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  1. Book: Therapeutic Rhodium Complexes

    Hussain, Afzal / Wani, Waseem A. / Lone, Mushtaq Ahmad / Alajmi, Mohamed F.

    (SpringerBriefs in Molecular Science)

    2023  

    Abstract: This book describes the emergence and recent advances in the design and development of rhodium complexes as therapeutic agents. Different classes of anticancer rhodium complexes with particular emphasis on ligands containing nitrogen-oxygen donor atoms ... ...

    Author's details Dr. Afzal Hussain is an associate professor at the Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. He completed his Ph.D. in Chemistry at Jamia Millia Islamia, New Delhi, India. in 2010. He has worked as a postdoctoral fellow at Sultan Qaboos University, Muscat, Oman, and Aligarh Muslim University, Aligarh, India. Having been admitted as a member to the Royal Society of Chemistry (MRSC) in 2018, he has 12 years of experience in teaching and research. His areas of research include separation science, bioanalysis, drug analysis, cosmeceutical analysis, nutraceutical analysis, and synthesis of novel nanomaterials as drug delivery carriers. Dr. Hussain completed a research project as a co-investigator entitled "Synthesis and Characterization of Novel Metal-Based Anticancer Drugs" Grant No: ¿ ¿- 36 - 227 Funded by KACST, Riyadh. Prof. Mohamed Fahad AlAjmi is the head of the Skills Development Unit at the Department of Pharmacognosy, College o
    Series title SpringerBriefs in Molecular Science
    Abstract This book describes the emergence and recent advances in the design and development of rhodium complexes as therapeutic agents. Different classes of anticancer rhodium complexes with particular emphasis on ligands containing nitrogen-oxygen donor atoms are presented. Anticancer rhodium complexes of N-heterocyclic carbenes are described, while half-sandwich, heterobimetallic, and multinuclear rhodium complexes are discussed. Therapeutic applications of rhodium complexes beyond cancer such as a...
    Keywords N-heterocyclic carbene ligands ; Anticancer rhodium complexes ; Half sandwich rhodium complexes ; DNA interacting agents ; Antibacterial agents ; Bioinorganic Chemistry ; Bioinorganic chemistry
    Language English
    Size 88 p.
    Edition 1
    Publisher Springer International Publishing
    Document type Book
    Note PDA Manuell_21
    Format 155 x 235 x 5
    ISBN 9783031356308 ; 3031356306
    Database PDA

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  2. Article ; Online: Dengue Cases Presenting to the Emergency Department of a Tertiary Care Hospital in Late 2021: A Cross-Sectional Study in Karachi.

    Mushtaq, Saima / Abro, Muhammad Tarish / Hussain, Hassan Ul

    International journal of public health

    2024  Volume 69, Page(s) 1606753

    Abstract: Objectives: ...

    Abstract Objectives:
    MeSH term(s) Male ; Female ; Humans ; Dengue/epidemiology ; Cross-Sectional Studies ; Tertiary Care Centers ; Retrospective Studies ; Pandemics ; Fever/epidemiology ; COVID-19/epidemiology ; Emergency Service, Hospital
    Language English
    Publishing date 2024-02-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2274130-6
    ISSN 1661-8564 ; 1661-8556
    ISSN (online) 1661-8564
    ISSN 1661-8556
    DOI 10.3389/ijph.2024.1606753
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  3. Article: Psychosocial Aspects of Rheumatic Disease Management: Addressing Mental Health and Well-Being.

    Bokhari, Syed Faqeer Hussain / Mushtaq, Aqsa

    Cureus

    2023  Volume 15, Issue 11, Page(s) e49267

    Abstract: Rheumatic disease imposes a substantial emotional burden on individuals, leading to chronic pain, discomfort, anxiety, and depression. Coping with unpredictability and physical limitations can create a detrimental feedback loop, exacerbating mental and ... ...

    Abstract Rheumatic disease imposes a substantial emotional burden on individuals, leading to chronic pain, discomfort, anxiety, and depression. Coping with unpredictability and physical limitations can create a detrimental feedback loop, exacerbating mental and physical symptoms. Poor mental health can hinder treatment adherence and worsen disease progression. Addressing the emotional impact of rheumatic disease is crucial for comprehensive management. Healthcare providers play a critical role in recognizing psychosocial concerns through attentive listening and standardized screenings. Open communication and a collaborative approach lead to more effective care. Support systems involving family, friends, and support groups provide emotional help and reduce isolation. Coping strategies and self-management techniques empower patients to navigate their conditions. The stigma associated with mental health is a challenge that requires education, awareness, and patient advocacy. A multidisciplinary approach integrating mental health services is pivotal for addressing the psychosocial aspects of rheumatic disease, offering a holistic perspective. Ongoing research explores the interplay between mental health and physical symptoms, aiming for innovative therapies and improved patient care. Collaborative care models and patient advocacy are essential to reducing barriers and improving patient outcomes. The future of rheumatic disease management lies in a patient-centered, multidisciplinary approach that addresses both physical and mental aspects.
    Language English
    Publishing date 2023-11-22
    Publishing country United States
    Document type Editorial
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.49267
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  4. Article: Impact of transformational leadership intervention of head nurses among front-line soldiers (staff nurses) working in government hospital.

