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Article: Imaging features of fungal pneumonia in haematopoietic stem cell transplant patients.

Revels, Jonathan W / Fadl, Shaimaa A / Wang, Sherry S / Ladumor, Heta / Xu, Haodong / Kicska, Gregory

2021 Volume 86, Page(s) e335–e343

Abstract: Patients who have received haematopoietic stem cell transplantation (HSCT) have a high rate of pulmonary complications, and in this immunosuppressed population, fungal pneumonia is of great concern. Fungal pneumonia can have a similar appearance to non- ... ...

Abstract	Patients who have received haematopoietic stem cell transplantation (HSCT) have a high rate of pulmonary complications, and in this immunosuppressed population, fungal pneumonia is of great concern. Fungal pneumonia can have a similar appearance to non-infectious pulmonary processes in HSCT patients, and radiologists should be familiar with the subtle features that may help to differentiate these disease entities. The focus of this article is on the diagnosis of fungal pneumonia in HSCT patients with an emphasis on radiologists' roles in establishing the diagnosis of fungal pneumonia and the guidance of clinical management.
Language	English
Publishing date	2021-06-07
Publishing country	Poland
Document type	Journal Article ; Review
ZDB-ID	2675143-4
ISSN	1899-0967 ; 1733-134X
ISSN (online)	1899-0967
ISSN	1733-134X
DOI	10.5114/pjr.2021.107057
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Article ; Online: Chinese Ring-Sword sign in intramural hematoma: feature of intramural blood pool.

Revels, Jonathan W / Akaike, Gensuke / Kicska, Gregory / Cham, Matthew D

Abdominal radiology (New York)

2019 Volume 45, Issue 1, Page(s) 234–236

MeSH term(s)	Aneurysm, Dissecting/complications ; Aneurysm, Dissecting/diagnostic imaging ; Aorta/diagnostic imaging ; Aortic Diseases/diagnostic imaging ; Computed Tomography Angiography/methods ; Hematoma/complications ; Hematoma/diagnostic imaging ; Humans ; Syndrome ; Ulcer/complications ; Ulcer/diagnostic imaging
Language	English
Publishing date	2019-11-04
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2839786-1
ISSN	2366-0058 ; 2366-004X
ISSN (online)	2366-0058
ISSN	2366-004X
DOI	10.1007/s00261-019-02304-9
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Zs.A 1262: Show issues

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Article ; Online: Lower attenuation and higher kurtosis of coronary artery calcification associated with vulnerable plaque - an agatston score propensity-matched CT radiomics study.

Huang, Eric Po-Yu / Lin, Huey-Shyan / Chen, Yi-Chun / Li, Yi-He / Huang, Yi-Luan / Ju, Yu-Jeng / Yu, Hsien-Chung / Kicska, Gregory A / Wu, Ming-Ting

BMC cardiovascular disorders

2023 Volume 23, Issue 1, Page(s) 158

Abstract: Background: Coronary artery calcification (CAC) burden assessed by Agatston score (AS) is currently recommended to stratify patients at risk for future acute coronary syndrome (ACS). Besides the CAC burden, the biostructure of CAC may also play a vital ... ...

