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Article ; Online: Accidental poisoning in children: a single centre case series study in Bangladesh.

Ahmed, Ahsan / Hasanul Banna Siam, Md / Shojon, Mohammad / Mahdi Hasan, Md / Raheem, Enayetur / Hossain, Mohammad Sorowar

BMJ paediatrics open

2022 Volume 6, Issue 1

Abstract: Background: Accidental poisoning is a leading cause of unintentional injuries among children in low-income and middle-income countries (LMICs). The overall aspect of this unintentional poisoning is poorly understood in Bangladesh. The objectives of this ...

Abstract	Background: Accidental poisoning is a leading cause of unintentional injuries among children in low-income and middle-income countries (LMICs). The overall aspect of this unintentional poisoning is poorly understood in Bangladesh. The objectives of this study were (1) to explore the socio-demographic factors and circumstantial context of accidental poisoning and (2) the prevalence of the type of substances causing it. Methods: A descriptive case series study was conducted from April 2019 to February 2020 at a tertiary level hospital of the capital city Dhaka in Bangladesh. Children under 10 years of age admitted to the hospital with accidental poisoning were enrolled in this study. Parents of hospitalised children were interviewed face-to-face using a structured questionnaire. Descriptive statistics were used for data analysis. Results: A total of 223 children were recruited in this study. Children between 2 and 5 years (60%), men (61%) and children with agility (65.5%) were among the prevalent victims. The majority of cases occurred (65%) in a nuclear family setting. Most mothers (85%) of these children were non-working and most incidents took place in parents' homes (~82%). Nearly 70% of the poisoning incidents took place in the presence of parents and over half of these occurred in the bedroom. Kerosene was the prevalent cause (33%) of accidental poisoning while insecticide/pesticide ranked second (26.5%) followed by medicines (17%) and household chemicals (12). In one-third (31.4%) of the cases, poisoning chemicals were stored in soft drink bottles while two-thirds (67.3%) of the cases were kept in containers other than original ones. Although over 80 parents somewhat knew that chemicals could be harmful to the children if ingested, most of them did not take the safety measures. Conclusion: In this present study we found that preschool-aged children were more victims of accidental poisoning mostly by ingesting kerosene and a majority of the incidents took place in the bedroom while parents were present at home. Our study findings would serve as a baseline for designing future intervention studies and policies.
MeSH term(s)	Accidental Injuries ; Bangladesh/epidemiology ; Child ; Child, Preschool ; Female ; Hospitalization ; Humans ; Kerosene ; Male ; Pesticides
Chemical Substances	Kerosene ; Pesticides
Language	English
Publishing date	2022-07-20
Publishing country	England
Document type	Journal Article
ISSN	2399-9772
ISSN (online)	2399-9772
DOI	10.1136/bmjpo-2022-001541
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Knowledge, attitude, and practice towards blood donation among residential students and teachers of religious institutions in Bangladesh - A cross-sectional study.

Hossain, Mohammad Sorowar / Siam, Md Hasanul Banna / Hasan, Mohammad Nayeem / Jahan, Rifat / Siddiqee, Mahbubul H

Heliyon

2022 Volume 8, Issue 10, Page(s) e10792

Abstract: The availability of voluntary nonremunerated blood donors is a major concern in low- and middle-income countries because there is a substantial scarcity of safe blood supply against the expected demand. This study explores the status of knowledge, ... ...

