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Article ; Online: Surveillance Compliance and Quality of Life Assessment Among Surgical Patients with Familial Adenomatous Polyposis Syndrome.

Alhassan, Noura / Helmi, Hadeel / Alzamil, Abdullah / Alshammari, Afraj / Altamimi, Atheer / Alshammari, Sulaiman / Bin Traiki, Thamer / Albanyan, Saleh / AlKhayal, Khayal / Zubaidi, Ahmad / Al-Obeed, Omar

Journal of epidemiology and global health

2024 Volume 14, Issue 1, Page(s) 86–93

Abstract: Background: Familial adenomatous polyposis (FAP) syndrome has a near-100% lifetime risk of colorectal cancer. Early surveillance and prophylactic surgery have been advocated to reduce this risk. However, the surveillance practices among FAP individuals ... ...

Abstract	Background: Familial adenomatous polyposis (FAP) syndrome has a near-100% lifetime risk of colorectal cancer. Early surveillance and prophylactic surgery have been advocated to reduce this risk. However, the surveillance practices among FAP individuals in Saudi Arabia are unknown. We aimed to explore surveillance compliance in our population, as well as the disease impact on their quality of life (QoL). Methods: All patients with FAP who underwent surgical resection at King Saud University Medical City between 2016 and 2022 were included. Demographic data, clinical features, family history, and compliance with surveillance were collected and analyzed. QoL questionnaires: Short-form health survey (SF-36) and European Organization for Research and Treatment (EORTC) were conducted by phone interview. Results: A total of 14 patients were included with an average age of 25 years. Three patients (21.4%) were the first of their family members to develop FAP. Nine patients (64%) were untested for genetic mutation due to lack of referral to geneticists. The compliance rate toward both pre-operative colonoscopy and upper endoscopy were 78%. However, 38% and 27% compliance rates were observed toward initial and post-operative colonoscopy, respectively. The compliance rate was 14% toward thyroid ultrasound. QoL scores varied among patients, with a mean score above 60 across all SF-36 domains. Conclusion: An overall poor compliance was observed among our participants, particularly toward thyroid ultrasound. Increased health awareness and patient education are essential. In addition, the importance of surveillance and genetic counseling should be emphasized among physicians treating these patients.
MeSH term(s)	Humans ; Adenomatous Polyposis Coli/surgery ; Adenomatous Polyposis Coli/psychology ; Adenomatous Polyposis Coli/diagnosis ; Quality of Life ; Male ; Female ; Adult ; Saudi Arabia/epidemiology ; Patient Compliance/statistics & numerical data ; Patient Compliance/psychology ; Young Adult ; Middle Aged ; Surveys and Questionnaires ; Colonoscopy/statistics & numerical data ; Colonoscopy/psychology ; Adolescent ; Population Surveillance/methods
Language	English
Publishing date	2024-01-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2645324-1
ISSN	2210-6014 ; 2210-6014
ISSN (online)	2210-6014
ISSN	2210-6014
DOI	10.1007/s44197-023-00171-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Coronavirus Disease 2019-Associated Bilateral Massive Pulmonary Emboli Caused Death in a Healthy 35-Year-Old Patient.

Al Sbihi, Ali F / Manasrah, Nouraldeen / Kosti, Jorgena / Alhassan, Sulaiman

Cureus

2020 Volume 12, Issue 9, Page(s) e10213

Abstract: Coronavirus disease 2019 (COVID-19) infection was first reported in December 2019. Within three months, the virus caused a global pandemic that has affected the whole world's dynamics. Many causes of death due to COVID-19 infection have been identified, ... ...

Abstract	Coronavirus disease 2019 (COVID-19) infection was first reported in December 2019. Within three months, the virus caused a global pandemic that has affected the whole world's dynamics. Many causes of death due to COVID-19 infection have been identified, involving but not limited to atypical acute respiratory distress syndrome, hypercoagulability, renal failure, and a proinflammatory cytokine storm, often associated with multiorgan failure. We report the case of a young, previously healthy patient who developed massive pulmonary emboli due to COVID-19 infection, resulting in death.
Keywords	covid19
Language	English
Publishing date	2020-09-02
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.10213
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Article ; Online: Extensive Calcified Fibrothorax.

Alhassan, Sulaiman / Fasanya, Adebayo / Thirumala, Raghu

American journal of respiratory and critical care medicine

2017 Volume 195, Issue 4, Page(s) e25–e26

Language	English
Publishing date	2017-02-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	1180953-x
ISSN	1535-4970 ; 0003-0805 ; 1073-449X
ISSN (online)	1535-4970
ISSN	0003-0805 ; 1073-449X
DOI	10.1164/rccm.201606-1265IM
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Article: Awareness of Risk Factors for Coronary Artery Disease in the Population of Al-Majma'ah Region, Saudi Arabia.

