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Article: Arsen u morskim ribama, rakovima i glavonoscima

Petrovic, I / Katalenic, M

Hrana i ishrana. = Food and nutrition. May/June 1981. v. 22 (5/6)

1981

Title translation	Arsenic in sea fish, crayfish and Cephalopoda.
Keywords	aquatic organisms ; food contamination
Language	Croatian
Dates of publication	1981-05
Size	p. 115-118., ill.
Document type	Article
Note	Summary in English.
ZDB-ID	273844-2
ISSN	0018-6872
ISSN	0018-6872
Database	NAL-Catalogue (AGRICOLA)

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Z 4835: Show issues

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Article ; Online: Acquired von Willebrand syndrome and post-operative drainage: a comparison of patients with aortic stenosis versus coronary artery disease.

Djordjevic, Aleksandar / Jovicic, Vladimir / Lazovic, Dejan / Terzic, Dusko / Gacic, Jasna / Petrovic, Masa / Matejic, Aleksandar / Salovic, Bojana / Radovic, Ivana / Jesic-Petrovic, Tanja / Ristic, Arsen / Soldatovic, Ivan

General thoracic and cardiovascular surgery

2024

Abstract: Objective: Degenerative aortic stenosis and coronary artery disease are considered to be the most prevalent cardiovascular diseases in industrialized countries. This study aims to determine the change over time in von Willebrand factor antigen, von ... ...

Abstract	Objective: Degenerative aortic stenosis and coronary artery disease are considered to be the most prevalent cardiovascular diseases in industrialized countries. This study aims to determine the change over time in von Willebrand factor antigen, von Willebrand factor activity, and factor VIII and where there is a correlation with total post-operative drainage. Methods: The single-center retrospective study included 203 consecutive patients (64.5% male), undergoing coronary artery bypass surgery between March 1, 2019 and June 30, 2020 at the University Clinical Center of Serbia in the Clinic for Cardiac Surgery in Belgrade, Serbia. All patients 18 years or older who presented with isolated, hemodynamically significant aortic stenosis were included. The control group consisted of patients who presented with only coronary artery disease. Results: Between patients with only coronary artery disease and patients with coronary artery diseases and aortic stenosis, there was a statistically significant difference between pre-op and 1-month post-op fibrinogen, factor VIII, von Willebrand factor antigen, and von Willebrand factor (p < 0.001), post-op drainage, with overall lower drainage in coronary artery disease patients, and consistent increase in von Willebrand factor antigen, von Willebrand factor activity, and Factor VIII post-operatively in patients with coronary artery diseases and aortic stenosis. Conclusion: This study has shown that there is a correlation between von Willebrand factor antigen, von Willebrand factor activity and total drainage to the level of statistical significance in aortic stenosis patients and in the overall study population.
Language	English
Publishing date	2024-01-27
Publishing country	Japan
Document type	Journal Article
ZDB-ID	2376888-5
ISSN	1863-6713 ; 1863-6705
ISSN (online)	1863-6713
ISSN	1863-6705
DOI	10.1007/s11748-023-02007-5
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Article ; Online: Vesicle condensation induced by synapsin: condensate size, geometry, and vesicle shape deformations.

Alfken, Jette / Neuhaus, Charlotte / Major, András / Taskina, Alyona / Hoffmann, Christian / Ganzella, Marcelo / Petrovic, Arsen / Zwicker, David / Fernández-Busnadiego, Rubén / Jahn, Reinhard / Milovanovic, Dragomir / Salditt, Tim

The European physical journal. E, Soft matter

2024 Volume 47, Issue 1, Page(s) 8

Abstract: We study the formation of vesicle condensates induced by the protein synapsin, as a cell-free model system mimicking vesicle pool formation in the synapse. The system can be considered as an example of liquid-liquid phase separation (LLPS) in ... ...

Abstract	We study the formation of vesicle condensates induced by the protein synapsin, as a cell-free model system mimicking vesicle pool formation in the synapse. The system can be considered as an example of liquid-liquid phase separation (LLPS) in biomolecular fluids, where one phase is a complex fluid itself consisting of vesicles and a protein network. We address the pertinent question why the LLPS is self-limiting and stops at a certain size, i.e., why macroscopic phase separation is prevented. Using fluorescence light microscopy, we observe different morphologies of the condensates (aggregates) depending on the protein-to-lipid ratio. Cryogenic electron microscopy then allows us to resolve individual vesicle positions and shapes in a condensate and notably the size and geometry of adhesion zones between vesicles. We hypothesize that the membrane tension induced by already formed adhesion zones then in turn limits the capability of vesicles to bind additional vesicles, resulting in a finite condensate size. In a simple numerical toy model we show that this effect can be accounted for by redistribution of effective binding particles on the vesicle surface, accounting for the synapsin-induced adhesion zone.
Language	English
Publishing date	2024-01-25
Publishing country	France
Document type	Journal Article
ZDB-ID	2004003-9
ISSN	1292-895X ; 1292-8941
ISSN (online)	1292-895X
ISSN	1292-8941
DOI	10.1140/epje/s10189-023-00404-5
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Article ; Online: Assembly principles and stoichiometry of a complete human kinetochore module.

