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  1. AU=Zein Ahmad Fariz Malvi Zamzam
  2. AU="Delgado, Fernanda"
  3. AU="André Scherag"
  4. AU="Simring, Steven"
  5. AU="Gowdy, John M."
  6. AU="Yeldandi, Anjana"
  7. AU="Mierdel, Katrin"
  8. AU="Karaaslan, Ayse"
  9. AU="Fuchs, Ch"
  10. AU="Toro, Diana"
  11. AU="Lindner, Robert"
  12. AU="Meshkat, Shakila"
  13. AU="Geist, Felix"
  14. AU="Xiong, Yinyi"
  15. AU="Larciprete, R"
  16. AU="Camila Mugnai Vieira"
  17. AU="Michael Sjöström"
  18. AU="Bouchau, Robin"
  19. AU="Shahabi Rabori, Venus"
  20. AU="Jeronimo, Matthew"
  21. AU="Misra, Maitreyi"
  22. AU="Liu, Xuping"
  23. AU="Corinna Lüneburg"
  24. AU="Clement, Lionel C"
  25. AU="Parkhill, Julian"
  26. AU="Wiita, Arun P"
  27. AU=Lubrano Riccardo
  28. AU=Biggs Andrew
  29. AU="Lian, Kejian"
  30. AU="Almutairi, Abdulrahman"
  31. AU="Cosculluela-Pueyo, Rafaél"
  32. AU="Gehrs, Teresa"
  33. AU="Munir, Atif"
  34. AU="Ou, Ya-Nan"
  35. AU=Brown James E AU=Brown James E
  36. AU="Wang, Zhongmin"
  37. AU="Lemieux, Audrée"
  38. AU="Abdelhameed, Mohamed F"
  39. AU="Schaible, Lonnie M"
  40. AU="Yazie, Taklo Simeneh Yazie"
  41. AU="Jude Orumuah Agbugui"
  42. AU="Kruse, Robert L"
  43. AU="Shyama Nandakumar"
  44. AU="Gelb, M"
  45. AU="Gasparini, L"
  46. AU="Ulvila, J"
  47. AU="Länsimies, Helena"

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  1. Artikel ; Online: A patient with porocarcinoma of the lower extremity and lung metastasis: a rare case report.

    Zein, Ahmad Fariz Malvi Zamzam / Luthfi, Mohamad / Putro, Widyatmiko Arifin / Nurbaiti, Nurbaiti

    Medicine and pharmacy reports

    2023  Band 96, Heft 3, Seite(n) 318–322

    Abstract: Background: Porocarcinoma is a rare cancer of the developing sweat glands. It often occurs in older adults and frequently affects the head, neck, and extremities. We report a rare case of metastatic porocarcinoma with intriguing approach of the ... ...

    Abstract Background: Porocarcinoma is a rare cancer of the developing sweat glands. It often occurs in older adults and frequently affects the head, neck, and extremities. We report a rare case of metastatic porocarcinoma with intriguing approach of the diagnosis and management due to limited resource setting.
    Case report: A 60-year-old man with a history of type 2 diabetes mellitus presented with nodules on the left foot with no palpable lymph node. A chest radiograph revealed multiple coin lesions and histopathological findings were suggestive for porocarcinoma. We assessed the case as a metastatic porocarcinoma in a patient with uncontrolled type 2 diabetes mellitus. Surgery was performed in the initial phase of treatment, consisting of below-knee amputation. The patient refused the planned chemotherapy in the referral hospital and then underwent other modalities of palliative care. He passed away eleven months after the initial diagnosis.
    Conclusions: Metastatic porocarcinoma is a rare oncological case with a challenging approach of the diagnosis and management. High awareness of clinical clues in rare cancer is needed for early diagnosis and prompt treatment, especially in limited resource settings.
    Sprache Englisch
    Erscheinungsdatum 2023-07-27
    Erscheinungsland Romania
    Dokumenttyp Case Reports
    ZDB-ID 2974425-8
    ISSN 2668-0572 ; 2602-0807
    ISSN (online) 2668-0572
    ISSN 2602-0807
    DOI 10.15386/mpr-2387
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Effect of colchicine on mortality in patients with COVID-19 - A systematic review and meta-analysis.

