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  1. Article ; Online: Response to: The difference in the association between included ECPR patients and neurological outcomes.

    Watanabe, Makoto / Matsuyama, Tasuku / Kitamura, Tetsuhisa

    Critical care (London, England)

    2023  Volume 27, Issue 1, Page(s) 58

    MeSH term(s) Humans ; Out-of-Hospital Cardiac Arrest ; Cohort Studies ; Extracorporeal Membrane Oxygenation ; Temperature ; Cardiopulmonary Resuscitation
    Language English
    Publishing date 2023-02-10
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-023-04342-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Strategies for preventing sudden unexpected COVID-19 deaths at home

    Matsuyama, Tasuku

    Resuscitation

    2020  Volume 157, Page(s) 106–107

    Keywords Emergency ; Emergency Medicine ; Cardiology and Cardiovascular Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2020.09.039
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Impact of time to revascularization on outcomes in patients after out-of-hospital cardiac arrest with STEMI.

    Nakajima, Satoshi / Matsuyama, Tasuku / Kandori, Kenji / Okada, Asami / Okada, Yohei / Kitamura, Tetsuhisa / Ohta, Bon

    The American journal of emergency medicine

    2024  Volume 79, Page(s) 136–143

    Abstract: Background: International guidelines recommend emergency coronary angiography in patients after out-of-hospital cardiac arrest (OHCA) with ST-segment elevation on 12‑lead electrocardiography. However, the association between time to revascularization ... ...

    Abstract Background: International guidelines recommend emergency coronary angiography in patients after out-of-hospital cardiac arrest (OHCA) with ST-segment elevation on 12‑lead electrocardiography. However, the association between time to revascularization and outcomes remains unknown. This study aimed to evaluate the association between time to revascularization and outcomes in patients with OHCA due to ST-segment-elevation myocardial infarction (STEMI) who underwent percutaneous coronary intervention (PCI).
    Methods: This multicenter, retrospective, nationwide observational study included patients aged ≥18 years with OHCA due to STEMI who underwent PCI between 2014 and 2020. The time of the first return of spontaneous circulation (ROSC) was defined as the time of first ROSC during resuscitation, regardless of the pre-hospital or in-hospital setting. The primary outcome was a 1-month favorable neurological outcome, defined as cerebral performance category 1 or 2. Multivariable logistic regression analysis was used to assess the association between the time to revascularization and favorable neurological outcomes.
    Results: A total of 547 patients were included in this analysis. The multivariable logistic regression analysis showed that a shorter time from the first ROSC to revascularization was associated with 1-month favorable neurological outcomes (63/86 [73.3%] in the time from the first ROSC to revascularization ≤60 min group versus 98/193 [50.8%] in the >120 min group; adjusted OR, 0.26; 95% CI, 0.11-0.56; P for trend, 0.015).
    Conclusions: Shorter time to revascularization was significantly associated with 1-month favorable neurological outcomes in patients with OHCA due to STEMI who underwent PCI.
    MeSH term(s) Humans ; Adolescent ; Adult ; ST Elevation Myocardial Infarction/surgery ; Out-of-Hospital Cardiac Arrest/therapy ; Percutaneous Coronary Intervention ; Retrospective Studies ; Resuscitation ; Coronary Angiography ; Treatment Outcome ; Cardiopulmonary Resuscitation
    Language English
    Publishing date 2024-02-23
    Publishing country United States
    Document type Observational Study ; Multicenter Study ; Journal Article
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2024.02.030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Anti-Muscle-Specific Kinase (MuSK) Antibody-Positive Myasthenia Gravis Presenting With Dyspnea in an Elderly Woman: A Case Report.

    Shiozumi, Tadaharu / Okada, Nobunaga / Matsuyama, Tasuku / Yamahata, Yoshihiro / Ohta, Bon

    Cureus

    2023  Volume 15, Issue 12, Page(s) e50480

    Abstract: Myasthenia gravis (MG) is an autoimmune disease and represents one of the most common disorders associated with neuromuscular transmission defects. Within MG, the anti-muscle-specific kinase antibody-positive subtype (MuSK-positive MG) is rare. While it ... ...

