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Article ; Online: Letter to the editor: Time to consider unusual or severe headache and fatigue as indicator symptoms for COVID-19 testing?

Tostmann, Alma

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

2022 Volume 27, Issue 1

MeSH term(s)	COVID-19 ; COVID-19 Testing ; Fatigue/diagnosis ; Fatigue/etiology ; Headache/diagnosis ; Headache/etiology ; Humans ; SARS-CoV-2
Language	English
Publishing date	2022-01-06
Publishing country	Sweden
Document type	Letter ; Comment
ZDB-ID	1338803-4
ISSN	1560-7917 ; 1025-496X
ISSN (online)	1560-7917
ISSN	1025-496X
DOI	10.2807/1560-7917.ES.2022.27.1.2101188
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Book ; Thesis: Challenges in tuberculosis treatment and control

Tostmann, Alma

studies from the Netherlands and Tanzania

2009

Author's details	door Alma Tostmann
Language	English ; Dutch
Size	162 S. : Ill., graph. Darst.
Publishing country	Netherlands
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Nijmegen, Univ., Diss., 2009
Note	Zsfassung in niederländ. Sprache
HBZ-ID	HT016238186
ISBN	978-90-9024768-7 ; 90-9024768-8
Database	Catalogue ZB MED Medicine, Health

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Shelf mark	Loan status	Location
2010 E 1309	order for loan	Magazin

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Article ; Online: Field Epidemiology: Fit for the future.

Hahné, Susan / Hammer, Charlotte / Tostmann, Alma / Whelan, Jane / Williams, Christopher

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

2023 Volume 28, Issue 36

Abstract: In recent years, field epidemiologists have embraced rapidly evolving digital tools, data sources and technologies, and collaborated with an ever-growing field of scientific specialisms. The COVID-19 pandemic put field epidemiology under unprecedented ... ...

Abstract	In recent years, field epidemiologists have embraced rapidly evolving digital tools, data sources and technologies, and collaborated with an ever-growing field of scientific specialisms. The COVID-19 pandemic put field epidemiology under unprecedented demand and scrutiny. As the COVID-19 emergency recedes, it is timely to reflect on the core values of our profession and the unique challenges and opportunities that lie ahead. In November 2022, alumni of the European Programme for Intervention Epidemiology Training (EPIET) and the European Public Health Microbiology (EUPHEM) training programme celebrated 25 years of EPIET, and the present and future of field epidemiology was discussed. The output was recorded and qualitatively analysed. This Perspective reflects the authors' interpretation of the discussion. We should reaffirm our commitment to field epidemiology's core strengths: competence and rigour in epidemiology, surveillance, outbreak investigation and applied research, leading to timely and actionable evidence for public health. Our future success will be defined by an ability to adapt, collaborate, harness innovation, communicate and, ultimately, by our tangible impact on protecting and improving health.
MeSH term(s)	Humans ; COVID-19/epidemiology ; Pandemics/prevention & control ; Disease Outbreaks/prevention & control ; Public Health ; Records
Language	English
Publishing date	2023-09-26
Publishing country	Sweden
Document type	Journal Article
ZDB-ID	1338803-4
ISSN	1560-7917 ; 1025-496X
ISSN (online)	1560-7917
ISSN	1025-496X
DOI	10.2807/1560-7917.ES.2023.28.36.2300347
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Article ; Online: Disinfecting handheld electronic devices with UV-C in a healthcare setting.

Cremers-Pijpers, Suzan / van Rossum, Carsten / Dautzenberg, Mirjam / Wertheim, Heiman / Tostmann, Alma / Hopman, Joost

Infection prevention in practice

2021 Volume 3, Issue 2, Page(s) 100133

Abstract: Handheld Electronic Devices (HEDs) play a central role in the hospital environment. However, they can be a vehicle for transmitting (pathogenic) microorganisms. We studied whether disinfection with UV-C light is successful in disinfecting three different ...

Abstract	Handheld Electronic Devices (HEDs) play a central role in the hospital environment. However, they can be a vehicle for transmitting (pathogenic) microorganisms. We studied whether disinfection with UV-C light is successful in disinfecting three different HEDs in a clinical setting. Disinfection with UV-C light was performed with the UV-Smart® D25. We took a total of 800 samples on two departments and counted colony forming units. More than half of the baseline measurements were moderately (>10CFU) or highly (>50 CFU) contaminated. Post-disinfection the CFU was 0 in 87% of measurements. We conclude that the UV-Smart® D25 can be used to disinfect non-critical HEDs in clinical healthcare.
Language	English
Publishing date	2021-02-27
Publishing country	England
Document type	Journal Article
ISSN	2590-0889
ISSN (online)	2590-0889
DOI	10.1016/j.infpip.2021.100133
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Article ; Online: Outbreaks of healthcare-associated infections linked to water-containing hospital equipment: a literature review.

