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  1. Book ; Online: Advances in Infectious Diseases and Clinical Microbiology during the COVID-19 Pandemic

    Khan, Yusra Habib / Khan, Yusra Habib / Mallhi, Tauqeer Hussain / Khan, Tahir Mehmood / Salman, Muhammad

    2023  

    Keywords Humanities ; Social interaction ; n/a ; COVID-19 ; antibiotic therapy ; mortality ; female gender ; neoplasm history ; heart failure ; diabetes mellitus ; aspirin ; elderly population ; low molecular weight heparin ; pulmonary thromboembolism ; hospital stay ; parental knowledge ; HPV infection ; HPV vaccine ; children ; adolescents ; NSAID ; duration ; side effects ; safety ; vaccine hesitancy ; comorbidities ; hypertension ; hyperlipidemia ; pharmacovigilance ; SARS-CoV-2 ; sequencing ; Nanopore ; MinION ; Ion Torrent ; mediterranean diet ; inflammatory factors ; stress oxidative ; appetite ; antiviral ; clinical outcome ; coronavirus ; disease severity ; Saudi Arabia ; vaccine ; knowledge ; attitude ; perception ; survey ; questionnaire ; breakthrough infections ; neutralizing antibodies (NAbs) ; Omicron ; vaccines ; variants ; latent tuberculosis infection ; hemodialysis ; QuantiFERON-TB Gold Plus assay ; Lebanon ; dexamethasone ; tocilizumab ; epidural abscess ; bacteremia ; inflammatory markers ; therapeutic plasma exchange ; plasmapheresis ; monkeypox outbreak ; public health ; emergency ; Peru ; coinfections ; antimicrobials ; Colombia ; epidemiology ; superinfections ; telemedicine ; primary practice ; ophthalmological diseases ; HIV infection ; CMV retinitis ; tuberculosis verrucosa cutis (TBVC) ; multifocal ; infectious diseases ; tuberculosis
    Language English
    Size 1 electronic resource (250 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English
    HBZ-ID HT030645713
    ISBN 9783036594699 ; 3036594698
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Real time anatomical landmarks and abnormalities detection in gastrointestinal tract.

    Khan, Zeshan / Tahir, Muhammad Atif

    PeerJ. Computer science

    2023  Volume 9, Page(s) e1685

    Abstract: Gastrointestinal (GI) endoscopy is an active research field due to the lethal cancer diseases in the GI tract. Cancer treatments result better if diagnosed early and it increases the survival chances. There is a high miss rate in the detection of the ... ...

    Abstract Gastrointestinal (GI) endoscopy is an active research field due to the lethal cancer diseases in the GI tract. Cancer treatments result better if diagnosed early and it increases the survival chances. There is a high miss rate in the detection of the abnormalities in the GI tract during endoscopy or colonoscopy due to the lack of attentiveness, tiring procedures, or the lack of required training. The procedure of the detection can be automated to the reduction of the risks by identifying and flagging the suspicious frames. A suspicious frame may have some of the abnormality or the information about anatomical landmark in the frame. The frame then can be analysed for the anatomical landmarks and the abnormalities for the detection of disease. In this research, a real-time endoscopic abnormalities detection system is presented that detects the abnormalities and the landmarks. The proposed system is based on a combination of handcrafted and deep features. Deep features are extracted from lightweight MobileNet convolutional neural network (CNN) architecture. There are some of the classes with a small inter-class difference and a higher intra-class differences, for such classes the same detection threshold is unable to distinguish. The threshold of such classes is learned from the training data using genetic algorithm. The system is evaluated on various benchmark datasets and resulted in an accuracy of 0.99 with the F1-score of 0.91 and Matthews correlation coefficient (MCC) of 0.91 on Kvasir datasets and F1-score of 0.93 on the dataset of DowPK. The system detects abnormalities in real-time with the detection speed of 41 frames per second.
    Language English
    Publishing date 2023-12-19
    Publishing country United States
    Document type Journal Article
    ISSN 2376-5992
    ISSN (online) 2376-5992
    DOI 10.7717/peerj-cs.1685
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Editorial: Immunotherapeutics development against Hantaviruses.

