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  1. Article ; Online: Statistics review 14: Logistic regression.

    Bewick, Viv / Cheek, Liz / Ball, Jonathan

    Critical care (London, England)

    2005  Volume 9, Issue 1, Page(s) 112–118

    Abstract: This review introduces logistic regression, which is a method for modelling the dependence of a binary response variable on one or more explanatory variables. Continuous and categorical explanatory variables are considered. ...

    Abstract This review introduces logistic regression, which is a method for modelling the dependence of a binary response variable on one or more explanatory variables. Continuous and categorical explanatory variables are considered.
    MeSH term(s) Humans ; Logistic Models ; Probability
    Language English
    Publishing date 2005-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2051256-9
    ISSN 1466-609X ; 1466-609X
    ISSN (online) 1466-609X
    ISSN 1466-609X
    DOI 10.1186/cc3045
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Statistics review 13: receiver operating characteristic curves.

    Bewick, Viv / Cheek, Liz / Ball, Jonathan

    Critical care (London, England)

    2004  Volume 8, Issue 6, Page(s) 508–512

    Abstract: This review introduces some commonly used methods for assessing the performance of a diagnostic test. The sensitivity, specificity and likelihood ratio of a test are discussed. The uses of the receiver operating characteristic curve and the area under ... ...

    Abstract This review introduces some commonly used methods for assessing the performance of a diagnostic test. The sensitivity, specificity and likelihood ratio of a test are discussed. The uses of the receiver operating characteristic curve and the area under the curve are explained.
    MeSH term(s) Area Under Curve ; Computer Graphics ; Diagnosis ; Humans ; Models, Statistical ; Probability ; ROC Curve ; Sensitivity and Specificity
    Language English
    Publishing date 2004-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2051256-9
    ISSN 1466-609X ; 1466-609X
    ISSN (online) 1466-609X
    ISSN 1466-609X
    DOI 10.1186/cc3000
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Statistics review 10: further nonparametric methods.

    Bewick, Viv / Cheek, Liz / Ball, Jonathan

    Critical care (London, England)

    2004  Volume 8, Issue 3, Page(s) 196–199

    Abstract: This review introduces nonparametric methods for testing differences between more than two groups or treatments. Three of the more common tests are described in detail, together with multiple comparison procedures for identifying specific differences ... ...

    Abstract This review introduces nonparametric methods for testing differences between more than two groups or treatments. Three of the more common tests are described in detail, together with multiple comparison procedures for identifying specific differences between pairs of groups.
    MeSH term(s) Clinical Trials as Topic/methods ; Clinical Trials as Topic/statistics & numerical data ; Data Interpretation, Statistical ; Humans ; Research Design ; Statistics, Nonparametric
    Language English
    Publishing date 2004-04-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/cc2857
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Statistics review 12: survival analysis.

    Bewick, Viv / Cheek, Liz / Ball, Jonathan

    Critical care (London, England)

    2004  Volume 8, Issue 5, Page(s) 389–394

    Abstract: This review introduces methods of analyzing data arising from studies where the response variable is the length of time taken to reach a certain end-point, often death. The Kaplan-Meier methods, log rank test and Cox's proportional hazards model are ... ...

    Abstract This review introduces methods of analyzing data arising from studies where the response variable is the length of time taken to reach a certain end-point, often death. The Kaplan-Meier methods, log rank test and Cox's proportional hazards model are described.
    MeSH term(s) Bias ; Data Interpretation, Statistical ; Endpoint Determination/statistics & numerical data ; Humans ; Linear Models ; Proportional Hazards Models ; Survival Analysis
    Language English
    Publishing date 2004-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2051256-9
    ISSN 1466-609X ; 1466-609X
    ISSN (online) 1466-609X
    ISSN 1466-609X
    DOI 10.1186/cc2955
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Statistics review 9: one-way analysis of variance.

    Bewick, Viv / Cheek, Liz / Ball, Jonathan

    Critical care (London, England)

    2004  Volume 8, Issue 2, Page(s) 130–136

    Abstract: This review introduces one-way analysis of variance, which is a method of testing differences between more than two groups or treatments. Multiple comparison procedures and orthogonal contrasts are described as methods for identifying specific ... ...

