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  1. Article ; Online: Chao Nang Qing prescription promotes granulosa cell apoptosis and autophagy by targeting GATA3.

    Luo, Lan / Shen, Yan / Ning, Donghong / Tang, Mi / Xie, Licen / Zheng, Qiuman / Ouyang, Ziting

    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology

    2023  Volume 39, Issue 1, Page(s) 2223724

    Abstract: ... of Chao Nang Qing prescription (CNQP) in PCOS.: Methods: CNQP-medicated serum was prepared ...

    Abstract Objective: Polycystic ovary syndrome (PCOS) is a common endocrine disease in women of reproductive age, with complex pathological symptoms and mechanisms. This study explored the mechanism of action of Chao Nang Qing prescription (CNQP) in PCOS.
    Methods: CNQP-medicated serum was prepared for culturing KGN granulosa cells. GATA3 knockdown, MYCT1 overexpression, and MYCT1 knockdown vectors were constructed to transfect KGN cells. Cell proliferation and apoptosis, as well as the expression of autophagy-related LC3-II/I, Beclin-1, and p62, were analyzed. ChIP was used to detect the binding of GATA3 and the MYCT1 promoter, and dual-luciferase reporter assay was used to analyze the influence of GATA3 on MYCT1 promoter activity.
    Results: CNQP treatment reduced proliferation, increased apoptosis, elevated LC3-II/I, Beclin-1, GATA3, and MYCT1 expression, and decreased p62 expression in KGN cells. GATA3 bound to the MYCT1 promoter to promote MYCT1 expression. MYCT1 overexpression impeded proliferation and stimulated apoptosis and autophagy in KGN cells. Compared to CNQP treatment alone, GATA3 or MYCT1 knockdown before CNQP treatment promoted proliferation and reduced apoptosis and autophagy in KGN cells.
    Conclusion: CNQP may modulate KGN cell activity by upregulating GATA3 and MYCT1 expression, thereby slowing down the progression of PCOS.
    MeSH term(s) Humans ; Female ; MicroRNAs/metabolism ; Beclin-1/metabolism ; Granulosa Cells/metabolism ; Polycystic Ovary Syndrome/metabolism ; Cell Proliferation ; Apoptosis ; GATA3 Transcription Factor/genetics ; GATA3 Transcription Factor/metabolism ; GATA3 Transcription Factor/therapeutic use ; Nuclear Proteins
    Chemical Substances MicroRNAs ; Beclin-1 ; GATA3 protein, human ; GATA3 Transcription Factor ; MYCT1 protein, human ; Nuclear Proteins
    Language English
    Publishing date 2023-06-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 639237-4
    ISSN 1473-0766 ; 0951-3590
    ISSN (online) 1473-0766
    ISSN 0951-3590
    DOI 10.1080/09513590.2023.2223724
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: Fu chan ke chao yin bo xue

    Zheng, Chengjie

    (Zhonghua Minguo yi yong chao yin bo xue hui cong shu)

    2007  

    Author's details Zheng Chengjie zhu bian
    Series title Zhonghua Minguo yi yong chao yin bo xue hui cong shu
    MeSH term(s) Female Urogenital Diseases/diagnostic imaging ; Pregnancy Complications/diagnostic imaging ; Ultrasonography
    Language Chinese
    Size 537 p. :, ill.
    Edition Di 1 ban.
    Publisher Yi xuan tu shu fa xing
    Publishing place Taibei Xian, Xindian Shi
    Document type Book
    ISBN 9789576169106 ; 9576169100
    Database Catalogue of the US National Library of Medicine (NLM)

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  3. Book: Chu ci yu chao xian gu dai wen xue zhi guan lian yan jiu

    Zheng, Rinan

    (Chaoxian--Hanguo xue yan jiu cong shu)

    2012  

    Author's details Zheng ri nan zhu
    Series title Chaoxian--Hanguo xue yan jiu cong shu
    Language Chinese
    Size 3, 3, 283 p, 24 cm
    Edition Di 1 ban
    Publisher Ren min chu ban she
    Publishing place Bei jing
    Document type Book
    Note Includes bibliographical references (page 277-282)
    ISBN 7010106592 ; 9787010106595
    Database Former special subject collection: coastal and deep sea fishing

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  4. Book ; Online: Information Theory and Machine Learning

    Zheng, Lizhong / Tian, Chao / Tian, Chao

    2022  

    Keywords Technology: general issues ; History of engineering & technology ; supervised classification ; independent and non-identically distributed features ; analytical error probability ; empirical risk ; generalization error ; K-means clustering ; model compression ; population risk ; rate distortion theory ; vector quantization ; overfitting ; information criteria ; entropy ; model-based clustering ; merging mixture components ; component overlap ; interpretability ; time series prediction ; finite state machines ; hidden Markov models ; recurrent neural networks ; reservoir computers ; long short-term memory ; deep neural network ; information theory ; local information geometry ; feature extraction ; spiking neural network ; meta-learning ; information theoretic learning ; minimum error entropy ; artificial general intelligence ; closed-loop transcription ; linear discriminative representation ; rate reduction ; minimax game ; fairness ; HGR maximal correlation ; independence criterion ; separation criterion ; pattern dictionary ; atypicality ; Lempel-Ziv algorithm ; lossless compression ; anomaly detection ; information-theoretic bounds ; distribution and federated learning
    Language 0|e
    Size 1 electronic resource (254 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021620385
    ISBN 9783036553085 ; 3036553088
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Book: Liang qi chao qi meng si xiang de dong xue bei jing

