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  1. Article ; Online: Early diagnosis of parathyroid carcinoma: A challenging for physicians.

    Campennì, Alfredo / Ruggeri, Rosaria Maddalena

    Clinical endocrinology

    2022  Volume 98, Issue 2, Page(s) 273–274

    MeSH term(s) Humans ; Parathyroid Neoplasms/diagnosis ; Parathyroid Neoplasms/surgery ; Parathyroid Glands ; Hyperparathyroidism ; Early Diagnosis ; Physicians ; Parathyroidectomy ; Hypercalcemia/diagnosis ; Parathyroid Hormone
    Chemical Substances Parathyroid Hormone
    Language English
    Publishing date 2022-08-04
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 121745-8
    ISSN 1365-2265 ; 0300-0664
    ISSN (online) 1365-2265
    ISSN 0300-0664
    DOI 10.1111/cen.14807
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 814: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Nodal metastasis in noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP).

    Campennì, Alfredo / Torregrossa, Liborio / Ruggeri, Rosaria Maddalena / Ovčariček, Petra Petranović / Siracusa, Massimiliano / Giovanella, Luca

    Endocrine

    2024  

    Abstract: The term noninvasive tumor with a follicular growth pattern and nuclear features of papillary thyroid cancer (NIFTP) is used to describe a tumor currently considered as a pre-malignant lesion for which a conservative therapeutic approach (i.e., lobectomy ...

    Abstract The term noninvasive tumor with a follicular growth pattern and nuclear features of papillary thyroid cancer (NIFTP) is used to describe a tumor currently considered as a pre-malignant lesion for which a conservative therapeutic approach (i.e., lobectomy without radioiodine therapy) is strongly suggested. However, some patients with NIFTP and loco-regional or distant metastases have been already reported. We present an adult male patient with a final histological diagnosis of NIFTP and lymph node metastasis noted at post-therapy whole-body scintigraphy performed some days after radioiodine therapy.
    Language English
    Publishing date 2024-02-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1194484-5
    ISSN 1559-0100 ; 1355-008X ; 0969-711X
    ISSN (online) 1559-0100
    ISSN 1355-008X ; 0969-711X
    DOI 10.1007/s12020-024-03719-1
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3884: Show issues Location:
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  3. Article: Commentary: Fish and the thyroid: A Janus Bifrons relationship caused by pollutants and the omega-3 polyunsaturated fatty acids.

    Hrelia, Silvana / Barbalace, Maria Cristina / Cannavò, Salvatore / Ruggeri, Rosaria Maddalena

    Frontiers in endocrinology

    2023  Volume 14, Page(s) 1138245

    MeSH term(s) Animals ; Environmental Pollutants ; Thyroid Gland ; Fatty Acids, Omega-3 ; Diet
    Chemical Substances Environmental Pollutants ; Fatty Acids, Omega-3
    Language English
    Publishing date 2023-04-11
    Publishing country Switzerland
    Document type Journal Article ; Comment
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1138245
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  4. Article ; Online: Comment on: Report of One Case of Malignancy Among 17 Autonomous Thyroid Nodules in Children and Adolescents.

    Campennì, Alfredo / Ruggeri, Rosaria Maddalena / Giovanella, Luca

    Journal of paediatrics and child health

    2021  Volume 57, Issue 12, Page(s) 2039–2040

    MeSH term(s) Adolescent ; Biopsy, Fine-Needle ; Child ; Humans ; Thyroid Neoplasms ; Thyroid Nodule/diagnostic imaging
    Language English
    Publishing date 2021-09-15
    Publishing country Australia
    Document type Letter ; Comment
    ZDB-ID 1024476-1
    ISSN 1440-1754 ; 1034-4810
    ISSN (online) 1440-1754
    ISSN 1034-4810
    DOI 10.1111/jpc.15743
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    Zs.A 227: Show issues Location:
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  5. Article ; Online: Challenges and pitfalls in the management of endocrine toxicities from immune checkpoint inhibitors: a case presentation of synchronous thyrotoxicosis and primary adrenal insufficiency in a melanoma patient.

    Spagnolo, Calogera Claudia / Campo, Irene / Campennì, Alfredo / Cardile, Davide / Cannavò, Salvatore / Silvestris, Nicola / Santarpia, Mariacarmela / Ruggeri, Rosaria Maddalena

    Hormones (Athens, Greece)

    2024  

    Abstract: Background: Immune checkpoint inhibitors have revolutionized the therapeutic approach to several solid tumors, becoming the standard of care for cancer treatment in different disease settings. Despite the fact that these agents are better tolerated than ...

