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  1. Article ; Online: Corrigendum to Adolescent Vaping-Associated Trauma in the Western United States [J Surg Res. 2022 Aug;276:251-255].

    Russell, Katie W / Katz, Micah G / Phillips, Ryan C / Kelley-Quon, Lorraine I / Acker, Shannon N / Shahi, Niti / Lee, Justin H / Fialkowski, Elizabeth A / Nacharaju, Deepthi / Smith, Caitlin A / Jensen, Aaron R / Mueller, Claudia M / Padilla, Benjamin E / Ignacio, Romeo C / Ourshalimian, Shadassa / Wang, Kasper S / Ostlie, Daniel J / Fenton, Stephen J / Kastenberg, Zachary J

    The Journal of surgical research

    2023  Volume 294, Page(s) 247–248

    Language English
    Publishing date 2023-11-03
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 80170-7
    ISSN 1095-8673 ; 0022-4804
    ISSN (online) 1095-8673
    ISSN 0022-4804
    DOI 10.1016/j.jss.2023.09.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 178: Show issues Location:
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  2. Article ; Online: Mapping of uranium particles on J-type swipes with microextraction-ICP-MS.

    Bradley, Veronica C / Burleson, Jacob / Andrews, Hunter B / Thompson, Cyril V / Spano, Tyler L / Dunlap, Daniel R / Zirakparvar, N Alex / Ticknor, Brian W / Hexel, Cole R / Manard, Benjamin T

    The Analyst

    2024  Volume 149, Issue 8, Page(s) 2244–2251

    Abstract: A microextraction liquid sampling system coupled to a quadrupole inductively coupled plasma-mass spectrometer (ICP-MS) was utilized to spatially discern uranium particles, isotopically, on a cellulose-based swipe material ( ...

    Abstract A microextraction liquid sampling system coupled to a quadrupole inductively coupled plasma-mass spectrometer (ICP-MS) was utilized to spatially discern uranium particles, isotopically, on a cellulose-based swipe material (
    Language English
    Publishing date 2024-04-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 210747-8
    ISSN 1364-5528 ; 0003-2654
    ISSN (online) 1364-5528
    ISSN 0003-2654
    DOI 10.1039/d3an02101g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Tribute to Peter J. Rossky.

    Pettitt, B Montgomery / Schwartz, Benjamin J / Sterpone, Fabio / Túri, László / Willard, Adam P

    The journal of physical chemistry. B

    2020  Volume 124, Issue 47, Page(s) 10591–10593

    Language English
    Publishing date 2020-11-21
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5207
    ISSN (online) 1520-5207
    DOI 10.1021/acs.jpcb.0c09810
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  4. Book: Die Evidenz des 10-Stufen-Modells nach J. E. Upledger bei verschiedenen Krankheitsbildern

    Stein, Heinz von der / Alt, Denys Benjamin

    2015  

    Author's details Heinz von der Stein ; Denys Benjamin Alt
    Keywords Parietal Lift ; 10-Stufen-Modell nach J.E. Upledger ; primäre Atembewegung PRM ; TMJ-Kompression-Dekompression ; Arachnoidea ; Frontal Lift ; CV 4-Technik ; Leitfaden ; SSB Dysfunktion ; Kraniosakral-Therapie
    Subject Kraniosakraltherapie ; Cranio-Sacral-Therapie ; Cranio-sakrale Therapie ; Kraniosakrale Osteopathie ; Cranio-sacrale Sofort-Visualisierung ; Cranio-Sacral-Methode ; Craniale Osteopathie ; Craniosacral Therapie ; Craniosacral-Therapie ; Cranio-sacrale Osteopathie
    Subject code 615.533
    Language German
    Size XVIII, 125 S. : zahlr. Ill., 21 cm, 174 g
    Publisher Mainz
    Publishing place Aachen
    Publishing country Germany
    Document type Book
    Note Literaturangaben
    HBZ-ID HT018815936
    ISBN 978-3-95886-036-0 ; 3-95886-036-2
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2015 A 4183 available for loan (reading room) Lesesaal EG

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  5. Article ; Online: Immunomodulatory Effects of Histone Variant H2A.J in Ionizing Radiation Dermatitis.