    Zein, Ahmad Fariz Malvi Zamzam / Raffaello, Wilson Matthew

    Diabetes & metabolic syndrome

    2022  Band 16, Heft 2, Seite(n) 102395

    Abstract: Background and aim: This systematic review and meta-analysis aimed to evaluate the latest evidence on the association between colchicine and mortality in patients with COVID-19.: Methods: We performed a comprehensive literature search from the PubMed, ...

    Abstract Background and aim: This systematic review and meta-analysis aimed to evaluate the latest evidence on the association between colchicine and mortality in patients with COVID-19.
    Methods: We performed a comprehensive literature search from the PubMed, Scopus, Embase, EuropePMC, and Clinicaltrials.gov up until 02 January 2022. We include randomized controlled trials (RCTs) and observational studies reporting colchicine use in patients with COVID-19 and mortality within 30 days. The intervention group was patients given colchicine during the course of treatment. The control group was patients given placebo or standard of care at the respective institutions. The outcome was mortality. The effect estimate was reported as risk ratio (RR).
    Results: There were 12 studies comprising of 6953 patients included in this meta-analysis. Mortality rate was 0.18 [95%CI 0.10, 0.26] in the colchicine group and 0.26 [95%CI 0.15, 0.38] in the control group. Colchicine was associated with reduction in mortality (RR 0.66 [95%CI 0.53, 0.83], p < 0.001; I
    Conclusion: Though the meta-analysis showed decreased mortality with colchicine in patients with COVID-19, the meta-analysis of randomized trials did not show any significant effect of colchicine on mortality.
    Mesh-Begriff(e) Aged ; Anti-Inflammatory Agents/administration & dosage ; COVID-19/drug therapy ; COVID-19/epidemiology ; COVID-19/mortality ; Colchicine/administration & dosage ; Comorbidity ; Diabetes Mellitus/epidemiology ; Female ; Humans ; Hypertension/epidemiology ; Male ; Middle Aged ; Odds Ratio ; Randomized Controlled Trials as Topic ; SARS-CoV-2/physiology ; Virus Replication/drug effects
    Chemische Substanzen Anti-Inflammatory Agents ; Colchicine (SML2Y3J35T)
    Sprache Englisch
    Erscheinungsdatum 2022-01-12
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 2273766-2
    ISSN 1878-0334 ; 1871-4021
    ISSN (online) 1878-0334
    ISSN 1871-4021
    DOI 10.1016/j.dsx.2022.102395
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Sofosbuvir with daclatasvir and the outcomes of patients with COVID-19: a systematic review and meta-analysis with GRADE assessment.

    Zein, Ahmad Fariz Malvi Zamzam / Sulistiyana, Catur Setiya / Raffaello, Wilson Matthew / Wibowo, Arief / Pranata, Raymond

    Postgraduate medical journal

    2023  Band 98, Heft 1161, Seite(n) 509–514

    Abstract: Purpose: This systematic review and meta-analysis aimed to evaluate the effect of sofosbuvir/daclatasvir (SOF/DCV) on mortality, the need for intensive care unit (ICU) admission or invasive mechanical ventilation (IMV) and clinical recovery in patients ... ...

    Abstract Purpose: This systematic review and meta-analysis aimed to evaluate the effect of sofosbuvir/daclatasvir (SOF/DCV) on mortality, the need for intensive care unit (ICU) admission or invasive mechanical ventilation (IMV) and clinical recovery in patients with COVID-19.
    Methods: We performed a systematic literature search through the PubMed, Scopus and Embase from the inception of databases until 6 April 2021. The intervention group was SOF/DCV, and the control group was standard of care. The primary outcome was mortality, defined as clinically validated death. The secondary outcomes were (1) the need for ICU admission or IMV and (2) clinical recovery. The pooled effect estimates were reported as risk ratios (RRs).
    Results: There were four studies with a total of 231 patients in this meta-analysis. Three studies were randomised controlled trial, and one study was non-randomised. SOF/DCV was associated with lower mortality (RR: 0.31 (0.12, 0.78); p=0.013; I2: 0%) and reduced need for ICU admission or IMV (RR: 0.35 (0.18, 0.69); p=0.002; I2: 0%). Clinical recovery was achieved more frequently in the SOF/DCV (RR: 1.20 (1.04, 1.37); p=0.011; I2: 21.1%). There was a moderate certainty of evidence for mortality and need for ICU/IMV outcome, and a low certainty of evidence for clinical recovery. The absolute risk reductions were 140 fewer per 1000 for mortality and 186 fewer per 1000 for the need for ICU/IMV. The increase in clinical recovery was 146 more per 1000.
    Conclusion: SOF/DCV may reduce mortality rate and need for ICU/IMV in patients with COVID-19 while increasing the chance for clinical recovery.
    Protocol registration: PROSPERO: CRD42021247510.
    Mesh-Begriff(e) Humans ; COVID-19 ; GRADE Approach ; Imidazoles/therapeutic use ; Sofosbuvir/therapeutic use ; COVID-19 Drug Treatment/methods ; Controlled Clinical Trials as Topic
    Chemische Substanzen daclatasvir (LI2427F9CI) ; Imidazoles ; Sofosbuvir (WJ6CA3ZU8B)
    Sprache Englisch
    Erscheinungsdatum 2023-04-08
    Erscheinungsland England
    Dokumenttyp Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 80325-x
    ISSN 1469-0756 ; 0032-5473
    ISSN (online) 1469-0756
    ISSN 0032-5473
    DOI 10.1136/postgradmedj-2021-140287
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Dipeptidyl peptidase-4 (DPP-IV) inhibitor was associated with mortality reduction in COVID-19 - A systematic review and meta-analysis.