Abstract	Background: Coronary artery calcification (CAC) burden assessed by Agatston score (AS) is currently recommended to stratify patients at risk for future acute coronary syndrome (ACS). Besides the CAC burden, the biostructure of CAC may also play a vital role in the vulnerability of CAC, which CT radiomics could reveal. Propensity-score matching of the traditional risk factors and CAC burden between the ACS and asymptomatic groups could radically remove biases and allow the exploration of characteristic features of CAC in ACS. Methods: We retrospectively identified 77 patients with ACS who had a CAC scan before percutaneous coronary intervention between 2016 and 2019. These 77 patients were one-to-two propensity-score matched for traditional risk factors of ACS and AS ranks to select 154 subjects from 2890 asymptomatic subjects. A validation cohort of 30 subjects was also enrolled. Radiomics features of each plaque were extracted and averaged in each person. Conditional logistic regression and area-under-curve analysis were used for statistical analysis. Results: A higher number of coronary segments involved, lower mean, median, first quartile, and standard deviation of attenuation, and increased kurtosis of attenuation of CAC were associated with the ACS group compared to the control group (p < 0.05 for all). Multivariable analysis showed that the lower median attenuation (OR = 0.969, p < 0.001) and higher Kurtosis (OR = 18.7, p < 0.001) were associated with the ACS group. The median attenuation and kurtosis significantly increase across AS ranks 1 to 4 (p = 0.001). The AUC of kurtosis (0.727) and median attenuation (0.66) were both significantly higher than that of the standard AS (AUC = 0.502) and the number of TRF (AUC = 0.537). The best cut-off of kurtosis at 2.74 yielded an accuracy of 74%, and the cut-off of median attenuation at 196 yielded an accuracy of 68%. The accuracy of kurtosis was 64%, and the accuracy of median attenuation was 55% in the validation cohort. Conclusion: After propensity-matching traditional risk factors and CAC burden, CT radiomics highlighted that lower median attenuation and higher kurtosis were the CAC characteristics of vulnerable plaques. These features improve the understanding of the biomechanics of CAC evolution and enhance the value of CAC scan in ACS risk assessment.
MeSH term(s)	Humans ; Acute Coronary Syndrome/diagnostic imaging ; Acute Coronary Syndrome/etiology ; Acute Coronary Syndrome/therapy ; Coronary Angiography ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/therapy ; Coronary Artery Disease/complications ; Coronary Vessels/diagnostic imaging ; Plaque, Atherosclerotic/complications ; Predictive Value of Tests ; Retrospective Studies ; Risk Factors ; Tomography, X-Ray Computed ; Vascular Calcification/diagnostic imaging ; Vascular Calcification/therapy
Language	English
Publishing date	2023-03-27
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2059859-2
ISSN	1471-2261 ; 1471-2261
ISSN (online)	1471-2261
ISSN	1471-2261
DOI	10.1186/s12872-023-03162-6
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Article ; Online: Radiographic Signs and Patterns in Interstitial Lung Disease.

Nasrullah, Ayesha / Fadl, Shaimaa / Ahuja, Jitesh / Xu, Haodong / Kicska, Gregory

Seminars in roentgenology

2018 Volume 54, Issue 1, Page(s) 66–72

MeSH term(s)	Humans ; Lung/diagnostic imaging ; Lung Diseases, Interstitial/diagnostic imaging ; Tomography, X-Ray Computed/methods
Language	English
Publishing date	2018-12-30
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	80310-8
ISSN	1558-4658 ; 0037-198X
ISSN (online)	1558-4658
ISSN	0037-198X
DOI	10.1053/j.ro.2018.12.009
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Article ; Online: Review of Chest Radiograph Findings of COVID-19 Pneumonia and Suggested Reporting Language.

Litmanovich, Diana E / Chung, Michael / Kirkbride, Rachael R / Kicska, Gregory / Kanne, Jeffrey P

Journal of thoracic imaging

2020 Volume 35, Issue 6, Page(s) 354–360

Abstract: The diagnosis of coronavirus disease 2019 (COVID-19) is confirmed by reverse transcription polymerase chain reaction. The utility of chest radiography (CXR) remains an evolving topic of discussion. Current reports of CXR findings related to COVID-19 ... ...

Abstract	The diagnosis of coronavirus disease 2019 (COVID-19) is confirmed by reverse transcription polymerase chain reaction. The utility of chest radiography (CXR) remains an evolving topic of discussion. Current reports of CXR findings related to COVID-19 contain varied terminology as well as various assessments of its sensitivity and specificity. This can lead to a misunderstanding of CXR reports and makes comparison between examinations and research studies challenging. With this need for consistency, we propose language for standardized CXR reporting and severity assessment of persons under investigation for having COVID-19, patients with a confirmed diagnosis of COVID-19, and patients who may have radiographic findings typical or suggestive of COVID-19 when the diagnosis is not suspected clinically. We recommend contacting the referring providers to discuss the likelihood of viral infection when typical or indeterminate features of COVID-19 pneumonia on CXR are present as an incidental finding. In addition, we summarize the currently available literature related to the use of CXR for COVID-19 and discuss the evolving techniques of obtaining CXR in COVID-19-positive patients. The recently published expert consensus statement on reporting chest computed tomography findings related to COVID-19, endorsed by the Radiological Society of North American (RSNA), the Society of Thoracic Radiology (STR), and American College of Radiology (ACR), serves as the framework for our proposal.
MeSH term(s)	COVID-19/diagnostic imaging ; Humans ; Lung/diagnostic imaging ; Radiography, Thoracic/methods ; SARS-CoV-2 ; Sensitivity and Specificity ; Tomography, X-Ray Computed/methods
Keywords	covid19
Language	English
Publishing date	2020-06-06
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	632900-7
ISSN	1536-0237 ; 0883-5993
ISSN (online)	1536-0237
ISSN	0883-5993
DOI	10.1097/RTI.0000000000000541
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Zs.A 2187: Show issues