    Abstract This review introduces one-way analysis of variance, which is a method of testing differences between more than two groups or treatments. Multiple comparison procedures and orthogonal contrasts are described as methods for identifying specific differences between pairs of treatments.
    MeSH term(s) Analysis of Variance ; Clinical Trials as Topic/methods ; Clinical Trials as Topic/statistics & numerical data ; Data Interpretation, Statistical ; Humans ; Models, Statistical ; Research Design
    Language English
    Publishing date 2004-04
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2051256-9
    ISSN 1466-609X ; 1466-609X
    ISSN (online) 1466-609X
    ISSN 1466-609X
    DOI 10.1186/cc2836
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Statistics review 8: Qualitative data - tests of association.

    Bewick, Viv / Cheek, Liz / Ball, Jonathan

    Critical care (London, England)

    2004  Volume 8, Issue 1, Page(s) 46–53

    Abstract: This review introduces methods for investigating relationships between two qualitative (categorical) variables. The chi2 test of association is described, together with the modifications needed for small samples. The test for trend, in which at least one ...

    Abstract This review introduces methods for investigating relationships between two qualitative (categorical) variables. The chi2 test of association is described, together with the modifications needed for small samples. The test for trend, in which at least one of the variables is ordinal, is also outlined. Risk measurement is discussed. The calculation of confidence intervals for proportions and differences between proportions are described. Situations in which samples are matched are considered.
    MeSH term(s) Chi-Square Distribution ; Clinical Trials as Topic ; Confidence Intervals ; Data Interpretation, Statistical ; Evaluation Studies as Topic ; Matched-Pair Analysis ; Odds Ratio ; United Kingdom
    Language English
    Publishing date 2004-02
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2051256-9
    ISSN 1466-609X ; 1466-609X
    ISSN (online) 1466-609X
    ISSN 1466-609X
    DOI 10.1186/cc2428
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Statistics review 7: Correlation and regression.

    Bewick, Viv / Cheek, Liz / Ball, Jonathan

    Critical care (London, England)

    2003  Volume 7, Issue 6, Page(s) 451–459

    Abstract: The present review introduces methods of analyzing the relationship between two quantitative variables. The calculation and interpretation of the sample product moment correlation coefficient and the linear regression equation are discussed and ... ...

    Abstract The present review introduces methods of analyzing the relationship between two quantitative variables. The calculation and interpretation of the sample product moment correlation coefficient and the linear regression equation are discussed and illustrated. Common misuses of the techniques are considered. Tests and confidence intervals for the population parameters are described, and failures of the underlying assumptions are highlighted.
    MeSH term(s) Analysis of Variance ; Confidence Intervals ; Linear Models
    Language English
    Publishing date 2003-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041406-7
    ISSN 1364-8535
    ISSN 1364-8535
    DOI 10.1186/cc2401
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Statistics review 11: assessing risk.

    Bewick, Viv / Cheek, Liz / Ball, Jonathan

    Critical care (London, England)

    2004  Volume 8, Issue 4, Page(s) 287–291

    Abstract: Relative risk and odds ratio have been introduced in earlier reviews (see Statistics reviews 3, 6 and 8). This review describes the calculation and interpretation of their confidence intervals. The different circumstances in which the use of either the ... ...

    Abstract Relative risk and odds ratio have been introduced in earlier reviews (see Statistics reviews 3, 6 and 8). This review describes the calculation and interpretation of their confidence intervals. The different circumstances in which the use of either the relative risk or odds ratio is appropriate and their relative merits are discussed. A method of measuring the impact of exposure to a risk factor is introduced. Measures of the success of a treatment using data from clinical trials are also considered.
    MeSH term(s) Alleles ; Clinical Trials as Topic ; Confidence Intervals ; Evidence-Based Medicine/methods ; Evidence-Based Medicine/statistics & numerical data ; Humans ; Odds Ratio ; Protein Precursors/genetics ; Proteolipids/genetics ; Respiratory Distress Syndrome, Adult/genetics ; Risk Assessment/methods ; Risk Assessment/statistics & numerical data ; Risk Factors
    Chemical Substances Protein Precursors ; Proteolipids ; surfactant protein B propeptide
    Language English
    Publishing date 2004-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2051256-9
    ISSN 1466-609X ; 1466-609X
    ISSN (online) 1466-609X
    ISSN 1466-609X
    DOI 10.1186/cc2908
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Identifying the patient at risk of acute kidney injury: a predictive scoring system for the development of acute kidney injury in acute medical patients.

