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  1. Article ; Online: A Named Entity Recognition Model Based on Multi-Task Learning and Cascading Pointer Network

    Geng Chaoyang / Liu Peng / Li Yi / Zhao Jiejie

    International Journal of Advanced Network, Monitoring, and Controls, Vol 7, Iss 3, Pp 52-

    2023  Volume 62

    Abstract: Because, the existing named entity recognition models lack the Specificity of the field, and most of their combine the prediction of entity Location and entity category, which results in the accumulation of errors. So, named entity recognition model ... ...

    Abstract Because, the existing named entity recognition models lack the Specificity of the field, and most of their combine the prediction of entity Location and entity category, which results in the accumulation of errors. So, named entity recognition model based on multi-task learning and pointer network is proposed, and innovations are made in the task Construction and domain entity information utilization in the model of Named entity recognition. This model is based on Transformer with multi-Head attention mechanism, and decomposes traditional tasks in entity recognition tasks and entity classification tasks, and carries out multi-tasks Task learning to reduce the accumulation of errors between tasks. Model in this paper also uses the similarity calculation based on the Comprehensive description of the entity category in entity classification Task for better pertinence of the domain entity. Experiments are conducted on public datasets and domain datasets to prove the advancement of the Model.
    Keywords named entity recognition ; multi-tasks task learning ; transformer ; Computer engineering. Computer hardware ; TK7885-7895 ; Electronic computers. Computer science ; QA75.5-76.95
    Subject code 006
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher Sciendo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Identifying Acss1, Mtfp1 and Oxct1 as key regulators and promising biomarkers of sarcopenia in various models.

    Cui, Hailong / Hu, Die / Liu, Yanling / Zhao, Jiejie

    Gene

    2023  Volume 896, Page(s) 148053

    Abstract: Mitochondrial dysfunction plays a critical role in muscular homeostasis, but the molecular mechanism underlying mitochondrial dynamics and sarcopenia awaits to be uncovered. We all know that malnutrition, cachexia, and type 2 diabetes are significant ... ...

    Abstract Mitochondrial dysfunction plays a critical role in muscular homeostasis, but the molecular mechanism underlying mitochondrial dynamics and sarcopenia awaits to be uncovered. We all know that malnutrition, cachexia, and type 2 diabetes are significant contributors to the development of sarcopenia.Therefore, we analyzed a bioinformatic analysis on cathectic differentially expressed genes (cDEGs), fasted differentially genes (fDEGs) and mitochondria-related genes. The overlapping genes identified were then validated by RT-qPCR and Western blotting experiments in various sarcopenia mice models and used to predict aging-related muscle loss in humans. First, the correlation analysis and PPI network indicated 6 overlapping candidates (Bdh1, Gdap1, Acss1, Mtfp1, Idh2, Oxct1) may constitute a regulatory effect in mitochondrial dynamics and muscle wasting. Next, we successfully established fasted, Lewis lung carcinoma (LLC) and Diabetes Mellitus (DM) induced sarcopenia mice models and verified that Acss1, Mtfp1 and Oxct1 shared common and significant variation tendency in these sarcopenia mice models. Further-more, Pearson correlation analysis showed that Acss1 was negatively related to the weight of gastrocnemius while Mtfp1 and Oxct1 displayed a significantly positive correlation with gastrocnemius weight in sarcopenic mice model induced by LLC, fasting and DM. What's more, ROC analysis based on human aging-related datasets indicated Acss1, Mtfp1, Oxct1 had outstanding diagnostic capabilities for sarcopenia. In general, we identified three hub genes (Acss1, Mtfp1 and Oxct1) that are strongly associated with mitochondrial dysfunction in sarcopenia and may provide novel and reliable indicators for screening, diagnosis, and prognosis, as well as potential therapeutic targets for patients with sarcopenia.
    MeSH term(s) Animals ; Humans ; Mice ; Aging/genetics ; Biomarkers ; Diabetes Mellitus, Type 2/genetics ; Mitochondrial Diseases ; Sarcopenia/diagnosis ; Sarcopenia/genetics ; Sarcopenia/pathology ; Coenzyme A-Transferases
    Chemical Substances Biomarkers ; MTFP1 protein, mouse ; MTFP1 protein, human ; 3-ketoacid CoA-transferase (EC 2.8.3.5) ; Coenzyme A-Transferases (EC 2.8.3.-)
    Language English
    Publishing date 2023-11-30
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 391792-7
    ISSN 1879-0038 ; 0378-1119
    ISSN (online) 1879-0038
    ISSN 0378-1119
    DOI 10.1016/j.gene.2023.148053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Research on Extraction Method of Financial Knowledge Based on How Net