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Article ; Online: Comprehensive review of pericardial diseases using different imaging modalities.

Fadl, Shaimaa A / Nasrullah, Ayesha / Harris, Andrew / Edwards, Rachael / Kicska, Gregory

The international journal of cardiovascular imaging

2020 Volume 36, Issue 5, Page(s) 947–969

Abstract: Pericardial abnormalities are common cardiovascular disease entity, which are encountered in various clinical settings. Imaging plays an integral role in evaluation of pericardial abnormalities. The appropriate use of multiple imaging modalities is ... ...

Abstract	Pericardial abnormalities are common cardiovascular disease entity, which are encountered in various clinical settings. Imaging plays an integral role in evaluation of pericardial abnormalities. The appropriate use of multiple imaging modalities is crucial to initiate the diagnosis and guide the referring providers to establish a management plan. Echocardiography (echo) is the initial imaging modality of choice. Computed tomography (CT) and magnetic resonance imaging (MRI) are complementary imaging tools with better tissue characterization. Pericardial abnormalities include pericardial effusion, pericarditis, pericardial constriction, tamponade, pneumopericardium, pericardial rupture, fistulas, congenital abnormalities, and pericardial tumors. Pericardial effusion is a common clinical entity, where there is accumulation of fluid in the pericardial sac. Pericarditis can be acute, incessant, chronic, or recurrent. Pericardial thickening or enhancement are the main CT findings in acute pericarditis. Pericardial constriction results into diastolic heart failure. Differentiating constrictive pericarditis from restrictive cardiomyopathy is important, since these conditions can present with similar clinical and hemodynamic findings and both have different management. Right atrial or right ventricular compression by the pericardial sac contents should raise the suspicion for tamponade. Immediate pericardiocentesis to release the elevated intra-pericardial pressure can be lifesaving. Pericardial rupture is a serious condition that can occur after trauma and can lead to cardiac herniation. The main purpose of this article is to do a comprehensive review of the imaging appearance of pericardial diseases on different imaging modalities and establish a structured diagnostic approach for pericardial diseases to appropriately guide management.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Cardiac Tamponade/diagnostic imaging ; Echocardiography ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Multimodal Imaging ; Pericardial Effusion/diagnostic imaging ; Pericarditis/diagnostic imaging ; Pericarditis, Constrictive/diagnostic imaging ; Pericardium/diagnostic imaging ; Pneumopericardium/diagnostic imaging ; Predictive Value of Tests ; Tomography, Emission-Computed ; Tomography, X-Ray Computed ; Young Adult
Language	English
Publishing date	2020-02-11
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2055311-0
ISSN	1875-8312 ; 1573-0743 ; 1569-5794 ; 0167-9899
ISSN (online)	1875-8312 ; 1573-0743
ISSN	1569-5794 ; 0167-9899
DOI	10.1007/s10554-020-01784-x
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Zs.A 2104: Show issues

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Article ; Online: The functional single ventricle: how imaging guides treatment.

Edwards, Rachael M / Reddy, Gautham P / Kicska, Gregory

Clinical imaging

2016 Volume 40, Issue 6, Page(s) 1146–1155

Abstract: Functional single ventricle (FSV) encompasses a spectrum of severe congenital heart disease. Patients with FSV are living longer than decades prior resulting in more frequent imaging both for surgical planning and functional evaluation. At each stage of ... ...