    Abstract Background: Immune checkpoint inhibitors have revolutionized the therapeutic approach to several solid tumors, becoming the standard of care for cancer treatment in different disease settings. Despite the fact that these agents are better tolerated than conventional chemotherapy, their use is associated with a specific toxicity profile, so-called immune-related adverse events (irAEs), that can involve several organs. Endocrine irAEs are among the most frequent toxicities (around 10 to 16%) and include hypophysitis, thyroid disorders, adrenalitis, and diabetes mellitus. Some of them may be life-threatening if not promptly recognized (such as diabetic ketoacidosis and acute adrenal crisis).
    Case presentation: A 55-year-old woman with a personal history of euthyroid Hashimoto's thyroiditis was diagnosed with a metastatic melanoma, BRAF wild type. Under treatment with anti-PD-1 pembrolizumab, she developed thyrotoxicosis followed by hypothyroidism due to destructive thyroiditis and concurrent primary adrenal insufficiency due to adrenalitis.
    Conclusions: The simultaneous occurrence of adrenal and thyroid autoimmune diseases, resembling autoimmune polyendocrine syndrome type 2, may occur as a rare but serious side effect of ICI treatment. It often presents with abrupt onset and rapid evolution towards polyglandular insufficiency. Physicians should be aware of the potential association of two or more endocrine disorders and careful monitoring of endocrine function is needed during ICI therapy.
    Language English
    Publishing date 2024-02-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2075912-5
    ISSN 2520-8721 ; 1109-3099
    ISSN (online) 2520-8721
    ISSN 1109-3099
    DOI 10.1007/s42000-024-00535-0
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    Zs.A 5613: Show issues Location:
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  6. Article ; Online: Malignant thyroid nodule topography as additional risk factor for lymph-node metastases in differentiated thyroid cancer patients.

    Campennì, Alfredo / Siracusa, Massimiliano / Ruggeri, Rosaria Maddalena / Giovanella, Luca / Baldari, Sergio

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2022  Volume 279, Issue 12, Page(s) 5969–5970

    MeSH term(s) Humans ; Thyroid Nodule/pathology ; Lymphatic Metastasis/pathology ; Thyroid Neoplasms/surgery ; Thyroid Neoplasms/pathology ; Lymph Nodes/pathology ; Risk Factors
    Language English
    Publishing date 2022-04-27
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-022-07411-w
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    Ul II Zs.50: Show issues Location:
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  7. Article: Thyroid Cancer Persistence in Patients with Unreliable Thyroglobulin Measurement: Circulating microRNA as Candidate Alternative Biomarkers.

    Campennì, Alfredo / Aguennouz, M'hammed / Siracusa, Massimiliano / Alibrandi, Angela / Polito, Francesca / Oteri, Rosaria / Baldari, Sergio / Ruggeri, Rosaria Maddalena / Giovanella, Luca

    Cancers

    2022  Volume 14, Issue 22

    Abstract: Background: We aimed to evaluate the role of circulating miRNAs as a biomarker of the persistence of papillary thyroid cancer (PTC) in patients with an "uninformative" thyroglobulin (Tg) measurement.: Methods: We prospectively enrolled 49 consecutive ...

    Abstract Background: We aimed to evaluate the role of circulating miRNAs as a biomarker of the persistence of papillary thyroid cancer (PTC) in patients with an "uninformative" thyroglobulin (Tg) measurement.
    Methods: We prospectively enrolled 49 consecutive PTC patients with Tg-positive antibodies (TgAb) who had undergone a (near)-total thyroidectomy and
    Results: The response to the initial therapy was assessed according to the 2015 ATA criteria. A decrease in 50% or more of serum miRNA over time was observed in 41/49 PTC patients, who showed an excellent response (ER), but six and two patients were classified to have an indeterminate/incomplete biochemical or incomplete structural response to initial therapy.
    Conclusion: Serum miRNA kinetics emerge as a promising biomarker for the early detection of a persistent disease in PTC patients with uninformative Tg results.
    Language English
    Publishing date 2022-11-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers14225620
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  8. Article: The Influence of Food Regimes on Oxidative Stress: A Permutation-Based Approach Using the NPC Test.

