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  1. Book ; Online: Passive Planar Microwave Devices

    Fernandez-Prieto, Armando / Fernandez-Prieto, Armando / Martinez-Ros, Alejandro Javier

    2022  

    Keywords Technology: general issues ; History of engineering & technology ; microwave tunable phase shifters ; 3 dB/90° coupler ; K band ; HD ; MSP ; RF ; SVM ; wireless sensing technology ; antenna design ; constrained optimization problems ; coral reefs optimization algorithm ; meta-heuristics ; antenna ; MIMO ; octagonal ; planar ; UWB ; vivaldi antenna ; miniaturized ; high gain ; surface plasmons ; ultrawideband ; microwave sensor ; differential sensor ; dielectric characterization ; microfluidics ; electrically small resonators ; biosensors ; dual-band differential filter ; common-mode suppression ; magnetic coupling ; multilayer structure ; glide symmetry ; higher symmetries ; Maxwell fish-eye lens ; metasurface ; periodic structures ; printed circuit board ; coplanar waveguides ; vehicular networks ; IEEE 802.11p ; indium-tin oxide (ITO) ; transparent antenna ; bandpass filter ; discriminating coupling ; high selectivity ; source-load coupling ; plasma diagnostics ; electron density measurement ; planar microwave cutoff probe ; bar-type cutoff probe ; ring-type cutoff probe ; computational characterization ; substrate integrated waveguide ; ridge waveguide ; tapering structure ; broadband ; microwave devices ; n/a
    Language 0|e
    Size 1 electronic resource (180 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021619468
    ISBN 9783036544960 ; 3036544968
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Surgical Treatment in Post-Stroke Spastic Hands: A Systematic Review.

    Hurtado-Olmo, Patricia / González-Santos, Ángela / Pérez de Rojas, Javier / Fernández-Martínez, Nicolás Francisco / Del Olmo, Laura / Hernández-Cortés, Pedro

    Journal of clinical medicine

    2024  Volume 13, Issue 4

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2024-02-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13040945
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Prostaglandin Transporter and Dipeptidyl Peptidase-4 as New Pharmacological Targets in the Prevention of Acute Kidney Injury in Diabetes: An In Vitro Study.

    Gallego-Tamayo, Beatriz / Santos-Aparicio, Ángela / Yago-Ibáñez, Julia / Muñoz-Moreno, Laura / Lucio-Cazaña, Francisco Javier / Fernández-Martínez, Ana B

    International journal of molecular sciences

    2024  Volume 25, Issue 6

    Abstract: The probability of acute kidney injury (AKI) is higher in septic diabetic patients, which is associated with, among other factors, proximal tubular cell (PTC) injury induced by the hypoxic/hyperglycemic/inflammatory microenvironment that surrounds PTCs ... ...

    Abstract The probability of acute kidney injury (AKI) is higher in septic diabetic patients, which is associated with, among other factors, proximal tubular cell (PTC) injury induced by the hypoxic/hyperglycemic/inflammatory microenvironment that surrounds PTCs in these patients. Here, we exposed human PTCs (HK-2 cells) to 1% O
    MeSH term(s) Humans ; Cyclooxygenase 2/metabolism ; Diabetes Mellitus/drug therapy ; Acute Kidney Injury/drug therapy ; Acute Kidney Injury/etiology ; Acute Kidney Injury/prevention & control ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases ; Prostaglandins ; Dipeptidyl-Peptidase IV Inhibitors/pharmacology ; Dipeptidyl-Peptidase IV Inhibitors/therapeutic use ; Dipeptidyl Peptidase 4
    Chemical Substances Cyclooxygenase 2 (EC 1.14.99.1) ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases (EC 3.4.14.-) ; Prostaglandins ; Dipeptidyl-Peptidase IV Inhibitors ; Dipeptidyl Peptidase 4 (EC 3.4.14.5)
    Language English
    Publishing date 2024-03-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25063345
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Best Nursing Practice: Safe and Inclusive Healthcare Environments for Transgender People: A Systematic Review.