    Zein, Ahmad Fariz Malvi Zamzam / Raffaello, Wilson Matthew

    Primary care diabetes

    2021  Band 16, Heft 1, Seite(n) 162–167

    Abstract: Introduction: This systematic review and meta-analysis aimed to synthesize the latest evidence on the effect of dipeptidyl peptidase-4 (DPP-IV) inhibitor in patients with COVID-19.: Methods: We performed a systematic literature search from the PubMed, ...

    Abstract Introduction: This systematic review and meta-analysis aimed to synthesize the latest evidence on the effect of dipeptidyl peptidase-4 (DPP-IV) inhibitor in patients with COVID-19.
    Methods: We performed a systematic literature search from the PubMed, Scopus, Embase, and Clinicaltrials.gov up until 15 July 2021. Studies that met the following criteria were included: prospective or retrospective observational studies or case series or randomized controlled trials (RCTs) reporting DPP-IV inhibitor use in patients with COVID-19 and mortality. The intervention group was patients receiving DPP-IV inhibitor. The control group was patients that did not receive DPP-IV inhibitor. The outcome was mortality reported as odds ratio (OR).
    Results: There were 11 studies consisting of 5950 patients in this meta-analysis. DPP-IV inhibitor use was associated with reduced mortality (OR 0.75 [0.56, 0.99], p = 0.043, I
    Conclusion: This meta-analysis showed that DPP-IV inhibitor was associated with reduced mortality in patients with COVID-19.
    Mesh-Begriff(e) COVID-19 ; Diabetes Mellitus, Type 2 ; Dipeptidyl-Peptidase IV Inhibitors/adverse effects ; Humans ; Hypoglycemic Agents/adverse effects ; SARS-CoV-2
    Chemische Substanzen Dipeptidyl-Peptidase IV Inhibitors ; Hypoglycemic Agents
    Sprache Englisch
    Erscheinungsdatum 2021-12-13
    Erscheinungsland England
    Dokumenttyp Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 2273997-X
    ISSN 1878-0210 ; 1751-9918
    ISSN (online) 1878-0210
    ISSN 1751-9918
    DOI 10.1016/j.pcd.2021.12.008
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: The Proportion of Acute Transfusion Reaction at Outpatient Blood Transfusion Unit In Tertiary Hospital in Indonesia

    Ahmad Fariz Malvi Zamzam Zein / Lugyanti Sukrisman

    Jurnal Penyakit Dalam Indonesia, Vol 7, Iss 2, Pp 95-

    2020  Band 99

    Abstract: Introduction. Acute transfusion reaction (ATR) is an important issue related to patient safety. The prevalence of ATR at tertiary hospital in Indonesia is 0.5%. This study was aimed to determine the proportion of ATR in outpatient blood transfusion unit ... ...