    Qamar, Muhammad Tahir Ul / Ahmad, Sajjad / Khan, Abbas / Wei, Dongqing

    Frontiers in immunology

    2024  Volume 15, Page(s) 1377137

    MeSH term(s) Orthohantavirus ; RNA Viruses ; Immunotherapy
    Language English
    Publishing date 2024-02-07
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2024.1377137
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Synthesis, Characterizations, Hirshfeld Surface Analysis, DFT, and NLO Study of a Schiff Base Derived from Trifluoromethyl Amine.

    Tahir, Muhammad Nawaz / Ashfaq, Muhammad / Munawar, Khurram Shahzad / Khan, Ahsan Ullah / Asghar, Muhammad Adnan / Ahamad, Tansir / Ojha, Suvash Chandra

    ACS omega

    2024  Volume 9, Issue 2, Page(s) 2325–2338

    Abstract: We synthesized an imine-based (Schiff base) crystalline organic chromophore, i.e., ( ...

    Abstract We synthesized an imine-based (Schiff base) crystalline organic chromophore, i.e., (
    Language English
    Publishing date 2024-01-04
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c05199
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Healthcare professionals' understanding and perception of drug-related issues linked to off-label pharmacological medications used for COVID-19.

    Munir, Muhammad Zeeshan / Khan, Amer Hayat / Khan, Tahir Mehmood

    Expert review of anti-infective therapy

    2024  , Page(s) 1–7

    Abstract: Background: To evaluate the opinions of healthcare workers regarding drug therapy problems linked to anti-infective medicines used for the treatment of COVID-19 infection in Pakistan.: Research methodology: This cross-sectional study was conducted ... ...

    Abstract Background: To evaluate the opinions of healthcare workers regarding drug therapy problems linked to anti-infective medicines used for the treatment of COVID-19 infection in Pakistan.
    Research methodology: This cross-sectional study was conducted from January to October 2022 using a self-administered questionnaire developed by the authors, having three sections: demographics, knowledge, and perception. The study was validated by research experts and pilot-tested on 30 subjects. The study included medical doctors, nurses, pharmacists from Punjab's government and private medical institutes.
    Results: In this study, 382 of 400 participants replied. The mean knowledge score was 9.52 (SD 2.97), showing that participants had adequate knowledge of COVID-19 pharmacological interventions. The knowledge scores were significantly higher of those who treated COVID-19 patients and were from Lahore. Many doctors considered that elderly patients and those with blood disorders were at greater risk of experiencing drug-related problems. Most pharmacists support electronic prescription systems. Many doctors thought the lack of unified treatment guidelines, multiple prescribers, and self-medication were key obstacles in managing COVID-19 patients.
    Conclusion: Most respondents had adequate knowledge. Older patients with comorbidities are at risk of adverse effects. Self-medication, polypharmacy, and multiple prescriptions can lead to misdiagnosis and complications. Electric prescriptions, team effort, and training programs can decrease these issues.
    Language English
    Publishing date 2024-01-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2181279-2
    ISSN 1744-8336 ; 1478-7210
    ISSN (online) 1744-8336
    ISSN 1478-7210
    DOI 10.1080/14787210.2024.2310004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6106: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Revolutionizing Cancer Care: Advances in Carbon-Based Materials for Diagnosis and Treatment.

    Khan, Muhammad Zubair / Tahir, Danial / Asim, Muhammad / Israr, Muhammad / Haider, Ali / Xu, Dan Dan

    Cureus

    2024  Volume 16, Issue 1, Page(s) e52511

    Abstract: Cancer involves intricate pathological mechanisms marked by complexities such as cytotoxicity, drug resistance, stem cell proliferation, and inadequate specificity in current chemotherapy approaches. Cancer therapy has embraced diverse nanomaterials ... ...