    Tewary, Gargi / Freyter, Benjamin / Al-Razaq, Mutaz Abd / Auerbach, Hendrik / Laschke, Matthias W / Kübelbeck, Tanja / Kolb, Antonia / Mangelinck, Adèle / Mann, Carl / Kramer, Daniela / Rübe, Claudia E

    International journal of radiation oncology, biology, physics

    2023  Volume 118, Issue 3, Page(s) 801–816

    Abstract: Purpose: Histone variant H2A.J is associated with premature senescence after ionizing radiation ... IR) and modulates senescence-associated secretory phenotype (SASP). Using constitutive H2A.J ... knock-out mice, the role of H2A.J was investigated in radiation dermatitis.: Methods and materials: H2A.J wild ...

    Abstract Purpose: Histone variant H2A.J is associated with premature senescence after ionizing radiation (IR) and modulates senescence-associated secretory phenotype (SASP). Using constitutive H2A.J knock-out mice, the role of H2A.J was investigated in radiation dermatitis.
    Methods and materials: H2A.J wild-type (WT) and knock-out (KO) mice were exposed to moderate or high IR doses (≤20 Gy, skinfold IR). Radiation-induced skin reactions were investigated up to 2 weeks post-IR at macroscopic and microscopic levels. H2A.J and other senescence markers, as well as DNA damage and proliferation markers, were studied by immunohistochemistry, immunofluorescence, and electron microscopy. After high-dose IR, protein-coding transcriptomes were analyzed by RNA sequencing, immune cell infiltration by flow cytometry, and gene expression by reverse transcription polymerase chain reaction in (non-) irradiated WT versus KO skin.
    Results: In WT skin, epidermal keratinocytes showed time- and dose-dependent H2A.J accumulation after IR exposure. Unexpectedly, stronger inflammatory reactions with increased epidermal thickness and progressive hair follicle loss were observed in irradiated KO versus WT skin. Clearly more radiation-induced senescence was observed in keratinocyte populations of KO skin after moderate and high doses, with hair follicle stem cells being particularly badly damaged, leading to follicle atrophy. After high-dose IR, transcriptomic analysis revealed enhanced senescence-associated signatures in irradiated KO skin, with intensified release of SASP factors. Flow cytometric analysis indicated increased immune cell infiltration in both WT and KO skin; however, specific chemokine-mediated signaling in irradiated KO skin led to more neutrophil recruitment, thereby aggravating radiation toxicities. Increased skin damage in irradiated KO skin led to hyperproliferation, abnormal differentiation, and cornification of keratinocytes, accompanied by increased upregulation of transcription-factor JunB.
    Conclusions: Lack of radiation-induced H2A.J expression in keratinocytes is associated with increased senescence induction, modulation of SASP expression, and exacerbated inflammatory skin reactions. Hence, epigenetic H2A.J-mediated gene expression in response to IR regulates keratinocyte immune functions and plays an essential role in balancing the inflammatory response during radiation dermatitis.
    MeSH term(s) Animals ; Mice ; Histones/metabolism ; Skin/radiation effects ; Keratinocytes/physiology ; Radiation, Ionizing ; Radiodermatitis ; Cellular Senescence/radiation effects
    Chemical Substances Histones
    Language English
    Publishing date 2023-09-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197614-x
    ISSN 1879-355X ; 0360-3016
    ISSN (online) 1879-355X
    ISSN 0360-3016
    DOI 10.1016/j.ijrobp.2023.09.022
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    Zs.A 1218: Show issues Location:
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  6. Article ; Online: Corrigendum to "Making Space for Reading as a Faculty Member" [Am J Pharm Educ 87 (2023) 100115].

    Charrois, Theresa L / Janke, Kristin K / Covvey, Jordan R / Aronson, Benjamin D

    American journal of pharmaceutical education

    2024  Volume 88, Issue 2, Page(s) 100652

    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 603807-4
    ISSN 1553-6467 ; 0002-9459
    ISSN (online) 1553-6467
    ISSN 0002-9459
    DOI 10.1016/j.ajpe.2024.100652
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    Zs.A 924: Show issues Location:
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  7. Article ; Online: Dose-dependent relationship between SGLT2 inhibitor hold time and risk for postoperative anion gap acidosis. Response to Br J Anaesth 2023; 131: 682-686. Br J Anaesth 2024; 132: 822-3.