    García-Acosta, Jesús Manuel / Castro-Molina, Francisco Javier / Fernández-Martínez, Alfredo David / Delgado-Reyes, Airam / Castellano-Fuenmayor, María Andreína

    Nursing reports (Pavia, Italy)

    2024  Volume 14, Issue 1, Page(s) 287–302

    Abstract: 1) Background: The aim of this study was to review the scope of the existing scientific literature on creating safe and inclusive healthcare environments for transgender people and provide an overview of the resources and nursing skills required to do ... ...

    Abstract (1) Background: The aim of this study was to review the scope of the existing scientific literature on creating safe and inclusive healthcare environments for transgender people and provide an overview of the resources and nursing skills required to do so. (2) Methods: With the research question in mind, an exploratory search of six databases was conducted to identify all relevant primary studies. After screening and selection of articles based on the inclusion and exclusion criteria, a total of 41 articles were included and reviewed. (3) Results: The results were classified under four headings: the training of health professionals, the creation of safe spaces, the nurse as facilitator, and best care practice. Most of the evidence indicates that it is essential for nurses and other healthcare staff to be trained in specific skills to provide comprehensive, high-quality care to transgender people; however, there is a lack of material and human resources to do so. (4) Conclusions: The trans-inclusive care competent nurse should use neutral language that respects the person's preferred name and pronouns in a safe healthcare environment that offers and ensures warmth, respect, and inclusivity in the care provided. This study was registered with the Open Science Framework (OSF) on 9 January 2024 (osf.io/rpj6a).
    Language English
    Publishing date 2024-01-25
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2039-4403
    ISSN (online) 2039-4403
    DOI 10.3390/nursrep14010022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Reducing the Impact of Sensor Orientation Variability in Human Activity Recognition Using a Consistent Reference System.

    Gil-Martín, Manuel / López-Iniesta, Javier / Fernández-Martínez, Fernando / San-Segundo, Rubén

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 13

    Abstract: Sensor- orientation is a critical aspect in a Human Activity Recognition (HAR) system based on tri-axial signals (such as accelerations); different sensors orientations introduce important errors in the activity recognition process. This paper proposes a ...

    Abstract Sensor- orientation is a critical aspect in a Human Activity Recognition (HAR) system based on tri-axial signals (such as accelerations); different sensors orientations introduce important errors in the activity recognition process. This paper proposes a new preprocessing module to reduce the negative impact of sensor-orientation variability in HAR. Firstly, this module estimates a consistent reference system; then, the tri-axial signals recorded from sensors with different orientations are transformed into this consistent reference system. This new preprocessing has been evaluated to mitigate the effect of different sensor orientations on the classification accuracy in several state-of-the-art HAR systems. The experiments were carried out using a subject-wise cross-validation methodology over six different datasets, including movements and postures. This new preprocessing module provided robust HAR performance even when sudden sensor orientation changes were included during data collection in the six different datasets. As an example, for the WISDM dataset, sensors with different orientations provoked a significant reduction in the classification accuracy of the state-of-the-art system (from 91.57 ± 0.23% to 89.19 ± 0.26%). This important reduction was recovered with the proposed algorithm, increasing the accuracy to 91.46 ± 0.30%, i.e., the same result obtained when all sensors had the same orientation.
    MeSH term(s) Humans ; Human Activities ; Algorithms ; Acceleration ; Movement ; Posture
    Language English
    Publishing date 2023-06-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23135845
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: N-Type Ca Channel in Epileptic Syndromes and Epilepsy: A Systematic Review of Its Genetic Variants.

    Mayo, Sonia / Gómez-Manjón, Irene / Marco-Hernández, Ana Victoria / Fernández-Martínez, Francisco Javier / Camacho, Ana / Martínez, Francisco

    International journal of molecular sciences

    2023  Volume 24, Issue 7

    Abstract: N-type voltage-gated calcium channel controls the release of neurotransmitters from neurons. The association of other voltage-gated calcium channels with epilepsy is well-known. The association of N-type voltage-gated calcium channels and pain has also ... ...

    Abstract N-type voltage-gated calcium channel controls the release of neurotransmitters from neurons. The association of other voltage-gated calcium channels with epilepsy is well-known. The association of N-type voltage-gated calcium channels and pain has also been established. However, the relationship between this type of calcium channel and epilepsy has not been specifically reviewed. Therefore, the present review systematically summarizes existing publications regarding the genetic associations between N-type voltage-dependent calcium channel and epilepsy.
    MeSH term(s) Humans ; Calcium/metabolism ; Calcium Channels, N-Type ; Epilepsy/genetics ; Epileptic Syndromes ; Neurons/metabolism
    Chemical Substances Calcium (SY7Q814VUP) ; Calcium Channels, N-Type
    Language English
    Publishing date 2023-03-23
    Publishing country Switzerland
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24076100
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Affinity Isolation of Endogenous Saccharomyces Cerevisiae Nuclear Pore Complexes.

