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Article ; Online: sQuiz your knowledge! A firm reddish lesion arising in an old scar.

Li, Yurong / Wang, Yang / Sun, Jingru

2023 Volume 33, Issue 3, Page(s) 334–335

Language	English
Publishing date	2023-08-18
Publishing country	France
Document type	Journal Article
ZDB-ID	1128666-0
ISSN	1952-4013 ; 1167-1122
ISSN (online)	1952-4013
ISSN	1167-1122
DOI	10.1684/ejd.2023.4509
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Zs.A 3484: Show issues

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Article ; Online: Novel

Piao, Yurong / Li, Rongmin / Wang, Yingjie / Chen, Congli / Sang, Yanmei

Journal of clinical research in pediatric endocrinology

2024

Abstract: 3M syndrome is an autosomal recessive disorder characterized by short stature and skeletal developmental abnormalities. In this study, a Chinese patient with 3M syndrome was presented. A ... ...

Abstract	3M syndrome is an autosomal recessive disorder characterized by short stature and skeletal developmental abnormalities. In this study, a Chinese patient with 3M syndrome was presented. A novel
Language	English
Publishing date	2024-02-26
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	2641608-6
ISSN	1308-5735 ; 1308-5727
ISSN (online)	1308-5735
ISSN	1308-5727
DOI	10.4274/jcrpe.galenos.2024.2023-11-6
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Zs.A 6942: Show issues

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Article: Function and prognostic value of basement membrane -related genes in lung adenocarcinoma.

Zhang, Yurong / Li, Tingting / Liu, Huanqing / Wang, Li

Frontiers in pharmacology

2023 Volume 14, Page(s) 1185380

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2023-05-05
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587355-6
ISSN	1663-9812
ISSN	1663-9812
DOI	10.3389/fphar.2023.1185380
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Article: Accuracy of radiomics in the diagnosis and preoperative high-risk assessment of endometrial cancer: a systematic review and meta-analysis.

He, Junmei / Liu, Yurong / Li, Jinzhu / Liu, Shuang

Frontiers in oncology

2024 Volume 14, Page(s) 1334546

Abstract: Background: With the increasing use of radiomics in cancer diagnosis and treatment, it has been applied by some researchers to the preoperative risk assessment of endometrial cancer (EC) patients. However, comprehensive and systematic evidence is needed ...

Abstract	Background: With the increasing use of radiomics in cancer diagnosis and treatment, it has been applied by some researchers to the preoperative risk assessment of endometrial cancer (EC) patients. However, comprehensive and systematic evidence is needed to assess its clinical value. Therefore, this study aims to investigate the application value of radiomics in the diagnosis and treatment of EC. Methods: Pubmed, Cochrane, Embase, and Web of Science databases were retrieved up to March 2023. Preoperative risk assessment of EC included high-grade EC, lymph node metastasis, deep myometrial invasion status, and lymphovascular space invasion status. The quality of the included studies was appraised utilizing the RQS scale. Results: A total of 33 primary studies were included in our systematic review, with an average RQS score of 7 (range: 5-12). ML models based on radiomics for the diagnosis of malignant lesions predominantly employed logistic regression. In the validation set, the pooled c-index of the ML models based on radiomics and clinical features for the preoperative diagnosis of endometrial malignancy, high-grade tumors, lymph node metastasis, lymphovascular space invasion, and deep myometrial invasion was 0.900 (95%CI: 0.871-0.929), 0.901 (95%CI: 0.877-0.926), 0.906 (95%CI: 0.882-0.929), 0.795 (95%CI: 0.693-0.897), and 0.819 (95%CI: 0.705-0.933), respectively. Conclusions: Radiomics shows excellent accuracy in detecting endometrial malignancies and in identifying preoperative risk. However, the methodological diversity of radiomics results in significant heterogeneity among studies. Therefore, future research should establish guidelines for radiomics studies based on different imaging sources. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=364320 identifier CRD42022364320.
Language	English
Publishing date	2024-01-25
Publishing country	Switzerland
Document type	Systematic Review
ZDB-ID	2649216-7
ISSN	2234-943X
ISSN	2234-943X
DOI	10.3389/fonc.2024.1334546
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Article ; Online: PASTFNet: a paralleled attention spatio-temporal fusion network for micro-expression recognition.