Abstract	The availability of voluntary nonremunerated blood donors is a major concern in low- and middle-income countries because there is a substantial scarcity of safe blood supply against the expected demand. This study explores the status of knowledge, attitude, and practice regarding blood donation among students and teachers of residential religious academic institutions in Jamalpur district in Bangladesh. Religious institutions were selected through simple random sampling, and the cross-sectional survey included 512 participants. Descriptive and inferential statistics were performed with statistical significance defined as p < 0.05. Over 90% of the participants were students, non-smokers, and aged 18-30 years. The majority (92%) did not ever donate blood to anyone, yet over 42% wanted to be regular donors. More than 80% considered blood donation a moral responsibility and an Islamic act. The common reasons for not donating blood were lack of knowledge (40%), lack of opportunity (20%), thinking it was harmful to health (21%), fearing needles (16%), and no financial benefit (6%). Interestingly, more than 67% did not know their blood group, and about 61% of the respondents said they did not hear of or could not remember any blood donation program. The participants had poor knowledge of general eligibility criteria but an overall positive attitude towards blood donation. There was a weak positive correlation between knowledge, attitude, and practice scores. Participants willing to donate blood to strangers were four times more likely to do so regularly. Those who considered blood donation a religious act and a moral responsibility were twice as likely to become regular blood donors. This study reveals that many potential donors are being neglected, although they may be a valuable resource in addressing the ongoing blood donation issue.
Language	English
Publishing date	2022-09-29
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2022.e10792
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Stopping the COVID-19 Pandemic: A Review on the Advances of Diagnosis, Treatment, and Control Measures.

Siam, Md Hasanul Banna / Nishat, Nahida Hannan / Ahmed, Ahsan / Hossain, Mohammad Sorowar

Journal of pathogens

2020 Volume 2020, Page(s) 9121429

Abstract: With the continued spread of COVID-19 across the world, rapid diagnostic tools, readily available respurposable drugs, and prompt containment measures to control the SARS-CoV-2 infection are of paramount importance. Examples of recent advances in ... ...

Abstract	With the continued spread of COVID-19 across the world, rapid diagnostic tools, readily available respurposable drugs, and prompt containment measures to control the SARS-CoV-2 infection are of paramount importance. Examples of recent advances in diagnostic tests are CRISPR technology, IgG assay, spike protein detection, and use of artificial intelligence. The gold standard reverse transcription polymerase chain (RT-PCR) has also been upgraded with point-of-care rapid tests. Supportive treatment, mechanical ventilation, and extracorporeal membrane oxygenation (ECMO) remain the primary choice, while therapeutic options include antivirals, antiparasitics, anti-inflammatories, interferon, convalescent plasma, monoclonal antibody, hyperimmunoglobulin, RNAi, and mesenchymal stem cell therapy. Different types of vaccines such as RNA, DNA, and lentiviral, inactivated, and viral vector are in clinical trials. Moreover, rapidly deployable and easy-to-transport innovative vaccine delivery systems are also in development. As countries have started easing down on the lockdown measures, the chance for a second wave of infection demands strict and rational control policies to keep fatalities minimized. An improved understanding of the advances in diagnostic tools, treatments, vaccines, and control measures for COVID-19 can provide references for further research and aid better containment strategies.
Keywords	covid19
Language	English
Publishing date	2020-10-18
Publishing country	Egypt
Document type	Journal Article ; Review
ZDB-ID	2662334-1
ISSN	2090-3065 ; 2090-3057
ISSN (online)	2090-3065
ISSN	2090-3057
DOI	10.1155/2020/9121429
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Article ; Online: Knowledge, attitude, and practice towards blood donation among residential students and teachers of religious institutions in Bangladesh – A cross-sectional study

Mohammad Sorowar Hossain / Md. Hasanul Banna Siam / Mohammad Nayeem Hasan / Rifat Jahan / Mahbubul H. Siddiqee

Heliyon, Vol 8, Iss 10, Pp e10792- (2022)

2022

Abstract	The availability of voluntary nonremunerated blood donors is a major concern in low- and middle-income countries because there is a substantial scarcity of safe blood supply against the expected demand. This study explores the status of knowledge, attitude, and practice regarding blood donation among students and teachers of residential religious academic institutions in Jamalpur district in Bangladesh. Religious institutions were selected through simple random sampling, and the cross-sectional survey included 512 participants. Descriptive and inferential statistics were performed with statistical significance defined as p < 0.05. Over 90% of the participants were students, non-smokers, and aged 18–30 years. The majority (92%) did not ever donate blood to anyone, yet over 42% wanted to be regular donors. More than 80% considered blood donation a moral responsibility and an Islamic act. The common reasons for not donating blood were lack of knowledge (40%), lack of opportunity (20%), thinking it was harmful to health (21%), fearing needles (16%), and no financial benefit (6%). Interestingly, more than 67% did not know their blood group, and about 61% of the respondents said they did not hear of or could not remember any blood donation program. The participants had poor knowledge of general eligibility criteria but an overall positive attitude towards blood donation. There was a weak positive correlation between knowledge, attitude, and practice scores. Participants willing to donate blood to strangers were four times more likely to do so regularly. Those who considered blood donation a religious act and a moral responsibility were twice as likely to become regular blood donors. This study reveals that many potential donors are being neglected, although they may be a valuable resource in addressing the ongoing blood donation issue.
Keywords	Voluntary nonremunerated blood donors ; Blood donation ; Blood ; Bangladesh ; Religious motivation ; Religious institute ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Subject code	230
Language	English
Publishing date	2022-10-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Knowledge, attitude, and practice towards blood donation among residential students and teachers of religious institutions in Bangladesh - A cross-sectional study

