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  1. Book: Psychopharmacology

    Meyer, Jerrold S. / Farrar, Andrew M. / Biezonski, Dominik / Yates, Jennifer R.

    drugs, the brain, and behavior

    2023  

    Author's details Jerrold S. Meyer, University of Massachusetts, Andrew M. Farrar, University of Massachusetts, Dominik Biezonski, Prevail Therapeutics, a wholly owned subsidiary of Eli Lilly and Company, Jennifer R. Yates, Lander University
    Keywords Psychotropic drugs / Pharmacokinetics ; Psychotropic drugs / Therapeutic use
    Language English
    Size xvi, 679, G-30, R-70, I-40 Seiten
    Edition Fourth edition
    Publisher Sinauer Associates, an imprint of Oxford University Press
    Publishing place New York
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT021576427
    ISBN 978-1-60535-987-8 ; 9781605359892 ; 1-60535-987-4 ; 1605359890
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Attempts to Influence the Value of Alcohol by Manipulating Social Influence and Context.

    Yates, Jack / Rose, Abigail K / Jones, Andrew

    Substance use & misuse

    2023  Volume 58, Issue 8, Page(s) 1053–1061

    Abstract: ... ...

    Abstract Background
    MeSH term(s) Humans ; Alcohol Drinking/psychology ; Friends/psychology ; Social Environment
    Language English
    Publishing date 2023-05-02
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 1310358-1
    ISSN 1532-2491 ; 1082-6084
    ISSN (online) 1532-2491
    ISSN 1082-6084
    DOI 10.1080/10826084.2023.2205532
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Modeling T Cell Fate.

    De Boer, Rob J / Yates, Andrew J

    Annual review of immunology

    2023  Volume 41, Page(s) 513–532

    Abstract: Many of the pathways that underlie the diversification of naive T cells into effector and memory subsets, and the maintenance of these populations, remain controversial. In recent years a variety of experimental tools have been developed that allow us to ...

    Abstract Many of the pathways that underlie the diversification of naive T cells into effector and memory subsets, and the maintenance of these populations, remain controversial. In recent years a variety of experimental tools have been developed that allow us to follow the fates of cells and their descendants. In this review we describe how mathematical models provide a natural language for describing the growth, loss, and differentiation of cell populations. By encoding mechanistic descriptions of cell behavior, models can help us interpret these new datasets and reveal the rules underpinning T cell fate decisions, both at steady state and during immune responses.
    MeSH term(s) Humans ; Animals ; T-Lymphocytes ; Cell Differentiation ; Immunologic Memory ; T-Lymphocyte Subsets ; CD8-Positive T-Lymphocytes
    Language English
    Publishing date 2023-05-02
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 604953-9
    ISSN 1545-3278 ; 0732-0582
    ISSN (online) 1545-3278
    ISSN 0732-0582
    DOI 10.1146/annurev-immunol-101721-040924
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Tailoring the pore size of expanded porphyrinoids for lanthanide selectivity.

    Malcomson, Thomas / Edwards-Yates, Lewis / Kerridge, Andrew

    RSC advances

    2023  Volume 13, Issue 41, Page(s) 28426–28433

    Abstract: Despite increase in demand, capacity for the recycling of rare earth elements remains limited, partly due to the inefficiencies with processes currently utilised in the separation of lanthanides. This study highlights the potential use of expanded ... ...

    Abstract Despite increase in demand, capacity for the recycling of rare earth elements remains limited, partly due to the inefficiencies with processes currently utilised in the separation of lanthanides. This study highlights the potential use of expanded porphyrinoids in lanthanide separation through selective binding, dependent on the tailored pore size of the macrocycle. Each emerging trend is subjected to multi-factored analysis to decompose the underlying source. Results promote the viability of size-based separation with preferential binding of larger lanthanum(iii) ions to amethyrin and isoamethyrin macrocycles, while smaller macrocycles such as pentaphyrin(0.0.0.0.0) present a preferential binding of lutetium(iii) ions. Additionally, the porphyrin(2.2.2.2) macrocycle shows a selectivity for gadolinium(iii) ions over both larger and smaller ions. An upper limit of applicable pore size is shown to be ≈2.8 Å, beyond which the formed complexes are predicted to be less stable than the corresponding nitrate complexes.
    Language English
    Publishing date 2023-09-27
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d3ra05710k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Child temperament and physical activity in young children.