    Abstract Cancer involves intricate pathological mechanisms marked by complexities such as cytotoxicity, drug resistance, stem cell proliferation, and inadequate specificity in current chemotherapy approaches. Cancer therapy has embraced diverse nanomaterials renowned for their unique magnetic, electrical, and optical properties to address these challenges. Despite the expanding corpus of knowledge in this area, there has been less advancement in approving nano drugs for use in clinical settings. Nanotechnology, and more especially the development of intelligent nanomaterials, has had a profound impact on cancer research and treatment in recent years. Due to their large surface area, nanoparticles can adeptly encapsulate diverse compounds. Furthermore, the modification of nanoparticles is achievable through a broad spectrum of bio-based substrates, including DNA, aptamers, RNA, and antibodies. This functionalization substantially enhances their theranostic capabilities. Nanomaterials originating from biological sources outperform their conventionally created counterparts, offering advantages such as reduced toxicity, lower manufacturing costs, and enhanced efficiency. This review uses carbon nanomaterials, including graphene-based materials, carbon nanotubes (CNTs) based nanomaterials, and carbon quantum dots (CQDs), to give a complete overview of various methods used in cancer theranostics. We also discussed their advantages and limitations in cancer diagnosis and treatment settings. Carbon nanomaterials might significantly improve cancer theranostics and pave the way for fresh tumor diagnosis and treatment approaches. More study is needed to determine whether using nano-carriers for targeted medicine delivery may increase material utilization. More insight is required to explore the correlation between heightened cytotoxicity and retention resulting from increased permeability.
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.52511
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Cellulose nanocrystals boosted hydrophobically associated self-healable conductive hydrogels for the application of strain sensors and electronic devices.

    Ullah, Rafi / Shah, Luqman Ali / Khan, Muhammad Tahir

    International journal of biological macromolecules

    2024  Volume 260, Issue Pt 1, Page(s) 129376

    Abstract: Currently, hydrogel-based flexible devices become hot areas for scientists in the field of electronic devices, artificial intelligence, human motion detection, and electronic skin. These devices show responses to external stimuli (mechanical signals) and ...

    Abstract Currently, hydrogel-based flexible devices become hot areas for scientists in the field of electronic devices, artificial intelligence, human motion detection, and electronic skin. These devices show responses to external stimuli (mechanical signals) and convert them into electrical signals (resistance, current, and voltage). However, the applications of the hydrogel-based sensor are hampered due to low mechanical properties, high time response, low fatigue resistance, low self-healing nature, and low sensing range. Herein, a strain sensing conductive hydrogel constructed from the CNCs (cellulose nanocrystal) reinforced, in which acrylamide and butyl acrylate work as hydrophilic and hydrophobic monomers respectively. The incorporation of CNCs in the polymeric system has a direct effect on their mechanical properties. The hydrogel having a high amount of CNCs (C
    MeSH term(s) Humans ; Cellulose ; Hydrogels ; Artificial Intelligence ; Electric Conductivity ; Cinacalcet ; Electronics
    Chemical Substances Cellulose (9004-34-6) ; Hydrogels ; Cinacalcet (UAZ6V7728S)
    Language English
    Publishing date 2024-01-22
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2024.129376
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2374: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Ameliorative effect of crocin on post-thaw quality, fertility-associated gene expression and fertilization potential of buffalo (Bubalus bubalis) bull sperm.

    Khan, Ghulam Shabbir / Tahir, Muhammad Zahid / Zahoor, Muhammad Yasir / Rahman, Hifz-Ul- / Riaz, Amjad

    Reproduction in domestic animals = Zuchthygiene

    2024  Volume 59, Issue 1, Page(s) e14519

    Abstract: Buffalo bull sperm suffer more cryoinjuries due to lipid peroxidation of high structural polyunsaturated fatty acid contents than cattle sperm. Consequently, the post-thaw fertilization potential of buffalo bull sperm is compromised. Crocin is a ... ...