Abstract	Functional single ventricle (FSV) encompasses a spectrum of severe congenital heart disease. Patients with FSV are living longer than decades prior resulting in more frequent imaging both for surgical planning and functional evaluation. At each stage of surgical intervention, imaging plays a critical role in detecting postoperative complications and preprocedural planning. This article describes the unique imaging findings, including complications, that are most important to the referring physician or surgeon at each surgical stage of FSV management. A description of lesions that embody the diagnosis of FSV is also included.
MeSH term(s)	Angiography/methods ; Cleft Palate/diagnostic imaging ; Ear, External/diagnostic imaging ; Echocardiography/methods ; Fontan Procedure/methods ; Heart Defects, Congenital/diagnostic imaging ; Heart Defects, Congenital/surgery ; Heart Ventricles/abnormalities ; Heart Ventricles/diagnostic imaging ; Humans ; Magnetic Resonance Angiography/methods ; Microcephaly/diagnostic imaging ; Micrognathism/diagnostic imaging ; Multidetector Computed Tomography/methods ; Palliative Care ; Postoperative Complications/diagnostic imaging ; Postoperative Complications/etiology ; Pulmonary Artery/abnormalities ; Pulmonary Artery/diagnostic imaging ; Retrospective Studies ; Surgery, Computer-Assisted/methods ; Treatment Outcome ; Tricuspid Atresia/diagnostic imaging
Language	English
Publishing date	2016-11
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1028123-x
ISSN	1873-4499 ; 0899-7071
ISSN (online)	1873-4499
ISSN	0899-7071
DOI	10.1016/j.clinimag.2016.08.003
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Article ; Online: The novel coronavirus disease (COVID-19) complicated by pulmonary embolism and acute respiratory distress syndrome.

Li, Ting / Cheng, Guang-Shing / Pipavath, Sudhakar N J / Kicska, Gregory A / Liu, Liangjin / Kinahan, Paul E / Wu, Wei

Journal of medical virology

2020 Volume 92, Issue 10, Page(s) 2205–2208

Abstract: Acute respiratory distress syndrome and coagulopathy played an important role in morbidity and mortality of severe COVID-19 patients. A higher frequency of pulmonary embolism (PE) than expected in COVID-19 patients was recently reported. The presenting ... ...

Abstract	Acute respiratory distress syndrome and coagulopathy played an important role in morbidity and mortality of severe COVID-19 patients. A higher frequency of pulmonary embolism (PE) than expected in COVID-19 patients was recently reported. The presenting symptoms for PE were untypical including dyspnea, which is one of the major symptoms in severe COVID-19, especially in those patients with acute respiratory distress syndrome (ARDS). We reported two COVID-19 cases with coexisting complications of PE and ARDS, aiming to consolidate the emerging knowledge of this global health emergency and raise the awareness that the hypoxemia or severe dyspnea in COVID-19 may be related to PE and not necessarily always due to the parenchymal disease.
MeSH term(s)	Acute Disease ; Aged ; Biomarkers/blood ; Blood Platelets/drug effects ; Blood Platelets/pathology ; Blood Platelets/virology ; COVID-19/complications ; COVID-19/diagnostic imaging ; COVID-19/drug therapy ; COVID-19/virology ; Ceftazidime/therapeutic use ; Dyspnea/physiopathology ; Fibrin Fibrinogen Degradation Products/metabolism ; Heparin/therapeutic use ; Humans ; Hypoxia/physiopathology ; Lung/blood supply ; Lung/drug effects ; Lung/pathology ; Lung/virology ; Male ; Methylprednisolone/therapeutic use ; Middle Aged ; Pulmonary Embolism/complications ; Pulmonary Embolism/diagnostic imaging ; Pulmonary Embolism/drug therapy ; Pulmonary Embolism/virology ; Respiratory Distress Syndrome/complications ; Respiratory Distress Syndrome/diagnostic imaging ; Respiratory Distress Syndrome/drug therapy ; Respiratory Distress Syndrome/virology ; Ribavirin/therapeutic use ; SARS-CoV-2/pathogenicity ; Tomography, X-Ray Computed ; Treatment Outcome
Chemical Substances	Biomarkers ; Fibrin Fibrinogen Degradation Products ; fibrin fragment D ; Ribavirin (49717AWG6K) ; Heparin (9005-49-6) ; Ceftazidime (9M416Z9QNR) ; Methylprednisolone (X4W7ZR7023)
Keywords	covid19
Language	English
Publishing date	2020-06-12
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	752392-0
ISSN	1096-9071 ; 0146-6615
ISSN (online)	1096-9071
ISSN	0146-6615
DOI	10.1002/jmv.26068
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Zs.A 1320: Show issues

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Article ; Online: Policies and Guidelines for COVID-19 Preparedness: Experiences from the University of Washington.