Walstein, Kai / Petrovic, Arsen / Pan, Dongqing / Hagemeier, Birte / Vogt, Dorothee / Vetter, Ingrid R / Musacchio, Andrea

Science advances

2021 Volume 7, Issue 27

Abstract: Centromeres are epigenetically determined chromosomal loci that seed kinetochore assembly to promote chromosome segregation during cell division. CENP-A, a centromere-specific histone H3 variant, establishes the foundations for centromere epigenetic ... ...

Abstract	Centromeres are epigenetically determined chromosomal loci that seed kinetochore assembly to promote chromosome segregation during cell division. CENP-A, a centromere-specific histone H3 variant, establishes the foundations for centromere epigenetic memory and kinetochore assembly. It recruits the constitutive centromere-associated network (CCAN), which in turn assembles the microtubule-binding interface. How the specific organization of centromeric chromatin relates to kinetochore assembly and to centromere identity through cell division remains conjectural. Here, we break new ground by reconstituting a functional full-length version of CENP-C, the largest human CCAN subunit and a blueprint of kinetochore assembly. We show that full-length CENP-C, a dimer, binds stably to two nucleosomes and permits further assembly of all other kinetochore subunits in vitro with relative ratios closely matching those of endogenous human kinetochores. Our results imply that human kinetochores emerge from clustering multiple copies of a fundamental module and may have important implications for transgenerational inheritance of centromeric chromatin.
MeSH term(s)	Centromere/metabolism ; Centromere Protein A/genetics ; Centromere Protein A/metabolism ; Histones ; Humans ; Kinetochores/metabolism ; Nucleosomes
Chemical Substances	Centromere Protein A ; Histones ; Nucleosomes
Language	English
Publishing date	2021-06-30
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2810933-8
ISSN	2375-2548 ; 2375-2548
ISSN (online)	2375-2548
ISSN	2375-2548
DOI	10.1126/sciadv.abg1037
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Article ; Online: Streptococcus Gallolyticus endocarditis in patient with liver cirrhosis: a case report.

Radovanovic Spurnić, Aleksandra / Gmizić, Ivana / Milošević, Ivana / Petrović, Olga / Obradović, Danilo / Ristić, Arsen / Stevanović, Olja

Journal of infection in developing countries

2019 Volume 13, Issue 4, Page(s) 352–356

Abstract: Streptococcus gallolyticus (S. gallolyticus) bacteremia is commonly associated with endocarditis and diseases of gastrointestinal tract, especially with colorectal carcinoma. On the other side, it is rarely connected to liver disease, especially ... ...

Abstract	Streptococcus gallolyticus (S. gallolyticus) bacteremia is commonly associated with endocarditis and diseases of gastrointestinal tract, especially with colorectal carcinoma. On the other side, it is rarely connected to liver disease, especially alcoholic liver disease. A 44-old patient with a history of one month fever, pre-existing heart murmur and previous alcohol abuse, was treated in Clinic for Infectious and tropical diseases, Clinical Centre of Serbia (CCS), Belgrade. The diagnose of infective endocarditis (IE) of the aortic valve caused by S. gallolyticus has been established. Despite the conducted antibiotic treatment based on antibiogram, pericardial effusion with paracardial aortic abscess was diagnosed on the 9th day of treatment. Pericardiocentesis was done and 800 mL of haemorrhagic fluid was evacuated in the Clinic for Cardiology, CCS. Unfortunately, 20th day of hospitalization the patient died. Clinical autopsy confirmed endocarditis, liver cirrhosis and chronic pericarditis. Prognosis of the outcome of treatment of patient with endocarditis caused S. gallolyticus and liver cirrhosis is not optimistic. Therefore, significant attention should be given to patients with liver cirrhosis and febrile of unknown origin.
MeSH term(s)	Adult ; Alcoholism/complications ; Aortic Valve/pathology ; Endocarditis/complications ; Endocarditis/diagnosis ; Endocarditis/pathology ; Fatal Outcome ; Hospitals ; Humans ; Liver Cirrhosis/complications ; Male ; Pericardial Effusion/etiology ; Serbia ; Streptococcal Infections/diagnosis ; Streptococcal Infections/pathology ; Streptococcus gallolyticus/isolation & purification
Language	English
Publishing date	2019-04-30
Publishing country	Italy
Document type	Case Reports ; Journal Article
ZDB-ID	2394024-4
ISSN	1972-2680 ; 2036-6590
ISSN (online)	1972-2680
ISSN	2036-6590
DOI	10.3855/jidc.11126
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Article ; Online: BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis.