    Nudelman, Ilona / Fernandez-Martinez, Javier / Rout, Michael P

    Methods in molecular biology (Clifton, N.J.)

    2022  Volume 2502, Page(s) 3–34

    Abstract: Studying protein complexes in vitro requires the production of a relatively pure sample that maintains the full complement, native organization, and function of that complex. This can be particularly challenging to achieve for large, multi-component, ... ...

    Abstract Studying protein complexes in vitro requires the production of a relatively pure sample that maintains the full complement, native organization, and function of that complex. This can be particularly challenging to achieve for large, multi-component, membrane embedded complexes using the traditional recombinant expression and reconstitution methodologies. However, using affinity capture from native cells, suitable whole endogenous protein complexes can be isolated. Here we present a protocol for the affinity isolation of baker's yeast (S. cerevisiae) nuclear pore complexes, which are ~50 MDa assemblies made up of 552 distinct proteins and embedded in a double-membraned nuclear envelope. Producing this sample allowed us for the first time to perform analyses to characterize the mass, stoichiometry, morphology, and connectivity of this complex and to obtain its integrative structure with ~9 Å precision. We believe this methodology can be applied to other challenging protein complexes to produce similar results.
    MeSH term(s) Nuclear Envelope/metabolism ; Nuclear Pore/metabolism ; Nuclear Pore Complex Proteins/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/metabolism
    Chemical Substances Nuclear Pore Complex Proteins ; Saccharomyces cerevisiae Proteins
    Language English
    Publishing date 2022-04-12
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-2337-4_1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Exploring the Metabolic Differences between Cisplatin- and UV Light-Induced Apoptotic Bodies in HK-2 Cells by an Untargeted Metabolomics Approach.

    Bernardo-Bermejo, Samuel / Sánchez-López, Elena / Castro-Puyana, María / Fernández-Martínez, Ana B / Lucio-Cazaña, Francisco Javier / Marina, María Luisa

    International journal of molecular sciences

    2023  Volume 24, Issue 8

    Abstract: Among the extracellular vesicles, apoptotic bodies (ABs) are only formed during the apoptosis and perform a relevant role in the pathogenesis of different diseases. Recently, it has been demonstrated that ABs from human renal proximal tubular HK-2 cells, ...

    Abstract Among the extracellular vesicles, apoptotic bodies (ABs) are only formed during the apoptosis and perform a relevant role in the pathogenesis of different diseases. Recently, it has been demonstrated that ABs from human renal proximal tubular HK-2 cells, either induced by cisplatin or by UV light, can lead to further apoptotic death in naïve HK-2 cells. Thus, the aim of this work was to carry out a non-targeted metabolomic approach to study if the apoptotic stimulus (cisplatin or UV light) affects in a different way the metabolites involved in the propagation of apoptosis. Both ABs and their extracellular fluid were analyzed using a reverse-phase liquid chromatography-mass spectrometry setup. Principal components analysis showed a tight clustering of each experimental group and partial least square discriminant analysis was used to assess the metabolic differences existing between these groups. Considering the variable importance in the projection values, molecular features were selected and some of them could be identified either unequivocally or tentatively. The resulting pathways indicated that there are significant, stimulus-specific differences in metabolites abundancies that may propagate apoptosis to healthy proximal tubular cells; thus, we hypothesize that the share in apoptosis of these metabolites might vary depending on the apoptotic stimulus.
    MeSH term(s) Humans ; Cisplatin/pharmacology ; Ultraviolet Rays ; Metabolomics/methods ; Apoptosis ; Extracellular Vesicles
    Chemical Substances Cisplatin (Q20Q21Q62J)
    Language English
    Publishing date 2023-04-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24087237
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Epidemiology of human papillomavirus-associated anogenital cancers in Granada: a three-decade population-based study.