    Zheng, Kuangmin

    (Zhong guo she hui ke xue yuan jin dai shi yan jiu suo zhuan kan ; 中国社会科学院近代史硏究所专刊)

    2003  

    Author's details Zheng kuang min zhu
    Series title Zhong guo she hui ke xue yuan jin dai shi yan jiu suo zhuan kan
    中国社会科学院近代史硏究所专刊
    Keywords Political science/Philosophy
    Language Chinese
    Size 2, 3, 3, 2, 288 p, 22 cm
    Edition Di 1 ban
    Publisher Shang hai shu dian chu ban she
    Publishing place Shang hai
    Document type Book
    Note Includes bibliographical references
    ISBN 7806780491 ; 9787806780497
    Database Former special subject collection: coastal and deep sea fishing

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  6. Book: Zhang bing lin, ou yang jing wu, liang qi chao, ma yi fu

    Zhang, Yufa / Ma, Tianxiang / Hu, Pingsheng / Zheng, Dahua

    (Zhong guo li dai si xiang jia ; 21 ; 中國歷代思想家 ; 21)

    1999  

    Institution 中華文化復興運動總會
    Author's details Zhang yu fa ... et al. zhu
    Series title Zhong guo li dai si xiang jia ; 21
    中國歷代思想家 ; 21
    Language Chinese
    Size 322 p, 21 cm
    Edition Geng xin ban
    Publisher Tai wan shang wu yin shu guan
    Publishing place Tai bei
    Document type Book
    ISBN 9570516224 ; 9789570516227
    Database Former special subject collection: coastal and deep sea fishing

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  7. Article ; Online: Quantum Simulation of Pseudo-Hermitian-

    Zheng, Chao

    Entropy (Basel, Switzerland)

    2022  Volume 24, Issue 7

    Abstract: Non-Hermitian (NH) quantum theory has been attracting increased research interest due to its featured properties, novel phenomena, and links to open and dissipative systems. Typical NH systems include PT-symmetric systems, pseudo-Hermitian systems, and ... ...

    Abstract Non-Hermitian (NH) quantum theory has been attracting increased research interest due to its featured properties, novel phenomena, and links to open and dissipative systems. Typical NH systems include PT-symmetric systems, pseudo-Hermitian systems, and their anti-symmetric counterparts. In this work, we generalize the pseudo-Hermitian systems to their complex counterparts, which we call
    Language English
    Publishing date 2022-06-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2014734-X
    ISSN 1099-4300 ; 1099-4300
    ISSN (online) 1099-4300
    ISSN 1099-4300
    DOI 10.3390/e24070867
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Unexpected toroidal micelles formed from St/MMA gradient copolymers.

    Zheng, Chao

    Soft matter

    2022  Volume 18, Issue 30, Page(s) 5706–5713

    Abstract: Toroidal micelles are of great interest and rarely observed in gradient copolymer systems. Herein, we report massive toroidal micelles formed from styrene (St)/methyl methacrylate (MMA) gradient copolymers using a common solvent mixing method followed by ...

    Abstract Toroidal micelles are of great interest and rarely observed in gradient copolymer systems. Herein, we report massive toroidal micelles formed from styrene (St)/methyl methacrylate (MMA) gradient copolymers using a common solvent mixing method followed by a cooling-heating procedure. Furthermore, we demonstrate that the obtained toroidal morphology is sensitively dependent on a heat treatment procedure. Solely spherical micelles are obtained by a common solvent mixing method. These spherical micelles could be transformed into toroidal micelles
    Language English
    Publishing date 2022-08-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2191476-X
    ISSN 1744-6848 ; 1744-683X
    ISSN (online) 1744-6848
    ISSN 1744-683X
    DOI 10.1039/d2sm00619g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: How to choose the suitable FNS specification in young patients with femoral neck fracture: A finite element analysis- letter to editor.

    Chao, Ting-Hsuan / Zheng, Zhi-Hong

    Injury

    2023  Volume 54, Issue 3, Page(s) 1012

    MeSH term(s) Humans ; Finite Element Analysis ; Femoral Neck Fractures ; Stress, Mechanical ; Fracture Fixation, Internal ; Femur Neck
    Language English
    Publishing date 2023-01-03
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 218778-4
    ISSN 1879-0267 ; 0020-1383
    ISSN (online) 1879-0267
    ISSN 0020-1383
    DOI 10.1016/j.injury.2023.01.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Predictive Value of the CHA

    Wu, Yaxin / Gao, Yanxiang / Li, Qing / Wu, Chao / Xie, Enmin / Tu, Yimin / Guo, Ziyu / Ye, Zixiang / Li, Peizhao / Li, Yike / Yu, Xiaozhai / Ren, Jingyi / Zheng, Jingang

    Frontiers in cardiovascular medicine

    2022  Volume 9, Page(s) 790193

    Abstract: ... of coronary artery disease and a high risk of cardiovascular events. The present study assessed the value of the CHA ... from January 2015 to May 2020. The CHA: Results: A total of 313 eligible patients were included in the study ... with a mean CHA: Conclusion: The CHA ...

    Abstract Background: Chronic kidney disease (CKD) patients have a high prevalence of coronary artery disease and a high risk of cardiovascular events. The present study assessed the value of the CHA
    Methods: This was a retrospective cohort study that included CKD patients who were hospitalized for ACS from January 2015 to May 2020. The CHA
    Results: A total of 313 eligible patients were included in the study, with a mean CHA
    Conclusion: The CHA
    Language English
    Publishing date 2022-03-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2022.790193
    Database MEDical Literature Analysis and Retrieval System OnLINE

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