Hossain, Mohammad Sorowar / Siam, Md. Hasanul Banna / Hasan, Mohammad Nayeem / Jahan, Rifat / Siddiqee, Mahbubul H.

Heliyon. 2022 Oct., v. 8, no. 10 p.e10792-

2022

Abstract	The availability of voluntary nonremunerated blood donors is a major concern in low- and middle-income countries because there is a substantial scarcity of safe blood supply against the expected demand. This study explores the status of knowledge, attitude, and practice regarding blood donation among students and teachers of residential religious academic institutions in Jamalpur district in Bangladesh. Religious institutions were selected through simple random sampling, and the cross-sectional survey included 512 participants. Descriptive and inferential statistics were performed with statistical significance defined as p < 0.05. Over 90% of the participants were students, non-smokers, and aged 18-30 years. The majority (92%) did not ever donate blood to anyone, yet over 42% wanted to be regular donors. More than 80% considered blood donation a moral responsibility and an Islamic act. The common reasons for not donating blood were lack of knowledge (40%), lack of opportunity (20%), thinking it was harmful to health (21%), fearing needles (16%), and no financial benefit (6%). Interestingly, more than 67% did not know their blood group, and about 61% of the respondents said they did not hear of or could not remember any blood donation program. The participants had poor knowledge of general eligibility criteria but an overall positive attitude towards blood donation. There was a weak positive correlation between knowledge, attitude, and practice scores. Participants willing to donate blood to strangers were four times more likely to do so regularly. Those who considered blood donation a religious act and a moral responsibility were twice as likely to become regular blood donors. This study reveals that many potential donors are being neglected, although they may be a valuable resource in addressing the ongoing blood donation issue.
Keywords	blood ; blood groups ; cross-sectional studies ; statistics ; Bangladesh ; Voluntary nonremunerated blood donors ; Blood donation ; Religious motivation ; Religious institute ; Transfusion ; Community
Language	English
Dates of publication	2022-10
Publishing place	Elsevier Ltd
Document type	Article ; Online
Note	Use and reproduction
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2022.e10792
Database	NAL-Catalogue (AGRICOLA)

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Article: Insights into the first seven-months of COVID-19 pandemic in Bangladesh: lessons learned from a high-risk country.

Siam, Md Hasanul Banna / Hasan, Md Mahbub / Tashrif, Shazed Mohammad / Rahaman Khan, Md Hasinur / Raheem, Enayetur / Hossain, Mohammad Sorowar

Heliyon

2021 Volume 7, Issue 6, Page(s) e07385

Abstract: South Asian countries have been struggling to control the COVID-19 pandemic despite imposing months of lockdown and other public health measures. This review aims to describe the epidemiological features and shortcomings in public health preparedness to ... ...