Singh, Priyanka / Pesenti, Marion E / Maffini, Stefano / Carmignani, Sara / Hedtfeld, Marius / Petrovic, Arsen / Srinivasamani, Anupallavi / Bange, Tanja / Musacchio, Andrea

Molecular cell

2020 Volume 81, Issue 1, Page(s) 67–87.e9

Abstract: Reflecting its pleiotropic functions, Polo-like kinase 1 (PLK1) localizes to various sub-cellular structures during mitosis. At kinetochores, PLK1 contributes to microtubule attachments and mitotic checkpoint signaling. Previous studies identified a ... ...

Abstract	Reflecting its pleiotropic functions, Polo-like kinase 1 (PLK1) localizes to various sub-cellular structures during mitosis. At kinetochores, PLK1 contributes to microtubule attachments and mitotic checkpoint signaling. Previous studies identified a wealth of potential PLK1 receptors at kinetochores, as well as requirements for various mitotic kinases, including BUB1, Aurora B, and PLK1 itself. Here, we combine ectopic localization, in vitro reconstitution, and kinetochore localization studies to demonstrate that most and likely all of the PLK1 is recruited through BUB1 in the outer kinetochore and centromeric protein U (CENP-U) in the inner kinetochore. BUB1 and CENP-U share a constellation of sequence motifs consisting of a putative PP2A-docking motif and two neighboring PLK1-docking sites, which, contingent on priming phosphorylation by cyclin-dependent kinase 1 and PLK1 itself, bind PLK1 and promote its dimerization. Our results rationalize previous observations and describe a unifying mechanism for recruitment of PLK1 to human kinetochores.
MeSH term(s)	CDC2 Protein Kinase/genetics ; CDC2 Protein Kinase/metabolism ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; HeLa Cells ; Histones/genetics ; Histones/metabolism ; Humans ; Kinetochores/metabolism ; Mitosis ; Protein Serine-Threonine Kinases/genetics ; Protein Serine-Threonine Kinases/metabolism ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/metabolism ; Polo-Like Kinase 1
Chemical Substances	CENPU protein, human ; Cell Cycle Proteins ; Histones ; Proto-Oncogene Proteins ; BUB1 protein, human (EC 2.7.11.1) ; Protein Serine-Threonine Kinases (EC 2.7.11.1) ; CDC2 Protein Kinase (EC 2.7.11.22) ; CDK1 protein, human (EC 2.7.11.22)
Language	English
Publishing date	2020-11-27
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1415236-8
ISSN	1097-4164 ; 1097-2765
ISSN (online)	1097-4164
ISSN	1097-2765
DOI	10.1016/j.molcel.2020.10.040
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Zs.A 5055: Show issues

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Article ; Online: Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices.

Jentoft, Ida M A / Bäuerlein, Felix J B / Welp, Luisa M / Cooper, Benjamin H / Petrovic, Arsen / So, Chun / Penir, Sarah Mae / Politi, Antonio Z / Horokhovskyi, Yehor / Takala, Iina / Eckel, Heike / Moltrecht, Rüdiger / Lénárt, Peter / Cavazza, Tommaso / Liepe, Juliane / Brose, Nils / Urlaub, Henning / Fernández-Busnadiego, Rubén / Schuh, Melina

Cell

2023 Volume 186, Issue 24, Page(s) 5308–5327.e25

Abstract: Mammalian oocytes are filled with poorly understood structures called cytoplasmic lattices. First discovered in the 1960s and speculated to correspond to mammalian yolk, ribosomal arrays, or intermediate filaments, their function has remained enigmatic ... ...