Tian, Haichen / Gong, Weijun / Li, Wei / Qian, Yurong

Medical & biological engineering & computing

2024

Abstract: Micro-expressions (MEs) play such an important role in predicting a person's genuine emotions, as to make micro-expression recognition such an important resea rch focus in recent years. Most recent researchers have made efforts to recognize MEs with ... ...

Abstract	Micro-expressions (MEs) play such an important role in predicting a person's genuine emotions, as to make micro-expression recognition such an important resea rch focus in recent years. Most recent researchers have made efforts to recognize MEs with spatial and temporal information of video clips. However, because of their short duration and subtle intensity, capturing spatio-temporal features of micro-expressions remains challenging. To effectively promote the recognition performance, this paper presents a novel paralleled dual-branch attention-based spatio-temporal fusion network (PASTFNet). We jointly extract short- and long-range spatial relationships in spatial branch. Inspired by the composite architecture of the convolutional neural network (CNN) and long short-term memory (LSTM) for temporal modeling, we propose a novel attention-based multi-scale feature fusion network (AMFNet) to encode features of sequential frames, which can learn more expressive facial-detailed features for it implements the integrated use of attention and multi-scale feature fusion, then design an aggregation block to aggregate and acquire temporal features. At last, the features learned by the above two branches are fused to accomplish expression recognition with outstanding effect. Experiments on two MER datasets (CASMEII and SAMM) show that the PASTFNet model achieves promising ME recognition performance compared with other methods.
Language	English
Publishing date	2024-02-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	282327-5
ISSN	1741-0444 ; 0025-696X ; 0140-0118
ISSN (online)	1741-0444
ISSN	0025-696X ; 0140-0118
DOI	10.1007/s11517-024-03041-y
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Zs.A 294: Show issues

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Article ; Online: Novel insights into adaptive evolution based on the unusual AT-skew in Acheilognathus gracilis mitogenome and phylogenetic relationships of bitterling.

Li, Yuxuan / Yi, Hongbo / Zhu, Yurong

Gene

2024 Volume 902, Page(s) 148154

Abstract: Acheilognathus gracilis, a bitterling species, distribute in lower reaches of Yangtze River. They are identified as the top-priority bitterling species for conservation as having high evolutionary distinctiveness and are at risk of extinction. In present ...

Abstract	Acheilognathus gracilis, a bitterling species, distribute in lower reaches of Yangtze River. They are identified as the top-priority bitterling species for conservation as having high evolutionary distinctiveness and are at risk of extinction. In present study, we first sequenced the complete mitogenome of A. gracilis and analyzed its phylogenetic position using 13 PCGs. The A. gracilis mitogenome is 16,774 bp in length, including 13 protein-coding genes, 2 ribosomal RNAs, 22 transfer RNAs, a control region and the origin of the light strand replication. The overall base composition of A. gracilis in descending order is T 27.9 %, A 27.7 %, C 26.1 % and G 18.3 %, shows a unusual AT-skew with slightly negative. Further investigation revealed A. gracilis uses excess T over A in NADH dehydrogenase 5 (nd5), whereas the most of other bitterlings are biased toward to use A not T, implying there is likely to be unique strategy of adaptive evolution in A. gracilis. We also compared 13 PCGs of 30 bitterling mitogenomes and the results exhibit highly conservative. Phylogenetic trees constructed by 13 PCGs strongly support the monophyly of Acheilognathus and the paraphyly of Rhodeus and Tanakia. Current results will provide valuable information for follow-up research on conservation of species facing with serious population decline and can provide novel insights into the phylogenetic analysis and evolutionary biology research.
MeSH term(s)	Animals ; Phylogeny ; Genome, Mitochondrial ; Cyprinidae/genetics ; Cypriniformes/genetics ; Base Sequence
Language	English
Publishing date	2024-01-11
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	391792-7
ISSN	1879-0038 ; 0378-1119
ISSN (online)	1879-0038
ISSN	0378-1119
DOI	10.1016/j.gene.2024.148154
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Zs.A 1357: Show issues

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Article: Effects of glycated serum protein, homocysteine, and cystatin-C levels on pregnancy outcomes in patients with gestational diabetes mellitus.