Abstract	South Asian countries have been struggling to control the COVID-19 pandemic despite imposing months of lockdown and other public health measures. This review aims to describe the epidemiological features and shortcomings in public health preparedness to tackle COVID-19 as well as derive lessons from these events in the context of Bangladesh. We have shown that an increase in human mobility was evident throughout the lockdown period. Over 20,000 frontline health workers were affected, and more than 2100 unofficial deaths possibly linked with COVID-19 diagnosis were reported. Males were disproportionately affected in terms of infection (71%) and death (77%) than females. Over 50% of infected cases were reported among young adults (20-40-year age group). After seven months into the pandemic, a downward trend in laboratory test positive percentage was seen, although the number of new deaths per day remained largely unchanged. We believe our findings, observations and recommendations will remain as a valuable resource to facilitate better public health practice and policy for managing current and future infectious disease like COVID-19 in resource-poor developing countries.
Language	English
Publishing date	2021-06-25
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2021.e07385
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Insights into the first seven-months of COVID-19 pandemic in Bangladesh

Md. Hasanul Banna Siam / Md. Mahbub Hasan / Shazed Mohammad Tashrif / Md Hasinur Rahaman Khan / Enayetur Raheem / Mohammad Sorowar Hossain

Heliyon, Vol 7, Iss 6, Pp e07385- (2021)

lessons learned from a high-risk country

2021

Abstract	South Asian countries have been struggling to control the COVID-19 pandemic despite imposing months of lockdown and other public health measures. This review aims to describe the epidemiological features and shortcomings in public health preparedness to tackle COVID-19 as well as derive lessons from these events in the context of Bangladesh. We have shown that an increase in human mobility was evident throughout the lockdown period. Over 20,000 frontline health workers were affected, and more than 2100 unofficial deaths possibly linked with COVID-19 diagnosis were reported. Males were disproportionately affected in terms of infection (71%) and death (77%) than females. Over 50% of infected cases were reported among young adults (20-40-year age group). After seven months into the pandemic, a downward trend in laboratory test positive percentage was seen, although the number of new deaths per day remained largely unchanged. We believe our findings, observations and recommendations will remain as a valuable resource to facilitate better public health practice and policy for managing current and future infectious disease like COVID-19 in resource-poor developing countries.
Keywords	COVID-19 ; Pandemic ; Bangladesh ; Dhaka ; Epidemiology ; SARS-CoV2 ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Subject code	360
Language	English
Publishing date	2021-06-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Stopping the COVID-19 Pandemic: A Review on the Advances of Diagnosis, Treatment, and Control Measures

Siam, Md. Hasanul Banna / Nishat, Nahida Hannan / Ahmed, Ahsan / Hossain, Mohammad Sorowar

Journal of pathogens. 2020 Oct. 18, v. 2020

2020

Abstract	With the continued spread of COVID-19 across the world, rapid diagnostic tools, readily available respurposable drugs, and prompt containment measures to control the SARS-CoV-2 infection are of paramount importance. Examples of recent advances in diagnostic tests are CRISPR technology, IgG assay, spike protein detection, and use of artificial intelligence. The gold standard reverse transcription polymerase chain (RT-PCR) has also been upgraded with point-of-care rapid tests. Supportive treatment, mechanical ventilation, and extracorporeal membrane oxygenation (ECMO) remain the primary choice, while therapeutic options include antivirals, antiparasitics, anti-inflammatories, interferon, convalescent plasma, monoclonal antibody, hyperimmunoglobulin, RNAi, and mesenchymal stem cell therapy. Different types of vaccines such as RNA, DNA, and lentiviral, inactivated, and viral vector are in clinical trials. Moreover, rapidly deployable and easy-to-transport innovative vaccine delivery systems are also in development. As countries have started easing down on the lockdown measures, the chance for a second wave of infection demands strict and rational control policies to keep fatalities minimized. An improved understanding of the advances in diagnostic tools, treatments, vaccines, and control measures for COVID-19 can provide references for further research and aid better containment strategies.
Keywords	COVID-19 infection ; DNA ; RNA ; RNA interference ; Severe acute respiratory syndrome coronavirus 2 ; antiparasitic agents ; antiviral agents ; artificial intelligence ; clinical trials ; control methods ; death ; diagnostic techniques ; gene editing ; immunoglobulin G ; interferons ; issues and policy ; mesenchymal stromal cells ; monoclonal antibodies ; pathogens ; point-of-care systems ; rapid methods ; reverse transcriptase polymerase chain reaction ; therapeutics ; vaccines
Language	English
Dates of publication	2020-1018
Publishing place	Hindawi
Document type	Article
ZDB-ID	2662334-1
ISSN	2090-3065 ; 2090-3057
ISSN (online)	2090-3065
ISSN	2090-3057
DOI	10.1155/2020/9121429
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: In silico insights into potential gut microbial modulation of NAD+ metabolism and longevity.

