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  1. Book ; Online: A Practical Guide for Pediatric Nuclear Medicine

    Bar-Sever, Zvi / Giammarile, Francesco / Israel, Ora / Nadel, Helen

    2023  

    Author's details edited by Zvi Bar-Sever, Francesco Giammarile, Ora Israel, Helen Nadel
    Keywords Nuclear medicine ; Pediatrics ; Radiology ; Oncology ; Orthopedics
    Language English
    Size 1 Online-Ressource (XVIII, 231 p. 118 illus., 71 illus. in color)
    Edition 1st ed. 2023
    Publisher Springer Berlin Heidelberg ; Imprint: Springer
    Publishing place Berlin, Heidelberg
    Document type Book ; Online
    HBZ-ID HT030360558
    ISBN 978-3-662-67631-8 ; 9783662676301 ; 9783662676325 ; 9783662676332 ; 3-662-67631-1 ; 3662676303 ; 366267632X ; 3662676338
    DOI 10.1007/978-3-662-67631-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: A Practical Guide for Pediatric Nuclear Medicine

    Bar-Sever, Zvi / Giammarile, Francesco / Israel, Ora / Nadel, Helen / Israel, Ora

    2023  

    Keywords Nuclear medicine ; Paediatric medicine ; Radiology ; Oncology ; Orthopaedics & fractures ; Hybrid imaging ; Theranostics ; Management of childhood diseases ; SPECT/CT ; PET/CT
    Language English
    Size 1 electronic resource (231 pages)
    Publisher Springer Nature
    Publishing place Berlin, Heidelberg
    Document type Book ; Online
    Note English
    HBZ-ID HT030612440
    ISBN 9783662676301 ; 3662676303
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Feedback Beamforming in the Time Domain.

    Herscovici, Zvi Aharon / Cohen, Israel

    Sensors (Basel, Switzerland)

    2024  Volume 24, Issue 7

    Abstract: Real-time source localization is crucial for high-end automation and artificial intelligence (AI) products. However, a low signal-to-noise ratio (SNR) and limited processing time can reduce localization accuracy. This work proposes a new architecture for ...

    Abstract Real-time source localization is crucial for high-end automation and artificial intelligence (AI) products. However, a low signal-to-noise ratio (SNR) and limited processing time can reduce localization accuracy. This work proposes a new architecture for a time-domain feedback-based beamformer that meets real-time processing demands. The main objective of this design is to locate reflective sources by estimating their direction of arrival (DOA) and signal range. Incorporating a feedback mechanism in this architecture refines localization precision, a unique aspect of this approach. We conducted an in-depth analysis to compare the effectiveness of time-domain feedback beamforming against conventional time-domain methods, highlighting their benefits and limitations. Our evaluation of the proposed architecture, based on critical performance indicators such as peak-to-sidelobe ratio, mainlobe width, and directivity factor, demonstrates its ability to improve beamformer effectiveness significantly.
    Language English
    Publishing date 2024-03-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s24072179
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Lower Incidence of Hypoglycemia With Angiotensin Receptor Blocker Versus ACE Inhibitor Therapy in People With or Without Diabetes.

    Khanimov, Israel / Zingerman, Boris / Rozen-Zvi, Benaya / Shimonov, Mordechai / Leibovitz, Eyal

    Clinical diabetes : a publication of the American Diabetes Association

    2024  Volume 42, Issue 2, Page(s) 300–307

    Abstract: ... to the internal medicine departments of a tertiary hospital in the Tel Aviv district of Israel. The authors found ...

    Abstract This article describes a study examining the association between treatment with ACE inhibitors or angiotensin receptor blockers (ARBs) and incident hypoglycemia in patients with or without diabetes who were admitted to the internal medicine departments of a tertiary hospital in the Tel Aviv district of Israel. The authors found that treatment with ARBs, but not ACE inhibitors, compared with treatment with neither, was associated with a reduced risk of hypoglycemia regardless of diabetes status.
    Language English
    Publishing date 2024-01-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1025953-3
    ISSN 0891-8929
    ISSN 0891-8929
    DOI 10.2337/cd23-0039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Reversing a Model of Parkinson's Disease With In Situ Converted Nigral Neurons.