Chen, Yuhua / Li, Chunfang / Lei, Yurong / Zhang, Fen

Pakistan journal of medical sciences

2024 Volume 40, Issue 4, Page(s) 572–576

Abstract: Objective: To explore the effects of serum glycated serum protein (GSP), homocysteine (Hcy) and cystatin-C (Cys-C) levels on pregnancy outcomes in patients with gestational diabetes mellitus (GDM).: Methods: Retrospective selection of 247 pregnant ... ...

Abstract	Objective: To explore the effects of serum glycated serum protein (GSP), homocysteine (Hcy) and cystatin-C (Cys-C) levels on pregnancy outcomes in patients with gestational diabetes mellitus (GDM). Methods: Retrospective selection of 247 pregnant women who underwent normal prenatal examinations in The Yan'an People's Hospital from January 2020 to May 2022 were included in this retrospective study. Among them, 119 were pregnant women with diabetes (GDM-group) and 128 were pregnant women with normal blood glucose (Normal-group). The levels of serum GSP, HCY, CYS-C, and incidence of adverse pregnancy outcomes were compared between the two groups. The clinical value of levels of serum GSP, Hcy, and Cys-C in predicting adverse pregnancy outcomes were analyzed. Results: Compared with the Normal-group, the overall incidence of adverse pregnancy outcomes, serum GSP, Hcy, and Cys-C levels in the GDM-group were significantly higher ( Conclusions: GDM is associated with a high risk of adverse pregnancy outcomes. Levels of serum GSP, Hcy, and Cys-C are higher in patients with GDM. The higher the levels of GSP, Hcy, and Cys-C, the greater the risk of adverse pregnancy outcomes. Combining these three indicators can effectively predict maternal pregnancy outcomes.
Language	English
Publishing date	2024-03-13
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	2032827-8
ISSN	1681-715X ; 1682-024X ; 1017-4699
ISSN (online)	1681-715X
ISSN	1682-024X ; 1017-4699
DOI	10.12669/pjms.40.4.8988
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Zs.A 3948: Show issues

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Article ; Online: Quercetin Regulates Lipid Metabolism and Fat Accumulation by Regulating Inflammatory Responses and Glycometabolism Pathways: A Review.

Wang, Yaodong / Li, Zezheng / He, Jianhua / Zhao, Yurong

Nutrients

2024 Volume 16, Issue 8

Abstract: Fat synthesis and lipolysis are natural processes in growth and have a close association with health. Fat provides energy, maintains physiological function, and so on, and thus plays a significant role in the body. However, excessive/abnormal fat ... ...

