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  1. Book ; Thesis: Kontinenzerhalt nach radikaler Prostatektomie in der Versorgungswirklichkeit

    Briel, Christoph Matthias Emanuel / Lent, Volkmar / Pförtner, Timo-Kolja

    2021  

    Institution Universitätsklinikum Köln / Klinik für Urologie, Uro-Onkologie, Spezielle Urologische und Roboter-Assistierte Chirurgie
    Author's details vorgelegt von Christoph Matthias Emanuel Briel ; 1. Gutachter: Professor Dr. med. V. Lent, 2. Gutachter: Privatdozent Dr. rer. pol. T.-K. Pförtner ; aus der Klinik für Urologie, Uro-Onkologie, spezielle urologische und roboter-asisstierte Chirurgie der Universität zu Köln
    Subject code 610
    Language German
    Size 52 Seiten, Diagramme
    Publishing place Köln
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität zu Köln, 2020
    HBZ-ID HT020876864
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2021 D 193 order for loan Magazin

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  2. Article ; Online: A call for error management in academic clinical research.

    McLennan, Stuart / Briel, Matthias

    Journal of clinical epidemiology

    2022  Volume 154, Page(s) 208–211

    Language English
    Publishing date 2022-12-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639306-8
    ISSN 1878-5921 ; 0895-4356
    ISSN (online) 1878-5921
    ISSN 0895-4356
    DOI 10.1016/j.jclinepi.2022.11.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh III Zs.206: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Guidance needed: where should randomized studies which do not assess a health outcome be registered?

    Speich, Benjamin / Schroter, Sara / Briel, Matthias

    Journal of clinical epidemiology

    2023  Volume 161, Page(s) 183–184

    MeSH term(s) Humans ; Registries ; Outcome Assessment, Health Care ; Treatment Outcome
    Language English
    Publishing date 2023-07-31
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 639306-8
    ISSN 1878-5921 ; 0895-4356
    ISSN (online) 1878-5921
    ISSN 0895-4356
    DOI 10.1016/j.jclinepi.2023.07.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh III Zs.206: Show issues Location:
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  4. Article ; Online: Searching a methods topic: practical challenges and implications for search design.

    Hirt, Julian / Ewald, Hannah / Briel, Matthias / Schandelmaier, Stefan

    Journal of clinical epidemiology

    2023  Volume 166, Page(s) 111201

    MeSH term(s) Humans ; Search Engine ; Information Storage and Retrieval ; Databases, Bibliographic
    Language English
    Publishing date 2023-10-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639306-8
    ISSN 1878-5921 ; 0895-4356
    ISSN (online) 1878-5921
    ISSN 0895-4356
    DOI 10.1016/j.jclinepi.2023.10.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.206: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Book ; Thesis: Untersuchungen zur Regulation des epithelialen Na+-Kanals durch CFTR

    Briel, Matthias

    2000  

    Author's details vorgelegt von Matthias Briel
    Language German
    Size 48 Bl., graph. Darst.
    Edition [Mikrofiche-Ausg.]
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Freiburg (Breisgau), Univ., Diss., 2000
    HBZ-ID HT013117989
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2001 MB 1216 order for loan Magazin

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  6. Conference proceedings: LIbrary of Guidance for HealTh Scientists (LIGHTS): an open-access inventory for methods guidance

    Hirt, Julian / Briel, Matthias / Schandelmaier, Stefan

    2023  , Page(s) 23ebmPSII–3–07

    Event/congress 24. Jahrestagung des Netzwerks Evidenzbasierte Medizin; Gesundheit und Klima – EbM für die Zukunft; Potsdam; Netzwerk Evidenzbasierte Medizin e.V.; 2023
    Keywords Medizin, Gesundheit
    Publishing date 2023-03-21
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/23ebm072
    Database German Medical Science

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  7. Article ; Online: Digital tools for trial recruitment and retention-plenty of tools but rigorous evaluation is in short supply.

    Treweek, Shaun / Briel, Matthias

    Trials

    2020  Volume 21, Issue 1, Page(s) 476

    MeSH term(s) Clinical Trials as Topic ; Humans ; Patient Selection ; Research Personnel ; Social Media ; Surveys and Questionnaires ; Telephone
    Language English
    Publishing date 2020-06-05
    Publishing country England
    Document type Editorial
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1468-6708
    ISSN (online) 1745-6215 ; 1468-6694
    ISSN 1468-6708
    DOI 10.1186/s13063-020-04361-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Digital tools for trial recruitment and retention—plenty of tools but rigorous evaluation is in short supply

    Shaun Treweek / Matthias Briel

    Trials, Vol 21, Iss 1, Pp 1-

    2020  Volume 2

    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Practices and Attitudes of Swiss Stakeholders Regarding Investigator-Initiated Clinical Trial Funding Acquisition and Cost Management.

    McLennan, Stuart / Griessbach, Alexandra / Briel, Matthias

    JAMA network open

    2021  Volume 4, Issue 6, Page(s) e2111847

    Abstract: Importance: Randomized clinical trials (RCTs) are an essential method of evaluating health care interventions and a cornerstone for evidence-based health care. However, RCTs have become increasingly complex and costly, which is particularly challenging ... ...