    Israel, Zvi / Asch, Nir

    Movement disorders : official journal of the Movement Disorder Society

    2020  Volume 35, Issue 11, Page(s) 1955

    MeSH term(s) Dopaminergic Neurons ; Humans ; Parkinson Disease ; Substantia Nigra
    Language English
    Publishing date 2020-10-05
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 607633-6
    ISSN 1531-8257 ; 0885-3185
    ISSN (online) 1531-8257
    ISSN 0885-3185
    DOI 10.1002/mds.28306
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 238: Show issues

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  6. Article ; Online: The effect of dopaminergic therapy on intraoperative microelectrode recordings for subthalamic deep brain stimulation under GA: Letter to the editor.

    Israel, Zvi

    Acta neurochirurgica

    2016  Volume 158, Issue 5, Page(s) 1013

    MeSH term(s) Deep Brain Stimulation ; Humans ; Microelectrodes ; Parkinson Disease ; Subthalamic Nucleus
    Language English
    Publishing date 2016-03-01
    Publishing country Austria
    Document type Letter ; Comment
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-016-2756-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    Uk I Zs.180: Show issues Location:
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  7. Article ; Online: Epilepsy following herpes simplex encephalitis - A case series.

    Hersh, Nir / Ben Zvi, Haim / Goldstein, Lilach / Steiner, Israel / Benninger, Felix

    Epilepsy research

    2023  Volume 192, Page(s) 107137

    Abstract: Background: Herpes simplex encephalitis (HSE) is associated with severe mortality and morbidity. Its incidence is estimated at 1:250 000, and the typical symptomatology of acute disease including headaches, mental state disturbances, confusion, ... ...

    Abstract Background: Herpes simplex encephalitis (HSE) is associated with severe mortality and morbidity. Its incidence is estimated at 1:250 000, and the typical symptomatology of acute disease including headaches, mental state disturbances, confusion, sleepiness, and seizures. The chronic phase of the disease is occasionally characterized by epilepsy and neurological deficits.
    Study rationale: The present retrospective single-center study aims to identify risk factors for predicting the development of epilepsy (epileptogenesis) following HSE.
    Methods: Medical records were screened for patients older than 18 years, hospitalized between January 2005 and September 2019 with a diagnosis of "encephalitis" and "herpes simplex virus, HSV" infection. HSE diagnosis was based on an analysis of the cerebrospinal fluid with positive HSV testing results.
    Results: Twenty-three patients fit our inclusion criteria: fever and behavioral changes, followed by seizures, were reported in 58.3 % of patients. On follow-up (59.7 ± 38.8 months), eight patients (34.8 %) developed epilepsy. Pathological imaging and EEG were correlated with acute symptomatic seizures (ASS). ASS was associated with an 8-fold risk increase to develop post-encephalitis epilepsy (PE). PE was associated with younger age but not with CSF results, imaging, or EEG.
    Conclusion: Our retrospective single-center study on PE, following HSE, shows that younger age and ASS were associated with PE. Brain imaging, CSF analysis, and EEG were not associated with the development of epilepsy following HSE.
    MeSH term(s) Humans ; Encephalitis, Herpes Simplex/complications ; Encephalitis, Herpes Simplex/diagnostic imaging ; Retrospective Studies ; Herpes Simplex/complications ; Herpes Simplex/diagnosis ; Simplexvirus ; Epilepsy/complications ; Seizures/complications
    Language English
    Publishing date 2023-04-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 632939-1
    ISSN 1872-6844 ; 0920-1211
    ISSN (online) 1872-6844
    ISSN 0920-1211
    DOI 10.1016/j.eplepsyres.2023.107137
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2193: Show issues Location:
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  8. Article: MicroRNA expression changes in Parkinson's disease (PD) patients' leukocytes prior to and following deep brain stimulation (DBS).

    Lilach, Soreq / Hagai, Bergman / Zvi, Israel / Hermona, Soreq / Wael, Mohamed

    American journal of neurodegenerative disease

    2021  Volume 10, Issue 3, Page(s) 28–33

    Abstract: The second most prevalent neurodegenerative disorder worldwide in the elderly is Parkinson's disease (PD). It is a major risk factor for aging. ...

    Abstract The second most prevalent neurodegenerative disorder worldwide in the elderly is Parkinson's disease (PD). It is a major risk factor for aging.
    Language English
    Publishing date 2021-06-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2695563-5
    ISSN 2165-591X
    ISSN 2165-591X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Entrainment to sleep spindles reflects dissociable patterns of connectivity between cortex and basal ganglia.