    Steinhorn, Benjamin

    British journal of anaesthesia

    2024  Volume 132, Issue 5, Page(s) 993–994

    MeSH term(s) Humans ; Sodium-Glucose Transporter 2 Inhibitors/adverse effects ; Acid-Base Equilibrium ; Acidosis ; Diabetic Ketoacidosis ; Diabetes Mellitus, Type 2
    Chemical Substances Sodium-Glucose Transporter 2 Inhibitors
    Language English
    Publishing date 2024-03-05
    Publishing country England
    Document type Letter
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1016/j.bja.2024.01.041
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  8. Article ; Online: Role of Histone Variant H2A.J in Fine-Tuning Chromatin Organization for the Establishment of Ionizing Radiation-Induced Senescence.

    Abd Al-Razaq, Mutaz A / Freyter, Benjamin M / Isermann, Anna / Tewary, Gargi / Mangelinck, Adèle / Mann, Carl / Rübe, Claudia E

    Cells

    2023  Volume 12, Issue 6

    Abstract: ... with down- or up-regulated H2A.J expression were exposed to ionizing radiation and were analyzed ... image analysis of H2A.J-immunohistochemistry.: Results: Differential incorporation of H2A.J has profound ... Integrative analyses of ATAC-seq and RNA-seq datasets indicate that H2A.J-associated changes in chromatin ...

    Abstract Purpose: Radiation-induced senescence is characterized by profound changes in chromatin organization with the formation of
    Experimental design: Primary and genetically-modified lung fibroblasts with down- or up-regulated H2A.J expression were exposed to ionizing radiation and were analyzed for the formation of SAHF and DNA-SCARS by immunofluorescence microscopy. Dynamic changes in chromatin organization and accessibility, transcription factor recruitment, and transcriptome signatures were mapped by ATAC-seq and RNA-seq analysis. The secretion of SASP factors and potential bystander effects were analyzed by ELISA and RT-PCR. Lung tissue of mice exposed to different doses were analyzed by the digital image analysis of H2A.J-immunohistochemistry.
    Results: Differential incorporation of H2A.J has profound effects on higher-order chromatin organization and on establishing the epigenetic state of senescence. Integrative analyses of ATAC-seq and RNA-seq datasets indicate that H2A.J-associated changes in chromatin accessibility of regulatory regions decisively modulates transcription factor recruitment and inflammatory gene expression, resulting in an altered SASP secretome. In lung parenchyma, pneumocytes show dose-dependent H2A.J expression in response to radiation-induced DNA damage, therefore contributing to pro-inflammatory tissue reactions.
    Conclusions: The fine-tuned incorporation of H2A.J defines the epigenetic landscape for driving the senescence programme in response to radiation-induced DNA damage. Deregulated H2A.J deposition affects chromatin remodeling, transcription factor recruitment, and the pro-inflammatory secretome. Our findings provide new mechanistic insights into DNA-damage triggered epigenetic mechanisms governing the biological processes of radiation-induced injury.
    MeSH term(s) Animals ; Mice ; Histones/metabolism ; Cicatrix ; Chromatin ; Heterochromatin ; Transcription Factors/metabolism ; Radiation, Ionizing
    Chemical Substances Histones ; Chromatin ; Heterochromatin ; Transcription Factors
    Language English
    Publishing date 2023-03-16
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells12060916
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  9. Article ; Online: Corrigendum to 'Dose-dependent relationship between SGLT2 inhibitor hold time and risk for postoperative anion gap acidosis: a single-centre retrospective analysis' (Br J Anaesth 2023;131:682-6).

    Steinhorn, Benjamin / Wiener-Kronish, Jeanine

    British journal of anaesthesia

    2024  Volume 132, Issue 4, Page(s) 829

    Language English
    Publishing date 2024-02-09
    Publishing country England
    Document type Published Erratum
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1016/j.bja.2024.01.024
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  10. Article ; Online: Intraoperative hypotension is not associated with reduced atrial fibrillation or hospital length of stay. Comment on Br J Anaesth 2023; 131: 823-31.

    Payne, Thomas / Moran, Benjamin

    British journal of anaesthesia

    2023  Volume 132, Issue 1, Page(s) 181–183

    MeSH term(s) Humans ; Atrial Fibrillation ; Length of Stay ; Hypotension/etiology ; Postoperative Complications
    Language English
    Publishing date 2023-11-22
    Publishing country England
    Document type Letter
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1016/j.bja.2023.10.019
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