    Geng Chaoyang / Zhao JieJie / Liu Peng / Yang Dan

    International Journal of Advanced Network, Monitoring, and Controls, Vol 8, Iss 1, Pp 50-

    2023  Volume 57

    Abstract: In order to obtain the knowledge information of financial texts more efficiently and make the extracted information such as entity relation attribute more accurate, this paper studies the grammatical features of financial news texts and the semantic ... ...

    Abstract In order to obtain the knowledge information of financial texts more efficiently and make the extracted information such as entity relation attribute more accurate, this paper studies the grammatical features of financial news texts and the semantic features of How Net, and puts forward the scheme of financial information extraction based on How Net. First, the phrase matching is carried out in the dictionary. Then the neural network is used for weighting, BiLSTM is used for character vector feature enhancement training, and then conditional random field (CRF) is used to complete named entity recognition, and then the relationship extraction of entity pairs from the dependency syntax is carried out to complete the research on the construction method of knowledge extraction of text in the financial field. The experimental results show that this model is superior to the other three models in entity recognition, and the overall performance is improved by about 1.2%. In relation extraction, the accuracy and recall rate of the model algorithm adopted in this paper are improved by 5% and 1.5% respectively, which shows that the improvement of the algorithm is effective.
    Keywords named entity identification in the financial sector ; relation extraction ; how net ; Computer engineering. Computer hardware ; TK7885-7895 ; Electronic computers. Computer science ; QA75.5-76.95
    Subject code 006
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Sciendo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Polyvinyl alcohol film with chlorine dioxide microcapsules can be used for blueberry preservation by slow-release of chlorine dioxide gas.

    Su, Hongxia / Chen, Zhanpeng / Zhao, Yuan / An, Jiejie / Huang, Haohe / Liu, Ren / Huang, Chongxing

    Frontiers in nutrition

    2023  Volume 10, Page(s) 1177950

    Abstract: Introduction: Chlorine dioxide (ClO: Methods: In this study, a ClO: Results: The self-releasing films had the best overall performance when the microcapsule content was 10% as the film's mechanical properties, thermal stability, and film barrier ... ...

    Abstract Introduction: Chlorine dioxide (ClO
    Methods: In this study, a ClO
    Results: The self-releasing films had the best overall performance when the microcapsule content was 10% as the film's mechanical properties, thermal stability, and film barrier properties were significantly improved. The inhibition rates of Listeria monocytogenes and Escherichia coli were 93.69% and 95.55%, respectively, and the mycelial growth of Staphylococcus griseus was successfully inhibited. The resulting ClO
    Discussion: Research analysis showed that films containing ClO
    Language English
    Publishing date 2023-04-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2023.1177950
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Erratum: [Corrigendum] Hepa1‑6‑FLuc cell line with the stable expression of firefly luciferase retains its primary properties with promising bioluminescence imaging ability.

    Li, Yasha / Liu, Mengnan / Cui, Jiejie / Yang, Ke / Zhao, Li / Gong, Mengjia / Wang, Yi / He, Yun / He, Tongchuan / Bi, Yang

    Oncology letters

    2023  Volume 25, Issue 5, Page(s) 187

    Abstract: This corrects the article DOI: 10.3892/ol.2018.8132.]. ...

    Abstract [This corrects the article DOI: 10.3892/ol.2018.8132.].
    Language English
    Publishing date 2023-03-27
    Publishing country Greece
    Document type Published Erratum
    ZDB-ID 2573196-8
    ISSN 1792-1082 ; 1792-1074
    ISSN (online) 1792-1082
    ISSN 1792-1074
    DOI 10.3892/ol.2023.13773
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Termination of a second-trimester pregnancy with placenta accreta spectrum disorder.