    Mizrahi-Kliger, Aviv D / Kaplan, Alexander / Israel, Zvi / Bergman, Hagai

    Cell reports

    2022  Volume 40, Issue 12, Page(s) 111367

    Abstract: Sleep spindles are crucial for learning in the cortex and basal ganglia (BG) because they facilitate the reactivation of previously active neuronal ensembles. Studying field potentials (FPs) and spiking in the cortex and BG during sleep in non-human ... ...

    Abstract Sleep spindles are crucial for learning in the cortex and basal ganglia (BG) because they facilitate the reactivation of previously active neuronal ensembles. Studying field potentials (FPs) and spiking in the cortex and BG during sleep in non-human primates following pre-sleep learning, we show that FP sleep spindles are widespread in the BG and are similar to cortical spindles in morphology, spectral content, and response to the pre-sleep task. Further, BG spindles are concordant with electroencephalogram (EEG) spindles and associated with increased cortico-BG correlation. However, spindles across the BG differ markedly in their entrainment of local spiking. The spiking activity of striatal projection neurons exhibits consistent phase locking to striatal and EEG spindles, producing phase windows of peaked cross-region spindling. In contrast, firing in other BG nuclei is not entrained to either local or EEG sleep spindles. These results suggest corticostriatal synapses as the main hub for offline cortico-BG communication.
    MeSH term(s) Animals ; Basal Ganglia/physiology ; Cerebral Cortex/physiology ; Corpus Striatum ; Electroencephalography ; Neurons/physiology ; Sleep/physiology
    Language English
    Publishing date 2022-09-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2649101-1
    ISSN 2211-1247 ; 2211-1247
    ISSN (online) 2211-1247
    ISSN 2211-1247
    DOI 10.1016/j.celrep.2022.111367
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Cognitive Effects of Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease with GBA1 Pathogenic Variants.

    Pal, Gian D / Corcos, Daniel M / Metman, Leo Verhagen / Israel, Zvi / Bergman, Hagai / Arkadir, David

    Movement disorders : official journal of the Movement Disorder Society

    2023  Volume 38, Issue 12, Page(s) 2155–2162

    Abstract: Genetic subtyping of patients with Parkinson's disease (PD) may assist in predicting the cognitive and motor outcomes of subthalamic deep brain stimulation (STN-DBS). Practical questions were recently raised with the emergence of new data regarding ... ...

    Abstract Genetic subtyping of patients with Parkinson's disease (PD) may assist in predicting the cognitive and motor outcomes of subthalamic deep brain stimulation (STN-DBS). Practical questions were recently raised with the emergence of new data regarding suboptimal cognitive outcomes after STN-DBS in individuals with PD associated with pathogenic variants in glucocerebrosidase gene (GBA1-PD). However, a variety of gaps and controversies remain. (1) Does STN-DBS truly accelerate cognitive deterioration in GBA1-PD? If so, what is the clinical significance of this acceleration? (2) How should the overall risk-to-benefit ratio of STN-DBS in GBA1-PD be established? (3) If STN-DBS has a negative effect on cognition in GBA1-PD, how can this effect be minimized? (4) Should PD patients be genetically tested before STN-DBS? (5) How should GBA1-PD patients considering STN-DBS be counseled? We aim to summarize the currently available relevant data and detail the gaps and controversies that exist pertaining to these questions. In the absence of evidence-based data, all authors strongly agree that clinicians should not categorically deny DBS to PD patients based solely on genotype (GBA1 status). We suggest that PD patients considering DBS may be offered genetic testing for GBA1, where available and feasible, so the potential risks and benefits of STN-DBS can be properly weighed by both the patient and clinician. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
    MeSH term(s) Humans ; Cognition ; Cognition Disorders ; Deep Brain Stimulation ; Parkinson Disease/genetics ; Parkinson Disease/therapy ; Parkinson Disease/complications ; Subthalamic Nucleus/physiology
    Chemical Substances GBA protein, human (EC 3.2.1.45)
    Language English
    Publishing date 2023-11-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 607633-6
    ISSN 1531-8257 ; 0885-3185
    ISSN (online) 1531-8257
    ISSN 0885-3185
    DOI 10.1002/mds.29647
    Database MEDical Literature Analysis and Retrieval System OnLINE

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