    Mushtaq, Khudija / Hussain, Muhammad / Parveen, Kousar

    JPMA. The Journal of the Pakistan Medical Association

    2023  Volume 72, Issue 10, Page(s) 1998–2002

    Abstract: Objective: To assess the impact of transformational leadership intervention among head nurses on staff nurses in improving job performance.: Method: The quasi-experimental study was conducted from December 2020 to August 2021 at the public-sector ... ...

    Abstract Objective: To assess the impact of transformational leadership intervention among head nurses on staff nurses in improving job performance.
    Method: The quasi-experimental study was conducted from December 2020 to August 2021 at the public-sector Services Hospital, Lahore, Pakistan, and comprised head nurses and staff nurses enrolled through multistage cluster random sampling technique. Sixteen weeks of transformational leadership interventions were organised in morning and evening shifts. Pre- and post-intervention assessments were done. Data was analysed using SPSS 25.
    Results: Of the 576 subjects, 480(83.3%) were staff nurses and 96(16.6%) were head nurses. Transformational leadership intervention caused a significant improvement in staff nurses' job performance owing to improvement in the behaviour of the head nurses behaviour (p<0.05).
    Conclusions: The study showed that staff nurses' performance significantly improved after transformational.
    MeSH term(s) Humans ; Leadership ; Nursing, Supervisory ; Military Personnel ; Job Satisfaction ; Nursing Staff, Hospital ; Hospitals, Public ; Government ; Nurses ; Surveys and Questionnaires
    Language English
    Publishing date 2023-01-24
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    DOI 10.47391/JPMA.4167
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  5. Article ; Online: Ultrasonically assisted hydrothermal synthesis of tungsten(VI) oxide-TiO

    Shah, Aarif Hussain / Rather, Mushtaq Ahmad

    Environmental science and pollution research international

    2023  Volume 30, Issue 41, Page(s) 93916–93933

    Abstract: Photocatalytic degradation of pharmaceutical residues through natural solar radiation represents a green and economical treatment process. In this work, ultrasonically assisted hydrothermal synthesis of ... ...

    Abstract Photocatalytic degradation of pharmaceutical residues through natural solar radiation represents a green and economical treatment process. In this work, ultrasonically assisted hydrothermal synthesis of WO
    MeSH term(s) Sunlight ; Oxides/chemistry ; Acetaminophen ; Tungsten ; Titanium/chemistry ; Catalysis ; Nanocomposites/chemistry ; Light
    Chemical Substances Oxides ; titanium dioxide (15FIX9V2JP) ; Acetaminophen (362O9ITL9D) ; Tungsten (V9306CXO6G) ; Titanium (D1JT611TNE)
    Language English
    Publishing date 2023-07-31
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-28928-5
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  6. Article ; Online: Role of successive round as a quality signal in equity crowdfunding: Novel evidence from the perspective of investors' preferences.

    Wasti, Syed Muhammad Hamza Abid / Ahmed, Jaleel / Khan, Mushtaq Hussain

    PloS one

    2024  Volume 19, Issue 3, Page(s) e0297820

    Abstract: Equity crowdfunding provides entrepreneurs and founders the opportunity to raise funds from a large number of potential investors, using quality signals to influence their investment decisions. Drawing from the lens of signaling theory and the ... ...

    Abstract Equity crowdfunding provides entrepreneurs and founders the opportunity to raise funds from a large number of potential investors, using quality signals to influence their investment decisions. Drawing from the lens of signaling theory and the elaboration likelihood model, this study explores the role of successive equity crowdfunding rounds as a quality signal in shaping investors' preferences in crowdfunded firms and its influence on their investment decisions. Our findings reveal that successive equity crowdfunding rounds serve as quality signals, modeling investors' preferences and thereby resulting in a high magnitude of success factors. The successive round is a strong quality signal that has a positive and significant impact on investors' investment decisions in subsequent equity crowdfunding rounds. The increasing preferences of investors due to the successive round augments the magnitude of success factors and helps entrepreneurs in successfully achieving large funding targets, high overfunding, and attracting a large number of investors in subsequent equity crowdfunding campaigns, even with a low level of equity offering.
    MeSH term(s) Investments ; Probability
    Language English
    Publishing date 2024-03-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0297820
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  7. Article ; Online: RAS

    Mustansar, Tazeen / Mirza, Talat / Hussain, Mushtaq

    Biotechnic & histochemistry : official publication of the Biological Stain Commission

    2023  Volume 98, Issue 6, Page(s) 382–390

    Abstract: Members of ... ...