Abstract	Mammalian oocytes are filled with poorly understood structures called cytoplasmic lattices. First discovered in the 1960s and speculated to correspond to mammalian yolk, ribosomal arrays, or intermediate filaments, their function has remained enigmatic to date. Here, we show that cytoplasmic lattices are sites where oocytes store essential proteins for early embryonic development. Using super-resolution light microscopy and cryoelectron tomography, we show that cytoplasmic lattices are composed of filaments with a high surface area, which contain PADI6 and subcortical maternal complex proteins. The lattices associate with many proteins critical for embryonic development, including proteins that control epigenetic reprogramming of the preimplantation embryo. Loss of cytoplasmic lattices by knocking out PADI6 or the subcortical maternal complex prevents the accumulation of these proteins and results in early embryonic arrest. Our work suggests that cytoplasmic lattices enrich maternally provided proteins to prevent their premature degradation and cellular activity, thereby enabling early mammalian development.
MeSH term(s)	Pregnancy ; Animals ; Female ; Oocytes/metabolism ; Proteins/metabolism ; Embryo, Mammalian/metabolism ; Cytoskeleton ; Ribosomes ; Embryonic Development ; Mammals
Chemical Substances	Proteins
Language	English
Publishing date	2023-11-02
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	187009-9
ISSN	1097-4172 ; 0092-8674
ISSN (online)	1097-4172
ISSN	0092-8674
DOI	10.1016/j.cell.2023.10.003
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Zs.A 1167: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MG 58: Show issues

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Article: BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis

Singh, Priyanka / Pesenti, Marion E / Maffini, Stefano / Carmignani, Sara / Hedtfeld, Marius / Petrovic, Arsen / Srinivasamani, Anupallavi / Bange, Tanja / Musacchio, Andrea

Molecular cell. 2021 Jan. 07, v. 81, no. 1

2021

Abstract	Reflecting its pleiotropic functions, Polo-like kinase 1 (PLK1) localizes to various sub-cellular structures during mitosis. At kinetochores, PLK1 contributes to microtubule attachments and mitotic checkpoint signaling. Previous studies identified a wealth of potential PLK1 receptors at kinetochores, as well as requirements for various mitotic kinases, including BUB1, Aurora B, and PLK1 itself. Here, we combine ectopic localization, in vitro reconstitution, and kinetochore localization studies to demonstrate that most and likely all of the PLK1 is recruited through BUB1 in the outer kinetochore and centromeric protein U (CENP-U) in the inner kinetochore. BUB1 and CENP-U share a constellation of sequence motifs consisting of a putative PP2A-docking motif and two neighboring PLK1-docking sites, which, contingent on priming phosphorylation by cyclin-dependent kinase 1 and PLK1 itself, bind PLK1 and promote its dimerization. Our results rationalize previous observations and describe a unifying mechanism for recruitment of PLK1 to human kinetochores.
Keywords	cyclin-dependent kinase ; dimerization ; humans ; kinetochores ; microtubules ; mitosis ; phosphorylation
Language	English
Dates of publication	2021-0107
Size	p. 67-87.e9.
Publishing place	Elsevier Inc.
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	1415236-8
ISSN	1097-4164 ; 1097-2765
ISSN (online)	1097-4164
ISSN	1097-2765
DOI	10.1016/j.molcel.2020.10.040
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Article ; Online: Comparison of Custodiol® and modified St. Thomas cardioplegia for myocardial protection in coronary artery bypass grafting

Cvetković Dragan / Kočica Mladen / Šoškić Ljiljana / Vučićević Filip / Petrović Olga / Jovanović Ivana / Jovičić Snežana / Trifković Jelena / Kostovski Saša / Miličić Biljana / Karadžić Milica / Ristić Arsen / Savić Dragutin

Vojnosanitetski Pregled, Vol 77, Iss 11, Pp 1126-

2020 Volume 1134

Abstract: Background/Aim. Custodiol® is a hyperpolarizing cardioplegic solution which has been used in our national cardiac surgical practice exclusively for the heart transplant surgery. Owing to its numerous advantages over the standard depolarizing solutions, ... ...