    Abstract Importance: Randomized clinical trials (RCTs) are an essential method of evaluating health care interventions and a cornerstone for evidence-based health care. However, RCTs have become increasingly complex and costly, which is particularly challenging for independent investigator-initiated clinical trials (IICTs). IICTs have an essential role in clinical research, and it is important that efforts are made to ensure IICTs are adequately funded and are conducted cost-effectively.
    Objective: To examine the practices and attitudes of Swiss stakeholders regarding IICT funding acquisition and cost management.
    Design, setting, and participants: For this qualitative study, interviews were conducted in Switzerland between February and August 2020. The purposive sample comprised 48 stakeholders from 4 different groups: primary investigators (n = 27), funders and sponsors (n = 9), clinical trial support organizations (n = 6), and ethics committee members (n = 6).
    Main outcomes and measures: Practices and attitudes of stakeholders regarding IICT funding acquisition and cost management were assessed using individual semistructured qualitative interviews. Interviews were analyzed using conventional content analysis.
    Results: After interviews with 48 IICT stakeholders (75% male presenting), these participants identified a systemic problem of IICTs being underfunded, which can lead to compromises being made regarding the quality and conduct of IICTs. Participants identified 2 overarching and interconnected groups of reasons why IICTs in Switzerland are regularly underfunded. First, it was reported that IICT budget estimations are often inaccurate because of poor planning and preparation, unforeseeable events, investigators intentionally underestimating budgets, and limited budget assessment and oversight. Second, with the exception of a specific IICT funding program by the Swiss National Science Foundation, it was reported that limited funding sources and unrealistic expectation of funders led to underlying challenges in getting IICTs fully funded. A number of measures that could help reduce the underfunding of IICTs were identified, including improving the support of investigators and IICTs, strengthening networking and guidance, harmonizing and simplifying bureaucracy, and increasing public funding of IICTs.
    Conclusions and relevance: This study highlights the inadequate expertise of Swiss stakeholders to correctly, systematically, and reproducibly calculate RCT budgets and the need for transparency on trial costs as well as training in budgeting practices. Limited financial resources for academic clinical research and issues regarding the professional planning and conduct of IICTs are persistent issues that many other countries also face.
    MeSH term(s) Adult ; Attitude of Health Personnel ; Biomedical Research/organization & administration ; Clinical Trials as Topic/standards ; Female ; Humans ; Male ; Outcome and Process Assessment, Health Care ; Research Personnel/standards ; Stakeholder Participation ; Switzerland
    Language English
    Publishing date 2021-06-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2021.11847
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Library of Guidance for Health Scientists (LIGHTS): Eine neue Datenbank für methodische Leitlinien in der klinischen Forschung

    Hirt, Julian / Ewald, Hannah / Briel, Matthias / Schandelmaier, Stefan

    GMS Medizin - Bibliothek - Information

    2022  Volume 22, Issue 2, Page(s) 28

    Abstract: Methodische Probleme (z.B. Umgang mit fehlenden Daten, irrelevante Endpunkte, fehlerhafte Subgruppenanalysen) begrenzen häufig den wissenschaftlichen Wert von klinischen Studien. Zu den Versäumnissen trägt bei, dass Gesundheitsforschende relevante ... ...

    Title translation Library of Guidance for Health Scientists (LIGHTS): A new database for methods guidance in clinical research
    Abstract Methodische Probleme (z.B. Umgang mit fehlenden Daten, irrelevante Endpunkte, fehlerhafte Subgruppenanalysen) begrenzen häufig den wissenschaftlichen Wert von klinischen Studien. Zu den Versäumnissen trägt bei, dass Gesundheitsforschende relevante Methodenleitlinien nicht finden können. Um die Auffindbarkeit von Methodenleitlinien zu verbessern, haben wir die Library of Guidance for Health Scientists (LIGHTS, https://lights.science/) entwickelt. LIGHTS ist eine neue, frei zugängliche Datenbank zur effektiven Unterstützung von klinisch Forschenden, StatistikerInnen, Methodenberatungen, Ethikkommissionen, Peer-Reviews, Herausgebenden von Zeitschriften, Forschungsförderern und anderen, die nach optimalen Methoden in der klinischen Forschung streben.

    Methodological issues (e.g., ignoring missing data, irrelevant outcomes, flawed subgroup analyses) often limit the value of health research. One reason is that health researchers cannot easily find relevant methods guidance. To improve the findability of methods guidance, we initiated the development of the Library of Guidance for Health Scientists (LIGHTS, https://lights.science/). LIGHTS is a new open access database to effectively support health researchers, statisticians, methods consultants, methods developers, ethics boards, peer reviewers, journal editors, funding bodies, and others who are searching for optimal methods guidance in clinical research.
    Keywords Medizin, Gesundheit ; database ; guidelines as topic ; methods ; methods guidance ; reporting quality ; transparency ; Datenbank ; Leitlinien ; Methoden ; methodische Leitlinien ; Berichterstattungsqualität ; Transparenz ; Leuchtturmprojekte
    Publishing date 2022-12-20
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Article ; Online
    ISSN 1865-066X
    ISSN (online) 1865-066X
    DOI 10.3205/mbi000546
    Database German Medical Science

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