    Abstract Members of the
    MeSH term(s) Humans ; Carcinoma, Squamous Cell/genetics ; Genes, ras ; Head and Neck Neoplasms/genetics ; Mouth Neoplasms/genetics ; Mutation ; Proto-Oncogene Proteins p21(ras)/genetics ; Squamous Cell Carcinoma of Head and Neck/genetics
    Chemical Substances Proto-Oncogene Proteins p21(ras) (EC 3.6.5.2)
    Language English
    Publishing date 2023-04-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 1069349-x
    ISSN 1473-7760 ; 1052-0295
    ISSN (online) 1473-7760
    ISSN 1052-0295
    DOI 10.1080/10520295.2023.2196731
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  8. Article: Gemistocytic Differentiation in Isocitrate Dehydrogenase Mutant Astrocytomas: A Histopathological and Survival Analysis.

    Hassan, Usman / Amer, Faizan / Hussain, Mudassar / Mushtaq, Sajid / Loya, Asif / Abu Bakar, Muhammad

    Cureus

    2023  Volume 15, Issue 4, Page(s) e37542

    Abstract: Gemistocytic differentiation is a rare histological feature seen in IDH mutant Astrocytomas. The 2021 World Health Organization (WHO) retains the diagnosis of IDH mutant Astrocytoma with its classical histology and tumors with the rare histological ... ...

    Abstract Gemistocytic differentiation is a rare histological feature seen in IDH mutant Astrocytomas. The 2021 World Health Organization (WHO) retains the diagnosis of IDH mutant Astrocytoma with its classical histology and tumors with the rare histological pattern of g
    Language English
    Publishing date 2023-04-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.37542
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  9. Article: [Profiling of Targeted miRNAs (8-nt) for the Genes Involved in Type 2 Diabetes Mellitus and Cardiac Hypertrophy].

    Hussain, K / Ishtiaq, A / Mushtaq, I / Murtaza, I

    Molekuliarnaia biologiia

    2022  Volume 57, Issue 2, Page(s) 360–361

    Abstract: Type 2 Diabetes Mellitus (T2DM) and cardiac hypertrophy (CH) are among the top ten leading cause of deaths, worldwide. T2DM and cardiac hypertrophy are the chronic diseases, have close association and direct life-threatening complications like stroke, ... ...

    Abstract Type 2 Diabetes Mellitus (T2DM) and cardiac hypertrophy (CH) are among the top ten leading cause of deaths, worldwide. T2DM and cardiac hypertrophy are the chronic diseases, have close association and direct life-threatening complications like stroke, myocardial infarction, retinopathy, nephropathy, and limb amputation. In addition to other medical approaches, miRNAs-based strategy is considered most efficient for early detection of chronic diseases and also has potential for the treatment of T2DM and cardiac hypertrophy like it is being used for cancer in clinical trials. MicroRNAs (miRNAs) are single stranded (non-coding) of 20 to 22 nucleotides sequences which bind to their target mRNA upon the complimentary basis, to silence the protein expression at post transcriptional level. Bioinformatic databases are used like online mendelian inheritance in man (OMIM), gene testing registry (GTR), TargetScan and ShinyGO for validation of disease linked genes and sorting the common miRNAs in both diseases, such as miR-30-5p/101-3p.2/190-5p/506-3p/9-5p/128-3p/137/96-5p/7-5p/107/101-3p.1/98-5p/124-3p.2/124-3p.116-5p/15-5p/497-5p/ 424-5p/195-5p/1271-5p, let-7-5p. Aforementioned databases were also used for the miRNAs which have more than one disease linked genes target in each pathological condition. Such miRNAs for cardiac hypertrophy are: miR-19-3p/183-5p.2/153-3p/372-3p/302-3p/520-3p/373-3p/129-5p/144-3p/139-5p and for T2DM are: miR-27-3p/206/1-3p/181-5p. This finding would be helpful for the appropriate selection of miRNAs and to design applicable research project in future. It will require more validation by using the miRNAs expression analysis, mimic, and anti-miRNA approach to check their potential against cardiac hypertrophy and T2DM.
    MeSH term(s) Humans ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Diabetes Mellitus, Type 2/genetics ; Cardiomegaly/genetics ; Gene Expression Profiling
    Chemical Substances MicroRNAs
    Language Russian
    Publishing date 2022-06-13
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article
    ZDB-ID 213542-5
    ISSN 0026-8984
    ISSN 0026-8984
    DOI 10.31857/S0026898423020088, EDN: EEGWYK
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  10. Article: Pharmacological effect of

    Rasool, Naeem / Omer, Muhammad Ovais / Javeed, Aqeel / Nawaz, Muhammad / Imran, Muhammad / Hussain, Muzzamal / Mushtaq, Zarina / Al Jbawi, Entessar

    Food science & nutrition

    2023  Volume 11, Issue 10, Page(s) 6312–6323

    Abstract: Argyrolobium ... ...

    Abstract Argyrolobium roseum
    Language English
    Publishing date 2023-07-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2703010-6
    ISSN 2048-7177
    ISSN 2048-7177
    DOI 10.1002/fsn3.3570
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