    Abstract Myasthenia gravis (MG) is an autoimmune disease and represents one of the most common disorders associated with neuromuscular transmission defects. Within MG, the anti-muscle-specific kinase antibody-positive subtype (MuSK-positive MG) is rare. While it shares similarities with the common form of MG by presenting with ocular weakness, MuSK-positive MG typically presents with more atypical symptoms. Although MuSK-positive MG can lead to type 2 respiratory failure due to respiratory weakness, there have been limited reports where initial presentation involves only respiratory compromise. This study details a case of MuSK-positive MG presenting dyspnea. An 84-year-old female presented to the emergency department due to a three-day history of progressive respiratory distress, characterized by increased respiratory effort and shallow breathing, resulting in a diagnosis of type 2 respiratory failure. Despite the absence of neurological abnormalities, she tested positive for anti-muscle-specific kinase antibodies, confirming a diagnosis of MuSK-positive MG. This case highlights the significance of considering MG in the context of type 2 respiratory failure, even in the absence of typical neurological symptoms, especially in elderly patients.
    Language English
    Publishing date 2023-12-13
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.50480
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Sequence of Epinephrine and Advanced Airway Placement After Out-of-Hospital Cardiac Arrest.

    Okubo, Masashi / Komukai, Sho / Izawa, Junichi / Kiyohara, Kosuke / Matsuyama, Tasuku / Iwami, Taku / Kitamura, Tetsuhisa

    JAMA network open

    2024  Volume 7, Issue 2, Page(s) e2356863

    Abstract: Importance: While epinephrine and advanced airway management (AAM) (supraglottic airway insertion and endotracheal intubation) are commonly used for out-of-hospital cardiac arrest (OHCA), the optimal sequence of these interventions remains unclear.: ... ...

    Abstract Importance: While epinephrine and advanced airway management (AAM) (supraglottic airway insertion and endotracheal intubation) are commonly used for out-of-hospital cardiac arrest (OHCA), the optimal sequence of these interventions remains unclear.
    Objective: To evaluate the association of the sequence of epinephrine administration and AAM with patient outcomes after OHCA.
    Design, setting, and participants: This cohort study analyzed the nationwide, population-based OHCA registry in Japan and included adults (aged ≥18 years) with OHCA for whom emergency medical services personnel administered epinephrine and/or placed an advanced airway between January 1, 2014, and December 31, 2019. The data analysis was performed between October 1, 2022, and May 12, 2023.
    Exposure: The sequence of intravenous epinephrine administration and AAM.
    Main outcomes and measures: The primary outcome was 1-month survival. Secondary outcomes were 1-month survival with favorable functional status and prehospital return of spontaneous circulation. To control imbalances in measured patient demographics, cardiac arrest characteristics, and bystander and prehospital interventions, propensity scores and inverse probability of treatment weighting (IPTW) were performed for shockable and nonshockable initial rhythm subcohorts.
    Results: Of 259 237 eligible patients (median [IQR] age, 79 [69-86] years), 152 289 (58.7%) were male. A total of 21 592 patients (8.3%) had an initial shockable rhythm, and 237 645 (91.7%) had an initial nonshockable rhythm. Using IPTW, all covariates between the epinephrine-first and AAM-first groups were well balanced, with all standardized mean differences less than 0.100. After IPTW, the epinephrine-first group had a higher likelihood of 1-month survival for both shockable (odds ratio [OR], 1.19; 95% CI, 1.09-1.30) and nonshockable (OR, 1.28; 95% CI, 1.19-1.37) rhythms compared with the AAM-first group. For the secondary outcomes, the epinephrine-first group experienced an increased likelihood of favorable functional status and prehospital return of spontaneous circulation for both shockable and nonshockable rhythms compared with the AAM-first group.
    Conclusions and relevance: These findings suggest that for patients with OHCA, administration of epinephrine before placement of an advanced airway may be the optimal treatment sequence for improved patient outcomes.
    MeSH term(s) Adult ; Humans ; Male ; Adolescent ; Aged ; Female ; Out-of-Hospital Cardiac Arrest/therapy ; Cohort Studies ; Epinephrine/therapeutic use ; Intubation, Intratracheal ; Odds Ratio
    Chemical Substances Epinephrine (YKH834O4BH)
    Language English
    Publishing date 2024-02-05
    Publishing country United States
    Document type Journal Article
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2023.56863
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Cardiopulmonary resuscitation duration and favorable neurological outcome after out-of-hospital cardiac arrest: a nationwide multicenter observational study in Japan (the JAAM-OHCA registry).