    Li, Qi / Zhang, Weishe / Hu, Caihong / Zhao, Yanhua / Pei, Chenlin / Wu, Xinhua / Fei, Kuilin / Peng, Qiaozhen / Zhang, Jiejie / Huang, Jingrui

    The Libyan journal of medicine

    2023  Volume 18, Issue 1, Page(s) 2258669

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Pregnancy ; Humans ; Female ; Pregnancy Trimester, Second ; Cesarean Section ; Placenta Accreta/diagnostic imaging ; Placenta Accreta/therapy ; Retrospective Studies ; Abortion, Induced
    Language English
    Publishing date 2023-09-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2273005-9
    ISSN 1819-6357 ; 1819-6357
    ISSN (online) 1819-6357
    ISSN 1819-6357
    DOI 10.1080/19932820.2023.2258669
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Analyzing the Spatial Heterogeneity of the Built Environment and Its Impact on the Urban Thermal Environment—Case Study of Downtown Shanghai

    Jiejie Han / Xi Zhao / Hao Zhang / Yu Liu

    Sustainability, Vol 13, Iss 11302, p

    2021  Volume 11302

    Abstract: Ongoing urban expansion has accelerated the explosive growth of urban populations and has led to a dramatic increase in the impervious surface area within urban areas. This, in turn, has exacerbated the surface heat island effect within cities. However, ... ...

    Abstract Ongoing urban expansion has accelerated the explosive growth of urban populations and has led to a dramatic increase in the impervious surface area within urban areas. This, in turn, has exacerbated the surface heat island effect within cities. However, the importance of the surface heat island effect within urban areas, scilicet the intra-SUHI effect, has attracted less concern. The aim of this study was to quantitatively explore the relationship between the spatial heterogeneity of a built environment and the intra-urban surface heat island (intra-SUHI) effect using the thermally sharpened land surface temperature (LST) and high-resolution land-use classification products. The results show that at the land parcel scale, the parcel-based relative intensity of intra-SUHI should be attributed to the land parcels featured with differential land developmental intensity. Furthermore, the partial least squares regression (PLSR) modeling quantified the relative importance of the spatial heterogeneity indices of the built environment that exhibit a negative contribution to decreasing the parcel-based intra-SUHI effect or a positive contribution to increasing the intra-SUHI effect. Finally, based on the findings of this study, some practical countermeasures towards mitigating the adverse intra-SUHI effect and improving urban climatic adaption are discussed.
    Keywords built-up environment ; spatial heterogeneity ; urban thermal environment ; blue–green space ; land use pattern ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 910
    Language English
    Publishing date 2021-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Targeting angiogenesis in myocardial infarction: Novel therapeutics (Review).

    Li, Jiejie / Zhao, Yuanyuan / Zhu, Wei

    Experimental and therapeutic medicine

    2021  Volume 23, Issue 1, Page(s) 64

    Abstract: Acute myocardial infarction (AMI) remains the main cause of mortality worldwide. Despite surgery and medical treatment, the non-regeneration of dead cardiomyocytes and the limited contractile ability of scar tissue can lead to heart failure. Therefore, ... ...

    Abstract Acute myocardial infarction (AMI) remains the main cause of mortality worldwide. Despite surgery and medical treatment, the non-regeneration of dead cardiomyocytes and the limited contractile ability of scar tissue can lead to heart failure. Therefore, restoring blood flow in the infarcted area is important for the repair of myocardial injury. The objective of the present review was to summarize the factors influencing angiogenesis after AMI, and to describe the application of angiogenesis for cardiac repair. Collectively, this review may be helpful for relevant studies and to provide insight into future therapeutic applications in clinical practice.
    Language English
    Publishing date 2021-11-22
    Publishing country Greece
    Document type Journal Article ; Review
    ZDB-ID 2683844-8
    ISSN 1792-1015 ; 1792-0981
    ISSN (online) 1792-1015
    ISSN 1792-0981
    DOI 10.3892/etm.2021.10986
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The preventive effects of aspirin on preeclampsia based on network pharmacology and bioinformatics.