Abstract	Fat synthesis and lipolysis are natural processes in growth and have a close association with health. Fat provides energy, maintains physiological function, and so on, and thus plays a significant role in the body. However, excessive/abnormal fat accumulation leads to obesity and lipid metabolism disorder, which can have a detrimental impact on growth and even harm one's health. Aside from genetic effects, there are a range of factors related to obesity, such as excessive nutrient intake, inflammation, glycometabolism disease, and so on. These factors could serve as potential targets for anti-obesity therapy. Quercetin is a flavonol that has received a lot of attention recently because of its role in anti-obesity. It was thought to have the ability to regulate lipid metabolism and have a positive effect on anti-obesity, but the processes are still unknown. Recent studies have shown the role of quercetin in lipid metabolism might be related to its effects on inflammatory responses and glycometabolism. The references were chosen for this review with no date restrictions applied based on the topics they addressed, and the databases PubMed and Web of Sicence was used to conduct the references research, using the following search terms: "quercetin", "obesity", "inflammation", "glycometabolism", "insulin sensitivity", etc. This review summarizes the potential mechanisms of quercetin in alleviating lipid metabolism through anti-inflammatory and hypoglycemic signaling pathways, and describes the possible signaling pathways in the interaction of inflammation and glycometabolism, with the goal of providing references for future research and application of quercetin in the regulation of lipid metabolism.
MeSH term(s)	Quercetin/pharmacology ; Humans ; Lipid Metabolism/drug effects ; Inflammation/metabolism ; Signal Transduction/drug effects ; Obesity/metabolism ; Obesity/drug therapy ; Animals ; Insulin Resistance ; Anti-Inflammatory Agents/pharmacology ; Adipose Tissue/metabolism ; Adipose Tissue/drug effects
Chemical Substances	Quercetin (9IKM0I5T1E) ; Anti-Inflammatory Agents
Language	English
Publishing date	2024-04-09
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu16081102
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Article ; Online: Effect of individualized narrative nursing mode on recovery of elderly patients with fracture complicated with cerebrovascular accident.

Wang, Yurong / Zhang, Fang / Li, Cuihua

Medicine

2024 Volume 103, Issue 3, Page(s) e36901

Abstract: Fractures often occur in elderly patients. Osteoporosis caused by massive loss of calcium ions in the bones of elderly patients can easily lead to femoral fractures after suffering a low- and medium-energy injury. With the gradual entry of the aging ... ...

Abstract	Fractures often occur in elderly patients. Osteoporosis caused by massive loss of calcium ions in the bones of elderly patients can easily lead to femoral fractures after suffering a low- and medium-energy injury. With the gradual entry of the aging society in China, the incidence of senile fracture is also gradually increasing. However, there is no report on the application of personalized narrative nursing to the mental health, cognitive function, and limb function recovery of elderly patients with fracture complicated with cerebrovascular accident, in order to enhance the cognitive level of elderly patients with fracture complicated with cerebrovascular accident. This study was specially conducted with a positive attitude toward the disease and improving the life quality. During July 2018 to July 2021, 80 elderly patients with fracture complicated with cerebrovascular accident cured were selected in our hospital. The patients were arbitrarily classified into an assigned control group (n = 40) and a study group (n = 40). The former received routine nursing, and the latter received personalized narrative nursing mode. The nursing satisfaction, functional independence scale (FIM), self-rating anxiety scale (SAS), self-rating depression scale (SDS), cognitive function, fracture healing time, length of hospital stays, and hospitalization expenses were compared. The study group had a satisfaction rate of 100.00%, while the control group had 87.50%. The nursing satisfaction of the study group was higher (P < .05). After 3 months of nursing, the FIM scores augmented. The FIM scores of upper and lower limbs in the study group were remarkably higher (P < .05). A decrease in SAS and SDS scores was observed. The SAS and SDS scores of the study group were lower (P < .05). Three months after discharge, the cognitive function score augmented. At 3 months after discharge, the study group had a higher cognitive function score (P < .05). The fracture healing time, length of stay, and cost of hospitalization in the study group were lower (P < .05). Personalized narrative nursing model can successfully enhance the mental health and cognitive function of elderly patients with fracture complicated with cerebrovascular accident, enhance the recovery of limb function, promote patients' nursing satisfaction, and alleviate the economic burden.
MeSH term(s)	Humans ; Aged ; Treatment Outcome ; Stroke/complications ; Fractures, Bone ; Hospitalization ; Length of Stay
Language	English
Publishing date	2024-01-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000036901
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Ua VI Zs.171: Show issues

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Article ; Online: Mn

Su, Renyuan / Zhu, Weikai / Liang, Kang / Wei, Peng / Li, Jianbin / Liu, Wenjun / Ren, Yurong

Molecules (Basel, Switzerland)

2023 Volume 28, Issue 3

Abstract: ... ...

Abstract	Na
Language	English
Publishing date	2023-02-01
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules28031409
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