    Matsuyama, Tasuku / Ohta, Bon / Kiyohara, Kosuke / Kitamura, Tetsuhisa

    Critical care (London, England)

    2022  Volume 26, Issue 1, Page(s) 120

    Abstract: Objective: We aimed to assess the association between cardiopulmonary resuscitation (CPR duration) and outcomes after OHCA.: Methods: This secondary analysis of a prospective, multicenter, observational study included adult non-traumatic OHCA ... ...

    Abstract Objective: We aimed to assess the association between cardiopulmonary resuscitation (CPR duration) and outcomes after OHCA.
    Methods: This secondary analysis of a prospective, multicenter, observational study included adult non-traumatic OHCA patients aged ≥ 18 years between June 2014 and December 2017. CPR duration was defined as the time from professional CPR initiation to the time of return of spontaneous circulation or termination of resuscitation. The primary outcome was 1-month survival, with favorable neurological outcomes defined by cerebral performance category 1 or 2. We performed multivariable logistic regression analysis to investigate the association between CPR duration and favorable neurological outcomes. We also investigated the association between CPR duration and favorable neurological outcomes stratified by case features, including the first documented cardiac rhythm, witnessed status, and presence of bystander CPR.
    Results: A total of 23,803 patients were included in this analysis. Multivariable logistic regression analysis demonstrated that the probability of favorable neurological outcomes decreased with CPR duration (i.e., 20.8% [226/1084] in the ≤ 20 min group versus 0.0% [0/708] in the 91-120 min group, P for trend < 0.001). Furthermore, the impact of CPR duration differed depending on the presence of case features; those with shockable, witnessed arrest, and bystander CPR were more likely to achieve favorable neurological outcomes after prolonged CPR duration > 30 min.
    Conclusion: The probability of favorable neurological outcome rapidly decreased within a few minutes of CPR duration. But, the impact of CPR duration may be influenced by each patient's clinical feature.
    MeSH term(s) Adult ; Cardiopulmonary Resuscitation ; Emergency Medical Services ; Humans ; Japan ; Out-of-Hospital Cardiac Arrest ; Prospective Studies ; Registries ; Time Factors
    Language English
    Publishing date 2022-05-02
    Publishing country England
    Document type Journal Article ; Multicenter Study ; Observational Study
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-022-03994-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Intra-arrest partial carbon dioxide level and favorable neurological outcome after out-of-hospital cardiac arrest: a nationwide multicenter observational study in Japan (the JAAM-OHCA registry).

    Matsuyama, Tasuku / Ohta, Bon / Kiyohara, Kosuke / Kitamura, Tetsuhisa

    European heart journal. Acute cardiovascular care

    2022  Volume 12, Issue 1, Page(s) 14–21

    Abstract: Aims: Little is known about whether guideline-recommended ventilation during cardiopulmonary resuscitation results in optimal partial carbon dioxide (pCO2) levels or favorable outcomes. This study aimed to evaluate the association between intra-arrest ... ...