Mossa-Basha, Mahmud / Medverd, Jonathan / Linnau, Ken F / Lynch, John B / Wener, Mark H / Kicska, Gregory / Staiger, Thomas / Sahani, Dushyant V

Radiology

2020 Volume 296, Issue 2, Page(s) E26–E31

Abstract: The coronavirus disease 2019 (COVID-19) pandemic initially manifested in the United States in the greater Seattle area and has rapidly progressed across the nation in the past 2 months, with the United States having the highest number of cases in the ... ...

Abstract	The coronavirus disease 2019 (COVID-19) pandemic initially manifested in the United States in the greater Seattle area and has rapidly progressed across the nation in the past 2 months, with the United States having the highest number of cases in the world. Radiology departments play a critical role in policy and guideline development both for the department and for the institutions, specifically in planning diagnostic screening, triage, and management of patients. In addition, radiology workflows, volumes, and access must be optimized in preparation for the expected surges in the number of patients with COVID-19. In this article, the authors discuss the processes that have been implemented at the University of Washington in managing the COVID-19 pandemic as well in preparing for patient surges, which may provide important guidance for other radiology departments who are in the early stages of preparation and management.
MeSH term(s)	Air Pollutants, Occupational/analysis ; Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/diagnosis ; Coronavirus Infections/diagnostic imaging ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Health Policy ; Humans ; Infection Control/organization & administration ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Mass Screening/methods ; Pandemics/prevention & control ; Personal Protective Equipment ; Pneumonia, Viral/diagnostic imaging ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; Practice Guidelines as Topic ; Radiology Department, Hospital/organization & administration ; SARS-CoV-2 ; Washington
Chemical Substances	Air Pollutants, Occupational
Keywords	covid19
Language	English
Publishing date	2020-07-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	80324-8
ISSN	1527-1315 ; 0033-8419
ISSN (online)	1527-1315
ISSN	0033-8419
DOI	10.1148/radiol.2019201326
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Article ; Online: Statement from the North American Society for Cardiovascular Imaging on imaging strategies to reduce the scarcity of healthcare resources during the COVID-19 outbreak.

Kicska, Gregory / Litmanovich, Diana E / Ordovas, Karen G / Young, Phillip M / Dennie, Carole / Truong, Quynh A / Abbara, Suhny / Kirsch, Jacobo

The international journal of cardiovascular imaging

2020 Volume 36, Issue 8, Page(s) 1387–1393

Abstract: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an evolving global pandemic that is predicted to strain healthcare resources at multiple locations throughout North America and the World. As ... ...

Abstract	Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an evolving global pandemic that is predicted to strain healthcare resources at multiple locations throughout North America and the World. As of April 6, 2020, the apex of infection rates is predicted to occur within 1 to 5 weeks at various locations. Widespread reports of personal protective equipment (PPE) shortages, and healthcare worker exposure to disease have become commonplace. To mitigate this crisis, we are suggesting imaging strategies that aim to use the least PPE, require the smallest number of potential staff exposures, and streamlines utilization of imaging. They are broadly organized by (1) substituting a noninvasive diagnostic test in place of a semi-invasive or invasive diagnostic tests, and (2) consolidating diagnostic imaging.
MeSH term(s)	Betacoronavirus ; COVID-19 ; Cardiovascular Diseases/diagnostic imaging ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Decision Making ; Health Resources/supply & distribution ; Humans ; Infection Control/organization & administration ; North America/epidemiology ; Occupational Exposure/prevention & control ; Pandemics/prevention & control ; Personal Protective Equipment/supply & distribution ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; SARS-CoV-2 ; Societies, Medical
Keywords	covid19
Language	English
Publishing date	2020-05-30
Publishing country	United States
Document type	Editorial
ZDB-ID	2055311-0
ISSN	1875-8312 ; 1573-0743 ; 1569-5794 ; 0167-9899
ISSN (online)	1875-8312 ; 1573-0743
ISSN	1569-5794 ; 0167-9899
DOI	10.1007/s10554-020-01861-1
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