Yiek, Wing-Kee / Coenen, Olga / Nillesen, Mayke / van Ingen, Jakko / Bowles, Edmée / Tostmann, Alma

Antimicrobial resistance and infection control

2021 Volume 10, Issue 1, Page(s) 77

Abstract: Background: Healthcare-associated infections (HAIs) are a significant cause of morbidity and mortality in hospitalized patients. Water in the environment can be a source of infection linked to outbreaks and environmental transmission in hospitals. Water ...

Abstract	Background: Healthcare-associated infections (HAIs) are a significant cause of morbidity and mortality in hospitalized patients. Water in the environment can be a source of infection linked to outbreaks and environmental transmission in hospitals. Water safety in hospitals remains a challenge. This article has summarized available scientific literature to obtain an overview of outbreaks linked to water-containing hospital equipment and strategies to prevent such outbreaks. Methods: We made a list of water-containing hospital equipment and devices in which water is being used in a semi-closed circuit. A literature search was performed in PubMed with a search strategy containing the names of these medical devices and one or more of the following words: outbreak, environmental contamination, transmission, infection. For each medical device, we summarized the following information: the function of the medical device, causes of contamination, the described outbreaks and possible prevention strategies. Results: The following water-containing medical equipment or devices were identified: heater-cooler units, hemodialysis equipment, neonatal incubators, dental unit waterlines, fluid warmers, nebulizers, water traps, water baths, blanketrol, scalp cooling, and thermic stimulators. Of the latter three, no literature could be found. Of all other devices, one or more outbreaks associated with these devices were reported in the literature. Conclusions: The water reservoirs in water-containing medical devices can be a source of microbial growth and transmissions to patients, despite the semi-closed water circuit. Proper handling and proper cleaning and disinfection can help to reduce the microbial burden and, consequently, transmission to patients. However, these devices are often difficult to clean and disinfect because they cannot be adequately opened or disassembled, and the manufacturer's cleaning guidelines are often not feasible to execute. The development of equipment without water or fluid containers should be stimulated. Precise cleaning and disinfection guidelines and instructions are essential for instructing healthcare workers and hospital cleaning staff to prevent potential transmission to patients.
MeSH term(s)	Cross Infection/epidemiology ; Cross Infection/prevention & control ; Disease Outbreaks ; Disinfection/standards ; Equipment Contamination/prevention & control ; Equipment and Supplies, Hospital ; Humans ; Infection Control ; Water Supply
Language	English
Publishing date	2021-05-10
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2666706-X
ISSN	2047-2994 ; 2047-2994
ISSN (online)	2047-2994
ISSN	2047-2994
DOI	10.1186/s13756-021-00935-6
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Interventions to improve dispensing of antibiotics at the community level in low and middle income countries: a systematic review.

Afari-Asiedu, Samuel / Abdulai, Martha Ali / Tostmann, Alma / Boamah-Kaali, Ellen / Asante, Kwaku Poku / Wertheim, Heiman F L / Hulscher, Marlies

Journal of global antimicrobial resistance

2022 Volume 29, Page(s) 259–274

Abstract: Objectives: Inappropriate antibiotic dispensing is one of the key drivers of antibiotic resistance. This review documents the effectiveness of interventions aimed at improving antibiotic dispensing practices at the community level by drug dispensers in ... ...