    Abstract Introduction. Acute transfusion reaction (ATR) is an important issue related to patient safety. The prevalence of ATR at tertiary hospital in Indonesia is 0.5%. This study was aimed to determine the proportion of ATR in outpatient blood transfusion unit at tertiary hospital. Method. This retrospective study implemented data from medical records of adult patients who underwent blood transfusion in outpatient blood transfusion unit, Cipto Mangunkusumo Hospital between August – October 2014. The blood components included packed red cells (PRC), thrombocyte concentrate (TC), fresh frozen plasma (FFP), and cryoprecipitate. We recorded the administration of premedication and ATR-related symptoms/signs. The ATR report was based on WHO classification. Results. There were 1,010 blood transfusions during the study period. The distribution of blood components were PRC (n=802, 79.4%), PC (n=74, 7.3%), FFP (n=43, 4.3%), and cryoprecipitate (n=91, 9.0%). The premedication was administered in 21 transfusions (2.1%). There were 11 ATRs with WHO category 1 (1.1%), no other categories were reported. Based on blood component, the ATR occurred predominantly in PRC transfusion (0.6%), followed by FFP (0.3%), cryoprecipitate (0.1%), and TC (0.1%), respectively. Conclusion. The proportion of ATR in outpatients blood transfusion unit at Cipto Mangunkusumo Hospital was 1.1%. All reported ATR were category 1 in this study. The ATR was predominantly in PRC transfusion.
    Schlagwörter acute transfusion reaction ; blood transfusion ; patient safety ; proportion ; Internal medicine ; RC31-1245
    Thema/Rubrik (Code) 610
    Sprache Bahasa Indonesia
    Erscheinungsdatum 2020-06-01T00:00:00Z
    Verlag Department of Internal Medicine, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo Hospital
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel: The association between mean platelet volume and poor outcome in patients with COVID-19: Systematic review, meta-analysis, and meta-regression.

    Zein, Ahmad Fariz Malvi Zamzam / Sulistiyana, Catur Setiya / Raffaelo, Wilson Matthew / Pranata, Raymond

    Journal of the Intensive Care Society

    2022  Band 24, Heft 3, Seite(n) 299–308

    Abstract: Introduction: This study aims to assess the association between mean platelet volume (MPV) and poor outcome in patients with COVID-19.: Methods: We performed a comprehensive literature search using the PubMed, Embase and Scopus databases with ... ...

    Abstract Introduction: This study aims to assess the association between mean platelet volume (MPV) and poor outcome in patients with COVID-19.
    Methods: We performed a comprehensive literature search using the PubMed, Embase and Scopus databases with keywords "2019-nCoV" OR "SARS-CoV-2" OR "COVID-19" AND "mean platelet volume" OR "MPV" on 8 July 2021. The primary outcome was composite poor outcome, defined as severe COVID-19 or mortality. The pooled effect estimate was reported as mean differences in terms of MPV between the group with and without outcome.
    Results: There were 17 studies which consist of 4549 patients with COVID-19 were included in this study. The incidence of poor outcome was 25% (20%-30%). Mean MPV was found to be higher in the poor outcome group in compare to no poor outcome group (10.3 ± 1.9 fL vs 9.9 ± 1.7 fL). The mean MPV difference between both group was 0.47 fL [95% CI 0.27, 0.67],
    Conclusion: This meta-analysis indicated that increased MPV was associated with severity and mortality in patients with COVID-19. Further research is needed to determine the optimum cut-off point.
    Sprache Englisch
    Erscheinungsdatum 2022-08-26
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2701626-2
    ISSN 1751-1437 ; 1751-1437
    ISSN (online) 1751-1437
    ISSN 1751-1437
    DOI 10.1177/17511437221121234
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: Clinical Gastroenterology and Gastrointestinal Endoscopy Practices during the Coronavirus Disease 2019 Pandemic in Indonesia: An Online Nationwide Survey.

    Zein, Ahmad Fariz Malvi Zamzam / Pribadi, Rabbinu Rangga / Khasanah, Uswatun / Bestari, Muhammad Begawan / Syam, Ari Fahrial

    Clinical endoscopy

    2021  Band 54, Heft 3, Seite(n) 348–355

    Abstract: Background/aims: The coronavirus disease 2019 (COVID-19) pandemic has necessitated modifications to allow the safe practice of clinical gastroenterology and gastrointestinal endoscopy. This study aimed to investigate the characteristics of clinical ... ...