    Abstract Buffalo bull sperm suffer more cryoinjuries due to lipid peroxidation of high structural polyunsaturated fatty acid contents than cattle sperm. Consequently, the post-thaw fertilization potential of buffalo bull sperm is compromised. Crocin is a carotenoid known for its antioxidant potential through scavenging reactive oxygen species. Objectives of the current study were to investigate the effect of crocin addition in the semen extender on post-thaw quality, fertility-associated gene expression and fertilization potential of buffalo bull sperm. Semen samples (n = 32) from four Nili-Ravi buffalo bulls were extended with tris-citric acid extender containing different concentrations of crocin (0 mM; control, 0.5, 1, 1.5 and 2 mM). The extended semen was packed in 0.5 mL French straws (25 × 10
    MeSH term(s) Male ; Animals ; Cattle ; Female ; Pregnancy ; Buffaloes ; Semen ; Semen Analysis/veterinary ; bcl-2-Associated X Protein ; Sperm Motility ; Bison ; Carotenoids/pharmacology ; Spermatozoa ; Fertility ; Antioxidants/pharmacology ; DNA ; Gene Expression ; Fertilization
    Chemical Substances crocin (877GWI46C2) ; bcl-2-Associated X Protein ; Carotenoids (36-88-4) ; Antioxidants ; DNA (9007-49-2)
    Language English
    Publishing date 2024-01-25
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1015187-4
    ISSN 1439-0531 ; 0936-6768
    ISSN (online) 1439-0531
    ISSN 0936-6768
    DOI 10.1111/rda.14519
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 2117: Show issues

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  9. Article ; Online: Real time anatomical landmarks and abnormalities detection in gastrointestinal tract

    Zeshan Khan / Muhammad Atif Tahir

    PeerJ Computer Science, Vol 9, p e

    2023  Volume 1685

    Abstract: Gastrointestinal (GI) endoscopy is an active research field due to the lethal cancer diseases in the GI tract. Cancer treatments result better if diagnosed early and it increases the survival chances. There is a high miss rate in the detection of the ... ...

    Abstract Gastrointestinal (GI) endoscopy is an active research field due to the lethal cancer diseases in the GI tract. Cancer treatments result better if diagnosed early and it increases the survival chances. There is a high miss rate in the detection of the abnormalities in the GI tract during endoscopy or colonoscopy due to the lack of attentiveness, tiring procedures, or the lack of required training. The procedure of the detection can be automated to the reduction of the risks by identifying and flagging the suspicious frames. A suspicious frame may have some of the abnormality or the information about anatomical landmark in the frame. The frame then can be analysed for the anatomical landmarks and the abnormalities for the detection of disease. In this research, a real-time endoscopic abnormalities detection system is presented that detects the abnormalities and the landmarks. The proposed system is based on a combination of handcrafted and deep features. Deep features are extracted from lightweight MobileNet convolutional neural network (CNN) architecture. There are some of the classes with a small inter-class difference and a higher intra-class differences, for such classes the same detection threshold is unable to distinguish. The threshold of such classes is learned from the training data using genetic algorithm. The system is evaluated on various benchmark datasets and resulted in an accuracy of 0.99 with the F1-score of 0.91 and Matthews correlation coefficient (MCC) of 0.91 on Kvasir datasets and F1-score of 0.93 on the dataset of DowPK. The system detects abnormalities in real-time with the detection speed of 41 frames per second.
    Keywords Medical image analysis ; GI tract diagnostics ; Genetic algorithm ; Threshold selection ; Endoscopic disease detection ; Computer vision ; Electronic computers. Computer science ; QA75.5-76.95
    Subject code 006
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher PeerJ Inc.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  10. Article: Impact of a pharmacist-led educational intervention on knowledge, attitude, and practice toward the rational use of antibiotics among healthcare workers in a secondary care hospital in Punjab, Pakistan.

    Afzal, Shairyar / Khan, Farman Ullah / Aqeel, Muhammad Tahir / Ullah, Matti / Bajwa, Mishal / Akhtar, Masoom / Majid, Muhammad

    Frontiers in pharmacology

    2024  Volume 14, Page(s) 1327576

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2024-01-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1327576
    Database MEDical Literature Analysis and Retrieval System OnLINE

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