged manner at a dedicated 'Results Clinic' was identified as a useful approach. A format of communication was consistently followed. Conclusion: The MDT consisted of a Respiratory Physician, Clinical Oncologist, Thoracic Surgeon, Radiologist, Pathologist and Palliative Care Specialist. Each patient's case was discussed on an individual basis and the team developed a consensus regarding diagnosis, staging of the disease, further need for diagnostic procedures and treatment options, bearing in mind the patient's performance status, co-morbidity and their wishes. This approach has improved the initial part of the lung cancer patient journey and components of this approach could easily be transferred to a developing country.
MeSH term(s)	Clinical Protocols ; Humans ; Lung Neoplasms/diagnosis ; Lung Neoplasms/therapy ; Prospective Studies ; United Kingdom
Language	English
Publishing date	2010-02
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	603873-6
ISSN	0030-9982
ISSN	0030-9982
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Article ; Online: Exploring Inclusion of College Students with IDD in Campus Recreation and Sports Through the Lens of IPSE Programs’ Organizational Level Stakeholders

Lindsey Ryan Oakes / Tracy R. Nichols, Ph.D. / Stuart J. Schleien, Ph.D., LRT/CTRS, CPRP / Jeffrey J. Milroy, Dr.PH / Robert W. Strack, Ph.D.

Journal of Inclusive Postsecondary Education, Vol 2, Iss

2020 Volume 2

Abstract: Participation in recreation and sports can produce health benefits for all college students and open pathways to inclusion for individuals with intellectual and/or developmental disabilities (IDD). Despite the growing number of college students with IDD ... ...

Abstract	Participation in recreation and sports can produce health benefits for all college students and open pathways to inclusion for individuals with intellectual and/or developmental disabilities (IDD). Despite the growing number of college students with IDD on over 260 college campuses across the United States, there is a dearth of literature exploring their inclusion within campus recreation and sports. This study examined how organizational culture of campus recreation and sports departments and inclusive postsecondary education (IPSE) programs support and inhibit inclusion of college students with IDD, along with placements of IPSE programs on an academic-specific and broader continuum of inclusion.
Keywords	inclusion ; campus recreation and sports ; intellectual and/or developmental disability ; organizational culture ; inclusive postsecondary education programs ; Special aspects of education ; LC8-6691
Subject code	796
Language	English
Publishing date	2020-09-01T00:00:00Z
Publisher	Mason Journals
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Chronic Obstructive Pulmonary Disease

Derek Grose MRCP, FRCR / Robert Milroy

Journal of Comorbidity, Vol

A Complex Comorbidity of Lung Cancer

2011 Volume 1

Abstract	Chronic obstructive pulmonary disease (COPD) is a major burden throughout the world. It is associated with a significantly increased incidence of lung cancer and may influence treatment options and outcome. Impaired lung function confirming COPD is an independent risk factor for lung cancer. Oxidative stress and inflammation may be a key link between COPD and lung cancer, with numerous molecular markers being analysed to attempt to understand the pathway of lung cancer development. COPD negatively influences the ability to deliver radical treatment options, so attempts must be made to look for alternative methods of treating lung cancer, while aiming to manage the underlying COPD. Detailed assessment and management plans utilising the multidisciplinary team must be made for all lung cancer patients with COPD to provide the best care possible.
Keywords	Medicine ; R
Language	English
Publishing date	2011-01-01T00:00:00Z
Publisher	SAGE Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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