    Abstract Aims: Little is known about whether guideline-recommended ventilation during cardiopulmonary resuscitation results in optimal partial carbon dioxide (pCO2) levels or favorable outcomes. This study aimed to evaluate the association between intra-arrest pCO2 level and the outcome after out-of-hospital cardiac arrest (OHCA).
    Methods and results: We performed a secondary analysis of a multicenter observational study, including adult patients with OHCA who did not achieve a return of spontaneous circulation (ROSC) upon hospital arrival and whose blood gas analysis was performed before the ROSC between June 2014 and December 2017. The patients were categorized into four quartiles based on their intra-arrest carbon dioxide levels: Quartile 1 (<66.0 mmHg), Quartile 2 (66.1-87.2 mmHg), Quartile 3 (87.3-113.5 mmHg), and Quartile 4 (≥113.6 mmHg). The primary outcome was 1-month survival with favorable neurological outcomes defined as cerebral performance Category 1 or 2. Multivariate logistic regression analysis was used to evaluate the association between pCO2 and favorable neurological outcomes. During the study period, 20 913 patients were eligible for the analysis. The proportion of favorable neurological outcomes was 1.8% (90/5133), 0.7% (35/5232), 0.4% (19/5263), and 0.2% (9/5285) in Quartiles 1-4, respectively. Multivariable logistic regression analysis demonstrated that the probability of favorable neurological outcome decreased with increased intra-arrest carbon dioxide levels (i.e. Q1 vs. Q4, adjusted odds ratio 0.25, 95% confidence interval 0.16-0.55, P for trend <0.001).
    Conclusion: Lower intra-arrest pCO2 levels were associated with a favorable neurological outcome.
    MeSH term(s) Adult ; Humans ; Carbon Dioxide ; Out-of-Hospital Cardiac Arrest ; Japan/epidemiology ; Cardiopulmonary Resuscitation/methods ; Registries ; Emergency Medical Services
    Chemical Substances Carbon Dioxide (142M471B3J)
    Language English
    Publishing date 2022-11-29
    Publishing country England
    Document type Multicenter Study ; Observational Study ; Journal Article
    ZDB-ID 2663340-1
    ISSN 2048-8734 ; 2048-8726
    ISSN (online) 2048-8734
    ISSN 2048-8726
    DOI 10.1093/ehjacc/zuac152
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Correction: External validation of 5A score model for predicting in-hospital mortality among the accidental hypothermia patients: JAAM-Hypothermia study 2018-2019 secondary analysis.

    Okada, Yohei / Matsuyama, Tasuku / Hayashida, Kei / Takauji, Shuhei / Kanda, Jun / Yokobori, Shoji

    Journal of intensive care

    2022  Volume 10, Issue 1, Page(s) 27

    Language English
    Publishing date 2022-06-09
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2739853-5
    ISSN 2052-0492
    ISSN 2052-0492
    DOI 10.1186/s40560-022-00617-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Association between eGFR and neurological outcomes among patients with out-of-hospital cardiac arrest: A nationwide prospective study in Japan.

    Kandori, Kenji / Okada, Asami / Nakajima, Satoshi / Matsuyama, Tasuku / Kitamura, Tetsuhisa / Narumiya, Hiromichi / Iizuka, Ryoji / Hitosugi, Masahito / Okada, Yohei

    Acute medicine & surgery

    2024  Volume 11, Issue 1, Page(s) e952

    Abstract: Aim: We aimed to investigate the association between estimated glomerular filtration rate and prognosis in out-of-hospital cardiac arrest patients and explore the heterogeneity of the association.: Methods: Patients experiencing out-of-hospital ... ...

    Abstract Aim: We aimed to investigate the association between estimated glomerular filtration rate and prognosis in out-of-hospital cardiac arrest patients and explore the heterogeneity of the association.
    Methods: Patients experiencing out-of-hospital cardiac arrest due to medical causes and registered in the JAAM-OHCA Registry between June 2014 and December 2019 were stratified into shockable rhythm, pulseless electrical activity, and asystole groups according to the cardiac rhythm at the scene. The primary outcome was a 1-month favorable neurological status. Adjusted odds ratios with 95% confidence intervals were calculated to investigate the association between estimated glomerular filtration rate and outcomes using a logistic model.
    Results: Of the 19,443 patients included, 2769 had initial shockable rhythm at the scene, 5339 had pulseless electrical activity, and 11,335 had asystole. As the estimated glomerular filtration rate decreased, the adjusted odds ratio for a 1-month favorable neurological status decreased among those with initial shockable rhythm (estimated glomerular filtration rate, adjusted odds ratio [95% CI]: 45-59 mL/min/1.73 m
    Conclusion: The estimated glomerular filtration rate is associated with neurological prognosis in out-of-hospital cardiac arrest patients with initial shockable rhythm at the scene but not in those with initial non-shockable rhythm.
    Language English
    Publishing date 2024-04-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2751184-4
    ISSN 2052-8817 ; 2052-8817
    ISSN (online) 2052-8817
    ISSN 2052-8817
    DOI 10.1002/ams2.952
    Database MEDical Literature Analysis and Retrieval System OnLINE

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