    Yates, Julia / Tucker, Patricia / Johnson, Andrew M

    Child: care, health and development

    2023  Volume 49, Issue 5, Page(s) 898–905

    Abstract: Background: Children's temperament has been noted to influence their physical activity (PA) levels. Therefore, understanding the influence of temperament during the early years may be helpful for developing appropriate PA habits and tailoring ... ...

    Abstract Background: Children's temperament has been noted to influence their physical activity (PA) levels. Therefore, understanding the influence of temperament during the early years may be helpful for developing appropriate PA habits and tailoring interventions to align with different personality traits.
    Objective: The purpose of this study was to examine the relationship between child temperament and objectively-measured PA in preschool-aged children.
    Methods: Data were collected as part of the Supporting Physical Activity in the Childcare Environment (SPACE) and SPACE extension studies. Temperament data were collected using the validated Very Short Form of the Children's Behavior Questionnaire, which assessed three dimensions of temperament (i.e., surgency, negative affect and effortful control). Physical activity data were measured during childcare hours over the course of 5 days, using Actical® accelerometers. Total PA was summed, along with light and moderate-to-vigorous PA using age-specific cut-points. Three regression analyses were conducted to evaluate the prediction of PA by the dimensions of temperament.
    Results: A total of 399 participants (M
    Conclusion: Surgency is typified by a predisposition towards high activity levels; therefore, it is not surprising that it was the primary predictor of young children's PA. Future research may investigate methods of targeting PA interventions towards children with temperaments that may not predispose them to seeking out increased activity levels.
    MeSH term(s) Child, Preschool ; Humans ; Child ; Temperament ; Child Behavior ; Exercise ; Child Care ; Environment
    Language English
    Publishing date 2023-02-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 223039-2
    ISSN 1365-2214 ; 0305-1862
    ISSN (online) 1365-2214
    ISSN 0305-1862
    DOI 10.1111/cch.13098
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Gut Reaction: Habitual Dietary Nitrate Intake as a Modulator of Skeletal Muscle Contractile Function.

    Yates, Brandon A / Coggan, Andrew R

    The Journal of nutrition

    2021  Volume 151, Issue 5, Page(s) 1049–1050

    MeSH term(s) Dietary Supplements ; Eating ; Humans ; Muscle, Skeletal ; Nitrates
    Chemical Substances Nitrates
    Language English
    Publishing date 2021-02-03
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 218373-0
    ISSN 1541-6100 ; 0022-3166
    ISSN (online) 1541-6100
    ISSN 0022-3166
    DOI 10.1093/jn/nxab023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online: Replicating Relevance-Ranked Synonym Discovery in a New Language and Domain

    Yates, Andrew / Unterkalmsteiner, Michael

    2023  

    Abstract: Domain-specific synonyms occur in many specialized search tasks, such as when searching medical documents, legal documents, and software engineering artifacts. We replicate prior work on ranking domain-specific synonyms in the consumer health domain by ... ...

    Abstract Domain-specific synonyms occur in many specialized search tasks, such as when searching medical documents, legal documents, and software engineering artifacts. We replicate prior work on ranking domain-specific synonyms in the consumer health domain by applying the approach to a new language and domain: identifying Swedish language synonyms in the building construction domain. We chose this setting because identifying synonyms in this domain is helpful for downstream systems, where different users may query for documents (e.g., engineering requirements) using different terminology. We consider two new features inspired by the change in language and methodological advances since the prior work's publication. An evaluation using data from the building construction domain supports the finding from the prior work that synonym discovery is best approached as a learning to rank task in which a human editor views ranked synonym candidates in order to construct a domain-specific thesaurus. We additionally find that FastText embeddings alone provide a strong baseline, though they do not perform as well as the strongest learning to rank method. Finally, we analyze the performance of individual features and the differences in the domains.