Almutairi, Ahmed H / Alhassan, Sultan A / Almutairi, Faisal A / Alharthi, Bader A / Aljabr, Sulaiman A / Alabdulmonem, Riyadh A / Altariqi, Waleed M / Alaboody, Ziad M / Almutairy, Adel K / AlQahtani, Majed A / Albejede, Osama M / Alrajeh, Saud A / Alshahrani, Mohammed D

Cureus

2024 Volume 16, Issue 1, Page(s) e52497

Abstract: Background: Coronary artery disease (CAD) is a significant global health concern and a leading cause of morbidity and mortality. As a complex cardiovascular condition, CAD arises from the accumulation of atherosclerotic plaques within the coronary ... ...

Abstract	Background: Coronary artery disease (CAD) is a significant global health concern and a leading cause of morbidity and mortality. As a complex cardiovascular condition, CAD arises from the accumulation of atherosclerotic plaques within the coronary arteries, leading to restricted blood flow to the heart muscle. While CAD has been extensively studied, its prevalence remains a challenge, particularly in diverse populations with distinct cultural and lifestyle practices. Objectives: To assess the awareness of risk factors for CAD in the population of Al-Majma'ah Region, Saudi Arabia. Methods: The purpose of this cross-sectional descriptive study was to determine participants' awareness of CAD risk factors among the population of Al-Majma'ah Region, Saudi Arabia. It was conducted by the use of a self-administered questionnaire that had been validated in prior research publications. Sociodemographic information as well as the prevalence of cardiovascular disease risk factors were covered in the survey. The data analysis was done using IBM SPSS Statistics for Windows, Version 26 (Released 2019; IBM Corp., Armonk, New York, United States). Results: A total of 919 individuals were enrolled in the current study after meeting the inclusion criteria. The results showed that most of the respondents 626 (68.1%) had a good level of awareness, 261 (28.4%) had a fair level of awareness, while only 32 (3.5%) of the respondents had a poor level of CAD risk factors awareness. Conclusion: The majority of participants had a good level of knowledge regarding CAD risk factors. The correlation between monthly income and awareness of coronary artery risk factors was statistically significant.
Language	English
Publishing date	2024-01-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.52497
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Article ; Online: Correction: The clinical outcomes of COVID-19 critically ill patients co-infected with other respiratory viruses: a multicenter, cohort study.

Al Sulaiman, Khalid / Aljuhani, Ohoud / Badreldin, Hisham A / Korayem, Ghazwa B / Alenazi, Abeer A / Alharbi, Ahlam H / Alghamdi, Albandari / Alhubaishi, Alaa / Altebainawi, Ali F / Bosaeed, Mohammad / Alotaibi, Rand / Alawad, Ahad / Alnajjar, Nirvana / Saleh, Khalid Bin / Sait, Walaa A / Alsohimi, Samiah / Alanizy, Meshari M / Almuqbil, Sarah A / Al Sulaihim, Ibrahim /

Vishwakarma, Ramesh / Alalawi, Mai / Alhassan, Fatimah / Alghnam, Suliman

BMC infectious diseases

2023 Volume 23, Issue 1, Page(s) 103

Language	English
Publishing date	2023-02-22
Publishing country	England
Document type	Published Erratum
ZDB-ID	2041550-3
ISSN	1471-2334 ; 1471-2334
ISSN (online)	1471-2334
ISSN	1471-2334
DOI	10.1186/s12879-023-08072-8
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Article: Eflornithine Hydrochloride-Loaded Electrospun Nanofibers as a Potential Face Mask for Hirsutism Application.

Almuwallad, Shuruq S / Alzahrani, Dunia A / Aburayan, Walaa S / Alfahad, Ahmed J / Alsulami, Khulud A / Aodah, Alhassan H / Alsudir, Samar A / Alhudaithi, Sulaiman S / Tawfik, Essam A

Pharmaceutics

2023 Volume 15, Issue 9

Abstract: Hirsutism is a distressing condition that can affect women's self-esteem due to the excessive amount of hair growth in different body parts, including the face. A temporary managing option is to develop a self-care routine to remove unwanted hair through ...

Abstract	Hirsutism is a distressing condition that can affect women's self-esteem due to the excessive amount of hair growth in different body parts, including the face. A temporary managing option is to develop a self-care routine to remove unwanted hair through shaving or waxing. Laser or electrolysis are alternative methods, but in some cases, the use of medications, such as the topical cream Vaniqa
Language	English
Publishing date	2023-09-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527217-2
ISSN	1999-4923
ISSN	1999-4923
DOI	10.3390/pharmaceutics15092343
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Article: Physicochemical characterization and cancer cell antiproliferative effect of silver-doped magnesia nanoparticles.