    Zirilli, Agata / Ruggeri, Rosaria Maddalena / Barbalace, Maria Cristina / Hrelia, Silvana / Giovanella, Luca / Campennì, Alfredo / Cannavò, Salvatore / Alibrandi, Angela

    Healthcare (Basel, Switzerland)

    2023  Volume 11, Issue 16

    Abstract: 1) Background: This paper aims to assess the existence of significant differences between two dietary regimes (omnivorous vs. semi-vegetarian) with reference to some oxidative stress markers (SOD, GPx, TRxR, GR, AGEs, and AOPPs) using non-parametric ... ...

    Abstract (1) Background: This paper aims to assess the existence of significant differences between two dietary regimes (omnivorous vs. semi-vegetarian) with reference to some oxidative stress markers (SOD, GPx, TRxR, GR, AGEs, and AOPPs) using non-parametric combination methodology based on a permutation test. (2) Methods: At the endocrinology unit of Messina University Hospital, two hundred subjects were asked to fill out a questionnaire about their dietary habits. None were under any pharmacological treatment. Using the NPC test, all comparisons were performed stratifying patients according to gender, age (≤40 or >40 years), BMI (normal weight vs. overweight), physical activity (sedentary vs. active lifestyle), TSH, FT4 levels in quartiles, and diagnosis of Hashimoto's thyroiditis. We evaluated differences in oxidative stress parameters in relation to two examined dietary regimes (omnivorous vs. semi-vegetarian). (3) Results: The antioxidant parameters GPx and TRxR were significantly lower in subjects with an omnivorous diet than in semi-vegetarians, particularly in females, both age groups, subjects with normal weight, those not affected by Hashimoto's thyroiditis, and both the sedentary and active lifestyle groups. Finally, the AGE and AOPP markers were significantly lower in semi-vegetarians. (4) Conclusion: Thanks to the NPC methodology, we can state that dietary patterns exert a significant influence on some oxidative stress parameters.
    Language English
    Publishing date 2023-08-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare11162263
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  9. Article ; Online: Autoimmune Thyroid Disorders: The Mediterranean Diet as a Protective Choice.

    Ruggeri, Rosaria Maddalena / Barbalace, Maria Cristina / Croce, Laura / Malaguti, Marco / Campennì, Alfredo / Rotondi, Mario / Cannavò, Salvatore / Hrelia, Silvana

    Nutrients

    2023  Volume 15, Issue 18

    Abstract: Autoimmune thyroid diseases are on the rise worldwide, and such a rapid increase is mainly driven by environmental factors related to changed lifestyles in "modern" societies. In this context, diet seems to play a crucial role. An unhealthy high-energy ... ...

    Abstract Autoimmune thyroid diseases are on the rise worldwide, and such a rapid increase is mainly driven by environmental factors related to changed lifestyles in "modern" societies. In this context, diet seems to play a crucial role. An unhealthy high-energy diet, rich in animal fat and proteins, salt and refined sugars (the so-called "Western diet") negatively influences the risk of autoimmunity by altering the immune balance and the gut microbiota composition, enhancing oxidative stress and promoting inflammation. In contrast, the Mediterranean diet represents a unique model of healthy eating, characterized by a high intake of food from vegetable sources, a low consumption of saturated fats in favor of unsaturated fats (mainly, olive oil), a moderate consumption of fish (typically, the small oily fishes) and dairy products, as well as a moderate consumption of wine at meals, and a low intake of meat. Thanks to its nutritional components, the Mediterranean Diet positively influences immune system function, gut microbiota composition, and redox homeostasis, exerting anti-oxidants, anti-inflammatory, and immunomodulatory effects. The present review was aimed at exploring the existing knowledge on the correlations between dietary habits and thyroid autoimmunity, to evaluate the role of the Mediterranean diet as a protective model.
    Language English
    Publishing date 2023-09-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15183953
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Comment on "Prevalence of undifferentiated inflammatory arthropathy in patients with Hashimoto's thyroiditis in an endocrinology clinic" by Luis M. Valderrama-Hinds and co-workers. Int J Rheum Dis 2019; 22: 1985-1989.

    Giuffrida, Giuseppe / Campennì, Alfredo / Trimarchi, Francesco / Ruggeri, Rosaria Maddalena

    International journal of rheumatic diseases

    2020  Volume 23, Issue 4, Page(s) 597–598

    MeSH term(s) Arthritis ; Hashimoto Disease ; Humans ; Prevalence ; Thyroiditis, Autoimmune
    Language English
    Publishing date 2020-03-05
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2426924-4
    ISSN 1756-185X ; 1756-1841
    ISSN (online) 1756-185X
    ISSN 1756-1841
    DOI 10.1111/1756-185X.13820
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    Zs.A 6098: Show issues Location:
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