    Forni, Lui G / Dawes, Thomas / Sinclair, Hamish / Cheek, Elizabeth / Bewick, Vivien / Dennis, Mark / Venn, Richard

    Nephron. Clinical practice

    2013  Volume 123, Issue 3-4, Page(s) 143–150

    Abstract: Background: Acute kidney injury (AKI) in hospitalized patients has significant implications in terms of morbidity and mortality, length of hospital stay and associated costs. To date, no interventions are proven to prevent the development of AKI but ... ...

    Abstract Background: Acute kidney injury (AKI) in hospitalized patients has significant implications in terms of morbidity and mortality, length of hospital stay and associated costs. To date, no interventions are proven to prevent the development of AKI but this is hampered in part by the lack of early recognition of patients at risk. We aimed to determine whether a simple system could be devised from both physiological and demographic data in order to identify individuals at increased risk from the development of inpatient AKI.
    Method: Our observational, population-based single-centred study took place in an 870-bed associated university hospital. All patients admitted to the acute medical admissions unit on the Worthing site of the Western Sussex Hospitals Trust during the study period were included.
    Results: Multivariate logistic regression analysis demonstrated that age, respiratory rate and disturbed consciousness together with a history of chronic kidney disease, diabetes mellitus, congestive cardiac failure and liver disease were associated with an increased risk of developing AKI within 7 days of admission. We derived a simple scoring system to identify acute medical patients at greater risk of developing AKI.
    Conclusions: The incidence of AKI complicating inpatient admissions remains high, however with the application of the derived AKI prediction score it is hoped that early recognition will translate to improved outcomes.
    MeSH term(s) Acute Kidney Injury/etiology ; Aged ; Aged, 80 and over ; Female ; Humans ; Logistic Models ; Male ; Middle Aged ; Prospective Studies ; Risk
    Language English
    Publishing date 2013
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 207121-6
    ISSN 1660-2110 ; 1423-0186 ; 2235-3186 ; 1660-8151 ; 0028-2766
    ISSN (online) 1660-2110 ; 1423-0186 ; 2235-3186
    ISSN 1660-8151 ; 0028-2766
    DOI 10.1159/000351509
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Identifying the Patient at Risk of Acute Kidney Injury: A Predictive Scoring System for the Development of Acute Kidney Injury in Acute Medical Patients

    Forni, Lui G. / Dawes, Thomas / Sinclair, Hamish / Cheek, Elizabeth / Bewick, Vivien / Dennis, Mark / Venn, Richard

    Nephron Clinical Practice

    2013  Volume 123, Issue 3-4, Page(s) 143–150

    Abstract: Background: Acute kidney injury (AKI) in hospitalized patients has significant implications in terms of morbidity and mortality, length of hospital stay and associated costs. To date, no interventions are proven to prevent the development of AKI but this ...

    Institution Department of Critical Care, Worthing Hospital, and Department of Performance and Information, Western Sussex Hospitals Trust, Worthing, and School of Computing, Mathematical and Information Sciences, University of Brighton, Brighton, UK
    Abstract Background: Acute kidney injury (AKI) in hospitalized patients has significant implications in terms of morbidity and mortality, length of hospital stay and associated costs. To date, no interventions are proven to prevent the development of AKI but this is hampered in part by the lack of early recognition of patients at risk. We aimed to determine whether a simple system could be devised from both physiological and demographic data in order to identify individuals at increased risk from the development of inpatient AKI. Method: Our observational, population-based single-centred study took place in an 870-bed associated university hospital. All patients admitted to the acute medical admissions unit on the Worthing site of the Western Sussex Hospitals Trust during the study period were included. Results: Multivariate logistic regression analysis demonstrated that age, respiratory rate and disturbed consciousness together with a history of chronic kidney disease, diabetes mellitus, congestive cardiac failure and liver disease were associated with an increased risk of developing AKI within 7 days of admission. We derived a simple scoring system to identify acute medical patients at greater risk of developing AKI. Conclusions: The incidence of AKI complicating inpatient admissions remains high, however with the application of the derived AKI prediction score it is hoped that early recognition will translate to improved outcomes.
    Keywords Acute kidney injury ; Scoring systems ; Acute medical admissions
    Language English
    Publishing date 2013-07-25
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Original Paper
    ZDB-ID 207121-6
    ISSN 1660-2110 ; 1423-0186 ; 2235-3186 ; 1660-8151 ; 0028-2766
    ISSN (online) 1660-2110 ; 1423-0186 ; 2235-3186
    ISSN 1660-8151 ; 0028-2766
    DOI 10.1159/000351509
    Database Karger publisher's database

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