Abstract	Objectives: Inappropriate antibiotic dispensing is one of the key drivers of antibiotic resistance. This review documents the effectiveness of interventions aimed at improving antibiotic dispensing practices at the community level by drug dispensers in low- and middle-income countries (LMIC). Methods: We conducted a systematic search in PubMed, EMBASE, Cochrane Central Register of Controlled Trials and Web of Science (11 November 2019). Studies were included if they reported data on the outcome measure: appropriate dispensing of medicine including antibiotics. The effectiveness of studies was assessed based on quantitative results reported in the studies included. Results: A total of 1158 articles were screened. Thirteen studies from Asia (six), Africa (five) and South America (one) and one study from both Africa and Asia were included in this review. Nine (69.2%) studies reported significant effectiveness of interventions on all or more than 50% of antibiotic-related outcomes. Cochrane Effective Practice and Organization of Care interventions frequently applied were educational meetings (9/13), distribution of educational materials (7/13), educational outreach meetings (7/13), reminders (6/13), local consensus processes (6/13), distribution of supplies (6/14) and clinical practice guidelines (4/14), Nine studies reported on stakeholder involvement. Conclusion: This review shows that it is possible to improve antibiotic dispensing practices at the community level in LMIC. Stakeholders' involvement was key in the design and implementation of interventions.
MeSH term(s)	Africa ; Anti-Bacterial Agents/therapeutic use ; Asia ; Developing Countries
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2022-03-25
Publishing country	Netherlands
Document type	Journal Article ; Review ; Systematic Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2710046-7
ISSN	2213-7173 ; 2213-7173
ISSN (online)	2213-7173
ISSN	2213-7173
DOI	10.1016/j.jgar.2022.03.009
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Article ; Online: The in situ efficacy of whole room disinfection devices: a literature review with practical recommendations for implementation.

van der Starre, Caroline M / Cremers-Pijpers, Suzan A J / van Rossum, Carsten / Bowles, Edmée C / Tostmann, Alma

Antimicrobial resistance and infection control

2022 Volume 11, Issue 1, Page(s) 149

Abstract: Background: Terminal cleaning and disinfection of hospital patient rooms must be performed after discharge of a patient with a multidrug resistant micro-organism to eliminate pathogens from the environment. Terminal disinfection is often performed ... ...

Abstract	Background: Terminal cleaning and disinfection of hospital patient rooms must be performed after discharge of a patient with a multidrug resistant micro-organism to eliminate pathogens from the environment. Terminal disinfection is often performed manually, which is prone to human errors and therefore poses an increased infection risk for the next patients. Automated whole room disinfection (WRD) replaces or adds on to the manual process of disinfection and can contribute to the quality of terminal disinfection. While the in vitro efficacy of WRD devices has been extensively investigated and reviewed, little is known about the in situ efficacy in a real-life hospital setting. In this review, we summarize available literature on the in situ efficacy of WRD devices in a hospital setting and compare findings to the in vitro efficacy of WRD devices. Moreover, we offer practical recommendations for the implementation of WRD devices. Methods: The in situ efficacy was summarized for four commonly used types of WRD devices: aerosolized hydrogen peroxide, H Results: In total, 54 articles were included. Articles reporting environmental outcomes of WRD devices had large variation in methodology, reported outcome measures, preparation of the patient room prior to environmental sampling, the location of sampling within the room and the moment of sampling. For the clinical outcome measures, all included articles reported the infection rate. Overall, these studies consistently showed that automated disinfection using any of the four types of WRD is effective in reducing environmental and clinical outcomes. Conclusion: Despite the large variation in the included studies, the four automated WRD systems are effective in reducing the amount of pathogens present in a hospital environment, which was also in line with conclusions from in vitro studies. Therefore, the assessment of what WRD device would be most suitable in a specific healthcare setting mostly depends on practical considerations.
MeSH term(s)	Humans ; Disinfection/methods ; Hydrogen Peroxide/pharmacology ; Ultraviolet Rays ; Patients' Rooms ; Xenon
Chemical Substances	Hydrogen Peroxide (BBX060AN9V) ; Xenon (3H3U766W84)
Language	English
Publishing date	2022-12-05
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2666706-X
ISSN	2047-2994 ; 2047-2994
ISSN (online)	2047-2994
ISSN	2047-2994
DOI	10.1186/s13756-022-01183-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Low SARS-CoV-2 Cq values in healthcare workers with symptomatic COVID-19 infections, regardless of symptom severity, The Netherlands, January to August 2022.

van Rossum, Carsten / Meijer, Corianne / van Weerdenburg, Ingrid Jm / Bowles, Edmée C / Rovers, Chantal P / Ten Oever, Jaap / Stol, Kim / van der Geest, Nannet Dj / McCall, Matthew B / Tostmann, Alma

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

2023 Volume 28, Issue 4

Abstract: We analysed SARS-CoV-2 PCR Cq values from 3,183 healthcare workers who tested positive between January and August 2022. Median Cq values were lower in symptomatic than in asymptomatic HCW. The difference in Cq values between HCW with mild vs moderate/ ... ...