Al-Fahdawi, Mohamed Qasim / Aldoghachi, Ahmed Faris / Alhassan, Fatah H / Al-Doghachi, Faris A J / Alshwyeh, Hussah Abdullah / Rasedee, Abdullah / Alnasser, Sulaiman Mohammed / Al-Qubaisi, Mothanna Sadiq / Ibrahim, Wisam Nabeel

Heliyon

2023 Volume 9, Issue 5, Page(s) e15560

Abstract: Silver-doped magnesia nanoparticles (Ag/MgO) were synthesized using the precipitation method and characterized by various techniques such as X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), thermal gravimetric analysis (TGA), ... ...

Abstract	Silver-doped magnesia nanoparticles (Ag/MgO) were synthesized using the precipitation method and characterized by various techniques such as X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), thermal gravimetric analysis (TGA), Brunner-Emmett-Teller (BET) surface area measurements, and dispersive X-ray spectroscopy (EDX). The morphology of Ag/MgO nanoparticles was determined by transmission and scanning electron microscopy, which revealed cuboidal shaped nanoparticles with sizes ranging from 31 to 68 nm and an average size of 43.5 ± 10.6 nm. The anticancer effects of Ag/MgO nanoparticles were evaluated on human colorectal (HT29) and lung adenocarcinoma (A549) cell lines, and their caspase-3, -8, and -9 activities, as well as Bcl-2, Bax, p53, cytochrome C protein expressions were estimated. Ag/MgO nanoparticles showed selective toxicity towards HT29 and A549 cells while remaining relatively innocuous towards the normal human colorectal, CCD-18Co, and lung, MRC-5 cells. The IC
Language	English
Publishing date	2023-04-17
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e15560
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Article ; Online: The impact of preoperative total parenteral nutrition on the surgical complications of Crohn's disease: A retrospective cohort study.

Traiki, Thamer A Bin / Alshammari, Sulaiman A / Aljomah, Nadia A / Alsalouli, Monirah M / Altawil, Esraa S / Abdulla, Maha-Hamadien / Alhassan, Noura S / Alkhayal, Khayal A

Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association

2023 Volume 29, Issue 3, Page(s) 158–163

Abstract: Background: Crohn's disease (CD) is associated with malnutrition, an independent risk factor for surgical morbidity and mortality in more than 65% of patients, with a significant impact on disease outcomes. In this single-center retrospective cohort ... ...

Abstract	Background: Crohn's disease (CD) is associated with malnutrition, an independent risk factor for surgical morbidity and mortality in more than 65% of patients, with a significant impact on disease outcomes. In this single-center retrospective cohort study, we aimed to investigate the impact of total parenteral nutrition (TPN) on the surgical outcomes of patients with CD. Methods: This study included patients with CD who underwent abdominal surgery. We compared patients who received preoperative total parenteral nutrition (TPN group) to those who did not (non-TPN group). Prolonged oral intolerance, albumin level <30 g/L, and body mass index <18.5 were the main indications for TPN. We evaluated postoperative surgical complications in both groups. Results: Between January 2010 and October 2018, 169 eligible patients underwent abdominal surgery. The TPN and non-TPN groups included 40 and 129 patients, respectively. The mean albumin level was significantly lower in the TPN group (P = 0.013). Laparoscopic surgery was performed in 76.9% of the patients, with a conversion rate of 11.6%. Infectious and non-infectious complications developed in 8.9% and 16% of patients, respectively. Surgical complications were comparable between the groups (P >0.05). Conclusions: Despite oral intake intolerance and severe disease in the TPN group, the surgical complications were comparable between the groups.
MeSH term(s)	Humans ; Crohn Disease/surgery ; Crohn Disease/complications ; Retrospective Studies ; Preoperative Care ; Parenteral Nutrition, Total/adverse effects ; Postoperative Complications/epidemiology ; Albumins
Chemical Substances	Albumins
Language	English
Publishing date	2023-01-02
Publishing country	India
Document type	Journal Article
ZDB-ID	2299174-8
ISSN	1998-4049 ; 1319-3767
ISSN (online)	1998-4049
ISSN	1319-3767
DOI	10.4103/sjg.sjg_425_22
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Article ; Online: Oncological outcomes of elective versus emergency surgery for colon cancer: A tertiary academic center experience.