    Comment: ECIR (1) 2019: 429-442
    Keywords Computer Science - Information Retrieval
    Subject code 004
    Publishing date 2023-10-02
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Book ; Online: Expert-sourcing Domain-specific Knowledge

    Unterkalmsteiner, Michael / Yates, Andrew

    The Case of Synonym Validation

    2023  

    Abstract: One prerequisite for supervised machine learning is high quality labelled data. Acquiring such data is, particularly if expert knowledge is required, costly or even impossible if the task needs to be performed by a single expert. In this paper, we ... ...

    Abstract One prerequisite for supervised machine learning is high quality labelled data. Acquiring such data is, particularly if expert knowledge is required, costly or even impossible if the task needs to be performed by a single expert. In this paper, we illustrate tool support that we adopted and extended to source domain-specific knowledge from experts. We provide insight in design decisions that aim at motivating experts to dedicate their time at performing the labelling task. We are currently using the approach to identify true synonyms from a list of candidate synonyms. The identification of synonyms is important in scenarios were stakeholders from different companies and background need to collaborate, for example when defining and negotiating requirements. We foresee that the approach of expert-sourcing is applicable to any data labelling task in software engineering. The discussed design decisions and implementation are an initial draft that can be extended, refined and validated with further application.

    Comment: REFSQ Workshops (NLP4RE). 2019
    Keywords Computer Science - Software Engineering
    Subject code 004
    Publishing date 2023-09-28
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Book ; Online: Generative Retrieval as Dense Retrieval

    Nguyen, Thong / Yates, Andrew

    2023  

    Abstract: Generative retrieval is a promising new neural retrieval paradigm that aims to optimize the retrieval pipeline by performing both indexing and retrieval with a single transformer model. However, this new paradigm faces challenges with updating the index ... ...

    Abstract Generative retrieval is a promising new neural retrieval paradigm that aims to optimize the retrieval pipeline by performing both indexing and retrieval with a single transformer model. However, this new paradigm faces challenges with updating the index and scaling to large collections. In this paper, we analyze two prominent variants of generative retrieval and show that they can be conceptually viewed as bi-encoders for dense retrieval. Specifically, we analytically demonstrate that the generative retrieval process can be decomposed into dot products between query and document vectors, similar to dense retrieval. This analysis leads us to propose a new variant of generative retrieval, called Tied-Atomic, which addresses the updating and scaling issues by incorporating techniques from dense retrieval. In experiments on two datasets, NQ320k and the full MSMARCO, we confirm that this approach does not reduce retrieval effectiveness while enabling the model to scale to large collections.

    Comment: GenIR@SIGIR2023
    Keywords Computer Science - Information Retrieval
    Subject code 004
    Publishing date 2023-06-20
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Surveillance and privacy as coevolving disruptions

    Andrew B. Whitford / Jeff Yates

    Policy Design and Practice, Pp 1-

    reflections on “notice and choice”

    2022  Volume 13

    Abstract: The last two decades have seen a dramatic rise in the ways governments, private industry, and other interests can access, gather, analyze, and employ information about citizens. Given the unique roles of practitioners from both the public and private ... ...

    Abstract The last two decades have seen a dramatic rise in the ways governments, private industry, and other interests can access, gather, analyze, and employ information about citizens. Given the unique roles of practitioners from both the public and private sectors in this policy ecosystem, we lay conceptual groundwork for coevolving technological, business, and policy disruptions. We focus on the “notice and choice” framework (which we consider a type of nudge) given changing conceptions of privacy in a world of evolving norms. Finally, we consider the difficult problem of clear guideposts for policy actors as they try to reconcile public demands for privacy with competing interests.
    Keywords Privacy ; data collection ; surveillance ; governance ; public opinion ; nudging ; Political science ; J ; Social Sciences ; H
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher Taylor & Francis Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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