    Dabán-López, Pablo / Fernández-Martínez, Nicolás Francisco / Petrova, Dafina / Rodríguez-Barranco, Miguel / Jiménez-Moleón, Jose Juan / Gutierrez, Javier / Sánchez, María-José

    Frontiers in public health

    2023  Volume 11, Page(s) 1205170

    Abstract: Introduction: HPV infection is a common risk factor for all anogenital cancers. However, there are important differences in the epidemiology of anogenital cancers and these have not been compared considering diverse epidemiological indicators over a ... ...

    Abstract Introduction: HPV infection is a common risk factor for all anogenital cancers. However, there are important differences in the epidemiology of anogenital cancers and these have not been compared considering diverse epidemiological indicators over a long period of time. To fill this gap, we investigated incidence, mortality, and survival trends of anogenital cancers over a period of three decades.
    Methods: We conducted an observational registry-based study using data from the population-based cancer registry of Granada in southern Spain. We collected data on all incident cases of anogenital cancer (cervical, anal, penile, vulvar, and vaginal cancer) diagnosed between 1985 and 2017. We calculated crude and age-standardized incidence and mortality rates, and 1, 3, and 5-year overall and net survival. We further conducted time-trend analysis calculating annual percent changes (APC) for each cancer site.
    Results: The incidence of anogenital cancers decreased slightly during the past 30 years, with the exception of vulvar cancer, where a slight increase was observed. Mortality decreased significantly for cervical cancer over the study period but increased non-significantly for the remaining cancer sites. Survival rates were similar to those reported in comparable countries and increased for cervical and vulvar cancer.
    Discussion: Cervical cancer was the greatest contributor to the burden of anogenital cancers and showed a marked improvement in all indicators in comparison to the remaining cancer sites.
    MeSH term(s) Female ; Humans ; Human Papillomavirus Viruses ; Uterine Cervical Neoplasms/epidemiology ; Vulvar Neoplasms/epidemiology ; Vulvar Neoplasms/complications ; Anus Neoplasms/epidemiology ; Anus Neoplasms/diagnosis ; Papillomavirus Infections/complications
    Language English
    Publishing date 2023-09-14
    Publishing country Switzerland
    Document type Observational Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2023.1205170
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The Effect of Studying a Double Degree in the Psychophysiological Stress Response in the Bachelor's Thesis Defense.

    Ramírez-Adrados, Ana / Fernández-Elías, Valentín E / Fernández-Martínez, Silvia / Martínez-Pascual, Beatriz / Gonzalez-de-Ramos, Cristina / Clemente-Suárez, Vicente Javier

    International journal of environmental research and public health

    2022  Volume 19, Issue 3

    Abstract: The aim of this research was to analyze the effect of studying a single or double degree in the psychophysiological stress response and academic performance of university students in their bachelor's thesis defense. We analyzed the autonomic stress ... ...

    Abstract The aim of this research was to analyze the effect of studying a single or double degree in the psychophysiological stress response and academic performance of university students in their bachelor's thesis defense. We analyzed the autonomic stress response, cortical arousal, subjective distress perception, and the sense of objective and subjective academic fulfilment of 84 single-degree physiotherapy students and 26 double-degree sport sciences and physiotherapy students during their bachelor's thesis defense. The results showed that the bachelor's thesis defense was a stressful event for double-degree students, showing an activation of the sympathetic nervous system and presenting a higher autonomic habituation response for the double degree students compared to the single degree students. We found higher mean grades during the whole degree and higher grades in the written and oral bachelor's thesis academic achievements for single-degree students compared to double-degree students. No significant differences were found between single-degree and double-degree students in subjective distress perception and cortical arousal. No correlation was found between academic performance variables and subjective distress perception, cortical arousal, and autonomic modulation variables. We conclude that the bachelor's thesis defense produces a large anticipatory anxiety response in single-degree physiotherapy students and in double-degree sport sciences and physiotherapy students. Double-degree students showed higher levels of habituation and adaptability to the stressful event, with a better autonomic response. Academic achievements were significantly higher among single-degree students compared to the double-degree group.
    MeSH term(s) Anxiety ; Autonomic Nervous System ; Humans ; Psychophysiology ; Students ; Writing
    Language English
    Publishing date 2022-01-21
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19031207
    Database MEDical Literature Analysis and Retrieval System OnLINE

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