Bin Traiki, Thamer A / AlShammari, Sulaiman A / AlRabah, Razan N / AlZahrani, Amirah M / Alshenaifi, Saud T / Alhassan, Noura S / Abdulla, Maha-Hamadien / Zubaidi, Ahmad M / Al-Obeed, Omar A / Alkhayal, Khayal A

Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association

2023 Volume 29, Issue 5, Page(s) 316–322

Abstract: Background: In this study, we aimed to identify the oncological outcomes in colon cancer patients who underwent elective versus emergency curative resection.: Methods: All patients who underwent curative resection for colon cancer between July 2015 ... ...

Abstract	Background: In this study, we aimed to identify the oncological outcomes in colon cancer patients who underwent elective versus emergency curative resection. Methods: All patients who underwent curative resection for colon cancer between July 2015 and December 2019 were retrospectively reviewed and analyzed. Patients were divided into two groups based on the presentation into elective and emergency groups. Results: A total of 215 patients with colon cancer were admitted and underwent curative surgical resection. Of those, 145 patients (67.4%) were elective cases, and 70 (32.5%) were emergency cases. Family history of malignancy was positive in 44 patients (20.5%) and significantly more common in the emergency group (P = 0.016). The emergency group had higher T and TNM stages (P = 0.001). The 3-year survival rate was 60.9% and significantly less in the emergency group (P = 0.026). The mean duration from surgery to recurrence, 3-year disease-free survival, and overall survival were 1.19, 2.81, and 3.11, respectively. Conclusion: Elective group was associated with better 3-year survival, longer overall, and 3-year disease-free survival compared to the emergency group. The disease recurrence rate was comparable in both groups, mainly in the first two years after curative resection.
MeSH term(s)	Humans ; Treatment Outcome ; Retrospective Studies ; Neoplasm Recurrence, Local ; Colonic Neoplasms/surgery ; Colonic Neoplasms/pathology ; Disease-Free Survival
Language	English
Publishing date	2023-04-04
Publishing country	India
Document type	Journal Article
ZDB-ID	2299174-8
ISSN	1998-4049 ; 1319-3767
ISSN (online)	1998-4049
ISSN	1319-3767
DOI	10.4103/sjg.sjg_31_23
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Article ; Online: Clinical outcomes of lower gastrointestinal bleeding in patients managed with lower endoscopy: A tertiary center results.

Alhassan, Noura S / Altwuaijri, Mansour A / Alshammari, Sulaiman A / Alshehri, Khaled M / Alkhayyal, Yazeed A / Alfaiz, Fahad A / Alomar, Mohammad O / Alkhowaiter, Saad S / Amaar, Nuha Y Al / Traiki, Thamer A Bin / Khayal, Khayal A Al

Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association

2023 Volume 30, Issue 2, Page(s) 83–88

Abstract: Background: Lower gastrointestinal bleeding (LGIB) is an urgent presentation with increasing prevalence and remains a common cause of hospitalization. The clinical outcome can vary based on several factors, including the cause of bleeding, its severity, ...

Abstract	Background: Lower gastrointestinal bleeding (LGIB) is an urgent presentation with increasing prevalence and remains a common cause of hospitalization. The clinical outcome can vary based on several factors, including the cause of bleeding, its severity, and the effectiveness of management strategies. The aim of this study is to provide a comprehensive report on the clinical outcomes observed in patients with LGIB who underwent lower endoscopy. Methods: All patients who underwent emergency lower endoscopy for fresh bleeding per rectum, from May 2015 to December 2021, were included. The primary outcome was to identify the rate of rebleeding after initial control of bleeding. The second was to measure the clinical outcomes and the potential predictors leading to intervention and readmission. Results: A total of 84 patients were included. Active bleeding was found in 20% at the time of endoscopy. Rebleeding within 90 days occurred in 6% of the total patients; two of which (2.38%) were within the same admission. Ninety-day readmission was reported in 19% of the cases. Upper endoscopy was performed in 32.5% of the total cases and was found to be a significant predictor for intervention (OR 4.1, P = 0.013). Personal history of inflammatory bowel disease (IBD) and initial use of sigmoidoscopy were found to be significant predictors of readmission [(OR 5.09, P = 0.008) and (OR 5.08, P = 0.019)]. Conclusions: LGIB is an emergency that must be identified and managed using an agreed protocol between all associated services to determine who needs upper GI endoscopy, ICU admission, or emergency endoscopy within 12 hours.
MeSH term(s)	Humans ; Endoscopy, Gastrointestinal ; Gastrointestinal Hemorrhage/therapy ; Hospitalization ; Inflammatory Bowel Diseases
Language	English
Publishing date	2023-12-15
Publishing country	India
Document type	Journal Article
ZDB-ID	2299174-8
ISSN	1998-4049 ; 1319-3767
ISSN (online)	1998-4049
ISSN	1319-3767
DOI	10.4103/sjg.sjg_316_23
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