    Abstract Background/aims: The coronavirus disease 2019 (COVID-19) pandemic has necessitated modifications to allow the safe practice of clinical gastroenterology and gastrointestinal endoscopy. This study aimed to investigate the characteristics of clinical gastroenterology and gastrointestinal endoscopy practices during the COVID-19 pandemic in Indonesia.
    Methods: This cross-sectional study enrolled physician members of the Indonesian Society for Digestive Endoscopy. We used an online self-administered questionnaire disseminated via social media. The 32-item survey determined the baseline characteristics of the participants, characteristics of clinical gastroenterology and gastrointestinal endoscopy practices, involvement of the physicians in the management of COVID-19, and overall impact of the pandemic on practice. All collected data were analyzed using descriptive statistics.
    Results: The 200 participants in this study had a median age of 50 (34-76) years. Modifications in clinical gastroenterology practice were frequently reported in the outpatient (95.5%) and inpatient (100%) settings. All participants reported changes in the gastrointestinal endoscopy practice patterns. Of the participants, 86.0% were working in high-risk zones, and several of them reported inadequate protective personal equipment (34.0%). The median overall impact score of the pandemic on practice was 9 (2-10).
    Conclusion: Physicians practicing clinical gastroenterology and gastrointestinal endoscopy in Indonesia work in high-risk settings. Modifications in clinical gastroenterology and gastrointestinal endoscopy practices are prevalent during the COVID-19 pandemic.
    Sprache Englisch
    Erscheinungsdatum 2021-02-18
    Erscheinungsland Korea (South)
    Dokumenttyp Journal Article
    ZDB-ID 2643507-X
    ISSN 2234-2443 ; 2234-2400
    ISSN (online) 2234-2443
    ISSN 2234-2400
    DOI 10.5946/ce.2020.216
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Ivermectin and mortality in patients with COVID-19: A systematic review, meta-analysis, and meta-regression of randomized controlled trials.

    Zein, Ahmad Fariz Malvi Zamzam / Sulistiyana, Catur Setiya / Raffaelo, Wilson Matthew / Pranata, Raymond

    Diabetes & metabolic syndrome

    2021  Band 15, Heft 4, Seite(n) 102186

    Abstract: Aims: This systematic review and meta-analysis aims to investigate the effect of ivermectin on mortality in patients with COVID-19.: Methods: A comprehensive systematic literature search was performed using PubMed, Scopus, Embase, and Clinicaltrials ... ...

    Abstract Aims: This systematic review and meta-analysis aims to investigate the effect of ivermectin on mortality in patients with COVID-19.
    Methods: A comprehensive systematic literature search was performed using PubMed, Scopus, Embase, and Clinicaltrials.gov from the inception of databases up until April 9, 2021. The intervention group was ivermectin and the control group was standard of care or placebo. The primary outcome was mortality reported as risk ratio (RR).
    Results: There were 9 RCTs comprising of 1788 patients included in this meta-analysis. Ivermectin was associated with decreased mortality (RR 0.39 [95% 0.20-0.74], p = 0.004; I
    Conclusions: Ivermectin was associated with decreased mortality in COVID-19 with a low certainty of evidence. Further adequately powered double-blinded placebo-controlled RCTs are required for definite conclusion.
    Mesh-Begriff(e) Antiparasitic Agents/therapeutic use ; COVID-19/drug therapy ; COVID-19/mortality ; COVID-19/virology ; Humans ; Ivermectin/therapeutic use ; Prognosis ; Randomized Controlled Trials as Topic ; SARS-CoV-2/drug effects ; Survival Rate
    Chemische Substanzen Antiparasitic Agents ; Ivermectin (70288-86-7)
    Sprache Englisch
    Erscheinungsdatum 2021-06-27
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 2273766-2
    ISSN 1878-0334 ; 1871-4021
    ISSN (online) 1878-0334
    ISSN 1871-4021
    DOI 10.1016/j.dsx.2021.102186
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Clinical Gastroenterology and Gastrointestinal Endoscopy Practices during the Coronavirus Disease 2019 Pandemic in Indonesia

    Ahmad Fariz Malvi Zamzam Zein / Rabbinu Rangga Pribadi / Uswatun Khasanah / Muhammad Begawan Bestari / Ari Fahrial Syam

    Clinical Endoscopy, Vol 54, Iss 3, Pp 348-

    An Online Nationwide Survey

    2021  Band 355

    Abstract: Background/Aims The coronavirus disease 2019 (COVID-19) pandemic has necessitated modifications to allow the safe practice of clinical gastroenterology and gastrointestinal endoscopy. This study aimed to investigate the characteristics of clinical ... ...