Abstract	We analysed SARS-CoV-2 PCR Cq values from 3,183 healthcare workers who tested positive between January and August 2022. Median Cq values were lower in symptomatic than in asymptomatic HCW. The difference in Cq values between HCW with mild vs moderate/severe symptoms was statistically significant but negligibly small. To prevent nosocomial infections, all symptomatic HCW should be tested irrespective of symptom severity. This information can support decisions on testing and isolation, in the context of ongoing pressure on healthcare systems.
MeSH term(s)	Humans ; COVID-19/diagnosis ; SARS-CoV-2 ; Netherlands/epidemiology ; Health Personnel ; Cross Infection
Language	English
Publishing date	2023-01-26
Publishing country	Sweden
Document type	Journal Article
ZDB-ID	1338803-4
ISSN	1560-7917 ; 1025-496X
ISSN (online)	1560-7917
ISSN	1025-496X
DOI	10.2807/1560-7917.ES.2023.28.4.2300007
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Article ; Online: Field Epidemiology and Public Health Microbiology training: capturing the alumni perspectives of the training's impact.

Schaeffer, Justine / Hammer, Charlotte Christiane / Evlampidou, Iro / Bubba, Laura / Igloi, Zsofia / Dub, Timothée / Wendland, Annika / Whelan, Jane / Nielsen, Stine / Baidjoe, Amrish / Tostmann, Alma

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

2023 Volume 28, Issue 36

Abstract: We present the findings from the European Programme for Intervention Epidemiology Training (EPIET) Alumni Network (EAN) Member Survey conducted in October to December 2021. The EAN consists of field epidemiologists (EPIET) and public health ... ...

Abstract	We present the findings from the European Programme for Intervention Epidemiology Training (EPIET) Alumni Network (EAN) Member Survey conducted in October to December 2021. The EAN consists of field epidemiologists (EPIET) and public health microbiologists (European Public Health Microbiology Training Programme (EUPHEM)) who stay connected after their 2-year fellowship. This active alumni network provides opportunities for career development, mentorship, knowledge exchange and sharing of best practices for community members, affiliated professionals and public health organisations in Europe. Overall, 281 of 732 members participated in the survey. Of the 192 European fellowship alumni respondents, 173 (90%) indicated that skills and competencies acquired during their fellowship improved performance in their role compared with their abilities before the fellowship. Reported skills and competencies that could be further strengthened included data management/analysis, communication, mathematical modelling and leadership/team management. The EAN Member Survey provides valuable feedback to the EAN, as well as the fellowship programme offices at the European Centre for Disease Prevention and Control (ECDC) and affiliated field epidemiology programmes. The COVID-19 pandemic was a stark reminder of how essential cross-border collaborations are for continued European health security. Maintaining and increasing the professional, well-trained workforce remains crucial for optimal response to infectious diseases and protection of public health.
MeSH term(s)	Humans ; Public Health ; Pandemics ; COVID-19/epidemiology ; COVID-19/prevention & control ; Communication ; Europe/epidemiology
Language	English
Publishing date	2023-09-26
Publishing country	Sweden
Document type	Journal Article
ZDB-ID	1338803-4
ISSN	1560-7917 ; 1025-496X
ISSN (online)	1560-7917
ISSN	1025-496X
DOI	10.2807/1560-7917.ES.2023.28.36.2300388
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Disinfecting handheld electronic devices with UV-C in a healthcare setting

Suzan Cremers-Pijpers / Carsten van Rossum / Mirjam Dautzenberg / Heiman Wertheim / Alma Tostmann / Joost Hopman

Infection Prevention in Practice, Vol 3, Iss 2, Pp 100133- (2021)

2021

Abstract: Summary: Handheld Electronic Devices (HEDs) play a central role in the hospital environment. However, they can be a vehicle for transmitting (pathogenic) microorganisms. We studied whether disinfection with UV-C light is successful in disinfecting three ... ...

Abstract	Summary: Handheld Electronic Devices (HEDs) play a central role in the hospital environment. However, they can be a vehicle for transmitting (pathogenic) microorganisms. We studied whether disinfection with UV-C light is successful in disinfecting three different HEDs in a clinical setting. Disinfection with UV-C light was performed with the UV-Smart® D25. We took a total of 800 samples on two departments and counted colony forming units. More than half of the baseline measurements were moderately (>10CFU) or highly (>50 CFU) contaminated. Post-disinfection the CFU was 0 in 87% of measurements. We conclude that the UV-Smart® D25 can be used to disinfect non-critical HEDs in clinical healthcare.
Keywords	UV-C disinfection ; Handheld electronic devices ; Bacterial contamination ; Infectious and parasitic diseases ; RC109-216 ; Public aspects of medicine ; RA1-1270
Language	English
Publishing date	2021-06-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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