Abstract	Background/Aim. Custodiol® is a hyperpolarizing cardioplegic solution which has been used in our national cardiac surgical practice exclusively for the heart transplant surgery. Owing to its numerous advantages over the standard depolarizing solutions, Custodiol® became cardioplegic solution of choice for all other cardiac surgical procedures in many cardio-surgical centers. This study evaluated myocardial protection by Custodiol® compared to modified St. Thomas cardioplegic solution in coronary artery bypass surgery. Methods. In a prospective four-month study, 110 consecutive adult patients who underwent primary isolated elective on-pump coronary artery bypass grafting (CABG) were randomized into the Custodiol® group (n = 54) and the St. Thomas groupa (n = 50), based on the type of administered cardioplegia; six patients were excluded. Cardiac protection was achieved as antegrade cold crystalloid cardioplegia by one of the solutions. Myocardial preservation was assessed through following outcomes: spontaneous rhythm restoration post cross-clamp, and postpoperative cardiac specific enzymes level, ejection fraction (EF) change, inotropic support, myocardial infarction (MI), atrial fibrillation (AF), and death. Results. Preoperative and intraoperative characteristics of patients in both groups were similar except for a considerably longer cross-clamp time in the Custodiol® group (49.1 ± 19.0 vs. 41.0 ± 12.9 minutes; p = 0.022). The Custodiol® group exhibited a higher rate of return to spontaneous rhythm compared to the St. Thomas group (31.5% vs. 20.0%, respectively; p = 0.267), lower rates of AF (20.4% vs. 28%, respectively; p = 0.496), MI (1.8% vs. 10.0%, respectively; p = 0.075) and inotropic support (9.0% vs. 12.0%, respectively; p = 0.651), albeit not statistically significant. There was an insignificant difference in peak value of troponin I between the Custodiol® and Thee St. Thomas group (5.0 ± 3.92 μg/L vs. 4.5 ± 3.39 μg/L, respectively; p = 0.755) and creatine kinase-MB (26.9 ± 15.4 μg/L vs. 28.5 ± 24.2 ...
Keywords	heart arrest ; induced ; custodiol-n solution ; cardiac surgical procedures ; postoperative period ; arrhythmias ; cardiac ; heart function tests ; mortality ; Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	Military Health Department, Ministry of Defance, Serbia
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Cadmium, lead, mercury and arsenic in fresh vegetables and vegetable products intended for human consumption in the Republic of Serbia, 2015-2017.

Lazović, Milana / Tomović, Vladimir / Vasiljević, Ivana / Kecojević, Isidora / Tomović, Mila / Martinović, Aleksandra / Žugić Petrović, Tanja / Danilović, Bojana / Vujadinović, Dragan / Tomašević, Igor / Smiljanić, Milenko / Đorđević, Vesna

Food additives & contaminants. Part B, Surveillance

2023 Volume 16, Issue 2, Page(s) 102–119

Abstract: The concentrations of cadmium (Cd), lead (Pb), mercury (Hg) and arsenic (As) were determined in 455 ...

Abstract	The concentrations of cadmium (Cd), lead (Pb), mercury (Hg) and arsenic (As) were determined in 455 samples of 27 species of vegetables and 28 different processed vegetables collected during the period from January 2015 to December 2017. Vegetables (n = 387) and vegetable products (n = 68) originated from 31 countries, including Serbia. The samples were analysed by inductively coupled plasma - optical emission spectrometry (ICP-OES). The concentrations of Cd, Pb, Hg and As in the vegetables and vegetable products were compared to the maximum levels set by the European Union and the Serbian legislation. The concentration of mercury was less than the limit of detection in each analysed sample. One or multiple measurable toxic metals (Cd, Pb and/or As) were found in 250 samples (54.9%; n = 455). According to the Regulations which were valid until the end of August 2021, the maximum levels of Cd, Pb and As were exceeded in 19 samples (4.2% of the samples of vegetable and vegetable products; n = 455), i.e. in 13 samples of vegetables: Cd in three, Pb in nine and As in one sample and in 6 samples of vegetables products: Cd in three, Pb in one and As in two samples. Regarding the new EU and Serbian legislation which is valid since September 2021 the maximum levels of Cd and Pb for vegetables and vegetable products were exceeded in 118 samples (25.9% of the samples of vegetable and vegetable products; n = 455), i.e. in 95 samples of vegetables: Cd in 67 and Pb in 28 samples and in 23 samples of vegetable products: Cd in 20 and Pb in 3 samples.
MeSH term(s)	Humans ; Cadmium/analysis ; Vegetables ; Arsenic/analysis ; Mercury/analysis ; Serbia ; Lead/analysis ; Food Contamination/analysis ; Vegetable Products/analysis ; Metals, Heavy/analysis
Chemical Substances	Cadmium (00BH33GNGH) ; Arsenic (N712M78A8G) ; Mercury (FXS1BY2PGL) ; Lead (2P299V784P) ; Metals, Heavy
Language	English
Publishing date	2023-02-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2447868-4
ISSN	1939-3229 ; 1939-3210
ISSN (online)	1939-3229
ISSN	1939-3210
DOI	10.1080/19393210.2023.2169359
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