    Abstract Background/Aims The coronavirus disease 2019 (COVID-19) pandemic has necessitated modifications to allow the safe practice of clinical gastroenterology and gastrointestinal endoscopy. This study aimed to investigate the characteristics of clinical gastroenterology and gastrointestinal endoscopy practices during the COVID-19 pandemic in Indonesia. Methods This cross-sectional study enrolled physician members of the Indonesian Society for Digestive Endoscopy. We used an online self-administered questionnaire disseminated via social media. The 32-item survey determined the baseline characteristics of the participants, characteristics of clinical gastroenterology and gastrointestinal endoscopy practices, involvement of the physicians in the management of COVID-19, and overall impact of the pandemic on practice. All collected data were analyzed using descriptive statistics. Results The 200 participants in this study had a median age of 50 (34–76) years. Modifications in clinical gastroenterology practice were frequently reported in the outpatient (95.5%) and inpatient (100%) settings. All participants reported changes in the gastrointestinal endoscopy practice patterns. Of the participants, 86.0% were working in high-risk zones, and several of them reported inadequate protective personal equipment (34.0%). The median overall impact score of the pandemic on practice was 9 (2–10). Conclusions Physicians practicing clinical gastroenterology and gastrointestinal endoscopy in Indonesia work in high-risk settings. Modifications in clinical gastroenterology and gastrointestinal endoscopy practices are prevalent during the COVID-19 pandemic.
    Schlagwörter clinical ; covid-19 ; gastroenterology ; gastrointestinal endoscopy ; practice ; Internal medicine ; RC31-1245 ; Diseases of the digestive system. Gastroenterology ; RC799-869
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2021-05-01T00:00:00Z
    Verlag Hoon Jai Chun
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Artikel ; Online: The Association Between the Pattern of Electronic Cigarette Smoking and Gastroesophageal Reflux

    Ahmad Fariz Malvi Zamzam Zein / Donny Nauphar / Uswatun Khasanah / Tiar M Pratamawati / Rama S Brajawikalpa / Eka Ayuningtyas / Alif Hamzah

    The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, Vol 22, Iss 1, Pp 16-

    2021  Band 20

    Abstract: Background: This study was aimed to investigate the proportion of gastroesophageal reflux (GER) among electronic cigarette (e-cig) smokers and its association with the pattern of e-cig smoking. Method: This cross-sectional study underwent among e-cig ... ...

    Abstract Background: This study was aimed to investigate the proportion of gastroesophageal reflux (GER) among electronic cigarette (e-cig) smokers and its association with the pattern of e-cig smoking. Method: This cross-sectional study underwent among e-cig smokers community in Cirebon City, Jawa Barat, ranged from March to August 2020. Subjects were enrolled through consecutive sampling method. The data collection used survey containing the pattern of e-cig smoking and GER. The pattern of e-cig smoking included the duration of e-cig smoking and the amount of e-cig smoking. Gastroesophageal reflux consisted of GER-related symptoms (heartburn, regurgitation, and nocturnal symptom) and gastroesophageal reflux disease (GERD). GERD was defined as GERD questionnaire score cut-off 8. Data analysis used chi square test. This study has been approved by The Medical Research Ethics Committee, Faculty of Medicine, Universitas Swadaya Gunung Jati. Results: There were 273 respondents in this study. The proportion of heartburn was 6.6%, 10.3% for regurgitation, 3.7% for nocturnal symptom, and 5.5% for GERD. There was no association between duration of e-cig smoking and heartburn (p 0.681), regurgitation (p 0.568), nocturnal symptom (p 0.764), and GERD (p 0.113). There was no association between amount of e-cig smoking and heartburn (p 0.062), regurgitation (p 0.770), nocturnal symptom (p 0.985), and GERD (p 0.605). Conclusion: There was relatively low proportion of GER among e-cig smokers. There was no association between the pattern of e-cig smoking and GER in this study.
    Schlagwörter electronic cigarette smoking ; gastroesophageal reflux ; symptoms ; gastroesophageal reflux disease ; Medicine ; R ; Diseases of the digestive system. Gastroenterology ; RC799-869
    Thema/Rubrik (Code) 616
    Sprache Englisch
    Erscheinungsdatum 2021-05-01T00:00:00Z
    Verlag Interna Publishing
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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