    Zhang, Jiejie / Huang, Jingrui / Zhao, Yanhua / Zhang, Weishe

    Journal of human hypertension

    2021  Volume 36, Issue 8, Page(s) 753–759

    Abstract: This study aimed to reveal the key targets and molecular mechanisms of aspirin in preventing preeclampsia. We used bioinformatics databases to collect the candidate targets for aspirin and preeclampsia. The biological functions and signaling pathways of ... ...

    Abstract This study aimed to reveal the key targets and molecular mechanisms of aspirin in preventing preeclampsia. We used bioinformatics databases to collect the candidate targets for aspirin and preeclampsia. The biological functions and signaling pathways of the intersecting targets were analyzed by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG). Then, the hub targets were identified by cytoscape plugin cytoHubba from the protein-protein interaction network. We collected 90 targets for aspirin in preventing preeclampsia. The biological processes of the intersecting targets are mainly involved in xenobiotic metabolic process, inflammatory response, negative regulation of apoptotic process, and protein phosphorylation. The highly enriched pathways were FoxO signaling pathway, circadian rhythm, insulin resistance, arachidonic acid metabolism, and drug metabolism-cytochrome P450. The hub targets for aspirin in preventing preeclampsia were tumor protein p53 (TP53), C-X-C motif chemokine ligand 8 (CXCL8), mitogen-activated protein kinase 3 (MAPK3), mitogen-activated protein kinase 1 (MAPK1), mitogen-activated protein kinase 14 (MAPK14), epidermal growth factor receptor (EGFR), estrogen receptor (ESR1), and prostaglandin-endoperoxide synthase 2 (PTGS2). Molecular docking results showed good bindings between the proteins and aspirin. In conclusion, these findings highlight the key targets and molecular mechanisms of aspirin in preventing preeclampsia.
    MeSH term(s) Aspirin/pharmacology ; Aspirin/therapeutic use ; Computational Biology/methods ; Female ; Gene Regulatory Networks ; Humans ; Molecular Docking Simulation ; Network Pharmacology ; Pre-Eclampsia/genetics ; Pre-Eclampsia/prevention & control ; Pregnancy
    Chemical Substances Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2021-06-24
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639472-3
    ISSN 1476-5527 ; 0950-9240
    ISSN (online) 1476-5527
    ISSN 0950-9240
    DOI 10.1038/s41371-021-00568-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Application of Bioprinting in Ophthalmology.

    Wang, Yanfang / Wang, Jiejie / Ji, Ziyu / Yan, Wei / Zhao, Hong / Huang, Wenhua / Liu, Huan

    International journal of bioprinting

    2022  Volume 8, Issue 2, Page(s) 552

    Abstract: Three-dimensional (3D) bioprinting is an emerging technology that is widely used in regenerative medicine. With the continuous development of the technology, it has attracted great attention and demonstrated promising prospects in ophthalmologic ... ...

    Abstract Three-dimensional (3D) bioprinting is an emerging technology that is widely used in regenerative medicine. With the continuous development of the technology, it has attracted great attention and demonstrated promising prospects in ophthalmologic applications. In this paper, we review the three main types of 3D bioprinting technologies: Vat polymerization-based bioprinting, extrusion-based bioprinting, and jetting-based bioprinting. We also present in this review the analysis of the usage of both natural and synthesized hydrogels as well as the types of cells adopted for bioinks. Cornea and retina are the two main types of ocular tissues developed in bioprinting, while other device and implants were also developed for the ocular disease treatment. We also summarize the advantages and limitations as well as the future prospects of the current bioprinting technologies based on systematic reviews.
    Language English
    Publishing date 2022-02-22
    Publishing country Singapore
    Document type Journal Article ; Review
    ZDB-ID 2834694-4
    ISSN 2424-8002 ; 2424-8002
    ISSN (online) 2424-8002
    ISSN 2424-8002
    DOI 10.18063/ijb.v8i2.552
    Database MEDical Literature Analysis and Retrieval System OnLINE

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