Salekeen, Rahagir / Siam, Md Hasanul Banna / Sharif, Dilara Islam / Lustgarten, Michael S / Billah, Md Morsaline / Islam, Kazi Mohammed Didarul

Journal of biochemical and molecular toxicology

2021 Volume 35, Issue 12, Page(s) e22925

Abstract: Recent evidence has prompted the notion of gut-microbial signatures as an indirect marker of aging and aging-associated decline in humans. However, the underlying host-symbiont molecular interactions contributing to these signatures remain poorly ... ...

Abstract	Recent evidence has prompted the notion of gut-microbial signatures as an indirect marker of aging and aging-associated decline in humans. However, the underlying host-symbiont molecular interactions contributing to these signatures remain poorly understood. In this study, we address this gap using cheminformatic analyses to elucidate potential gut microbial metabolites that may perturb the longevity-associated NAD+ metabolic network. In silico ADMET, KEGG interaction analysis, molecular docking, molecular dynamics simulation, and molecular mechanics calculation predict a large number of safe and bioavailable microbial metabolites to be direct and/or indirect activators of NAD+-dependent sirtuin proteins. Our simulation results suggest dihydropteroate, phenylpyruvic acid, indole-3-propionic acid, phenyllactic acid, all-trans-retinoic acid, and multiple deoxy-, methyl-, and cyclic nucleotides from intestinal microbiota as the best-performing regulators of NAD+ metabolism. Retracing these molecules to their source microorganisms also suggest commensal Escherichia, Bacteroides, Bifidobacteria, and Lactobacilli to be associated with the highest number of pro-longevity metabolites. These findings from our early-stage study, therefore, provide an informatics-based context for previous evidence in the area and grant novel insights for future clinical investigation intersecting anti-aging drug discovery, probiotics, and gut microbial signatures.
MeSH term(s)	Algorithms ; Computer Simulation ; Gastrointestinal Microbiome ; Humans ; Ligands ; Longevity ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; NAD/metabolism
Chemical Substances	Ligands ; NAD (0U46U6E8UK)
Language	English
Publishing date	2021-09-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	1410020-4
ISSN	1099-0461 ; 1095-6670
ISSN (online)	1099-0461
ISSN	1095-6670
DOI	10.1002/jbt.22925
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Article ; Online: Stopping the COVID-19 Pandemic

Md. Hasanul Banna Siam / Nahida Hannan Nishat / Ahsan Ahmed / Mohammad Sorowar Hossain

Journal of Pathogens, Vol

A Review on the Advances of Diagnosis, Treatment, and Control Measures

2020 Volume 2020

Abstract	With the continued spread of COVID-19 across the world, rapid diagnostic tools, readily available respurposable drugs, and prompt containment measures to control the SARS-CoV-2 infection are of paramount importance. Examples of recent advances in diagnostic tests are CRISPR technology, IgG assay, spike protein detection, and use of artificial intelligence. The gold standard reverse transcription polymerase chain (RT-PCR) has also been upgraded with point-of-care rapid tests. Supportive treatment, mechanical ventilation, and extracorporeal membrane oxygenation (ECMO) remain the primary choice, while therapeutic options include antivirals, antiparasitics, anti-inflammatories, interferon, convalescent plasma, monoclonal antibody, hyperimmunoglobulin, RNAi, and mesenchymal stem cell therapy. Different types of vaccines such as RNA, DNA, and lentiviral, inactivated, and viral vector are in clinical trials. Moreover, rapidly deployable and easy-to-transport innovative vaccine delivery systems are also in development. As countries have started easing down on the lockdown measures, the chance for a second wave of infection demands strict and rational control policies to keep fatalities minimized. An improved understanding of the advances in diagnostic tools, treatments, vaccines, and control measures for COVID-19 can provide references for further research and aid better containment strategies.
Keywords	Infectious and parasitic diseases ; RC109-216 ; Microbiology ; QR1-502 ; covid19
Subject code	610
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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